Efla007173.1
Basic Information
- Insect
- Endotricha flammealis
- Gene Symbol
- ZFX
- Assembly
- GCA_905163395.1
- Location
- LR990881.1:8687521-8691048[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 6.4e-06 0.00054 21.1 0.3 1 22 106 127 106 127 0.95 2 17 0.047 4 9.0 0.6 3 23 133 153 132 153 0.96 3 17 0.035 3 9.4 2.4 1 23 158 181 158 182 0.96 4 17 0.011 0.92 11.0 1.7 1 23 186 208 186 208 0.96 5 17 0.00095 0.081 14.3 0.8 1 23 243 266 243 266 0.95 6 17 0.00012 0.011 17.1 0.5 1 23 272 294 272 294 0.96 7 17 0.16 13 7.3 0.5 1 23 328 351 328 351 0.86 8 17 1.4e-05 0.0012 20.1 0.5 2 22 473 493 472 496 0.89 9 17 0.0065 0.55 11.7 1.0 2 23 499 521 499 521 0.96 10 17 0.14 12 7.5 1.0 3 23 528 549 527 549 0.97 11 17 2.5e-05 0.0021 19.3 1.0 2 23 555 576 554 576 0.96 12 17 0.66 56 5.4 2.2 2 21 580 599 580 600 0.92 13 17 6.3e-06 0.00053 21.2 0.2 1 23 626 649 626 649 0.94 14 17 0.0053 0.45 12.0 0.8 1 23 655 677 655 677 0.95 15 17 0.043 3.6 9.1 0.1 1 23 683 705 683 705 0.98 16 17 0.008 0.68 11.4 0.3 1 23 711 734 711 734 0.95 17 17 0.085 7.2 8.2 2.9 3 23 742 763 740 763 0.91
Sequence Information
- Coding Sequence
- ATGGAGTCGCTGCCTGGACTGCCAAACGGGATCTGCAGAGAATGTTCAGAGGGTACCATGTCAGCTATAAAATTTAGACAGCTCTGCAAAGTGTCCATAGAGCATTGGGAATGCGCTACGAACTTCTTGACAGAAATCAACGAACCGAGTACAGAAGATAAGGCTTATTATGTATTTTATACGGAAGAAGCCCAAACAGTCTTAAGAGACCAAATTGGTAGAGTGGATAACGTAACAGAGGCTGTAGAAAGACTTAAGGGTTATTTAGAAAACATAAGGAAGCCAAAAAAGAAGAAATCTAACAGTTTACTATCATTTTTTTGTCCAGATTGCGGAAAGAACTTTTCATTGCCCAGTTATTTGAATTCGCATTTGAAAACTACAATGAAAAGAGCTTGTACTGTCTGTGGATGTGTTTTACCTAAATCACAACTAGCAAAACATATGATAAAGACACACAACTCAGTAATATATAGCTGTAAAGTATGCTACGAGCTATTCCCTGATCAGAAATCAGTTTTAAGACATAAAAAGAAAGTGCATCACCCGAATAGACATAACTGTACAACTTGTTGGAACTCTTTTGTGAATATCAGAGCGTTAAATACTCACATGTATTCACATACGTTATTCCATTGTAGATGTAGACAAAGTTTCGATAATATGAAATGTTTTAAATATCATCAAAGTAGATGTAGTAACAAGGAAATGAGCATTCATAATCGTTATGTATGCGATCACTGCGGTTCTACATATGATAAGAAACCTTCGTTAAGGATTCATATAATACAGAAGCACTTGAATGTATTGCCGTACGTCTGTGGGACATGTGGGAAGAGGACGTCGACATTAGGTCACTTGCGGTCTCATGAAGCAGTTCATACAACAATTCGGAAGATTTTCGAGTGCTTCTGCGGTGCAAAAATGCGTACGGAGTTAGGTTATAATCTACATCAGAGGATTCACACTGGGGAGAAGCCTTATGAATGCGATGAGTGTGGGGAGAAGTTTCTATCTGCTTCTAGAAGGTCGGATCATGTTAAAAGAAGGCACAGAAGCACTAGAGACATGGCACATGGCTGTGATATATGCTCGGCTAGGTTTATATGTGAAGACCATCTCTGCCCTCTCGGTGTTTGCGTCAAATGCGTATCTAACGCATTGGCAGCACAGGAATTCAGATACCTTGTGAGAAACTCGCAAAAAACATGGCTGAAAGCTTTGAAATCACTAGAAGACCTCCCGAACGCGGCATCACCGCCTGTCAAGACACTATGTGCCTTCATAAAACCAGAAACATTGACATTACAGACATTTAAAAATTATACCGGAGCAGATACAAAAACGGTTTTGAATAAATTAAAAAGTAGATTAACTAAAAAGAAACCAAGGATAGTTAGAAGCGGTCCACCTTGCGACTGTCCTGACTGCGGCAAGGAATTCGTCAGTCCTTATTATCTTAGTCAACATTTGAGGAATAGTGGACACAAAGAAGTCTGTTCTCATTGTGGTGTTGTATTCTTTCGTGGGAAACAAATGAAGGAGCATCTAATGAAAGCACACGGCAAAGACTTAATACTCTGTGGTCTATGTCCGTTATTATTTAAAAACGATACACAGGTAAAAAAACATAGAAGAAAGTACCATAAACCGGGTGCATTGACCTGTTCTGATTGTGGTAGATCGTTCCCGAGAAAGAATTCCTTTGAAACTCACTCACAAATGCATGCGGTAAGGACATGTAGGAGTTGTGGTGTACAGTTTTCGAATCGTGGTTGTTATAGAGAGCATAGGTCGAAATGTGAGCCTGATGCGAAACCTAATACTCAAACTATACCAAAAAGCAAGCGATCTAATGTTCGAGACCCTGCGTATTTTATTTGTGATTATTGTGACAAGACTTATACTTCAAGACCACAGTTACAGAACCATATAATATGGATACATATGGACGTAAGACCTCATCAGTGTCAGTGGTGTTCAAAAAGGTTTTACACGGCAGCCAGACTGGCTGAACACACAGTGGTTCACACTAGAGTTCGAAATTTCGAATGTGACATTTGCGGTATCAAATTAGTTTCAAAGATGGCCGCCGTATACCATAGACGAAGGCATACGGGAGAGAAGCCATATGCGTGTGAAGATTGTGACGAGAAATTCATATCGGCGTCGCGTAGAACGGAACATGCTAAACGTAGACACGGGAAAGGTCCCAGACACCTCTGTATACATTGTCCGTCGAGTTATGTCACTGCTTTTGAACTCAGGAGGCATATAAAGAAGTTTCATCAGACGCCATGTGCAACAGAGTTGCCGCCAACTACAGTTGTCAATGAGAATTATTTGAAAATTTAG
- Protein Sequence
- MESLPGLPNGICRECSEGTMSAIKFRQLCKVSIEHWECATNFLTEINEPSTEDKAYYVFYTEEAQTVLRDQIGRVDNVTEAVERLKGYLENIRKPKKKKSNSLLSFFCPDCGKNFSLPSYLNSHLKTTMKRACTVCGCVLPKSQLAKHMIKTHNSVIYSCKVCYELFPDQKSVLRHKKKVHHPNRHNCTTCWNSFVNIRALNTHMYSHTLFHCRCRQSFDNMKCFKYHQSRCSNKEMSIHNRYVCDHCGSTYDKKPSLRIHIIQKHLNVLPYVCGTCGKRTSTLGHLRSHEAVHTTIRKIFECFCGAKMRTELGYNLHQRIHTGEKPYECDECGEKFLSASRRSDHVKRRHRSTRDMAHGCDICSARFICEDHLCPLGVCVKCVSNALAAQEFRYLVRNSQKTWLKALKSLEDLPNAASPPVKTLCAFIKPETLTLQTFKNYTGADTKTVLNKLKSRLTKKKPRIVRSGPPCDCPDCGKEFVSPYYLSQHLRNSGHKEVCSHCGVVFFRGKQMKEHLMKAHGKDLILCGLCPLLFKNDTQVKKHRRKYHKPGALTCSDCGRSFPRKNSFETHSQMHAVRTCRSCGVQFSNRGCYREHRSKCEPDAKPNTQTIPKSKRSNVRDPAYFICDYCDKTYTSRPQLQNHIIWIHMDVRPHQCQWCSKRFYTAARLAEHTVVHTRVRNFECDICGIKLVSKMAAVYHRRRHTGEKPYACEDCDEKFISASRRTEHAKRRHGKGPRHLCIHCPSSYVTAFELRRHIKKFHQTPCATELPPTTVVNENYLKI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -