Basic Information

Gene Symbol
zfy1
Assembly
GCA_963580505.1
Location
OY756996.1:4931707-4943331[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.011 0.98 10.8 2.9 1 23 75 99 75 99 0.96
2 12 0.033 3 9.3 0.2 3 23 108 129 106 129 0.95
3 12 2.4e-05 0.0022 19.2 0.8 1 20 134 153 134 155 0.95
4 12 2.9e-06 0.00026 22.1 0.3 1 23 166 189 166 189 0.97
5 12 3.1 2.8e+02 3.1 5.1 1 23 195 220 195 220 0.95
6 12 0.0058 0.53 11.7 0.0 1 23 227 249 227 249 0.97
7 12 0.018 1.7 10.1 0.5 1 23 254 276 254 276 0.98
8 12 1.4e-05 0.0013 19.9 0.6 1 23 282 304 282 304 0.99
9 12 0.072 6.6 8.2 4.8 1 23 307 330 307 330 0.98
10 12 4.8 4.4e+02 2.5 0.1 10 23 350 363 337 363 0.83
11 12 0.0012 0.11 13.9 0.6 2 23 372 393 371 393 0.97
12 12 3.6 3.3e+02 2.9 0.3 3 23 401 424 400 424 0.81

Sequence Information

Coding Sequence
ATGCCACCAACACATAAAAAGGTGGGACGTCCATTAGGGTCAAAGAATAAGAAGCCATCGAAATTAGCAAGTGTGTTGAGGGAGATAAAATCCGAACCAAACTTGATCAAAAGGGAAAACGTTGctaatgataatggtgatgatagTTTTGAGAGCGATTACTCCAACCAAGATGTCTCCAACGTTTCCTTGGCTATATCAGCTGAAAAGAAAAAGgtTGTTTACAACTGTAAAAAGTGCCCCAATAAAAACTTTAAGTTTAAGAAGAATTTTCAAGAGCACCTTTTAATGGAGCACTCTACATTGCCGGGCAGCCTCGCTTGTGACCTGTGTGATGCTGTTTGCCCCAATAAATTTGCCCTAGATGCACATATTACCAAATCTCACAACAGGGAATTGTTCAGctgtaaatattgtaataaagaGTTTGTCAGGCAAGCTCATGTTCTGAGGCACATGGCTCAAAAAGGATGTGATGGCAGTGGAGTTGCATATTTTCCATGTGAAATATGCACTGCAAGGTTCACAAGAAAAGATAATCTGATAGTGCATCTCCGTCAGATGCACATAAGAAACTCATTTTACAGCTGCAAGCATGATGGTTGTGAATTCACAAGCAAGAATTTTACAAAACTGATCCGACATTGGCATTCAAAACATGCAGATATACCTGGCCAGTTTGAATGTGATTCTTGTGGCAAAGCAACAATGTCTCGTGCTGCCATGGCAAAACATCTAGAAATCCATGGAGAGAAAAAATATGCATGTGATGTGtgTGACTACAGTACACACACTATCGAGGTGATGCGTCGACACATCCTGACACACGTAGAAGACAAGCCGTACAAGTGCTCAGTGTGTGACAGCTCATACATACAGCGTGCACAGCTCGAGCGGCACTTGATGAAACACACAGGGTTTCAATGTGTTGAATGCGCAAAGGAGTTTAAATGTAAAGCCAGCTTGATCCACCACAAAAGAAGTTATCACCAGGGGCTGACTAAGCTTGACTGCCCATACTCCGATTGCAGTTACTCTCAAAACGAGTTTCCCAACGTGCAAACTTTGCTGACCCATATCAATACGCATCTAGAAGCAAGCGTCAAATCGTGGTCATGCGAGGTATGCGCTAAGCGTTTCCAATCTGAGATGAACATGCGTCGTCACCTGAGCACGCACACGCTCGACCGCCCGCGCCGCTGCATGTACTGCGTGTCGGCGCGCGCGTACGTGCGCGGCCAGCAGCTCGTGCGGCACGTGCGCAAGTTCCACGAGGACGTGTTCCGGGCGCATCTCGCGCACGTGCGCAATGTATTGGATAACAAGACGCGCGGCGAGCGTGTGTCCCGCTCGGAGCTTGAATCTGTACTGACGCTATTGGACGCGGAGGCTGAACGTATATTGGAAGGGTACGGCGGCTCTGGCGTACTGTACGGTGGAATGCAACTCGAGCAGGCACCTCAGTCCGCTAAAGAAGAGGAAAGTAATTCTCCCCTCATGTCCGAAGATGTGCTAGCTGATACTTTGAGGAGGCTTCTGGCGCATTTAATTGATGACGATACTCTGCAGTGCTTCGGTTGGCCCGATGAATCTATCGACAACatCTTGGAGAAAGTGATCGAGCAATGCGGCGCGAAGCCAGCCGACCGCGACATGTGGACCCGCGTCCAACGGCTGCGAGAGAACGCCAAACATCTGTTCCTGTACGTGGTGGACGACAAGAATGTCGCCGCGATGCTCGGCACGCATACCATCGACCAGATCATCAAGCACATCCTACTGCAAGTCGACGACGATAACACAGGTATCACCGGTGATATACACCCCGAAATAGGCGGTGACATTGAGATCGAGCTTGAAGTGAGCTAG
Protein Sequence
MPPTHKKVGRPLGSKNKKPSKLASVLREIKSEPNLIKRENVANDNGDDSFESDYSNQDVSNVSLAISAEKKKVVYNCKKCPNKNFKFKKNFQEHLLMEHSTLPGSLACDLCDAVCPNKFALDAHITKSHNRELFSCKYCNKEFVRQAHVLRHMAQKGCDGSGVAYFPCEICTARFTRKDNLIVHLRQMHIRNSFYSCKHDGCEFTSKNFTKLIRHWHSKHADIPGQFECDSCGKATMSRAAMAKHLEIHGEKKYACDVCDYSTHTIEVMRRHILTHVEDKPYKCSVCDSSYIQRAQLERHLMKHTGFQCVECAKEFKCKASLIHHKRSYHQGLTKLDCPYSDCSYSQNEFPNVQTLLTHINTHLEASVKSWSCEVCAKRFQSEMNMRRHLSTHTLDRPRRCMYCVSARAYVRGQQLVRHVRKFHEDVFRAHLAHVRNVLDNKTRGERVSRSELESVLTLLDAEAERILEGYGGSGVLYGGMQLEQAPQSAKEEESNSPLMSEDVLADTLRRLLAHLIDDDTLQCFGWPDESIDNILEKVIEQCGAKPADRDMWTRVQRLRENAKHLFLYVVDDKNVAAMLGTHTIDQIIKHILLQVDDDNTGITGDIHPEIGGDIEIELEVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00650321;
90% Identity
-
80% Identity
-