Ecoc022073.1
Basic Information
- Insect
- Endomychus coccineus
- Gene Symbol
- topi
- Assembly
- GCA_958510875.1
- Location
- OY294068.1:31503629-31521390[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0022 0.52 12.6 2.1 2 21 112 131 111 132 0.94 2 12 3.7e-05 0.0088 18.1 2.3 1 20 157 176 157 179 0.95 3 12 0.0091 2.2 10.6 2.0 3 23 187 207 186 207 0.95 4 12 0.11 26 7.2 0.5 2 14 226 238 225 243 0.87 5 12 7.1e-05 0.017 17.3 1.0 2 23 306 327 305 327 0.97 6 12 0.077 18 7.7 2.7 2 21 370 389 369 393 0.83 7 12 0.023 5.4 9.4 0.1 1 23 541 563 541 563 0.96 8 12 7.3e-07 0.00017 23.5 2.4 1 23 569 591 569 591 0.98 9 12 0.02 4.8 9.5 0.2 1 23 597 622 597 622 0.96 10 12 0.34 81 5.7 2.5 1 23 628 650 628 650 0.85 11 12 4.8e-05 0.011 17.8 1.6 3 23 658 678 656 678 0.97 12 12 1.8e-06 0.00043 22.3 0.8 1 23 684 707 684 707 0.98
Sequence Information
- Coding Sequence
- atgaataattatgataatataatttttaaagtGTATAGAGTTAATAGGTCAGGGATCATTACCTCATCATTTCAATATGAACAAGAATTTTATAGTcatgaaataatatcaaaaattccaATATCCTGTGAAGATGTAAGTTTTAATCTAAATACAAATCTCAATAGAATAAATTTAagtaacaaaaattttcaatgtgAAGATGAAAATCGTCCTAATGTTACCATTATTAAAATCAAGAAATGCCTGAATTTGTCACAAAATTCACATTCAAATTACTTACAAAATGGCATGAAGTACACAAATGGTCTATTGAATTTGCCTACAATGATCAGATGTCAAAACTGCGAAACTAATTTTCCAACTAAGTACCAATATCAACGGCATCAATGTGAATTTAATGCAGAAAAGGTGGTTTTGAAGCCAAATGCTGATCTGAAAGACATCAATAAAGGAATGAGAATCAAATATGATTGCAACACTTGTGGCAAACAATTCGTTAGCAGAAACAACTTGGAGCGACATCAGGCTTGTCATGAAAATTCTAAAGACAACATATGTGAACACTGCAATAAGCAATTTGTTAGTGAAAATCGATTGAGAATCCATAAAGAAAATCATTGTAAGAAAGCTGGAGATATATCCAAGTTTTATCGCAGTGATGTAGCTGTTTGGAAATGCAAGAAGTGTCATGAAGTTTTTTCATCCATAAGTAGTGCAAATTTTCATGTAGAATGTTGCAAAGAGTACGTATTTTTATATGATACGAAAATTGATTCTGGTCAGAATAACAGTATTGACTTATTGAAGCAGGAAATAAGTAATCTCGTATCTTTAGTAAACGAAGAAAATATGAACCAGAAGAATATAATTGACAATCATAACATCGAAAAAATTTTAACAGAAATTCTGTTACAATGTGAATTTTGTAATCGTACCTATGCAGATAAAAATTTGCTATTATTGCATCAAAGAAAACATACAACTGAAAAGAATTACGAATGTGTAAATTGTGAAAGTACATTTGACTCCTATGCAGTAGCTGCACAACACTGGTTGAAGATATGTTCTGAAAATGCAAATTTATTCTACTTACCAAAGTTAACTTATTGTGAGTATTGTGATAGAACTTTCAAATCCCATGAAATTTTATACACTCACAAGATTAAAAAGAAGCATTATACaataaaattacataaaaaGAATGATTCAATTGCCAATGATAGCAgtacaataaaagaaaaatctattgaaaacaaTGATGCCATCAATAAATTGATTGAAGATGTTTTAATCACACTTGACAGACCTGTTAACAAAACTAATCACAAAAGCTTACATTCCAAAGACgatgaaaataaagaaaataacaaCCAAGAAGATTGTTCCGCAAATGATGTTTCGAGTCAACAAAGTGATAGTGGCATGCAAGAAAACGCGGATGAAcctgagaaaaaaaaacgaggCCGAAAACGTAAATGGCCTAAGCAAATCATTAAAAGTAAACGGTTGAATAGTTTAACCGATGATGGATTTAAATATCAATGTGAAAGGTGTATACTTGTGTGGGACAACATAaatgaacttgaagatcatAGAGAGAAAGAACATGCGGCCAGTTATAACTGTGAAGAATGTGGACAGATTCTGCACAGTGCTAAAGCATTACTGATCCACAGTCGAGCTCATAAAAGTCTGAAACCATATGTGTGTGATACATGTGGAAGAAGTTATTCGCAAACTTCACATCTCTGGCAGCATATGAGATTCCATCAAGGAATAAAGCCATTTGCTTGCCCACATGAAGGTTGTGAAGCGAGATATACAATAAGACCCGACTTGAAAGATCATATTAGAAAAGTGCACACCCGAGAGAGGCCATTCAAGTGTGCCGTTTGCAATAAATGCTTCTTAACTGGATCTGTATATTATCAGCATCGATTGATACATACAAATGATAGAAGATATGGCTGTGATGTGTGCCATAAGCGATTTTTCAGAGCAGATGCTCTTAATAACCACAAAAGGATCCATACTGATGAACGTCCGTATCCTTGTAATGTTTGTGGACGAGAATTCAGACAGAAAGGTGATCGTAATAAACATCTAAGAACTCAACATCCCGATGCaataatgaattga
- Protein Sequence
- MNNYDNIIFKVYRVNRSGIITSSFQYEQEFYSHEIISKIPISCEDVSFNLNTNLNRINLSNKNFQCEDENRPNVTIIKIKKCLNLSQNSHSNYLQNGMKYTNGLLNLPTMIRCQNCETNFPTKYQYQRHQCEFNAEKVVLKPNADLKDINKGMRIKYDCNTCGKQFVSRNNLERHQACHENSKDNICEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVAVWKCKKCHEVFSSISSANFHVECCKEYVFLYDTKIDSGQNNSIDLLKQEISNLVSLVNEENMNQKNIIDNHNIEKILTEILLQCEFCNRTYADKNLLLLHQRKHTTEKNYECVNCESTFDSYAVAAQHWLKICSENANLFYLPKLTYCEYCDRTFKSHEILYTHKIKKKHYTIKLHKKNDSIANDSSTIKEKSIENNDAINKLIEDVLITLDRPVNKTNHKSLHSKDDENKENNNQEDCSANDVSSQQSDSGMQENADEPEKKKRGRKRKWPKQIIKSKRLNSLTDDGFKYQCERCILVWDNINELEDHREKEHAASYNCEECGQILHSAKALLIHSRAHKSLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCAVCNKCFLTGSVYYQHRLIHTNDRRYGCDVCHKRFFRADALNNHKRIHTDERPYPCNVCGREFRQKGDRNKHLRTQHPDAIMN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -