Efus005621.1
Basic Information
- Insect
- Ennomos fuscantarius
- Gene Symbol
- -
- Assembly
- GCA_905220475.1
- Location
- HG992049.1:1937513-1940131[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.0022 0.21 12.8 5.6 1 23 152 175 152 175 0.95 2 18 0.0004 0.038 15.1 1.5 1 23 184 207 184 207 0.96 3 18 0.0049 0.46 11.7 0.5 3 23 221 242 220 242 0.97 4 18 0.00046 0.044 15.0 0.8 1 23 251 274 251 274 0.96 5 18 0.00046 0.043 15.0 2.3 2 23 288 310 287 310 0.96 6 18 0.00011 0.01 17.0 0.7 2 23 342 364 341 364 0.97 7 18 0.001 0.097 13.9 1.5 2 23 374 396 373 396 0.96 8 18 0.017 1.6 10.0 1.7 2 20 401 419 400 421 0.90 9 18 0.0018 0.17 13.1 0.6 2 21 426 445 425 448 0.94 10 18 0.0034 0.32 12.2 0.5 3 23 458 479 457 479 0.96 11 18 0.016 1.5 10.1 3.7 1 23 484 507 484 507 0.93 12 18 0.00023 0.022 15.9 2.4 1 23 518 541 518 541 0.98 13 18 0.02 1.9 9.8 4.5 1 23 561 584 561 585 0.92 14 18 0.39 37 5.7 1.3 2 23 591 611 590 611 0.89 15 18 0.003 0.28 12.4 2.3 2 23 617 638 616 638 0.97 16 18 4.3 4e+02 2.5 2.1 3 23 646 668 644 668 0.90 17 18 0.009 0.84 10.9 0.2 1 23 704 726 704 726 0.97 18 18 0.17 16 6.9 2.0 1 23 732 755 732 755 0.96
Sequence Information
- Coding Sequence
- ATGTCACTTAAAACAGAACCTTCAATAAAGTCTGAGAAAGATGGGCGCAAAGATCCTACAAGCTTTCTACCTGAAGAAGAGATGTCATATGAAATAAAGAAGAAGAAAAAGAAAAAGAAGAAAAAACAAGAGGACCCATTTAAAGATATAGAAGAAAAGATGGCCATAGTAAGAGAACCAGACATAACTGCACTTGACCCGGATATTGGAATGAGTATGGACCCTGAAGTTACTATTAAGGTGGAAAATATTGAGGTGGACTTGGATTTTAATGATTTCATTCCCAATGATTTTGATCCACATGATGATGACTGCCCTCCAGAACCAATAGTCAAACTTGAAGAACAAAATAAAGATGCTATATTACTTACTTTCGAAAGCGTCATTAACGGCAAAACAATGTGTGTATCTAAGTCAGAAGAAGTTAATGAAGAAGGTGAACCAACCCCCAACCACTTCTGTAAAGTGTGCCATTTAGTCTTCAAAAGCCCTAAAACATTGTTGATGCATCAGAAACGTAAACACAAGCGCTTCAGACGCTTTTTCCAACACATATGTGATCATTGTGGCATGTCGTATGATGCTAAGAACAGTTTAGTAGCTCACATCCGACGAAAACATGGACCAGACGCCAAGAATGAAGATATGCAAGAAAAAGCATGTGATATTTGTGCGCTAGTCTTTAAAGGATTTAGCAGGCTTCGCATGCATATGCGTAGAAAGCATGGATCTTATGAAGACTCTTTCAAGCATGCTTGCGAAGACTGTGGGTTAACATATGATAAGTATGCAAGCTTAATCGTGCACAGAAGAAGGAAACATAGTAATGTTACTAAGCCAATGAACTTAAATCATTGGTTGTCATGTCCATTTTGTTCAAAGCTGTTTCGTAGAAGAGATACATACTCTCGTCATATTCAAAGAAAGCATCAAGTTGAAGAAGATGATGATATTAAGAAAGAAAATGCTGAATCAGATGAAATATTAAAGAATAGTGTTAAGAATGAAATGTCTGGAGAAGTTACTTGTTCTTACTGTCCTTTGATGTTTTCGTCCATAATGTACCTAAAGTTACACATGAGGAGAAAGCATAATGCTTTGACAAATGATTTTAGACTGAAATGTAAACTTTGTAACCTATCATATGATAAAGTAGAGAGTTTGAAGCGTCATGTGAGACGGAAGCATGATGCCGGGACATATTGTGAGGTATGCAGTAAGACTTTTACCTCCAGAGAAAAGTACTTAAGTCATTCACATACTAAAGTTGTTAAGGAATGTAGTCTTTGTGGACTTATATTCGCCAACCAAGGAGGTTTAGCGAAGCATTTGAGGTGTACACACAAGATGGTTGCAGATAAGACTGTGTTTTGTAATATTTGTAATGAAGGTTTTAATGATAAACGGCAGCTCAAACCACACTACATGAGAGTTCATTTAAAAGTTAGTTACACATGTAAATTTTGCAGTAAATTGTTTAAAGCAAAAGAGAGTTATAGACGCCACCTCATCTTTAAACATCCTGATAGTTATATTGACGAAAAGAAAACGCACCAGTGTGAGAAATGTCCAGAAATATTTATGAATGAATTTGAACTCTGCAAGCATATTAATACAATTCATCGAGACAGTGCAGATATTGTAATAAAAAAAGAAGAGAAAGACGTTATTAAAGATTTATTTAAATGTACTAAATGTACGGACGAATTTACTAGCTGGGAGCATTTGAGAGTGCATTTTGAGCAAACGCATCATTTGACTGAAGAGACCCAGTGTCAAAAGTGTGGAGAACTAATGCCTAGAAGTGATCTACAGAAGCACATAAAAGTGCATGAAGAATCAGAAATGACATGCAGATATTGTGAATTCAAGACTAAAAACAGAGTAAGTTTGACTCAACATATGCTCCGTCACACAAATGCAGAAACTATCCACTGTGACTTCAACGGGTGCAAATATAAAACTTTCTACGAAGATGCAATGGCCAAGCATAAAAGACGTCATGTAGATTTGGGAGTGAAACTTCAATGTGCAAGTTGCCCATTTCAGACCATGAACAAGTACATATTAAAATATCACGAAGAAGCGCATTCCACTGGTAAAAAGCGTTATTCTTGCGATAAATGTGATTATGCTACGATACTTCCCGCCAACTTGGTCCAACATAAGTACAAGCATGCCACAGAAAAGAGGTTTAAATGTGAAGTGTGCCCCTTTGCTACAAAATACAACACTTCTTTACGTTTTCATGTTAAAAAGAAACACTGTGATCTACCCACATTGAGGTAG
- Protein Sequence
- MSLKTEPSIKSEKDGRKDPTSFLPEEEMSYEIKKKKKKKKKKQEDPFKDIEEKMAIVREPDITALDPDIGMSMDPEVTIKVENIEVDLDFNDFIPNDFDPHDDDCPPEPIVKLEEQNKDAILLTFESVINGKTMCVSKSEEVNEEGEPTPNHFCKVCHLVFKSPKTLLMHQKRKHKRFRRFFQHICDHCGMSYDAKNSLVAHIRRKHGPDAKNEDMQEKACDICALVFKGFSRLRMHMRRKHGSYEDSFKHACEDCGLTYDKYASLIVHRRRKHSNVTKPMNLNHWLSCPFCSKLFRRRDTYSRHIQRKHQVEEDDDIKKENAESDEILKNSVKNEMSGEVTCSYCPLMFSSIMYLKLHMRRKHNALTNDFRLKCKLCNLSYDKVESLKRHVRRKHDAGTYCEVCSKTFTSREKYLSHSHTKVVKECSLCGLIFANQGGLAKHLRCTHKMVADKTVFCNICNEGFNDKRQLKPHYMRVHLKVSYTCKFCSKLFKAKESYRRHLIFKHPDSYIDEKKTHQCEKCPEIFMNEFELCKHINTIHRDSADIVIKKEEKDVIKDLFKCTKCTDEFTSWEHLRVHFEQTHHLTEETQCQKCGELMPRSDLQKHIKVHEESEMTCRYCEFKTKNRVSLTQHMLRHTNAETIHCDFNGCKYKTFYEDAMAKHKRRHVDLGVKLQCASCPFQTMNKYILKYHEEAHSTGKKRYSCDKCDYATILPANLVQHKYKHATEKRFKCEVCPFATKYNTSLRFHVKKKHCDLPTLR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00649377;
- 90% Identity
- iTF_00649377;
- 80% Identity
- -