Efla007079.1
Basic Information
- Insect
- Endotricha flammealis
- Gene Symbol
- Bcl11a
- Assembly
- GCA_905163395.1
- Location
- LR990881.1:7764068-7781364[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.38 32 6.1 0.0 3 23 51 71 49 71 0.95 2 15 0.0019 0.16 13.4 2.8 1 23 174 196 174 196 0.99 3 15 1.6e-05 0.0014 19.9 0.4 1 23 202 225 202 225 0.97 4 15 0.17 14 7.2 6.9 1 23 230 253 230 253 0.94 5 15 0.00024 0.02 16.2 1.0 2 23 400 421 399 421 0.97 6 15 0.00037 0.031 15.6 2.2 1 23 427 449 427 449 0.98 7 15 1.4 1.2e+02 4.3 8.3 1 23 513 535 513 535 0.97 8 15 0.0033 0.28 12.6 1.4 1 23 542 564 542 564 0.97 9 15 0.0052 0.44 12.0 1.3 1 23 570 592 570 592 0.95 10 15 1.9e-05 0.0016 19.6 1.1 1 23 598 620 598 620 0.98 11 15 0.0012 0.1 14.0 1.9 1 23 629 651 629 651 0.98 12 15 0.00053 0.045 15.1 0.6 3 23 699 719 698 719 0.97 13 15 0.06 5 8.6 5.8 1 23 736 758 736 758 0.95 14 15 3.5e-07 3e-05 25.1 0.9 1 23 764 786 764 786 0.99 15 15 0.00063 0.054 14.9 6.5 1 23 792 815 792 815 0.98
Sequence Information
- Coding Sequence
- ATGGATATAAACATGTGGATAGGCCCTTCCATACAAAGAGTACATCCTATCATGTTATTACTCAAAGAGGAGAGGAAATACGTGAGACGTGGCAAACAGAGCAGTTATTGGTCTAAGAAGATACTAGACGAAAATTTCAAGTTTTACGGATGCGCCGTTTGCAACGTAGACTTTGCCACGTTAAACGAGTTAGACCAACATGTAACTATACATAAGGATAGAATAACGAGCTATGACTTGAAATTGCAAAACCAGAAGAAAAGAAAATTAAAGAAGAAGGAGTTGAAGCGAATGAAGAACAAAAAAGAAGAATTGGAAATCAAACCGGAGGACGGTTATATTGGTAACGAGAAAGCAACGGAGTATAACGGGAGCGCAACGGATATTAGCAACGGTAATCAGGATTCAAACATAGAAAATGATTCGAAAGTAAACGTTATGATTGAGGTCAACAAACAAAATGGTGAAACGGAGAATATTGAGAAGAACAATAAGGATAAACTCAATTTGGAGAAGATATACAAATGTTTCGCTTGTCAGAAACAATTTACTCTAAGTTATTATTTGAAATTACATGTGAGGTCTCATACAGATGAAAAGCCATATACTTGTAGTATATGCGGACAGTCATTTATAACAGCGAGCAAACTCGGGAGGCACAATAAGCGTATACATCTATCTATCAGATATCAGTGTCGGATATGTTTTAGGTTTTTTACGAAATTCGAATGCTTGACCCGACACTTTGACAAGCAGCATCCTGATGACAAATTGGAAGGAGAACCATATGATTACAACGCAATATTGCCATATCTGAAAGAGCTAGAAGAACAATTGATTCACAAGAAAGAGGATCCCAAACCGAAACCCGAGGATCCTTGGGACCGGTGGCTTCCACCTGTGCAGGAGACGACGGAGACTGAACTCAAGGTTGAACTAGAACCAGAGAAACCCCTAGAAGTATTAGTAGAAGATGTGAAAGTCAATAATCACCTAGAAATTGAAGTGAAATGCGAGGAAGATATTAAAGACGAATATGAGGACGAACACTTCGACGATGGCGGCGGTGGTGACGAGAAAGATGGCAGCGGCTCTGACGACAACTACTTCCCGTCAAACACATGGGTGCCGACACCAAAAGCAGAAGTGGACACGAAGGAAGCGAAAAAGAGTAAAAAGAAGACAGATCCCCCGTTGCAATGCGAGATATGCCAGAAGAAGATCAACTCGATGTCGTACTACAGAGTGCATATGCGCACTCACACGGGGGAGAGACCCTTCAAGTGCTACTTGTGCGATCGAGGGTTCATCACCGCGAGCAAGATGCACAGGCACGTGCTGACACACAAGGAGAGTTGGCAAGACGAAGAAATGGCTTTGAAACAGGAGAATGTGAAGTTAGAAGACGATGAGGACGGCGACGGAAGTGATGATGAGAAGAAACCGGACATCAAAAAAAAAAGAAAACCAAAGACAACAACAGCAAAGAAGGCTAGAATTAAAAAGGATCCCAATGACAGGCATTTGAGATGGCAACACACGTGCGAGTTCTGTCACAGGAAGTTTTTGCATCTGGAAACACTGCAGGTTCACAAAAAGAGTCACGCCGGCGAGGAGTTAGTACACAAATGTCACTACTGTTTAACGGAATTCCCGCAAGAGGGCGCGCTTAAAGAACACGAAGCGACACACACTGGTCCCAAACCATATTTATGTACCATATGCGGCAGGTATTACAAACGGCGGGAGGCTATGATTTACCACAAAAAACAACATCAACCAGAGAAGGAATACGTATGCGATATTTGCTCAAAGTCATTCACGGCGCCATGCAAACTGCAGAGGCATATAGCTAGGCATAGCGAGAACAAATTTGTATTACGATATGAGTGTCCGGTTTGTGCACACATGTTTAATACCAAGTACCATGTGCAAATGCATTTAGCGTCACATCAAAAGGAAGGACTCATCCAAGAAGAAAATCGTAACGAAATCCTAGCAATGGTATTACAGAACGCAAGGAAATTCCCGAAACAAGGCGATACGCCTTCAAACTTAACAGATGTGATACCGTCGGACGAAAGGTCGAGGATTTGCAACATATGCGGGGAGATATTCCAACATTTCTACTATTTGGAGGAGCATCTGAAGAGCCACGGGTCCAGAATCGCAATAGACGACATAACGAGGGAGGAAGAGAAGAAACATATATGCAAAGTATGCAACAAGGGTTTTAAACTACATTATTATCTTAAGTTACATAGTTTTACGCATACAAAAGAAAAACCATATACATGTCAACAGTGTGGGAAAGGTTTCATAACAAAGGGCAAACTCAAAAGACATATAGAGACCCATACTGGCTTAAAAAAGTACCAATGTCATATATGTTGTAAATTCTTCACGAGAACCAGTTATTTAAGAATCCATGTCAGGACGATACATGGCACGCAAGATTATAACTTCAGACTGGACAAAGACTATATGGGAGGGCTGGGTATGAACTTAAATATGGGACATCATAGTGTTTAG
- Protein Sequence
- MDINMWIGPSIQRVHPIMLLLKEERKYVRRGKQSSYWSKKILDENFKFYGCAVCNVDFATLNELDQHVTIHKDRITSYDLKLQNQKKRKLKKKELKRMKNKKEELEIKPEDGYIGNEKATEYNGSATDISNGNQDSNIENDSKVNVMIEVNKQNGETENIEKNNKDKLNLEKIYKCFACQKQFTLSYYLKLHVRSHTDEKPYTCSICGQSFITASKLGRHNKRIHLSIRYQCRICFRFFTKFECLTRHFDKQHPDDKLEGEPYDYNAILPYLKELEEQLIHKKEDPKPKPEDPWDRWLPPVQETTETELKVELEPEKPLEVLVEDVKVNNHLEIEVKCEEDIKDEYEDEHFDDGGGGDEKDGSGSDDNYFPSNTWVPTPKAEVDTKEAKKSKKKTDPPLQCEICQKKINSMSYYRVHMRTHTGERPFKCYLCDRGFITASKMHRHVLTHKESWQDEEMALKQENVKLEDDEDGDGSDDEKKPDIKKKRKPKTTTAKKARIKKDPNDRHLRWQHTCEFCHRKFLHLETLQVHKKSHAGEELVHKCHYCLTEFPQEGALKEHEATHTGPKPYLCTICGRYYKRREAMIYHKKQHQPEKEYVCDICSKSFTAPCKLQRHIARHSENKFVLRYECPVCAHMFNTKYHVQMHLASHQKEGLIQEENRNEILAMVLQNARKFPKQGDTPSNLTDVIPSDERSRICNICGEIFQHFYYLEEHLKSHGSRIAIDDITREEEKKHICKVCNKGFKLHYYLKLHSFTHTKEKPYTCQQCGKGFITKGKLKRHIETHTGLKKYQCHICCKFFTRTSYLRIHVRTIHGTQDYNFRLDKDYMGGLGMNLNMGHHSV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -