Efus023031.1
Basic Information
- Insect
- Ennomos fuscantarius
- Gene Symbol
- ZFX
- Assembly
- GCA_905220475.1
- Location
- HG992053.1:3984824-4004500[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.98 93 4.5 1.5 1 23 352 375 352 375 0.95 2 11 0.001 0.094 13.9 0.7 1 23 382 404 382 404 0.98 3 11 0.4 38 5.7 1.1 1 23 408 431 408 431 0.90 4 11 0.52 49 5.4 1.9 1 23 438 460 438 460 0.82 5 11 2.5e-05 0.0024 18.9 0.8 2 23 465 487 464 487 0.93 6 11 2.4e-05 0.0022 19.0 1.1 1 23 493 515 493 515 0.98 7 11 0.0041 0.39 12.0 0.5 2 21 527 546 527 551 0.93 8 11 4.2e-05 0.004 18.2 2.6 1 23 559 582 559 582 0.94 9 11 0.00012 0.011 16.8 0.8 1 23 587 610 587 610 0.98 10 11 8.2e-07 7.7e-05 23.6 3.3 2 23 618 639 617 639 0.97 11 11 2.3e-06 0.00022 22.2 1.3 1 23 645 668 645 668 0.95
Sequence Information
- Coding Sequence
- ATGGATAATATAAAAGAAGAAATATCATTTCAACTGCTCTGTAATGCATGCCTGTGCGTTGGAAGGACTCTGTACCAGATTACAAATGAAAAACTAAAGCGGTTTTACCTTAACGCATTGAGTGAAATACCTCTATGTGGGGTGCCAAAGGTGCTGCCCAGCATCTGCTGGGAGTGTAAAGTTCTTCTAAAGAAATCATTAGACTTCCGTGAGCAAGTTAAAGACTCATACCGGATACTCATGGCTTATACTAGCGAGAATCTCCACGAATGCCTGCTAACAGACGTTTCTCGGCCACCTCGGTTGAAGATCAAAAACAATGATAGTATCAACATTGAACCAGACTATACCTATGATGTAGACGATAAATGCTTGGGCGATAAGAATTCCACCGAATATAATGCAAACATGAAGACAAAAGTGGTTCCAATCAAAGTAAATATTGTTGACAAATGCAATGCCAGTCCGTCATACACAGATATATCACAAGAGTACGGGAGTAATACGCAGGAGGTGTTTGTAAAGGATGAGCTAAAGATTGAAGATATTGCATGCGATGGAGGTCAGTACAGCCAGGCGATTTTTGAACGAGCTAATGCTGTTGGTCTCTACCGACCTCTACAGCGGGTGGGAGGGCAGGCAAGTGGGGGGAAACTAGCTGGCGGGCACCCCTGGGGTGCGAGCCTCGGCTTGGGCCGTTGCCGGGATAAGGGGATCGAGAAGACTACGTCCACTAGAAGAGTGGACCCTATTGAAAATATAGATTTCTCCGATGGACAGACGGAGGATCCTAAATCGTTGCATGCGGACAACATAGATGAAATAGCCAATGAAATTCAGTCGATAATCGGCGATGTGAAGAATAGTAAGAAAAAAACGAAATCAAAAAAGAGTAAGCAAATCAAAGGGAAAGTTAAAAAGAGGAAAACTAAGAGGTTTAAAGAAGTAATATCACTAGACATACCCAGCATACAAACCATAGATCTGGGATACGAAGAGATGCTGTTAGAAAGAGAGAGAGAATTCACCAAAGATAATTACGTAAACGCAGAGTATAAATGCGAAACTTGCATACTGGGTTTCACCTATGACAAGTCTTATAAAACTCATTTGATTAATAAACATTCGCCGGAAATCGGCAATTTCACGTGTCCTATTTGCAAAACCGTTTTGAATTCAGTCGATTCTTTCACTATTCATTACAAACGGCATATGAGAAGATATGAATGTAGCATATGTCAAAAACGTACAATGGACATGAAAGTTATGCAGCAACATTATTATTCATCTCACGATATATCACTCAAGAAATACAAGTGCAGAGATTGCGGAAAAATATCCAATTCGATAGATTCCCACCGCTACCATACAGGCACCCACAAGTCAAGGGTTCAATGTACTGAATGCGATAAAACGTTTAGACACAGAGGCGGCCTGCTCAACCATAGACTTGCTGTACACGAGTTGCGCAACATGTTTCCGTGCAACCAGTGCGACAAGGTTTTCCGTTGGAAGAACAGCCTTAAGCGGCATTTAGACACGCACGATGCTAAGAATAAGTCACCATCAGGCGCGGCTTATTGCACTCTATGCAGTGTTAGCTTCGCATCACTGGGCTCCTACCAACGTCACATGAACAATAGTTTGAAGCACGTTACCAAAGATGACTTTAGGTTCATTTGCGATCATTGCAATAGGCGGTTTTCTGACAAGACGAAACTGCGAGATCATATCGAAGAGAAGCACCTACATAAGACATACAAATGCCAGATATGTTTAAAGACATCAAAAAACCGTGTAAACTTGGACCAGCACATACGCAACGTTCATAAAGGAAGACCAAACAACAAAATGTGTCACCATTGTGGAAAAGGATTCCCGACTAAAGTCCAGCTTGAATCCCATATAAGGACACACACTGGCGAAAGGCCTTTCATCTGCGAATACTGTCCTACAACATTCTCTCAACAGTCCAACTTGTACAAGCATAATAGACAGGTACACCTCAATTTAAAAACCAAGCGTTATCCGATCGCAAAGAAGCGGAAAGACGACAAACCTCCGGAACTGACGATGGTACCGGCAGAAATACCTCTCGAATACCCTGTCGATATAGACTTCCCTATTTGA
- Protein Sequence
- MDNIKEEISFQLLCNACLCVGRTLYQITNEKLKRFYLNALSEIPLCGVPKVLPSICWECKVLLKKSLDFREQVKDSYRILMAYTSENLHECLLTDVSRPPRLKIKNNDSINIEPDYTYDVDDKCLGDKNSTEYNANMKTKVVPIKVNIVDKCNASPSYTDISQEYGSNTQEVFVKDELKIEDIACDGGQYSQAIFERANAVGLYRPLQRVGGQASGGKLAGGHPWGASLGLGRCRDKGIEKTTSTRRVDPIENIDFSDGQTEDPKSLHADNIDEIANEIQSIIGDVKNSKKKTKSKKSKQIKGKVKKRKTKRFKEVISLDIPSIQTIDLGYEEMLLEREREFTKDNYVNAEYKCETCILGFTYDKSYKTHLINKHSPEIGNFTCPICKTVLNSVDSFTIHYKRHMRRYECSICQKRTMDMKVMQQHYYSSHDISLKKYKCRDCGKISNSIDSHRYHTGTHKSRVQCTECDKTFRHRGGLLNHRLAVHELRNMFPCNQCDKVFRWKNSLKRHLDTHDAKNKSPSGAAYCTLCSVSFASLGSYQRHMNNSLKHVTKDDFRFICDHCNRRFSDKTKLRDHIEEKHLHKTYKCQICLKTSKNRVNLDQHIRNVHKGRPNNKMCHHCGKGFPTKVQLESHIRTHTGERPFICEYCPTTFSQQSNLYKHNRQVHLNLKTKRYPIAKKRKDDKPPELTMVPAEIPLEYPVDIDFPI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00649381;
- 90% Identity
- -
- 80% Identity
- -