Efus000216.1
Basic Information
- Insect
- Ennomos fuscantarius
- Gene Symbol
- -
- Assembly
- GCA_905220475.1
- Location
- HG992045.1:3620188-3622914[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.14 13 7.2 0.2 5 23 365 383 364 383 0.95 2 11 0.016 1.5 10.1 0.0 1 23 389 411 389 411 0.93 3 11 2.7e-08 2.6e-06 28.3 0.7 2 23 446 467 446 467 0.98 4 11 0.0019 0.18 13.1 4.2 1 23 473 495 473 495 0.99 5 11 0.043 4.1 8.8 0.4 2 19 500 517 499 519 0.94 6 11 3.1e-05 0.0029 18.7 0.1 1 23 549 572 549 572 0.97 7 11 0.0003 0.028 15.5 0.1 3 23 581 601 580 601 0.99 8 11 0.00094 0.088 14.0 2.0 1 23 610 632 610 632 0.98 9 11 3.6e-05 0.0034 18.4 3.9 1 23 638 660 638 660 0.98 10 11 0.0026 0.25 12.6 0.3 3 23 668 688 666 688 0.98 11 11 8.3e-05 0.0078 17.3 0.7 1 23 694 717 694 717 0.93
Sequence Information
- Coding Sequence
- ATGGAAAATTGGACAGACCTTTGCCGTTGTTGCTTGTCCGCCAATTCGAAGGTGTCACTTTTGGACAGCGAAAAAAATATCACGCGGAAGTTTCTTGAAATAACCAGTATTGAGGTCAAAGTTGATGACGGCTTACCTCAGAAACTGTGTGAAGAGTGCTACACAGCTATGAATTCAGCATACCAGTTCCGAAAACAATGTATCAAGATGGATACTGAGCTAAAAATCCAGCTTAACAACCTGATAAGCCAATGCAATGAAAGCAATATTGAAAACTTAGAAAATGCTGCAGGAACTGCTAATGTAAATAATGATGTAGAATTTGCAAACAATCCTATGAAGCAACTAGAGGCTGTTATAAAAAAAGAACCAATGGATAGTGATGATGACTATTATTATGTTCTAGTCATTGACAACCCAAAAGATAAGGAAAACTCTGATGAGCCAACAACAATCAACAAAATCAAGACTGAAACCCTGGACTCGCCAAATATCCAATTAGAAGAACAAGAAAATACAATGGAAAGCAATTGTCTACAAATTCAAGATATTTCCGAAACACAAGAAACAGATGAGCATCATGACAACCCAGAATCTATTGTACCTCATCTAAATCATGACTTTGAAGAAAACATGGACTCATTCTTAATAACTAACAACATACCAATGAATGTGCCAGCTACAATTTTAGAAAATGAAGAATGTCACTATGACAATATGGATGATGCTATGAACATAGATGAAACACAGGATAGCACATCTCAAGAACAACATTTACAAGGAGATGAGATCTCTGAAGATAATATAGTGCAAAAGATAACCAATCAGAACCTGATCAAAATATTAACAACTGCTAACTCGGATGGTACAATACTTTTGAATAGTGATGGGATGGTACAGTACTTAACGGATGGAGGACAGTTGGTGATGAATGATGAAGATGGAGAGCAGTCACAAGAAGTAATTTTGTGTGAAGGTGATGAATCACAATTTCAGATTGTGAAATATGATGGATCAGAATTGGTTATAGAATATGCAGATGACAGTGGAATAGCTACAGTTTTGCAGCAGACAGAGGATAGGTATTTGTGTGAATGTGGAGACCAGTTTAATGACTTGGATGAGTATGAAAAGCACCAGCAGAAACACAATCCAGCAGGTGACTACCTATGCAGTTTATGCGGCAAGGGATTTGAATCAAATGAGATACTGGCTGGCCACATGCTTCTTCATAATGAGTCGAGTACACTGCTAGAGTGCCCACTCTGCAAACAACTAATGAAAAGAAATGCATTGACTCAGCACATCAAATACGGACACAGTAATGTCAAGCCCAAATGTACTATCTGTGATAAAACATTTGCAAACCCCAATAACTTGAAACGCCACATGATGATACACACAGGAATAAAAGAATATGAATGTGACATCTGTTTCAAACGTTTTCATCAGAAAATCACAATGCAGACTCATAGGCTTACACACTTAAACCCGTTAAGTTGCTCTAAGTGTGATGTAGGGTTTAAAGACAAGGAGAGCTATGATAAGCATAATGAAGCTGGTTGCATACCTAAAACTTCAAAGGAAGAACTGATGCAATCAGTCAAGCAAGAAGTCACCACTAACCTCGGAAGGTTGTTGGGTTATGCTTGCTCTCTCTGTAAGAAAATGTTCTCGATAGAATCTGCATTGGAACGGCATATTGAAACCGTGCACATTGTAGATCCAGCTGAATTGTTATGCTCGGAATGTGGAGAAGTAGTTGCATCAAAGAAGGATATGCAAGCACATATTCAAACACATGACAAAGGTAAAACAGTCAAGCGTTTTGAATGTTATACGTGTGGTAAAGGCTGTTCCAGTCATGCAATGTTAATTATGCATGAAAGAGTACATACAAATGAAAGACCGTATGATTGTCAGCTTTGTCCTTTGAAATTCAAAACAAAGACACATTTACGTACTCATCAACTTACTCACACGAGGGAAAAGAAGTTTGGATGTTCGGTCTGCATGAAGTTCTTTGCCCTGAAAGGTAATTTGGTTGTCCATTTGCGTACCCATACAGGAGAACGGCCGTACATTTGTTCATTGTGCGGTGAAGCATTTATCGATTCTAAATACTTGAAGAAACATAAGGTGAAGAAGCACGCAATAGATAATGTTCCGTGGAATCAGTATTTACAGATCAAAAATGAGGATCATTACGTGGAAGAGGAAAATTAA
- Protein Sequence
- MENWTDLCRCCLSANSKVSLLDSEKNITRKFLEITSIEVKVDDGLPQKLCEECYTAMNSAYQFRKQCIKMDTELKIQLNNLISQCNESNIENLENAAGTANVNNDVEFANNPMKQLEAVIKKEPMDSDDDYYYVLVIDNPKDKENSDEPTTINKIKTETLDSPNIQLEEQENTMESNCLQIQDISETQETDEHHDNPESIVPHLNHDFEENMDSFLITNNIPMNVPATILENEECHYDNMDDAMNIDETQDSTSQEQHLQGDEISEDNIVQKITNQNLIKILTTANSDGTILLNSDGMVQYLTDGGQLVMNDEDGEQSQEVILCEGDESQFQIVKYDGSELVIEYADDSGIATVLQQTEDRYLCECGDQFNDLDEYEKHQQKHNPAGDYLCSLCGKGFESNEILAGHMLLHNESSTLLECPLCKQLMKRNALTQHIKYGHSNVKPKCTICDKTFANPNNLKRHMMIHTGIKEYECDICFKRFHQKITMQTHRLTHLNPLSCSKCDVGFKDKESYDKHNEAGCIPKTSKEELMQSVKQEVTTNLGRLLGYACSLCKKMFSIESALERHIETVHIVDPAELLCSECGEVVASKKDMQAHIQTHDKGKTVKRFECYTCGKGCSSHAMLIMHERVHTNERPYDCQLCPLKFKTKTHLRTHQLTHTREKKFGCSVCMKFFALKGNLVVHLRTHTGERPYICSLCGEAFIDSKYLKKHKVKKHAIDNVPWNQYLQIKNEDHYVEEEN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00649367;
- 90% Identity
- -
- 80% Identity
- -