Efus012161.1
Basic Information
- Insect
- Ennomos fuscantarius
- Gene Symbol
- ZFY
- Assembly
- GCA_905220475.1
- Location
- HG992051.1:462768-470403[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 29 0.00046 0.043 15.0 2.8 2 21 164 183 163 184 0.94 2 29 0.089 8.4 7.8 0.5 1 23 217 240 217 240 0.96 3 29 0.018 1.7 10.0 4.4 2 23 246 267 245 267 0.95 4 29 0.21 20 6.6 5.6 3 22 272 291 271 291 0.94 5 29 0.0098 0.92 10.8 0.8 2 23 330 352 329 352 0.95 6 29 5.6 5.3e+02 2.1 1.3 4 21 361 377 359 379 0.80 7 29 0.0029 0.27 12.5 1.1 1 23 384 406 384 406 0.98 8 29 0.004 0.38 12.0 0.5 1 23 412 435 412 435 0.96 9 29 0.0015 0.14 13.3 0.9 1 23 444 467 444 467 0.97 10 29 0.00018 0.017 16.2 2.4 2 21 579 598 578 599 0.94 11 29 0.63 60 5.1 0.3 3 23 605 625 604 625 0.92 12 29 3.4 3.2e+02 2.8 1.6 3 23 632 653 631 653 0.87 13 29 0.012 1.1 10.5 0.1 2 23 659 680 658 680 0.94 14 29 1.6 1.5e+02 3.8 1.6 5 20 686 701 684 703 0.90 15 29 0.004 0.38 12.0 1.0 1 23 716 739 716 739 0.93 16 29 6.9e-05 0.0065 17.6 2.6 1 23 745 767 745 767 0.98 17 29 0.012 1.1 10.5 0.7 5 23 777 795 775 795 0.97 18 29 0.87 82 4.7 0.5 1 23 801 824 801 824 0.86 19 29 0.00054 0.051 14.8 0.6 1 23 832 855 832 855 0.94 20 29 0.00023 0.021 15.9 1.0 2 21 964 983 963 984 0.93 21 29 1.5 1.4e+02 3.9 0.0 3 23 991 1012 989 1012 0.90 22 29 1.8 1.7e+02 3.7 0.1 2 23 1018 1040 1017 1040 0.92 23 29 9.7e-06 0.00092 20.2 2.2 1 23 1045 1067 1045 1067 0.98 24 29 1.3 1.2e+02 4.1 3.3 2 21 1071 1090 1071 1091 0.93 25 29 4.8e-05 0.0046 18.0 0.6 1 23 1117 1140 1117 1140 0.95 26 29 0.0011 0.1 13.8 0.2 1 23 1146 1168 1146 1168 0.95 27 29 0.1 9.8 7.6 0.1 1 23 1174 1196 1174 1196 0.97 28 29 0.023 2.2 9.6 1.0 1 23 1202 1225 1202 1225 0.94 29 29 9e-05 0.0085 17.2 0.1 2 23 1232 1254 1231 1254 0.95
Sequence Information
- Coding Sequence
- ATGAGCCGCCATGTGGATGTGAAAGCACTCGTGTCGCATATCGTCAAAGGAGATGGGTTGGACAAATGCCGAATATGTATGGGCGACACATCACAAGGGCAAGTTCACCTCGAAGACACGGTGATGATGAACGGAGAACAGCCCGTCACACTCTCTGAGCTTCTCGAAGTGATCACAGGAGTCGAGGTGGTGATAGAAGATGCCCTGCCCTCAGCAATATGCATAGCATGCTCATCATCAGTTATCGAGGCAGCTGGCTTCCGTACCCTTGTACAAAATGCTGACCATCAATGGACCAACATGCTGCAACTTCTGGAACGTATACCAAAGTACAAGTATTCTAGAACAAGTGACAAAATTAGTGCTCTCCTCGGCAACAATGATATTTTTGTATATGATGAATGCACTAAGCCTGGAATGTTAAATAAAAAAAGTTTTGTAATTGAAGAAAATTTCCCTATGAAAAGATTGGGCAAACAGCATGATTGTGTGTGCCCGACATGTGGAAAGAAGTTTTCGTACTCACTTCATTTGTATAAACATTTAAAGGAGTCTGCGGATCTAATAAGAGCATGTCATATTTGTGCTGAGATCATGAACAGAGATGAGTTGGTACAACATTTGAATGTATATCATGAATTAAAACCGTATAGTTGTAAAAAATGCCCTGCAATGTTCTTAAATGGTGGACAGTACAGAAAGCACTTGCTTAAAGCACATACCTCAGGGTCTTGCACCTGCGGTGACTGCGGATGTAGCTTCCAGTCCAAACCAGCATTTCATGCTCATCAGTCAGTGCATACAATCCGCTGTTGTCCGAATTGTGACACCCAATTCCGTAACCAAGCTTGCTATTTTCATCATGTCAAGACATGCTGCAATATGGACCCATCGAACACGCAGAAATCTAAAATTACCGTAACTCTGCAAAAGAAGCAGAATCTGAAAGTGAAAATGGGCCTACGGGGCAGTGCTAATAAAGAATGCATTTGTGATTACTGCAAAAAAAAGTTTGCAGGAAAGAAATTTGTTGCAGCTCATATCCAAATCGTACATATGAAAAACACCCACAGGCCGTGCATATACTGTGGAAAGGTATTTGCAGCGGCTCACATGACTACGCATTTAAAATGTCACAATCAACCGAGTTTTGAGTGCCATCAGTGTGGAGCAGTACTTAAATCCAAGCTTGGTTTCAATCAGCATTTGAGATTACACACCGGAGAACGGCCATACTCCTGTCAGTATTGCGGAGAAGCATTCTCAGCATCATCAAGACGCTCAGAGCATATACGCAATACTCATAAAAAGTCTGAAATAGTTTTAAAACATGTTTGTGACCAATGTCCGGCACGGTTCAGGCTTCCGAATAAATTAAAGCAGCATGTGAAGACAGTACATGAGCAACATGGTGATGAACCGTGGTATGAATGCGGTGTAGAGGAGGATGAAACACTGCCCGCGTGCCTTTGCCACCGTTGCTCCGAAGCCGTCATTAGCGCAGCAGGCTTCAAGAAATTTTGCCAGCAATCGGCGCAATGCTGGACCGAAGCCACCGTTTATTTAACAACCACGCCCAATCCAACAGACTTGGATAAGACATTTTTCATATTCTGCAACAAAGGTGGAGCTATATTTAACAGTCCTGACGCAGTGACCGCGTTAGAAAACGCTGTGACGTTCTTGAATGGACCGAAAAAGAAGGAAAAGAAGAAAATAAAGCGCCAGTGTTGTGTTTGTCCGCATTGCAGTAAGCGTTTTAGTACTCTAGTAAATCTGAACGAACATCTGAAATTTATGCAAGAGAGATTCTGTTATGAATGCAGCGTCGTTGTCAATAAAAAGAATCTGGCGAAGCATTTGTTGGTCAAACATAATAAACAGGTCGTGGACTGCGCAAGTTGCCATAAACTTTTTAAGAATTCGACTGATGCCGAATCGCATTGGTTTCAGAATCATGGTGCGAATACACAACCATGTAATATTTGCGGAAGCGGATTTCCAAACGAACGCGGTCTTAGAGCCCATTACTTCCTGCACAACCTCTTCCACTGCATTTGTGGTGAAAGCTTCGAGAACAGCCGATGCTATAACTACCATCTAACTAAATGCAAGCCAAAGAAGCGTAGTTCAGTCGACTTGATCTTCGAATGCGATCACTGCGGAGTACAATACGACAAAAAACCATCTTTACGTACTCATATAGTCCAAAAACATCTGAATGTGCTTCCGTTTGTGTGCCAAACTTGCGGGAAGCGAACTTCCACGCTTGCACATTTAAGATCTCACGAGAAAACACACGAAAAAGAACGAAAGCTTTTGGAATGTTATTGCGGGGCCAAGTTCCGCTCCAAGTTAGGGTTTAAGCTTCACATGAGAATCCATTCGGGGGATAAACCTTACAAGTGTGAATTATGCGAAGAGAGCTTCCTCTCGGCGTCCCGGAGGCTGGACCACGTGAAGAGGCGGCACCAGAACTCGACGGACATGCCACACAGCTGCGAATCCTGCGGAGCGAAGTTTATAAGACCGTGGGAGCTGAAGAAACATTACCTGAACGTCCATAGTTCAATAGAGGAAGGTACTGAATGCCCGTCTGGAGTTTGCGTGACGTGCGCAAGCGCCGCCCTCGCCGCACAAGAGTTCCGCATATTGGTCAGGAGCTCCGAGAAGCTGTGGCTGAAAGCTATCTCGAACTTGACAAGCTTGCAGTATGACGATGAGACCGAACAGGCCAGGTCGATCTGCGCGTTTGTTACCCAAAACGATCTCAACGTACAGACCAGTAAAGATTACATCGGAGGTGAACCTAAGACAGTCGTCAACCGATTAAAAAGAAAAAGTAAAACTACCCGCAAACCTAGACTCGTCAGACCTGGCCCGACCAGCAAATGCCCAGATTGCAATAAAATCTTCACCAGTCCGTATTACCTACATGATCATTTCAAAAACAACGGTCAGAAGGACGCTTGTCAAATATGTGGTACGGTCACAGCCCGAGGACTTGCTATGTGGGACCACATGATATATGTTCACAATGAAAACCCGTCGATGTGCCAGCAGTGTCCTGCGGTATTCCTTAAAGAAGGCGATCTGGTTAATCATCGGAACGAAGCGCACAAACCTGGGGTTTATACTTGTATGGAATGTGGCAGATCGTTTCCAAGGAAGTCGACGTTTGAACATCACGCTCAAATGCATTTGGTACGGACGTGTCGCAGCTGCAACGTACAATTCACCAATAGAAGCTGCTACAGGGAACACAGGAACCAATGCGAGCCTAACGCAAAACCTGACAGCAAGACTGTGCCCCGCAACCGACGATCGAACATTCGAGATCCCGCTGTTTTTATATGCGATTACTGCAACAAAAAGTATAACTCGAGACCTCAGTTGAAAAACCATATATTGTGGATTCACATGGATGTTAGACCTTATCAGTGCCAATGGTGCGGAAAGAGGTTTTACACTCCCGCAAGAATGGCGGAGCACACGGTGGTGCATACGCGCGCGCGCAATTTCGAATGTGACATTTGTGGCGCGAAACTAGTTTCCAAAATGGCGGCGGTGTACCATAGACGACGCCATACGGGCGAGAAACCTTACAAATGCGATGATTGCCAGGCTACTTTTATTTCCTCATCTCGTAGGTTAGAGCACGCTAAAAGGAAGCATAACAAAGGCACTAGAATACCATGTCCTCTTTGCTCGGCTACTTTCGTTCGGAAAGCTGAGCTCAAAAAGCATATAGATAAAGTTCATAATACGGAAAGTAAAAGCGAGGGTACTATACAGACACATGAGTGGAAAGTAACGGTGCCACCAAGTATAGAAAGTTAA
- Protein Sequence
- MSRHVDVKALVSHIVKGDGLDKCRICMGDTSQGQVHLEDTVMMNGEQPVTLSELLEVITGVEVVIEDALPSAICIACSSSVIEAAGFRTLVQNADHQWTNMLQLLERIPKYKYSRTSDKISALLGNNDIFVYDECTKPGMLNKKSFVIEENFPMKRLGKQHDCVCPTCGKKFSYSLHLYKHLKESADLIRACHICAEIMNRDELVQHLNVYHELKPYSCKKCPAMFLNGGQYRKHLLKAHTSGSCTCGDCGCSFQSKPAFHAHQSVHTIRCCPNCDTQFRNQACYFHHVKTCCNMDPSNTQKSKITVTLQKKQNLKVKMGLRGSANKECICDYCKKKFAGKKFVAAHIQIVHMKNTHRPCIYCGKVFAAAHMTTHLKCHNQPSFECHQCGAVLKSKLGFNQHLRLHTGERPYSCQYCGEAFSASSRRSEHIRNTHKKSEIVLKHVCDQCPARFRLPNKLKQHVKTVHEQHGDEPWYECGVEEDETLPACLCHRCSEAVISAAGFKKFCQQSAQCWTEATVYLTTTPNPTDLDKTFFIFCNKGGAIFNSPDAVTALENAVTFLNGPKKKEKKKIKRQCCVCPHCSKRFSTLVNLNEHLKFMQERFCYECSVVVNKKNLAKHLLVKHNKQVVDCASCHKLFKNSTDAESHWFQNHGANTQPCNICGSGFPNERGLRAHYFLHNLFHCICGESFENSRCYNYHLTKCKPKKRSSVDLIFECDHCGVQYDKKPSLRTHIVQKHLNVLPFVCQTCGKRTSTLAHLRSHEKTHEKERKLLECYCGAKFRSKLGFKLHMRIHSGDKPYKCELCEESFLSASRRLDHVKRRHQNSTDMPHSCESCGAKFIRPWELKKHYLNVHSSIEEGTECPSGVCVTCASAALAAQEFRILVRSSEKLWLKAISNLTSLQYDDETEQARSICAFVTQNDLNVQTSKDYIGGEPKTVVNRLKRKSKTTRKPRLVRPGPTSKCPDCNKIFTSPYYLHDHFKNNGQKDACQICGTVTARGLAMWDHMIYVHNENPSMCQQCPAVFLKEGDLVNHRNEAHKPGVYTCMECGRSFPRKSTFEHHAQMHLVRTCRSCNVQFTNRSCYREHRNQCEPNAKPDSKTVPRNRRSNIRDPAVFICDYCNKKYNSRPQLKNHILWIHMDVRPYQCQWCGKRFYTPARMAEHTVVHTRARNFECDICGAKLVSKMAAVYHRRRHTGEKPYKCDDCQATFISSSRRLEHAKRKHNKGTRIPCPLCSATFVRKAELKKHIDKVHNTESKSEGTIQTHEWKVTVPPSIES
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -