Basic Information

Gene Symbol
-
Assembly
GCA_963580505.1
Location
OY757006.1:5936620-5953056[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 1.1 1e+02 4.5 3.5 1 23 219 241 219 241 0.97
2 10 0.056 5.1 8.6 1.9 1 23 248 271 248 271 0.95
3 10 0.12 11 7.5 3.7 1 23 302 325 302 325 0.97
4 10 0.0051 0.46 11.9 1.9 1 23 329 352 329 352 0.94
5 10 0.067 6.1 8.3 0.2 3 22 372 391 371 395 0.92
6 10 9.9e-06 0.0009 20.4 0.2 2 23 445 467 444 467 0.97
7 10 6.5e-06 0.00059 21.0 1.9 2 23 477 498 476 498 0.97
8 10 2.6e-05 0.0024 19.1 2.1 1 23 504 526 504 526 0.97
9 10 1.7e-05 0.0016 19.6 5.1 1 23 532 554 532 554 0.98
10 10 6e-06 0.00055 21.1 0.3 1 23 560 583 560 583 0.95

Sequence Information

Coding Sequence
ATGGATATTCAAGCTGTATGTAGAGTGTGCCTTGCTAATAGTATTAAAATGCATGAAGTAATAAGCGTACAACTACAAGAGGCTTATGAAAAACTTACTGATATCAACACCAAGATGGTGATAGAAGATAGGCCTATATCACTATGCTACATCTGCTACGCGCAGTTAAAAAGGTGCTTGCAGTTCCTGAAGGCAGCTCGGAGGTCTGAATCTATTTTGACACAGCTATACCAGGGGGCAGTTGAGctAACTTCAGCGGTAGACCATCCCCCAATCTACAGTTACTCAATCACACCTATAGAACATGTCAGCGTTTACGGACCGATCTCTGAGGGATTTGAAAGATTAGTTGAAGATTTTAAGAAAGAAATATTTGAAGTTAGCGATGAAGCTAAAATATCAGAACTCCCAGAGGTTTTAAAACCCGATCCAGACATAGATTCGAACAGTCAAGCGGACCCATCGCTACCGAGCCAGTCAAGTGACTCGGAAGATGACCTGCCTTTGACCAGCTTGAAGAGAGGCAAGGCACGGCAGAAGAGGATTTACAAGAAACGGTCCAAACTCGACGCTCGCGAAGTTTTAGTACCCAAGGAACAACAAATACAGGATGTGGTATCTCGTGCGAAGTCGCTCAACTATCTCAACTCGCCGCATCGCTGCGCTCTCTGCTACAGGGGGTTCCTAAACCACGACGCTTATAGGAACCACCAGGCTAAACATGATGAGCGTAGCGGTGCGCACGAGTGCGACGTGTGTCGGCTCCGGTATCAAAGCGCGAGGCTCCTCCGGGCGCACACGCACTCCGCACACTCGCGCCGCTACCTGTGCAACAAGTGTCCACACCTCTCGCACACTGCGCATCAAGCGTACGACCACGACCAGTGGCATAATGGACATACATACGAATGCCAACTTTGCGGACACAAATTTCTCAAGCGTACATCGTACCTCACTCACACACGCAAGGCTCACCCTTCGGATCATATCTGCAATATATGCGGCGAGCGGTTTGTGGGGAGACACGGATTGCTCATGCATAAGAGCAAAACGCACAGCAGGGCGAAAGAGGAAGAAGAAATAGAAGATACTTCCCCAAAGGAAGACCGTTTCTGTTCGTCCTGCGATATTCAGTTCGTAACTTTGAACGCTTGGAAACGACACATTATCACTTCCATCAAGCATACATTGCAAACGCAGCAAAGTGGTACATGTTTGATATGCCGCGCGTATGTACCTAATGGCGTGTCGGAACATATGCAGACCCACATGCGTCCAGTGCCCATACAGAGAGACACACAAACGCACATAAACGCGGGGCAGGCGAAAATTCAGTGTGAACagtgtCCACAATCATTCGTAAACAAGGCAAAGTTGACGGCACATGTAAGAAGAGTACATCTAGGACTGAAGTATAATAAGAATATAGTGTGCGAAGTGTGCGGGAAGAAATGCACTTCGAACGCAACACTCAAGTATCATCAAAGAACTCACACGGGCGAGAGGCCGCATCCTTGCGTTACTTGTGGGAAGCGATTCTCAGACACAAACCAACTGAGAATACATTCGCGGACGCATACCGGGGAGAAGCCTTACAGCTGCCACCACTGCAGCAAGCGGTTCGCGCAGAAACCGGCGCTTAACAGGCACTTTAGGGTACACACAGGCGCTAAGCCCTACGCCTGCGAGCTATGTTCCAAATCTTTCAGTCAGTCCAACTCTTTGAAGGTCCACGTTAGAGCGGTACATCTGAAACTACAGAGCTATCGACGAGGAAGGGCATCTACTGGGAATAACTTGCCTGGTGGACCACAGGGAGAGTTGGATAAACTTCATTAA
Protein Sequence
MDIQAVCRVCLANSIKMHEVISVQLQEAYEKLTDINTKMVIEDRPISLCYICYAQLKRCLQFLKAARRSESILTQLYQGAVELTSAVDHPPIYSYSITPIEHVSVYGPISEGFERLVEDFKKEIFEVSDEAKISELPEVLKPDPDIDSNSQADPSLPSQSSDSEDDLPLTSLKRGKARQKRIYKKRSKLDAREVLVPKEQQIQDVVSRAKSLNYLNSPHRCALCYRGFLNHDAYRNHQAKHDERSGAHECDVCRLRYQSARLLRAHTHSAHSRRYLCNKCPHLSHTAHQAYDHDQWHNGHTYECQLCGHKFLKRTSYLTHTRKAHPSDHICNICGERFVGRHGLLMHKSKTHSRAKEEEEIEDTSPKEDRFCSSCDIQFVTLNAWKRHIITSIKHTLQTQQSGTCLICRAYVPNGVSEHMQTHMRPVPIQRDTQTHINAGQAKIQCEQCPQSFVNKAKLTAHVRRVHLGLKYNKNIVCEVCGKKCTSNATLKYHQRTHTGERPHPCVTCGKRFSDTNQLRIHSRTHTGEKPYSCHHCSKRFAQKPALNRHFRVHTGAKPYACELCSKSFSQSNSLKVHVRAVHLKLQSYRRGRASTGNNLPGGPQGELDKLH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-