Basic Information

Insect: Ennomos fuscantarius
Gene Symbol: Ctcfl
Assembly: GCA_905220475.1
Location: HG992023.1:15531843-15555448[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0032 0.3 12.3 5.3 1 23 177 199 177 199 0.98

2 11 7.6e-05 0.0071 17.4 1.3 1 23 205 227 205 227 0.98

3 11 4.7e-05 0.0045 18.1 2.0 1 23 233 256 233 256 0.95

4 11 0.01 0.96 10.7 3.3 1 21 262 282 262 284 0.95

5 11 0.00011 0.01 17.0 2.7 1 23 290 312 290 312 0.99

6 11 7.8e-06 0.00073 20.5 3.0 1 23 318 340 318 340 0.98

7 11 0.0052 0.49 11.6 0.5 1 23 348 371 348 371 0.96

8 11 0.0052 0.49 11.7 4.5 2 23 378 399 377 399 0.96

9 11 0.00033 0.031 15.4 2.1 1 23 405 427 405 427 0.99

10 11 2.8e-06 0.00026 22.0 1.3 1 23 433 456 433 456 0.95

11 11 6.8e-06 0.00064 20.7 4.8 1 23 470 492 470 492 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0032	0.3	12.3	5.3	1	23	177	199	177	199	0.98
2	11	7.6e-05	0.0071	17.4	1.3	1	23	205	227	205	227	0.98
3	11	4.7e-05	0.0045	18.1	2.0	1	23	233	256	233	256	0.95
4	11	0.01	0.96	10.7	3.3	1	21	262	282	262	284	0.95
5	11	0.00011	0.01	17.0	2.7	1	23	290	312	290	312	0.99
6	11	7.8e-06	0.00073	20.5	3.0	1	23	318	340	318	340	0.98
7	11	0.0052	0.49	11.6	0.5	1	23	348	371	348	371	0.96
8	11	0.0052	0.49	11.7	4.5	2	23	378	399	377	399	0.96
9	11	0.00033	0.031	15.4	2.1	1	23	405	427	405	427	0.99
10	11	2.8e-06	0.00026	22.0	1.3	1	23	433	456	433	456	0.95
11	11	6.8e-06	0.00064	20.7	4.8	1	23	470	492	470	492	0.97

Sequence Information

Coding Sequence: ATGGCGCCCATACGAAGGTCTTACCGAAATACAAAGCATGTTATGCACCCTGCTATTCCAGAAGAACCTGCAGAACCCGCTGAGGAGGAAATCGATACTGGTGGGGTCACTTACTTTGTAGATGAGGAAGGACGATATTACTACCAACCCGGGCAGAACCTTGTATCTTTGCCAACCAGCGATGAAAATACTATGGTGCAGTTATGTGAATCGCAAGAACCAGTCCAGATAGAAGAGGCAGCTACCCAGAAAGGCGAATCAATTGAAGCTGAAGCATATCAGACTGTGACATTGGTGCCATCGAAGAATAGTAATGGGGAAGTGAGCTATGTTCTAGTGGTGCAAGAAGAAACACAACCAATCATCAACGTTGACAATATTAAGGAAGAGAAGCCCGTTGTAGATGTGTACAATTTCGAGGATGAAGAAGAAGAGGGAGAAGAAGAAGAGGAGTCAGTACATGATGAACCATCAAATTCTCCTACTCGCGCAAAGAAGAAACGCAAAGGCAAGGGCTCTCGCGCAAGCTTCACTTGCAACTTCTGCTCTTACAGCAGTCACAGGCGGTATTTGCTAGTCCGACACATGAAATCGCACTCCGAGGACCGTCCACATAAGTGCGAAGTCTGCGAGAGGGGTTTCAAGACGATTGCTTCGCTTCAAAACCATACCAACATGCACAATGGAGTTAAACCTCATAACTGCAAGTACTGCGAAGCTACATTCACTACAAGCGGCGAGTTGGTGCGTCACGTCCGCTACAAGCATACTCACGAGAAGCCGCACAAGTGTACCGAATGCGACTACGCGTCCGTTGAGCTGTCGAAGCTCCGCCGCCATATTCGTTGCCACACCGGTGAAAGACCTTACCAGTGCCCTCACTGCACCTATGCATCTCCAGACACGTTCAAGCTGAAACGTCATCTCCGCACACACACTGGAGAAAAACCATACAAATGTGACATGTGTAACATGTGCTTCACTCAATCCAACTCGTTGAAGGCTCACCGATTGATCCACAATGTGTCAGAGAAGCCAGTGTACGCTTGTGAGCTATGTCCAGCCAAGTGTGGCCGTAAGACGGACCTGCGTATTCACGTCCAAAAACTGCACACGTCGGAAAAACCACTTAAATGCAAGCGCTGTGGAAAATCTTTCCCGGATCGATACTCATGCAAAGTGCATAACAAGACTCATGAGGGCGAGAAATGCTACAAATGCGACTTGTGCCCTTATGCTTCTACTACCCTGCGGCACCTGAAGTCTCATCTGCTGAAACACACCGATGAAAAACCTTTTGCTTGCGATGAATGCGACCAGTCCTTCAGACAGAAGCAACTGCTTCGCCGTCACCAGAACTTGTACCACAACCCGGATTATGTACCTAAGCCGCCAAAAGAGAAAACGCACACGTGTCACGAGTGTAAGCGCACATTCGCCCACAAGGGAAACCTTATCCGTCACTTAGCGGTTCACGACCCGGAATCGGGTCACAAGGAACGGGCGCTCGCCCTCAAGCTTGGAAGGCAGAAGAAGATCAAATACATTGATGCTGAGACTCTAAAGGTACTCCAAGAAGAAGGCCGCAGCAGCAGCAAGACTCAAGTCCTCAAGATCGGCGTTTCTTCAGAACTGAAGCGAGGCGAGCTGGTCACTGTGAACGATGGTGACGGCCAACAGTATGTGGTGTTGGAAGTCATACAGTTGGAAGATGGCACGGAACAGCAGGTGGCGGTCGTCGCGCCTGAATACCTCACCATGAGGCATAAAGAAGGTTCAGATATGGTGATTGAAGTGGAAGACGAAGAAGGAGACGATGCAGAAGACGAGGATATAGATGAAACTGCCAATGAGGAACTGGAAATGGAGGTGGAAGTACAAGAAGATGAAGAGGAGGAGGAGGAGGAAGAGGAAGAAGAAGAAGAAGAGGAAGATATGCAAGCTAAAATGCAAAAGCACATACTGAACCAAGAGAAAGCTGCCGTGGAGCGTTCCATTAAACTTGAGAAGGATGTGGGAGAATGCTTCGGCTTTGAGGAGGAAGAAATTGAAGGTGATGAAGTTTACCCAGAAAACGTGATTTATCAGCTGGTTTAA
Protein Sequence: MAPIRRSYRNTKHVMHPAIPEEPAEPAEEEIDTGGVTYFVDEEGRYYYQPGQNLVSLPTSDENTMVQLCESQEPVQIEEAATQKGESIEAEAYQTVTLVPSKNSNGEVSYVLVVQEETQPIINVDNIKEEKPVVDVYNFEDEEEEGEEEEESVHDEPSNSPTRAKKKRKGKGSRASFTCNFCSYSSHRRYLLVRHMKSHSEDRPHKCEVCERGFKTIASLQNHTNMHNGVKPHNCKYCEATFTTSGELVRHVRYKHTHEKPHKCTECDYASVELSKLRRHIRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYKCDMCNMCFTQSNSLKAHRLIHNVSEKPVYACELCPAKCGRKTDLRIHVQKLHTSEKPLKCKRCGKSFPDRYSCKVHNKTHEGEKCYKCDLCPYASTTLRHLKSHLLKHTDEKPFACDECDQSFRQKQLLRRHQNLYHNPDYVPKPPKEKTHTCHECKRTFAHKGNLIRHLAVHDPESGHKERALALKLGRQKKIKYIDAETLKVLQEEGRSSSKTQVLKIGVSSELKRGELVTVNDGDGQQYVVLEVIQLEDGTEQQVAVVAPEYLTMRHKEGSDMVIEVEDEEGDDAEDEDIDETANEELEMEVEVQEDEEEEEEEEEEEEEEEDMQAKMQKHILNQEKAAVERSIKLEKDVGECFGFEEEEIEGDEVYPENVIYQLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00649366;
90% Identity: iTF_00649366;
80% Identity: -