Basic Information

Insect: Ennomos fuscantarius
Gene Symbol: Bcl11b
Assembly: GCA_905220475.1
Location: HG992023.1:9367086-9379333[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.67 63 5.0 2.2 1 21 163 183 163 184 0.94

2 12 0.019 1.8 9.9 0.2 2 20 198 216 197 218 0.96

3 12 0.0023 0.22 12.8 4.7 1 23 259 281 259 281 0.97

4 12 0.37 35 5.8 0.1 2 20 383 401 382 403 0.87

5 12 0.00022 0.02 16.0 1.9 1 23 411 434 411 434 0.97

6 12 7.3e-05 0.0068 17.5 1.8 1 23 457 479 457 479 0.98

7 12 9.8e-06 0.00092 20.2 3.9 1 23 486 508 486 508 0.98

8 12 4e-07 3.7e-05 24.6 1.8 3 23 522 542 520 542 0.96

9 12 4.7e-06 0.00044 21.2 0.6 1 23 548 570 548 570 0.99

10 12 4e-07 3.8e-05 24.6 2.5 2 23 577 598 576 598 0.96

11 12 1.3e-07 1.3e-05 26.1 1.5 1 23 604 626 604 626 0.99

12 12 5e-05 0.0047 18.0 0.1 1 23 632 654 632 654 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.67	63	5.0	2.2	1	21	163	183	163	184	0.94
2	12	0.019	1.8	9.9	0.2	2	20	198	216	197	218	0.96
3	12	0.0023	0.22	12.8	4.7	1	23	259	281	259	281	0.97
4	12	0.37	35	5.8	0.1	2	20	383	401	382	403	0.87
5	12	0.00022	0.02	16.0	1.9	1	23	411	434	411	434	0.97
6	12	7.3e-05	0.0068	17.5	1.8	1	23	457	479	457	479	0.98
7	12	9.8e-06	0.00092	20.2	3.9	1	23	486	508	486	508	0.98
8	12	4e-07	3.7e-05	24.6	1.8	3	23	522	542	520	542	0.96
9	12	4.7e-06	0.00044	21.2	0.6	1	23	548	570	548	570	0.99
10	12	4e-07	3.8e-05	24.6	2.5	2	23	577	598	576	598	0.96
11	12	1.3e-07	1.3e-05	26.1	1.5	1	23	604	626	604	626	0.99
12	12	5e-05	0.0047	18.0	0.1	1	23	632	654	632	654	0.98

Sequence Information

Coding Sequence: ATGGACTCTCACCACAAAATTGAAATAAAAATTGAAAAGTTGTGTCGTACTTGTTTGTCGAGAGATAATGAATTAAATTCCCTGTTTGATGTAACTGTCGGAACAGTTTCACTGGACTTCGTAGTTACCGCTATCACTGGATTAAAGATTCGCAAAGGAGATGGACTGCCATCAACAATATGCTGCGAATGTAAGGACAAGGCTGAAAAGGCATATGATTTTAAAAAGAAATCTCAGGAAGCACATATTTCACTTAGAGGTTTTTTCAAGAAAGAAACAAAAGTATTGAAAAAAATAGAAGATGTCAATGTTGTTGAGAACAAGTCAATGGGTGTTAAAACTGAACAATCTAATTTTAATGATATCACTGATGATTTTTCTGATGCTGACTACAGCTTCCCCCTGAGTAACAATCCGGATGAATCAAATAATTTTGAGATTGCCGTGAAACACGAGAAAGCTGATAAAGAAGAAAAAGTGTTATTCTTTGAATGTAAAATGTGTTGTCTAGTATTTGAAACTGCTACCCAGTATCAAGAACATAAAAAAAAGAAATGTGTTAAAGTTGAATATGAAGGTGTGAACGGAACATACTGCCCTATTTGCGGAACGTGCTATGATGGAGACAACAGTCTATCTAAGCACATGTGGGAGTTTCACGCTGATTTAATGGGGCCAAAAAAAAGAGGACGCCCCAAGAAACTAATGACTACGACAATTTTAAATAAGTTATCAGAAAATGGTTTACTGATTTCGTCAACACAAGGAAAGACTTACCAATGTTCATTTTGTAAGAAACATACCAAAACTAGAGAAGATCTTAGTATTCACATGTTTCAACATAAAGATATAAAAGCATTATGTTGCATAATGTGTAAGAAAATTTTCATGAAGAAAAAGTTTTTTAACTCTCATTTGTGTGTTGGCAAAAATGCTTCAATCACTGATAATGATTCAAATACCAAAGTGGATAAAAATAGTAAAATGTCTTTCGCGACTGAACTACATCTGCAGGAGCTGCTTGACCCGAATGGTGATATGACGTTGACTAATATTATCCAAGTATGCACTGCGTGTAGCGGCGTTTACCTCTCTGAAGCGGATCTCATAAACCATCACGATACCGATCACCCAGAGCTTTCACTAAGATGTAATCATTGCTCCAAGTTGTTTGCCTCTATAGGGACTGCGGCGCGTCATAGAGTAGTTTGCAAGCAAATAGAGAGGATGCACAAATGTACGACTTGCGGTCTGAAGTTTGCATACGAAATATCGCTTAACAAGCACATACTCAGGTACCACCAGGGTCAAAGCGTATCGGTTGCATTTTTAAGTCGAAAAGCTGCAAAGGCAAATGAAAATGTGCAGTATCAATGTGATACTTGCCAAAAAATATTCCATAGAAAAGAAGCTCTTGCAAAACACGCAAAGTTGCACATGCCTAATCAGAAACTTTATGAATGCGACATCTGCCATAGGAAGTTCAATCGCACTGACAATCTGCGAACTCATAAGAAGATACACGACGTGGACCGCGCCAAGCCGCCGGCTAACAACTGCCTGTGTCTATACTGCGGCCGTGGATTCACTAACTCTTCCAATCTGATCGTGCACATGCGTCGGCATACTGGTGAAAAGCCGTACAAGTGCGATTTTTGTGCGAAAGGTTTTCCAAGATCGTCAGATCTCATGGTTCATAGAAGATCACATACGGGCGAAAAACCTTGCGTCTGTCGTATTTGTGGAAAAGCATTTTCTCGTAGCAACAAGCTGTCGCGACATATGCGCGTGCACACCGGTCAAAGGCCATACAAGTGCACCTATTGTGAGAAAGCGTTCTCTCAGAGCAACGATCTCACCTTGCATATTCGACGTCACACTGGCGACAAACCATACGTCTGTGAGGTGTGCGGCGAGAGATTCATTCAGGGTACAGCGCTACAGAACCACCGGCGAGCTCACGGCCATTTCCCACCCCCGCCGCCTGATCTGGCTAACCTCACGAACCAGGTTCAGGCTATCACTTACTCACCCCACGTCGCCAACATGAACCTCCAACATGAAACTCACATGCCCAACTAA
Protein Sequence: MDSHHKIEIKIEKLCRTCLSRDNELNSLFDVTVGTVSLDFVVTAITGLKIRKGDGLPSTICCECKDKAEKAYDFKKKSQEAHISLRGFFKKETKVLKKIEDVNVVENKSMGVKTEQSNFNDITDDFSDADYSFPLSNNPDESNNFEIAVKHEKADKEEKVLFFECKMCCLVFETATQYQEHKKKKCVKVEYEGVNGTYCPICGTCYDGDNSLSKHMWEFHADLMGPKKRGRPKKLMTTTILNKLSENGLLISSTQGKTYQCSFCKKHTKTREDLSIHMFQHKDIKALCCIMCKKIFMKKKFFNSHLCVGKNASITDNDSNTKVDKNSKMSFATELHLQELLDPNGDMTLTNIIQVCTACSGVYLSEADLINHHDTDHPELSLRCNHCSKLFASIGTAARHRVVCKQIERMHKCTTCGLKFAYEISLNKHILRYHQGQSVSVAFLSRKAAKANENVQYQCDTCQKIFHRKEALAKHAKLHMPNQKLYECDICHRKFNRTDNLRTHKKIHDVDRAKPPANNCLCLYCGRGFTNSSNLIVHMRRHTGEKPYKCDFCAKGFPRSSDLMVHRRSHTGEKPCVCRICGKAFSRSNKLSRHMRVHTGQRPYKCTYCEKAFSQSNDLTLHIRRHTGDKPYVCEVCGERFIQGTALQNHRRAHGHFPPPPPDLANLTNQVQAITYSPHVANMNLQHETHMPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00044719;
90% Identity: -
80% Identity: -