Efus012647.1
Basic Information
- Insect
- Ennomos fuscantarius
- Gene Symbol
- -
- Assembly
- GCA_905220475.1
- Location
- HG992051.1:5233222-5235980[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.00016 0.015 16.4 0.6 1 23 141 163 141 163 0.98 2 17 2.8e-05 0.0026 18.8 0.5 2 23 168 190 167 190 0.94 3 17 0.011 1 10.7 1.2 2 23 199 221 198 221 0.93 4 17 0.00037 0.035 15.3 3.4 1 23 226 249 226 249 0.96 5 17 0.82 77 4.7 2.5 1 23 255 278 255 278 0.95 6 17 1.6e-05 0.0016 19.5 0.2 1 23 284 306 284 306 0.97 7 17 4.2e-06 0.00039 21.4 2.9 1 23 312 334 312 334 0.98 8 17 2.6 2.4e+02 3.2 0.4 3 23 400 420 398 420 0.96 9 17 0.2 19 6.7 0.0 2 23 444 466 443 466 0.94 10 17 6.8e-05 0.0064 17.6 0.5 2 23 488 509 487 509 0.96 11 17 1.2e-05 0.0011 20.0 1.3 1 23 513 536 513 536 0.91 12 17 0.0074 0.7 11.2 1.0 1 23 543 566 543 566 0.94 13 17 0.14 13 7.2 2.5 1 23 571 594 571 594 0.94 14 17 0.0033 0.31 12.3 0.5 1 23 600 623 600 623 0.97 15 17 8.2e-05 0.0077 17.3 0.4 1 23 629 651 629 651 0.95 16 17 2.8e-06 0.00027 21.9 1.4 1 23 657 679 657 679 0.98 17 17 0.0013 0.12 13.6 7.4 1 23 685 707 685 708 0.96
Sequence Information
- Coding Sequence
- ATGCGGTCGATCCATTGGAAAGATTTATGGCAACGGCCCGCCACGTTCACAGTAAAATGGAGGCCCGTGCGCAAGTATAACGACGAGAGAGACAATGCGGCTATTATTCTAGAAAGTTCCAATGTTTGCCCGTTCAAATGGAAACAGGGTACATTCTGTTGTTCGTACTGCACATTTGTCTCAGCTGATTTCGGTCCTATTAGAGAACATGTCACTGACCATCCGAACAAGGTTGAAGCCTTACGCCTAGCGAGAGGTTCCACAATCAAGGCTGATGTTACTGATTTAAAATGTGAGCTCTGCCTTGGGAACATTAAAGATATACCGACATTGGTGGATCACCTAATCGAAGTGCACTGTAAACCTCTTAATAAGAAATACAGTCCCGGTATTGTACCTTTCATTCTCAACGAGGATGTGTTTAAATGCTCTGTATGTGACCTCACATTTGATCTGTTCGTTAATTTAAACAAACATTTAAATGAACATTACCCTAATAGCGTATGTTCATTATGCGGAAAATCTTTTTCACAATTGACTAGACTGAAAGCACATATACTTTACACGCATGAAAAAGAAAGACAGATGCGGTGCGCATGCACGAAATGCGGTGAAATATTCACCAATATACCCGATAAAAATAAACATATGGTGTCTAAACACGGAGTTCTGAAACATAGGTGCCCCTATTGCAATGAGTCTTTCAAATCATACCCAAGCAGAATGAAACATATGAAGGAATATCACGACAAAAAAATAGAATATCGTTGCAACATGTGCTCGGCTGTATTCCTACTATGCAGTCAAAGAACTAAGCACATAAAACAAGTGCATATCAAAGATAAACGATTCGCATGCACGGTATGTCCTTTTCGCTTCGTCACAGCTGCATCGTTGAGAAATCACATGATAAAGCATGGTGGCGAGAGGAAGCACCAATGTCAAGTTTGCAAAAAAGCTTACGCGAGGAAGAAGACGTTGAAAGAACACATGCGGATACATAACAACGATAAGAGGTTTATTTGTACACATTGCAATAGCGCAAAAGTGACGCACTTTTTTTTGGTTTTAGGAGCCAGTTTGATTAAGTGGACCCGAAAATATGAAGGCGGTAAATACGACGCGCGAGACAATGCAGCCGTTATCCTAGAATGTTCCAACGTGTGCCCTTTTAAATGGCGTAGAAATGTTTTCGGTTGCTCATTCTGTCCCCTCACTTCCATAGATTTCAAACAAATAAGAATACATTACAAAGAACACCCGGATAAACATAAAGCTCTGAGCAAGACGCGTGTTGCTGTAAATTCAATGGCAGACGTTTCTGATTTGAAATGTGAAATATGTAACGAAAACATGAAAGATATTGCATCCCTGTTTGATCATCTAATTGTAATACACAATAAGAACATGAATAGAAAATATGGTCCAGGCATTATGCCATTTCTCTTAACAAATGCAACCACATGTGCCGATTGTGGCCTAAATTTCGATAGCTTTACTCAATTGAATAGACACATGAATGAACACTATCCCAATTTTGTCTGTTCGCAATGCGGAAAGCCATTTTCCGACGAATCAAAGCTGAAAAACCATTACACGTTTTCACATGATAAGCAACCAAAGCAGTACAAGTGCCCGAAATGCGACGAATATTTCCCTACAACTTACGGCGTGGACAAACACAAAATGCAAAAGCATGGCATAGCCAAACACAAATGTCCGTATTGCAGCGAAATGTTTATGCAGTATCCGCGAAGATTGGAGCATATGAACAAGTATCACGGAACGAAGGTGGAGTTTCCGTGCAGTTTGTGTCCAAAAATTTTAAAGACTCACGGAGAGAGAACGAGGCATGTGCGAGTGATACACATAAAAGAAAAAAAGTATTTGTGTACAATATGCAGCAATATGTTTGTGGACTCCAGTCAGTTAAAAGAGCACATGGTGAAACACGGGGGAGAGAAGAAATACAAATGTCAATTGTGTAACAAAGCGTACGCGAGAAGAAAAACATTGAGGGATCATATGCGTGGACATAATAACGATAGAAGATTCGTTTGTACACATTGTAATAGTGCGTTTGTGCAAAAATGCAGTTTAACGAGCCATTTGAAGACGCATCATCTTAACACTGACTTAGATAAAACTACATGA
- Protein Sequence
- MRSIHWKDLWQRPATFTVKWRPVRKYNDERDNAAIILESSNVCPFKWKQGTFCCSYCTFVSADFGPIREHVTDHPNKVEALRLARGSTIKADVTDLKCELCLGNIKDIPTLVDHLIEVHCKPLNKKYSPGIVPFILNEDVFKCSVCDLTFDLFVNLNKHLNEHYPNSVCSLCGKSFSQLTRLKAHILYTHEKERQMRCACTKCGEIFTNIPDKNKHMVSKHGVLKHRCPYCNESFKSYPSRMKHMKEYHDKKIEYRCNMCSAVFLLCSQRTKHIKQVHIKDKRFACTVCPFRFVTAASLRNHMIKHGGERKHQCQVCKKAYARKKTLKEHMRIHNNDKRFICTHCNSAKVTHFFLVLGASLIKWTRKYEGGKYDARDNAAVILECSNVCPFKWRRNVFGCSFCPLTSIDFKQIRIHYKEHPDKHKALSKTRVAVNSMADVSDLKCEICNENMKDIASLFDHLIVIHNKNMNRKYGPGIMPFLLTNATTCADCGLNFDSFTQLNRHMNEHYPNFVCSQCGKPFSDESKLKNHYTFSHDKQPKQYKCPKCDEYFPTTYGVDKHKMQKHGIAKHKCPYCSEMFMQYPRRLEHMNKYHGTKVEFPCSLCPKILKTHGERTRHVRVIHIKEKKYLCTICSNMFVDSSQLKEHMVKHGGEKKYKCQLCNKAYARRKTLRDHMRGHNNDRRFVCTHCNSAFVQKCSLTSHLKTHHLNTDLDKTT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -