Efus018250.1
Basic Information
- Insect
- Ennomos fuscantarius
- Gene Symbol
- Zfa
- Assembly
- GCA_905220475.1
- Location
- HG992048.1:9188098-9200126[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0017 0.16 13.2 0.7 1 23 287 309 287 309 0.99 2 11 0.25 23 6.4 0.3 1 23 316 338 316 338 0.97 3 11 0.9 85 4.6 0.3 1 20 342 361 342 365 0.74 4 11 4.2e-05 0.004 18.2 1.5 1 23 372 395 372 395 0.96 5 11 2.3e-05 0.0022 19.0 0.9 2 23 402 424 401 424 0.96 6 11 0.00019 0.018 16.2 2.8 1 23 437 459 437 459 0.95 7 11 9.5e-05 0.009 17.1 0.9 1 22 465 486 465 490 0.94 8 11 0.00039 0.036 15.2 1.5 3 23 500 521 498 521 0.95 9 11 2e-05 0.0019 19.3 1.1 1 23 527 550 527 550 0.97 10 11 6.4e-07 6.1e-05 24.0 0.4 1 23 559 581 559 581 0.99 11 11 0.016 1.5 10.1 0.2 1 19 587 605 587 610 0.92
Sequence Information
- Coding Sequence
- ATGGAAACGACTTTAGTAGAAGCTGCAGAAAATCTTCATTGTTTGGGATGTCTGTGTAGTTCAAAAGAATCCAGAATACAGGATTATAAAATTCAATATGCCCATTTCTTGGCGATGTTTGAGGTAACATCAATAAAATTATGTTATTTATGCAAGCGCATTGCCCATCATGCTGAGGTATTCATACAAAATGTACAGAGTAATCAGATATTATTGGAAAACTGTCTGGGCGATGTGTCTACTACCATAAAGGAAGCCCATTCACAACTGGAGCCACTTAAATGCCTCTCTCACACAACTTTAGATACCATCAGTTTAACGGGCAGTGACTTAACGGACTCAGTAATCAGTAATAGTTTTAAAACTTCCAAAACTCAGTTAAAAGATGGAGATATAAAACAATGTAACATCAGCGTGGATCGATTAAGTGTTAATGGGAGTAATGCTAAGTTGAAAGGTGGTATTGAAGAATTGTGTGGCAGAGAGCAAAATAAAGATATGATTAAAACTGAACTGAAAGAGGAAGACACATTAGATCATTTGGAAGGAGAAATAGTTGATGATGATGAATTCCAAGATTCATACTTTAAAGATGAAGATGATTTTCCTTTGAAAGCATTTTTAAAGAAAGAAATACAAATAGAGACTATTGAAAGGAGATTAAAAAGGTCTCTTCGAAAGAAGAAAGTGAAAAATAAGAGAAGCTTTGAAATAAAGGCGGAAATTGAAGAACCAGAGATTTTAGATAATAACGGTGCAACTAGCTTAACAGAAATAGAAACGATTCATATAACAGAAGAACAATGTATGGAGGAGAGGAAACAACTAGCGTTGGACGAGAAATATTTAAATCGTACATACAAGTGCTCTGATTGTATCAAAGGGTTTAATTTTAAAGCGAGTTATGTTGTGCATATGGAAAAACACAGTGAGGCTATGGGACAATTTGAATGTGACATATGTAAACTAAGAATGGACACTGAAGAGAAATTGGTCGGTCACAGAAGGTATCACACAATTCGGTACAAATGCACCGAGTGCGGTTTGATCCGCATCAGCCGGTTGACGATCAAGGATCATTACGACGCGTACCATAGACAAGGCGAGCGGCAGTACGCTTGTCCGTACTGTGCCAAATCTTTTAAACGCCAAGTGTCCCAGAGAAAGCACGTGAGGTATACGCACTTGAAGAAAGAGCGGGTAGTCTGTGGCTACTGTCACAAAAGCTATGCCAACAAGGATGTACTCAAGTCGCATATGATGTCAAGTCACCCCAAAGAAGTGTCGGCCAATGAGGCAGCGCGGCCGTTTGCGTGCGAGCAGTGCGGAATGACGTTCAAGGCTCGCTCGCACCTGAAGAACCATTCCACCAAGCATTCTGTGACGCGGGACTACTACTGCGTCGAGTGTGACAAAGCCTTCAAAACTGAGACAGTATTGAAGCATCATCTGAAAACGGCGCAGCCTCACGTCAACTATCTAGAACTACCATTGGCCTGCCAGCACTGCGACAGGAAGTTCGCCATAAGAAGAGATCTAGAGCGGCACACGAATAGAGTGCATTTGGATGTCAGACCCTATAGATGTGACAAATGCGATAAGGCGTATGTGACCAATTGGTCGCTCATCGACCACCGGCGCCACGTGCACGACGGTTACAAGCGACCCCTGCGGTACCCCTGCAAGATGTGCGACAAAGTATTCGACCGTAGTTCCATACTAAAGGCCCACATTCGCACCCACACGGGCGAGCGGCCCTACCAGTGCTCCAAGTGTCCGGCGCAGTTCACGCAGTCTGGCGTCCTGGCCACCCACGACAAGCTGATCCATCTCCGGCTAACGAGGGACGGGAGGCCGAAACCGGCCGGGAAATGA
- Protein Sequence
- METTLVEAAENLHCLGCLCSSKESRIQDYKIQYAHFLAMFEVTSIKLCYLCKRIAHHAEVFIQNVQSNQILLENCLGDVSTTIKEAHSQLEPLKCLSHTTLDTISLTGSDLTDSVISNSFKTSKTQLKDGDIKQCNISVDRLSVNGSNAKLKGGIEELCGREQNKDMIKTELKEEDTLDHLEGEIVDDDEFQDSYFKDEDDFPLKAFLKKEIQIETIERRLKRSLRKKKVKNKRSFEIKAEIEEPEILDNNGATSLTEIETIHITEEQCMEERKQLALDEKYLNRTYKCSDCIKGFNFKASYVVHMEKHSEAMGQFECDICKLRMDTEEKLVGHRRYHTIRYKCTECGLIRISRLTIKDHYDAYHRQGERQYACPYCAKSFKRQVSQRKHVRYTHLKKERVVCGYCHKSYANKDVLKSHMMSSHPKEVSANEAARPFACEQCGMTFKARSHLKNHSTKHSVTRDYYCVECDKAFKTETVLKHHLKTAQPHVNYLELPLACQHCDRKFAIRRDLERHTNRVHLDVRPYRCDKCDKAYVTNWSLIDHRRHVHDGYKRPLRYPCKMCDKVFDRSSILKAHIRTHTGERPYQCSKCPAQFTQSGVLATHDKLIHLRLTRDGRPKPAGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00649361;
- 90% Identity
- -
- 80% Identity
- -