Basic Information

Insect: Empis stercorea
Gene Symbol: zfh1
Assembly: GCA_949752835.1
Location: OX457086.1:62269344-62312673[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.076 7.7 8.0 0.3 2 23 66 88 65 88 0.96

2 9 0.00046 0.047 15.0 2.5 1 23 281 303 281 303 0.96

3 9 0.00024 0.025 15.8 3.6 2 23 310 331 309 331 0.97

4 9 7.3e-06 0.00073 20.6 5.9 1 23 340 362 340 362 0.99

5 9 0.00056 0.056 14.7 1.0 3 21 370 388 368 389 0.94

6 9 0.022 2.3 9.7 0.5 2 21 724 743 723 744 0.92

7 9 8.7e-06 0.00087 20.4 0.9 1 23 1112 1134 1112 1134 0.94

8 9 7.9e-05 0.0079 17.4 7.2 1 23 1140 1162 1140 1162 0.98

9 9 0.0036 0.36 12.2 4.3 1 21 1168 1188 1168 1189 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.076	7.7	8.0	0.3	2	23	66	88	65	88	0.96
2	9	0.00046	0.047	15.0	2.5	1	23	281	303	281	303	0.96
3	9	0.00024	0.025	15.8	3.6	2	23	310	331	309	331	0.97
4	9	7.3e-06	0.00073	20.6	5.9	1	23	340	362	340	362	0.99
5	9	0.00056	0.056	14.7	1.0	3	21	370	388	368	389	0.94
6	9	0.022	2.3	9.7	0.5	2	21	724	743	723	744	0.92
7	9	8.7e-06	0.00087	20.4	0.9	1	23	1112	1134	1112	1134	0.94
8	9	7.9e-05	0.0079	17.4	7.2	1	23	1140	1162	1140	1162	0.98
9	9	0.0036	0.36	12.2	4.3	1	21	1168	1188	1168	1189	0.96

Sequence Information

Coding Sequence: aTGTTGTCTTGTTTGGTACCACGTTTTGGACAAGAGGACAAAATTAATATGCCATCTTCAACAGCATTTTCATTACaatTTCCATCGTTGGCATCAAGTCTAcatcatcataataatattaataaaaatgatgatagTTCATCAATAGCAGCAGCACATGCAGCTAGTACAATTGGAGGTGGtgattttattgttaaatgtccACAATGTCATCAACGTTTGTCTGGATTTCcggcACTTCGTGAACATTTAGAAACCGAACATCCacatgaaaaacaaaattatgaaagttcaccaaattatttattaccatttggtaattttaataataataatttaaatggaaTTGATCATCAccatcagcaacaacaacaacaccatcaTCACCACAATAATCATCGTAATAGTcgaaataataatcatcataatcatcatcataCAATAATGCCACCATCAATTGGTACACCATCACCACCAATATCAACAACACCAATTGGTTCAGCATCATCTGGACCAAATGATCTCACAttgcatcatcatcatcaacaacaacaacaacaacaacttcatcatcataataataacCATCATCAACAATTACGACAACATCATGCAATGGCAATGGCATTAGCTGCAGCTGCAAGTAGACAACATTCACCACCAAATTCATTATCATCATTAAATGGTATAAATAATGGTGgtgttaatataaataataattatgatgaacatAATGGTGGTAGATCAACATCTAGTCCAGGTTCATCAACAACAATTGGTGATTTATGTGGTGTACTTGGTAATAGTGGTATTGGGTCAATGGCTGGTCCCGGTGGCCCACATTCATGTACACAATGTTCAGCATCATTTCCAACACGGGATCATTTAGAAAAACATGAGATAATGCATTCGCCAAGCTCACAAGTGTCTTGTAAAATTTGTCATAAACATTTTGCAAATGTTTATCGTCTACAACGTCATATGATTAGTCATGATGAATCGGCATTATTACGTAAATTCAAATGTACTGAATGTGATaaagcatttaaatttaaacatcaTTTAAAAGAACATGTCCGGATACATTCCGGTGAAAAACCATTCGGTTGTGATAATTGTGGTAAACGTTTTTCTCATTCCGGTTCATATTCCAGTCATATGACATCAAAAAAATGCATTAGCAtgggtttaaaattaaataataatcggTCAAtgattaaattagaaaaatcatTAACTGGTGGTAGTCCAAATTCCAAACGAAatagtaacaataataataataatggtggtggtggtggtggtagcGGAAATCATAATACCAATAATAATGTTGtaaataatacacaaaattttcaaccaaatccattaaattattttccaccTGGTCTACCAGGATTACCAAATGTAGCAGCAGCTTTAAATaataaccaaaataataataataataataatagtataaatCAAATTGGTAATGGTATACAAACAGGTCAAACTGGTAATGTTAATCCAAATGCATTTTATCcaattttaccaaaatataataattatgatgcAGCAGCTGTTAATGCTGCATTATTAGCATCATTTCATCAAAATCCATTTTATAGTATGGCTGCATTAGATCCACGTATAAATCCATACGGTATCCACAGGCTATTAGAATTATCAGCAACTGCTGCATCAGCTAATAATGCtagattaaataataattcagaTCCAGATGATATGATTGAAGAAGTTACCGAAGATGATGTCCCAGAagaaccaaaattaattatggaTTTAGAAGATAAtgatatcaataaaaatattgatgaagATGATAATGAAATGTTAAATGATCAAAATAGTCGACAAACAAATTCACCAACACATAATATTGATGAAgataatgataattatattaataatgataatattaaaagtaattcTAAATCGCCGGAAATAGAAGATATTGAAAAAactgatgataataatgataataataatattattaatgaaatgaTAATTCCAAAAACTGAACCTAGAGAAGAACAAAGTCCAATTTTAGATGACACTCATCCCATCATTAATAATTCAccgaaaattaaaattgaaacaaatcaagaaaatgatgatgaagaagaagaagaacaaACTGAAATTgatgtaaaagaaaatatattacaatgTGGACGTTGTGCTAAGAAATTTAATCATCAAACCGAATTGGTGCAACATGAAAAAGTTTTATGCGGTTTAATAAATGCTGTTGAACAACATCAAAACCAAATAACACAACAACAAACCACCGATTTAGATAATGTAAATTCATCATCATCCATTTATTTACAATCGGGtagtgatgatgatgttgaagATCATGAATCAAAAAATAGTAGTGAAAATGAACGTAAAGTTCGTGTACGGACAGCAATTACCGAAGAACAACAATCAATACTTAAAGAGCATTATGCGATAAATGCTAGACCAAGTCGTGAAGAATTCCGAATAATTGCAAATCGTTTAGCATTAGATGCTCGTGTTGTTCAAGTATGGTTCCAAAATAATCGTTCGCGTGAACgtaaaatgaataattatgtTGGATCAAATATTGGTGGaagttgtaataataaaaattttgcatCACCACTTTTGGCACAATCACCACCATCATATAGTCCATCAGTTCAATCTAATGCTGTAATTCCAAATGTAGTAACAGCTAATATTAACGGTGAAACTATAACAGATTCACGAAATAATTCCAATGAAGATCAACCATTAGATTTGTCGGTTAAACGTAGCGATCCATCTAATATTACACCAATAAATTGTTCAACTCGTTATGGACCAGTATCTATGCAACAACCATCTGATGAAGCAATTAATTTAACTAGTCGTAAAAGGAAAATATCCCGTAGTCCAAAACCATCATACGTACCACCAGCAATGTATTATGGAAATTCATCGGCACCGTCCTACAATCATCATACAAATgatattacatttataaaacGTCAAACACCATCGCCAAGTGAAACAATTCCATCAAATACAAATCGTATACAACAGCAAAATAATCCATATATTTTACCTGGTACCCGAGGTTTAGTTCCAATGGAGTGTCTCCTTCAAATGACACCAGATTATGCACGAAATCAAATAATGGGCAGTTTGAAATTAGGCGAACGTGGTACTAGTTTAAGTCCAGGTTCAGAAAAGAGATCATGGCGTGATGACGATTCACGTATTTCACATGATGATGAATATTTAATGCATGGCAATGGTAAGAGACTTAAATTGGATACAAGTGTTTCAACAAATAGCAATGGTGATTCTGATTTACCATTTGTATGTGACCAATGTGATAAAGCATTTAGTAAACAAAGTTCATTGGCACGACATAAATATGAACATTCaggACAACGTCCATACAAATGTGTTGAATGTCCAAAAGCATTTAAACATAAACATCATTTAACCGAACATAAACGTTTACATAGCGGCGAAAAACCATTCCAATGTTCCAAATGTTTAAAACGTTTTTCACATTCTGGTTCATATAGTCAGCATATGAATCACCGTTATTCATATTGTAAACCATATAGAGAGTAG
Protein Sequence: MLSCLVPRFGQEDKINMPSSTAFSLQFPSLASSLHHHNNINKNDDSSSIAAAHAASTIGGGDFIVKCPQCHQRLSGFPALREHLETEHPHEKQNYESSPNYLLPFGNFNNNNLNGIDHHHQQQQQHHHHHNNHRNSRNNNHHNHHHTIMPPSIGTPSPPISTTPIGSASSGPNDLTLHHHHQQQQQQQLHHHNNNHHQQLRQHHAMAMALAAAASRQHSPPNSLSSLNGINNGGVNINNNYDEHNGGRSTSSPGSSTTIGDLCGVLGNSGIGSMAGPGGPHSCTQCSASFPTRDHLEKHEIMHSPSSQVSCKICHKHFANVYRLQRHMISHDESALLRKFKCTECDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSYSSHMTSKKCISMGLKLNNNRSMIKLEKSLTGGSPNSKRNSNNNNNNGGGGGGSGNHNTNNNVVNNTQNFQPNPLNYFPPGLPGLPNVAAALNNNQNNNNNNNSINQIGNGIQTGQTGNVNPNAFYPILPKYNNYDAAAVNAALLASFHQNPFYSMAALDPRINPYGIHRLLELSATAASANNARLNNNSDPDDMIEEVTEDDVPEEPKLIMDLEDNDINKNIDEDDNEMLNDQNSRQTNSPTHNIDEDNDNYINNDNIKSNSKSPEIEDIEKTDDNNDNNNIINEMIIPKTEPREEQSPILDDTHPIINNSPKIKIETNQENDDEEEEEQTEIDVKENILQCGRCAKKFNHQTELVQHEKVLCGLINAVEQHQNQITQQQTTDLDNVNSSSSIYLQSGSDDDVEDHESKNSSENERKVRVRTAITEEQQSILKEHYAINARPSREEFRIIANRLALDARVVQVWFQNNRSRERKMNNYVGSNIGGSCNNKNFASPLLAQSPPSYSPSVQSNAVIPNVVTANINGETITDSRNNSNEDQPLDLSVKRSDPSNITPINCSTRYGPVSMQQPSDEAINLTSRKRKISRSPKPSYVPPAMYYGNSSAPSYNHHTNDITFIKRQTPSPSETIPSNTNRIQQQNNPYILPGTRGLVPMECLLQMTPDYARNQIMGSLKLGERGTSLSPGSEKRSWRDDDSRISHDDEYLMHGNGKRLKLDTSVSTNSNGDSDLPFVCDQCDKAFSKQSSLARHKYEHSGQRPYKCVECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00643987;
90% Identity: iTF_00643987;
80% Identity: iTF_00643987;