Basic Information

Insect: Ennomos erosarius
Gene Symbol: Tf2-12
Assembly: GCA_963580505.1
Location: OY757005.1:7829803-7837726[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 0.0014 0.12 13.7 0.1 1 20 111 130 111 132 0.94

2 21 0.0045 0.41 12.0 2.9 2 21 245 264 244 265 0.93

3 21 2.1 1.9e+02 3.6 0.2 3 23 271 291 270 291 0.93

4 21 3.3 3.1e+02 3.0 0.7 3 23 298 319 296 319 0.94

5 21 0.00051 0.047 15.0 0.5 2 23 325 346 324 346 0.96

6 21 0.58 53 5.4 3.0 6 21 353 368 351 369 0.93

7 21 0.0088 0.8 11.1 0.7 1 23 382 405 382 405 0.93

8 21 5.8e-05 0.0053 18.0 1.6 1 23 411 433 411 433 0.97

9 21 0.11 9.7 7.7 2.7 5 23 443 461 441 461 0.96

10 21 1.5 1.4e+02 4.1 0.5 1 23 467 490 467 490 0.86

11 21 0.019 1.7 10.1 0.1 3 20 500 517 500 519 0.94

12 21 0.00037 0.034 15.4 1.0 2 21 626 645 625 646 0.93

13 21 2.7 2.4e+02 3.3 0.0 3 23 653 674 651 674 0.90

14 21 1.9 1.7e+02 3.8 0.1 2 23 680 702 679 702 0.94

15 21 4.1e-06 0.00038 21.6 3.5 1 23 707 729 707 729 0.98

16 21 2.9 2.7e+02 3.2 3.5 2 20 733 751 733 753 0.93

17 21 3.7e-05 0.0034 18.6 0.5 1 23 779 802 779 802 0.95

18 21 0.0052 0.48 11.8 0.2 1 23 808 830 808 830 0.89

19 21 0.18 16 7.0 0.1 1 23 836 858 836 858 0.97

20 21 0.049 4.5 8.8 0.6 1 23 864 887 864 887 0.94

21 21 0.00048 0.044 15.1 0.1 2 23 894 916 893 916 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	0.0014	0.12	13.7	0.1	1	20	111	130	111	132	0.94
2	21	0.0045	0.41	12.0	2.9	2	21	245	264	244	265	0.93
3	21	2.1	1.9e+02	3.6	0.2	3	23	271	291	270	291	0.93
4	21	3.3	3.1e+02	3.0	0.7	3	23	298	319	296	319	0.94
5	21	0.00051	0.047	15.0	0.5	2	23	325	346	324	346	0.96
6	21	0.58	53	5.4	3.0	6	21	353	368	351	369	0.93
7	21	0.0088	0.8	11.1	0.7	1	23	382	405	382	405	0.93
8	21	5.8e-05	0.0053	18.0	1.6	1	23	411	433	411	433	0.97
9	21	0.11	9.7	7.7	2.7	5	23	443	461	441	461	0.96
10	21	1.5	1.4e+02	4.1	0.5	1	23	467	490	467	490	0.86
11	21	0.019	1.7	10.1	0.1	3	20	500	517	500	519	0.94
12	21	0.00037	0.034	15.4	1.0	2	21	626	645	625	646	0.93
13	21	2.7	2.4e+02	3.3	0.0	3	23	653	674	651	674	0.90
14	21	1.9	1.7e+02	3.8	0.1	2	23	680	702	679	702	0.94
15	21	4.1e-06	0.00038	21.6	3.5	1	23	707	729	707	729	0.98
16	21	2.9	2.7e+02	3.2	3.5	2	20	733	751	733	753	0.93
17	21	3.7e-05	0.0034	18.6	0.5	1	23	779	802	779	802	0.95
18	21	0.0052	0.48	11.8	0.2	1	23	808	830	808	830	0.89
19	21	0.18	16	7.0	0.1	1	23	836	858	836	858	0.97
20	21	0.049	4.5	8.8	0.6	1	23	864	887	864	887	0.94
21	21	0.00048	0.044	15.1	0.1	2	23	894	916	893	916	0.94

Sequence Information

Coding Sequence: ATGGAAATCTCACCGGACCTGCCCCAATGGCTATGCCAACCCTGCTCCTCTACTTTCACGGACTTTCTACCTTTCTGGAAGCTTTGCCGAGACTCTGTCCGTAAATGGAATCAAGTTACTAATCATTTAGAGACAATATCTGTTCATAAAAAAGCTACTACAGCTTATGTTCTTCTAACGGACAAGCCTATAACTGTAGCGGACAGAAGCAATAGAAACAAAACTCCTAAAGAAGCGCTGCGGAACATGAAACTTCGTCTCAGCTGCTTGCGCTATACAAAGGAATGCAAAAATAAGAGACTAAAGAAAATAGCCAAGGCCAAAAAGAAATTCGCATGTCCAGAATGCGGAAAAGCTTTTGAATACGTGCGCAAATTCAATAAGCATATAATCAACGTTAGAAAGCAATGCTGCAAGTATTGTCACTTAGTTGTAGAGGAGGATGCAACACTGCCCGCGTGCCTTTGTCACCGTTGCTCCGAAGCCGCTATTAGTGCAGCAGCCTTCAAGAAACTTTGCCATCAATCTGCACAGTGCTGGGATGAGGCCACCATTTTTTTAACAACCACACCCAGTCCTACAAGCTTCGTTAAGACATTTTTCATGTTTTGCAACAAAGAGGGAGGTACATTCAACAGTCCGGATGCAGTGACCACATTAGAAAATGCTGTGACGGTCCTGAATGAACcgaaaaacaagaaaaagaagaaggaaAGGAAGCGCCAATATTGTGTTTGTCAGCATTGCAGCAAGCGTTTTAGTGCTCTAGTAAATCTGAACCGGCATCTGAAATATATGCAAGAGAGATTATGTTATGAATGCAGCATCGTTGTCAACAAAAAGGATCTGGCGAAGCATTTGTTGGTCAAACATAATAAAGAGGTTATAGACTGCAGTAGCTGCCATGAGCTTTTCGAGAATTCCACGGAAGCCCAGTCGCATTGGCTTAAATACCACGGCGCGAATACTAAACCATGTAATATTTGCGGACGCGGATTTCCAAACGAACGTGGTCTTAGAGCCCATTACTGCCTGCACACCCTCCGCCACTGCTCATGTGGTAAAAGCTTTGAGAACAGTCGATGTTATAAACACCATATAACCAAATGCAAACCAGAAAAGCATAAGTCGGTTGACTCGATCTTCGAATGCGGTCATTGTGGACTACAATACGACAAAAAACCATCTTTACGTGTTCACATAGTCCAAAAACATCTGAACGTGCTTCCGTTCGTGTGCCAAACATGCGGGAAGCGAACTTCCACACTTTCTCATTTAAGGGTTCACGAGAATATTCATGAGAAAGAGCGAAAGGTGTTAAAATGTCATTGCGGGGCTAAGTTTCGCTCCAAATTGGGGTACAAGCTTCACATGAGAATCCATTCAGGGGATACACCTTACAAATGCGAATTATGCGAAGAAAGCTTCCTCTCTGCGTCTCGGAGGTTAGACCACGTGAAGAGGCGGCACCAGAGTTCCAGAGAGATGTCACACGGCTGCGAATCTTGCGGAGCAAAGTTTATAAGACCGTGGGAGCTGAAGAAACATTATCTGAACATAGAGGAAGCTACTGAATGCCCCTCGGGAGTTTGCGTGACGTGCGCAAGCGCTGCCCTCGCTGCGCAAGAGTTCCGCATATTAGTCAGGAACTCTGAGAAACTGTGGCTCAACGCTGCCACAAACTTGACAAGTTTGCAGTACGACGATGAGAAAGAGCAAGCCAGGTCGATCTGCGCGTTCGTCACAGAAAATGATCTAGACATACAGACCAGTAAGGATTACATTGGTGGTGAACCTAAAACCGTCGTCAACCGATTAAAAAGAAAAGCGAGGACCACACGGAAACCTAGACTCGTCCGACCTGGCCCGACAACCAAATGCCCAGATTgcaataaaatcttctccagTCCCTATTACCTGCACGATCATTTCAAAAATAACGGCCAGAAGGATGCTTGTCAAATTTGCGGAACTGTCACAGTCCGGGGACTTGCGATGTGGGATCACATGATATACGCACACAAAGAAAACCCGTCAATGTGTCAGCAGTGTCCTGCAGTATTCCTTAAAGAAAACGACCTGGTTAATCACCGGAACGTAGCGCACAAACCTGGGGTTTACACTTGTACAGAATGCGGCAGATCGTTCCCAAGAAAGTCAACGTTTGAGCATCACACTCAAATGCACTTGGTTAGAACGTGTCGCAGCTGCAACTTACAGTTCACAAATAGAAGCTGCTACAGAGAACATAGAACCCAATGCGAACCTAACGCAAAGCTTGACAGCAAGTCTGTACCCCGTAACCGACGGTCGAACATCCGAGACCCAGCAGTTTTTATATGCGATTACTGCAACAAAAAATATAGCTCGCGACCTCAGTTGAAGAATCATATACTGTGGATTCACATGGATGTTAGGCCTTATCAATGCCAATGGTGTGGAAAGAGGTTTTACACTCCCGCAAGGATGGCGGAGCACTCCGTAGTGCATACCCGCGCGCGAAATTTCGAATGTGACATTTGTGGCGCGAAATTAGTTTCCAAAATGGCGGCTGTTTACCATAGACGACGGCATACGGGCGAGAAACCGTACAAGTGCGACGATTGCCAGGCTACGTTTATTTCCGCATCTCGTAGGTTGGAGCACGCTAAACGGAAGCATAATAAAGGCACTAGGATTCCATGTCCTCTTTGCTCGGCCACCTTTGTTCGGAAAGCTGAACTCAAAAAGCATGTAGATAAAGCTCATAGTACAGAAGGGAGCTACACCACACCCATACTGGTGATCCCTTTACTGGTGACCCCGACGTGTCGAAACCAACGCCTGATTGACAACACTACAAGCCTTACGTCCCCTGCTTCACCTGCGCAGTCAACTGGGAACATTTCATCAGTGAAAGTCATTTCTGGAGATTCCGTATATCATAACATACTAAGTGAATACCCTGAGATTACTCGACCTTCCGGTGTCCATCGTGTTCCGAAGCATAACACCATGCATCACATACAGACTACTGCAGGGCCGCCAATAAGCAGCACACCGCGGAGACTAGCACCGGATAAGTTAAAGATAGCAAAAGACGAGTTTGCAGACATGCTGAGGAACGGAACAGCCAGACCTTCCAAATCACCTTGGTCATCACCACTTCATCTTGCGCCTAAGAAAGATAATGGGTGGCGTCCGTGCGGTGACTACAGAATGCTCAACGCTAGAACCGTACCCGACCGCTATCCCATTCGACACATTCATGACTTCGCGCATTGTCTCTCCGGCTGTCAGGTATACTCTGTCATTGATCTTGTCAAAGCTTACAACCAAATTCCAGTCTGCCCTGAGGATATTCCAAAGACCGCAATCACAACGCCGTTCGGCTTATACGAATTTCCGTTCATGACGTTCGGACTACGTAACGCCGGACAAACGTTTCAACGATTTGTGGACGAGATGCTCAGGGGCCTTGAGGAGTTCTGTTTTCCATTTCTTGACGATTTCCTGATTTTTTCACCTGATGAGGAGTCACACAAGAAGCATCTTCATCTGCTCTTCAACAGACTCAAGGAATACGGCATGGTAATCAACACTAACAAGTGCATATTCGGTGTATCGGAGATAACGTTTTTAGGACACAGCATCTCAGCAGCTGGCACTAAACCATTATCATCAAAGGTAGAAGCAGTTGCGAACTTTCCACCACCGAAAACTGTGAGAGAATTGCGAAGATTTCTTGGAATGGTGAACTTTTACAGAAGGTTCATTCCTGACGCAGCGCGGTACCAAGCTCCTCTGAATGCACTGCTCACGGGATCAGTTAAAGGTTCACACCCCGTGCATTTATCTGAAGAAGCTACGAAAGCATTCACCGACTGCAAAGAAAGTCTCTGCCAAGCAGCACTACTCGCTCATCCAGACTGTCAAGCGAAGCTCGCCATAGTCACCGACGCTTCAGACACGGCAATGGGCGCAGCTTTACAACAGCATAGAGACGGTCAGTGGGAACCTTTGGCATTTTTCTCTCGGAAGCTTTCGCCATGCCAGCAGAAATACTCGCCATATGACAGAGAACTTCTCGCTATCTACGAAGCTATAAAATACTTTCGTCACATGGTAGAAGCGAGAGATTTCATCATATACACGGATCACAAGCCCATTACTTTCGCATttcattcacgaaaagaaaattgCTCACCAAGACAGTTTAGACATCTGGATTTCATTTCACAATTTTCGACAGACATCAGGCATATATCAGGAAAGGACAACGTTGTGGCTGATAGTTTATCACGCATCGAAGAGATTACTCAGCCCATCGATTTATCCAACCTTGCTCAAGCACAAAGCACAGATCCTGAGTTACAACAACTTTTGGAGAGCAATACTTCACTGCGCTTGACTAAAATCAAACTGCCTGGATCTCACACTGAAATTTACTGTGACAAAAGCAGCAATGTGGCCAGACCATACGTGACCAAAGACATGCGACGGCAAGTGTTCGAAAACTTGCATTCTTTCAGCCATCCTGGCACAAATGCGACGACGAAGTTAATATCGGAACGCTACGTATGGCCTAGTATGCGCAAAGACTGCAGAGAGTGGACTCGTTCCTGCCTAGCATGCCAACGATCGAAAATTATACGTCATGTCTCATCTCCATTAGCTTCATTCAACTTACCTCGAGCCAGATTCATGAAAATCCACATAGATTTGATCGGACCTTTGCCAATCTCGCAAGGGTACCGCTACTGTCTCACATGTGTTGATCGCTTTACACGATGGCCCGAGGCTATACCATTACAGGAGATAACAGCTGAAACAGTGGCAAAAGCTTTAGTACACGGATGGATATCCAGATTCGGCTGCCCTGAAGACATTGTCACTGATCGTGGTCGACAGTTTGAATCAGAACTTTTCAAGCATCTGTCCCACATTATCGGATTTCAACGCAGACGAACTACAGCCTATCATCCGGCGTGCAATGGTCTCGTAGAAAGATTCCACAGACAGCTCAAAGCCGCCATTACATGCCATGCGACCAGCAGCTGGCTAGAAACACTTCCACTCGTACTACTGGGTATCCGGGCGGCGTTTAAGGAAGACCTACAAGCCACTCCAGCTGAGCTCGTATACGGAGAAACGCTACGACTCCCAGGTGACATTTTTTGTCAACAGGCTGATGGCACAGAGGACTTGACAGTATACACTGACAGACTGCGCACATTCGCCAAGAATTTGTTGCCATCACCAACATCACGCCATGGGAATAATCGTTCCATCTTCATCTTCAAAGATTTGGCAACAGCATCCCACGTTTTTCTACGAGATGACACTTCTCACCCATCATTTCAAGCAGCTTACACAGGCCCGCATGAGGTGGTAAAACGGGGGGATAAAGTTTTCAAGCTCCGCATAAAAGGCAAGGAAGTCACGGTATCAGTGGACCGCATCAAACCTGCCTACATACTTCGTGAGTCGGACCATTCGCCAGCAGCGGCAGCAGCAGAACCTGAGACTCGAGACGCTCCAGTGACCACCACTCGATCAGGACGAATAGTCCGCTTTCCTGAGAGGTATTAA
Protein Sequence: MEISPDLPQWLCQPCSSTFTDFLPFWKLCRDSVRKWNQVTNHLETISVHKKATTAYVLLTDKPITVADRSNRNKTPKEALRNMKLRLSCLRYTKECKNKRLKKIAKAKKKFACPECGKAFEYVRKFNKHIINVRKQCCKYCHLVVEEDATLPACLCHRCSEAAISAAAFKKLCHQSAQCWDEATIFLTTTPSPTSFVKTFFMFCNKEGGTFNSPDAVTTLENAVTVLNEPKNKKKKKERKRQYCVCQHCSKRFSALVNLNRHLKYMQERLCYECSIVVNKKDLAKHLLVKHNKEVIDCSSCHELFENSTEAQSHWLKYHGANTKPCNICGRGFPNERGLRAHYCLHTLRHCSCGKSFENSRCYKHHITKCKPEKHKSVDSIFECGHCGLQYDKKPSLRVHIVQKHLNVLPFVCQTCGKRTSTLSHLRVHENIHEKERKVLKCHCGAKFRSKLGYKLHMRIHSGDTPYKCELCEESFLSASRRLDHVKRRHQSSREMSHGCESCGAKFIRPWELKKHYLNIEEATECPSGVCVTCASAALAAQEFRILVRNSEKLWLNAATNLTSLQYDDEKEQARSICAFVTENDLDIQTSKDYIGGEPKTVVNRLKRKARTTRKPRLVRPGPTTKCPDCNKIFSSPYYLHDHFKNNGQKDACQICGTVTVRGLAMWDHMIYAHKENPSMCQQCPAVFLKENDLVNHRNVAHKPGVYTCTECGRSFPRKSTFEHHTQMHLVRTCRSCNLQFTNRSCYREHRTQCEPNAKLDSKSVPRNRRSNIRDPAVFICDYCNKKYSSRPQLKNHILWIHMDVRPYQCQWCGKRFYTPARMAEHSVVHTRARNFECDICGAKLVSKMAAVYHRRRHTGEKPYKCDDCQATFISASRRLEHAKRKHNKGTRIPCPLCSATFVRKAELKKHVDKAHSTEGSYTTPILVIPLLVTPTCRNQRLIDNTTSLTSPASPAQSTGNISSVKVISGDSVYHNILSEYPEITRPSGVHRVPKHNTMHHIQTTAGPPISSTPRRLAPDKLKIAKDEFADMLRNGTARPSKSPWSSPLHLAPKKDNGWRPCGDYRMLNARTVPDRYPIRHIHDFAHCLSGCQVYSVIDLVKAYNQIPVCPEDIPKTAITTPFGLYEFPFMTFGLRNAGQTFQRFVDEMLRGLEEFCFPFLDDFLIFSPDEESHKKHLHLLFNRLKEYGMVINTNKCIFGVSEITFLGHSISAAGTKPLSSKVEAVANFPPPKTVRELRRFLGMVNFYRRFIPDAARYQAPLNALLTGSVKGSHPVHLSEEATKAFTDCKESLCQAALLAHPDCQAKLAIVTDASDTAMGAALQQHRDGQWEPLAFFSRKLSPCQQKYSPYDRELLAIYEAIKYFRHMVEARDFIIYTDHKPITFAFHSRKENCSPRQFRHLDFISQFSTDIRHISGKDNVVADSLSRIEEITQPIDLSNLAQAQSTDPELQQLLESNTSLRLTKIKLPGSHTEIYCDKSSNVARPYVTKDMRRQVFENLHSFSHPGTNATTKLISERYVWPSMRKDCREWTRSCLACQRSKIIRHVSSPLASFNLPRARFMKIHIDLIGPLPISQGYRYCLTCVDRFTRWPEAIPLQEITAETVAKALVHGWISRFGCPEDIVTDRGRQFESELFKHLSHIIGFQRRRTTAYHPACNGLVERFHRQLKAAITCHATSSWLETLPLVLLGIRAAFKEDLQATPAELVYGETLRLPGDIFCQQADGTEDLTVYTDRLRTFAKNLLPSPTSRHGNNRSIFIFKDLATASHVFLRDDTSHPSFQAAYTGPHEVVKRGDKVFKLRIKGKEVTVSVDRIKPAYILRESDHSPAAAAAEPETRDAPVTTTRSGRIVRFPERY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -