Basic Information

Insect: Ennomos erosarius
Gene Symbol: zfh1
Assembly: GCA_963580505.1
Location: OY757006.1:6708607-6721448[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00081 0.074 14.4 1.4 1 23 320 342 320 342 0.98

2 10 0.0072 0.66 11.4 0.4 1 23 376 398 376 398 0.98

3 10 0.00016 0.014 16.6 0.5 1 23 403 426 403 426 0.97

4 10 0.0026 0.24 12.8 0.0 3 23 434 455 433 455 0.97

5 10 0.00064 0.059 14.7 0.5 2 20 467 485 466 486 0.94

6 10 0.15 14 7.2 0.8 3 23 499 519 498 519 0.95

7 10 0.016 1.4 10.3 0.2 2 23 526 548 525 548 0.94

8 10 0.0028 0.26 12.7 1.3 2 23 559 580 559 580 0.97

9 10 3.6e-05 0.0033 18.6 1.2 1 23 586 608 586 608 0.99

10 10 6.6e-05 0.0061 17.8 1.1 1 19 614 632 614 634 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00081	0.074	14.4	1.4	1	23	320	342	320	342	0.98
2	10	0.0072	0.66	11.4	0.4	1	23	376	398	376	398	0.98
3	10	0.00016	0.014	16.6	0.5	1	23	403	426	403	426	0.97
4	10	0.0026	0.24	12.8	0.0	3	23	434	455	433	455	0.97
5	10	0.00064	0.059	14.7	0.5	2	20	467	485	466	486	0.94
6	10	0.15	14	7.2	0.8	3	23	499	519	498	519	0.95
7	10	0.016	1.4	10.3	0.2	2	23	526	548	525	548	0.94
8	10	0.0028	0.26	12.7	1.3	2	23	559	580	559	580	0.97
9	10	3.6e-05	0.0033	18.6	1.2	1	23	586	608	586	608	0.99
10	10	6.6e-05	0.0061	17.8	1.1	1	19	614	632	614	634	0.98

Sequence Information

Coding Sequence: atgGAAAATCTAATGGCTTGTCGAATTTGCTTTGCTACAAACGTGAACTTGTACGATATATGTAAATACCGCCTAAAAACCGCATATGAGAATATAACTGGACTGAGGTGGCAACAATCCACCAACAACCTACAGTATGCTTGTAGCTACTGCGCCATGATGTTGAACAAGTTCGAAATGTTCAAAGAACGGTGCCACACTTCGCAGCACATGATGGATATGCTCCTCGTGGAACATGGCCagataacAATGTATCATCTACAAAGCATTTCAAACTCATACAATTTCTATCCATACACCATGCAACTCATACAAAACGTAGATatcactattaaaataaaagaggaGATACCAGAAAGTAGCTCTGATGTTAAACTTGATGTGAATGAAGCGGGAGATATGAATGATTACGAAGAAAACTTCGAAAATGCATGTCTATCTATCAAAACAGATGACATGGGAAACAACAGCTTAGAAATACAGCTTGGCATAAACAGTGACAAACATATTGTAGGGATGGAGGGACGTCACTGCAGGCCTCACCCCCGTTTAGTGTTTGAATTAGACAGTGACGAAGAACCTTTATCGAAGAAATTTAAAAAGAGACGGAGGAAGTCCAAAAGAGATGGAAAACATGAGAATGTTCATGGAAAAACTGAGAACGATACAAATGGAAGTGAACATGTCACAAACCACAATGAACATATCACAAACCACAATGAACATACCATAAGTCCCAATGAACATGCCTCAAGTCCCAATGAACATATCACAAACCACAATGAACATTCCATAAGTCCCAATGAAAATGCCACAAATTACGAACATTTAATGGAACACACAGATAATGTTGCAGAAAACAATGAAATTGAACACAAATTAGTGTTTTTGAGTGAAGAAGAACAGTTACAGGATGTACTGAAGCGTAAAGAAACTGCGAACTATATAAATTCGGTGTACAAATGTGAACTGTGCTATAAAGGGTTCATGACGGAGGTGACTTACAGGAATCATATGGACAGACATGATCCGagCGCGGGTCCGGAATGTTGCCCAGTTTGCAAAATGCGATGGCCTGATGTTCGCTCTCTAAAAGGACATACTCTTATATCCCATGAAcgAAAATACATATGCAAAATTTGCGGTAACATATCGAAATCGAACCAAAAGGCGAAGGAACATATGCGCTGGCATGACGGCGTTAAGTTCCCTTGCCTTATATGCGGTGCCACTTTCGACCGCCGCACCAGTTTCCTCACCCATACAAGGGTGCGGCACCCGGCGTCGGTTGGGAATGCTTGCGGCATTTGCGGCGAGAAATTTGTGGGTAGAAGAGGATTGGTTTTACATATCAAGCGAGCTCATAAAAGGAAATCGGATCCGCTCGATGTAGAGCTAGAATGTGAGGACTGTCACTCACGGTTTAAGAATAAAGACGCCCTGTTAAGACATTTGGATGATGATAGTGGAGGATGTGATACCAATTTGCGtCCATGTCTCCATTGCGGTATTAGTCTTTTATCAGACGAATTATTAAAGAAACATATGAAGAATCATGTTCCTCAGAGCACAAGCACTTGTGCCGTGTGTTCGCGAACGTTCGCGAGCGCGCAAGCACTGGGCGCGCATCACGCGCGCTCGCACGGCGCTGTAACAGTTCGCCGTTCGCCCGCCGTCTGCGAACTGTGCGGAAACAAGTGTATGagCAAGGCGTCTTTGGTTCAACACTTGCGGACCCATTCCGGAGAGAAACCGTACGAATGTACCGTCTGCACCAAGCGGTTTAGTGTAAAACAACGACTACagATCCACGCACGCACTCACACCGGCGAGCGACCATTTCAATGTACTCGATGTCCAAAAGCGTTCAAACATAAAGCGGCACTAAACAGACACGACCGGGTTAgtaccaccaccatcatcatcatcatcatcatcatcttcatcatcatcaacggcctgaagaccgTTCTCTTCTGA
Protein Sequence: MENLMACRICFATNVNLYDICKYRLKTAYENITGLRWQQSTNNLQYACSYCAMMLNKFEMFKERCHTSQHMMDMLLVEHGQITMYHLQSISNSYNFYPYTMQLIQNVDITIKIKEEIPESSSDVKLDVNEAGDMNDYEENFENACLSIKTDDMGNNSLEIQLGINSDKHIVGMEGRHCRPHPRLVFELDSDEEPLSKKFKKRRRKSKRDGKHENVHGKTENDTNGSEHVTNHNEHITNHNEHTISPNEHASSPNEHITNHNEHSISPNENATNYEHLMEHTDNVAENNEIEHKLVFLSEEEQLQDVLKRKETANYINSVYKCELCYKGFMTEVTYRNHMDRHDPSAGPECCPVCKMRWPDVRSLKGHTLISHERKYICKICGNISKSNQKAKEHMRWHDGVKFPCLICGATFDRRTSFLTHTRVRHPASVGNACGICGEKFVGRRGLVLHIKRAHKRKSDPLDVELECEDCHSRFKNKDALLRHLDDDSGGCDTNLRPCLHCGISLLSDELLKKHMKNHVPQSTSTCAVCSRTFASAQALGAHHARSHGAVTVRRSPAVCELCGNKCMSKASLVQHLRTHSGEKPYECTVCTKRFSVKQRLQIHARTHTGERPFQCTRCPKAFKHKAALNRHDRVSTTTIIIIIIIIFIIINGLKTVLF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -