Este021874.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Empis stercorea
Gene Symbol
Hivep1
Assembly
GCA_949752835.1
Location
OX457088.1:24837057-24855165[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.00069 0.07 14.4 2.1 1 23 505 527 505 527 0.97
2 8 0.0024 0.25 12.7 3.5 1 21 533 553 533 557 0.89
3 8 0.029 2.9 9.3 0.1 1 20 1115 1134 1115 1136 0.95
4 8 8.5e-06 0.00085 20.4 1.1 1 23 1978 2000 1978 2000 0.99
5 8 1.7e-05 0.0017 19.5 3.9 1 23 2006 2030 2006 2030 0.92
6 8 0.00047 0.048 14.9 2.1 3 23 2588 2608 2587 2608 0.97
7 8 0.0064 0.65 11.4 0.8 1 23 2614 2638 2614 2638 0.91
8 8 0.0084 0.85 11.0 1.7 1 23 2659 2683 2659 2683 0.93

Sequence Information

Coding Sequence
ATGCTTGATATCCTAGCCACTCGTGAACATAGACcttatcaaaaaaataaatctgtgaaatcaattaaattaccaGTAACAACACCACAAAAAACATCAAcaaataaatccaaaaataCTAACATTACTAGTGGTGTTGGTGGTAATACAATCATggatgaattaaatataaaatcaacaaaattattaaaatcaactacaacagaaaaattacaattacatttattaaataatattgatataaaaaatatgaccaatcataatcatataaatcataataaaatttttaataataatcaacaacagcaaaaaaatcATCCAGcaaccacaacaacaacatcatcatcaacaaattCATTATATTCAACACCATTATCATCCACCCAAATATCTGAAAATTTAATCCACCGTAATAgccaacaacaagaaaatttaattactagTTCAACATTAGAACctaaaaatcatatttcaaataatataaataataatattgataaaattaatagtaataataataataatagaaataatgaaattttaatatcaaatattaataattgtcaATCATCAAATAGTAATAACAATGATAAGTACctgcataaaaaatttaaaagaccTGCCAGTGTCTCAGttatagataataataatgattattcAAATTCATCaattacaaaaacaacaacaaatttaattatagaaaatcatCAACAAAATAATCATCGTTTATCAATTGATTCAATTGGTGGTTATAGTGATGGTAATAGTAATAATCATAttgttataaaagaaaataatattattggtgaaaatttaaaaaataatattaataataacattaatattgTAGAAATATCGGAAAGCTTTAGTAGtgataatcaaataataaataataataataatattaataaaaataatcatatttgTGAAAATGGTCATGATGATATAATAATTggtaatgaaaaaattaataattttaataatattgaaagtgataataatgaatatcaacaacaacataaacaaaataatatattaaaaaataaaaaacaaattgtagtaaattcattatcaaaaacaattaatgataaatcaattgtgaaaaaaccaaaagttaaacattatataaaaggACCATCATTAACATATTCGggaccatcatcatcatcatcatcagataATTTAGCATTATCAACAATAGAAGCACAACAATTATTGTTGAAACAAGAAAAACAACAGCGACTATTATCAACAAGTTCAACTGAAtttcaaaaacaaacaaataataatgatattaataaaatagtaaataataataataatagaaatatttacaataataatacaaattcaacaatttcaccACCAATATCAAATAACATGCACAAtagtacaaattttaatataataaataatcaaaaattagaTAAACAAGACATAGATCagcaacaacaaataaattcaaCAACAATAGCAACAACAACTACATCTACTACTATATTAAGTGGACGTCATGTTTGtccatattgtaatttaaattgtacGAAACCTTCAGTACTACAAAAACATATCCGTGCACATACAAATGAACGACCATATCCATGTGATAAATGCGGTATTGCATTTAAAACaaatagtaattattataaGCATTGCAGATCAAGATCGCATCTTCAACGAATGAAAGGTGTTGTCGATCCCCAACCAAATGACGATGATGGTTCATTAGGTTCAGATCAGGATCCAGATTTAAGTAATAGCAGTTCCGATGTGataagTGGTACAGTATCACCTCTTGATGAACGCACATCATCACCAGCAGTACAACAACTACAACATCATAATCATTATAACCATCTTCATCACCACCACCATCAACAAAATCAATTATCTTCAGCTTCCTCAATTTCATCgaattcatcatcatcatctgtaCAAAAGAATTCAAATGATAAACCatataaaccaaaatttcataatgCTGCTCTGTATAAAGATGAAAATATAGGAACAACTACATCATTATATCATACCCGCCATCCACAACCCCAAATAccaccacaacaacaacaacaacaacaacaacagcaatctTCGATGTCGCCATATAGCAACAAGCAAAATCAAATGACAATTTTGTCGGCGACATCTAAtctacataatattaataatcacATTTCTGAGACATTATcatcaaattattattcaacTCAATCGCAATTTATACATCagcaacaagaacaacaacaacaacaaatactTCATAACCATTCAACATATATACATTCACACACTAGTGGAAAAAATCATcatgaacaacaacaacagcagcaacagcTTCATCGTAGTCAAATTTCAGTAAATTGTGAGTCAGCAATGGTGGGGTCATCAACAATACCACCCCATCATCAACAATATACACAACAAATACCATCAACTAATTTTCAACAAGCTGTGGCGCCTGCTTATAATACAGAAACTACTGGTATAACAACTATACCATTAGTTGTTAGAGATTCAACAGGTTCGAGTAATAATTTTAGTGGCGGCAATAGTGGTGGTAGTCTGGCCACAGCTACAACTGGGGGTGGACATCAATTGaatGTTGAATTTTTGCAAGAGCATATATCCAAATTGATATCACAAAATCAAGCCATAGTAGAGAATAAGGAAGTTTTATTACAAAAGAAATATccaaaacaattaaataaacaaaaaagtttatcaagCCTAGTCATACCAACATCTTCTTCCATCATAGAGACTGGTCCAAGCTTAAGTACAACACCATTAAATTCTAAACTTCAGTTAGCTTTGGCAagcaaacaacaacaacagcaacaacatcatcatcataatcatcaACAACATCAGCAGCAGCAATTACAACTTATTCTTCAGCAACAGCAGGAAATTATTAGTCGTAATTCTCAAAATATGAATGGTTTTTTAACATTTACAAGTACCACAGGATCACTGGGATCATTACCACAAACAAGAATTCATAGTGAAAGTAGCAATAAAATACATACATCAAATATGACACATCAGATTCCTTCCGAATTATCAACATCATCACAGCAACcgttaaatttatcaaaattatttgttgcGGAAATACCAGGGATAATAAATAGTTCACCATCACCACCTCTAGCGCTTGCTGTGAAGTCATCATCACGAAAACGTTCAGCAGATGATATACTTTCATCCAATAGCAACAGTACACCCACAAAAACCTTAGCTACTCATCCACAAAATCCTGAACGTtctataataaaacatttactTTTAAATGCTCGTGGTTTAGGTGTACCGAATGGTGAAGGTGATGATGCTGTTTATACATGTCCTTTATGTAAATTagattttcaaactgccgaagaATTAAAACTTCACACAAGCCAATATTGTCAAGGTGGACCATCTAGTGCCCCAATCAGTCCAGTCGCATCAccatcatataaatatttccgttcaaattcaataaatgtaaatttgcCTGAATTTAATAATCCTACATCATTGGCAACATTAGCAAAATCATCATTATTACATGGCAAAAATCCATTGCCATTAGCTAAATTAGCATTTTATcgattaaaaacaaaacaaagtaatttaatattaaatcaattaaatgtaAGCACAGGAAATTCAACAAATAATGCAATAATGTCAACATCTTTAAGTAAAAATGATGGTATTGAAACagtacaaaaattaattgatgcACCATTACCATCACCAGGACCATTATTAGGTAAAACACCACTTGTAGAATCTTATAATCCAGCTTCAAATTCAGATCATAAATCAGAAGATGTTATTATAACAAAAGTGCATGAAGAAAGAAATTTTCCAAGTACatcaaataaagaattttataatgttaAGAAAATTAAACTTGATAATCAAAACGCACTAATTAGCATTTCATCATGTAATAATTATTCACCTGCACATTCTCAATCATTTTTTGGTAGCAACATGAATTCAAATATAATGTTCGAATCTCAATCCACACAAAAACCACAATTTGTAATGTGCGGAGGTGGTGGTGGTGGCAGTGATACACAAATTGTTGATAAAAAAGATAATAGTATTAATAAACGTTTTATGTCATCTGGTGGATGTATTGAACCGATAACTGATAGTATAACAAGTCCCAAATTTTTTCGTACTCCTTTATTATCAGGTGGTAGTTTTACTGAAATAATACAACAGAACGAATCGCAGGAAAATCGTCATCAACATTCACATCAtcatcagcaacaacaacaacataaaaaacatGAACCAAATCAATTAACATCTATTCAACATGTTACACCAAAAATGATGATACCAATAACACCATTAACACCAAGTTTATCAACACCAAATATTCTTAGTGGAGGAGGATTACCATTATCTGGTCAACATTTTCAATTTCCACCAATTAATTCAATTACTGGTTTTAATCCATTGACCTTACCACCAATAAATATATCGCATTCACCAGTTTTACCAAATGGTGAAAAATTAATACCATATGTACCAGGTATACCTGGACCAAATACAATATCATTACaattaccaccaccaccacaaaTAATACTTGATTTTGCTAGTGCTAATCGTAATTCTAGTCCAAATCGTAAAAAAACTACTAGTCCATTGGTACAGGAATCTGGAACTAatgatcaacaacaacaaaattatcattatagaaattctattcaaaataaaaagtatatacaaaaaCCGATTATACGAATAGAAAATACAGAAATTAGTAGTACGCCATCAATTTTGCAAATATCACAAAATGATTTAACTGCTAATAATAGAATATATCGTTCTGTAGATGAATCATTTCAGCAACAACCTCAACGTAGTCCAAAAATGGGTTCAGTATGGACACCGAATAGTATTGTTGAAACACCATCTCAAAGAAAACCATTTAATTTTACACGTATGGCTGATAATATTAGTCCgaaaaaacctgaaaaaaataatttaataaaatctctCTCTGTAAAAGAATCAagacattttaattttgaaaatttaagtacAATTAAAACAGAAATCAAAACTGAAGATCTACAGCCGCTACATGTCGATTGTCCATCAACAGCAACATTAACAGTAGTGccatcatcatcaatatcaaAAAATTCACTATTAGAAACTTTACCACCACTACAATCACCACAAAATACTGATGAAAAATTATCTGCATCTGTTTCTTctacaaaaaagtcaaaattcTTACGACCAACAAGTTTGCCATTAAAACCTGGAACTTTTACACCAAAACGTCATCATGGCATAACACCAACAGCAAATACAATGCCATTAATTTCACCAGAAACACCAAGACCATCAAAAACATGTGGACAAATGTTTCTTAATGGTCATGCATACACTTATTTGGGCTTAAAATGTagtacaaaaatgttttattgtaCAGTTAATTGCCCTCAACCATCATATGTTGCAAATTTACATAAACTCTCTATGTATAGTGTTTGGCAAGTACAAGCTGAGAAAAATCTTCATCCACTTGGATTGAAACCAAAGACAGTAATGGCATTGTATGATTCACGACAACGTAATTGTACTGGATTATCAATGGCTAATATTAAATTACCTTATACATCAGTACATTCACAGCATACTGTAATGACACCATTTGAAAATAATACTGGTCAATTTTATCATCATCAAATCAAATCTGTACCATTATCTCAATTGACAAATAAAACAACGACATTGTCTGGATCATTGCAGCAGCAGGAACAAATTATTGTTACTAATGTTACTGGTACAAATAATACTGTTAATACTGTTAAAGTTACAGATAACCAAAAAGGACCAATTTTAGTTGGTGGCTATGAAAGTAACGaagattatacatatattagagGTAGAGGGAGAGGAAAATATGTTTGTTCTGAATGTGGTATTCGTTGTAAAAAACCCTCAATGTTGGTGAAACATATAAGAACCCATTCAGATATTAGACCGTATACATGTTTGCATTGTAATTTTAGTTTCAAAACAAAAggaaatttaacaaaacataTGCAATCCAAAGCtcattataaaaaatgtcttgAATTGGGTGTTGATCCTGGTGAAGGGTTGAATGGTGAATTTGTAGATCGTGAAGGTGATAATGATCAGCAATCTATAACATCTGGTAATGATAGAACGTCTTCTATTCCCGGTGAATCAGATTCAGAATATGGAAGTGATGGAGAAGATCGTGAAACTGAAAGTAGtgatACCGATGAATCAAAATCTCGTTTACCTGAACATGAGGCTGCTCATTGTCTATTATCATTATCAATGACACCACCAAGCAGTAGTATATCACCGCATTATCGTTCTGTttctcaattaaataattatgataatgaaaaacatcaatcaacaacatcatcaaaTAATCGTttagaagaattaaaaaatcaacaaaatattgcTGCACGACGTGTTATCTCATTTACGTCACCAAAACCACCATTTGATTatcaaaaacaagaaaaatattattcaaatccAATAATTGTATCAAAAAATCGACCAATAGAAAAATTCGATGAAAATGTAATGAAACCAATTGATTTAACTAAACCACGTTCCCAACAAATACCAATTGTTCAACAGCTATTAGAAACAAATCAAACTCCAACATCAAAACAAACTGGTGAGAATCCAAAAATTACTGATGTCATTGGTAATTTGTCAAATGAATCTGTTTTTCATAAATCTTTACTTTCCATAACGGATAAAATAAGAGTTGGTGGCAATACAGACTCAATTGAATTTACTGGACATCATAATCATCATTCGCAGAAACAAAATGATGATATACTTTTCCAAGCATATCTAACGGAACAAGCATTACAATATACGAAAATAAAACAAAGCCAAATGAgtagtaaaagttttaattCAGATGATATAATTAAAACAGGTATTGGTGTAATTGTTACAACAACTTCAACTACTTGTGGTGTGggcaatttatattataataataaaaatataggaaaagataatataaatagtaaatcacaaaatttaacaataattacaGAAACAACAACTACACAATCATCGAATTCACCAATCATTTCGACAACGTTAgtaacaaattcaaatttatctaACAATTTGAATGaagataaattagaaaatatgaaaaatgacaCAACAACAATATTATCATCACATATAATAAACCAAAGTACAATTAAAGAAGTTGGTTTAGATATGCCTAGAATTACAGAAAGTCCTGTTgctattgaattattaaatgacgcaaatttgaaatcaaataaaagtaatattaaggAAAATAACGAATCGTCATCGTctttaaaaatagtaaatgaaAATTCTCAAATAATTCGAACTTCATCAATGTCGAAACAACAAGATAATGCTAAAAGTGTTGCTtcggaatatttaaaaatgacacAAAAGACAAATAATAACTCTAATAATTCAGGTAAATTACAAACTGAAGAAAATCTAGATGAAGAAGATAGTTCAGATCAAGAAATTTTATCAACTACCAATATTACAAATACTACAACAACATTGACAGATAGTAGTAATGTAAAGGGTTCTACTGATTTTAGTGGTATTCTAGCACGTACTGTAATTGTTGGTGAAGATggttttaaaaaatcaacaacaacagcagataatcagaaaatatttaatcgTGTTCCAATTTCTGATGATAATGGTCGACCAATTTGTACAATTTgtacaaaaacttttcaaaaacaACATCAACTTGTGTTACATATGAATATCCATTATATGGAACGTAAATTTAAATGTGAACCGTGTGCTGTTAGTTTTCGTACACAGGGACATTTACAAAAACATGAACGTTCCGAAGcacataaaaataaagtaatgaTGACATCAACATTTGGTGTACCAACAACATCAAATCCACGTCCATATGAATGTGCTGATTGTAAAGTAGCATTTCGTATTCATGGTCATTTAGCAAAACATTTAAGATCAAAAACTCATGTACAAAAATTAGAATGTTCACAAAAATTACCATTTGGTACTTATGCAGAAATTGAAAGAGCTGGTATTAGTTTAACAGAAATTGATACAACTGATTGTGATAATTCGTTAgctagtttaaaaattttagctcaaaaattatttgaaaaagatCCAAGTAAATTGTCCGCATATACAAAACCATCTGGTATGGAAatcaattcaaatataataGATAATAATTGTGAAAGTGGTAGTGAAGATAATCCAGATGGTTTAGATGAAAATCAATCATCAGGAATAggattaacaaatttattagatGATAATGTTGAGAATCGAATAACTAATAACACAATAATATCATCTGGTAGTAGTAGTGGtggaattaaaagaaaatatgattCATTTAGTAGTTGTAGTAATGATTCAACGATATTATCTAATGCTGTAACTGGTGATAATAGAATAAATTCTACAACATCTACTATAATAGGTCAAGATAGTGGAAGTAATAGTAATGGTGGCGATGAAAAACGCTTGCGTTctacaaatttaacaaaataa
Protein Sequence
MLDILATREHRPYQKNKSVKSIKLPVTTPQKTSTNKSKNTNITSGVGGNTIMDELNIKSTKLLKSTTTEKLQLHLLNNIDIKNMTNHNHINHNKIFNNNQQQQKNHPATTTTTSSSTNSLYSTPLSSTQISENLIHRNSQQQENLITSSTLEPKNHISNNINNNIDKINSNNNNNRNNEILISNINNCQSSNSNNNDKYLHKKFKRPASVSVIDNNNDYSNSSITKTTTNLIIENHQQNNHRLSIDSIGGYSDGNSNNHIVIKENNIIGENLKNNINNNINIVEISESFSSDNQIINNNNNINKNNHICENGHDDIIIGNEKINNFNNIESDNNEYQQQHKQNNILKNKKQIVVNSLSKTINDKSIVKKPKVKHYIKGPSLTYSGPSSSSSSDNLALSTIEAQQLLLKQEKQQRLLSTSSTEFQKQTNNNDINKIVNNNNNRNIYNNNTNSTISPPISNNMHNSTNFNIINNQKLDKQDIDQQQQINSTTIATTTTSTTILSGRHVCPYCNLNCTKPSVLQKHIRAHTNERPYPCDKCGIAFKTNSNYYKHCRSRSHLQRMKGVVDPQPNDDDGSLGSDQDPDLSNSSSDVISGTVSPLDERTSSPAVQQLQHHNHYNHLHHHHHQQNQLSSASSISSNSSSSSVQKNSNDKPYKPKFHNAALYKDENIGTTTSLYHTRHPQPQIPPQQQQQQQQQQSSMSPYSNKQNQMTILSATSNLHNINNHISETLSSNYYSTQSQFIHQQQEQQQQQILHNHSTYIHSHTSGKNHHEQQQQQQQLHRSQISVNCESAMVGSSTIPPHHQQYTQQIPSTNFQQAVAPAYNTETTGITTIPLVVRDSTGSSNNFSGGNSGGSLATATTGGGHQLNVEFLQEHISKLISQNQAIVENKEVLLQKKYPKQLNKQKSLSSLVIPTSSSIIETGPSLSTTPLNSKLQLALASKQQQQQQHHHHNHQQHQQQQLQLILQQQQEIISRNSQNMNGFLTFTSTTGSLGSLPQTRIHSESSNKIHTSNMTHQIPSELSTSSQQPLNLSKLFVAEIPGIINSSPSPPLALAVKSSSRKRSADDILSSNSNSTPTKTLATHPQNPERSIIKHLLLNARGLGVPNGEGDDAVYTCPLCKLDFQTAEELKLHTSQYCQGGPSSAPISPVASPSYKYFRSNSINVNLPEFNNPTSLATLAKSSLLHGKNPLPLAKLAFYRLKTKQSNLILNQLNVSTGNSTNNAIMSTSLSKNDGIETVQKLIDAPLPSPGPLLGKTPLVESYNPASNSDHKSEDVIITKVHEERNFPSTSNKEFYNVKKIKLDNQNALISISSCNNYSPAHSQSFFGSNMNSNIMFESQSTQKPQFVMCGGGGGGSDTQIVDKKDNSINKRFMSSGGCIEPITDSITSPKFFRTPLLSGGSFTEIIQQNESQENRHQHSHHHQQQQQHKKHEPNQLTSIQHVTPKMMIPITPLTPSLSTPNILSGGGLPLSGQHFQFPPINSITGFNPLTLPPINISHSPVLPNGEKLIPYVPGIPGPNTISLQLPPPPQIILDFASANRNSSPNRKKTTSPLVQESGTNDQQQQNYHYRNSIQNKKYIQKPIIRIENTEISSTPSILQISQNDLTANNRIYRSVDESFQQQPQRSPKMGSVWTPNSIVETPSQRKPFNFTRMADNISPKKPEKNNLIKSLSVKESRHFNFENLSTIKTEIKTEDLQPLHVDCPSTATLTVVPSSSISKNSLLETLPPLQSPQNTDEKLSASVSSTKKSKFLRPTSLPLKPGTFTPKRHHGITPTANTMPLISPETPRPSKTCGQMFLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVANLHKLSMYSVWQVQAEKNLHPLGLKPKTVMALYDSRQRNCTGLSMANIKLPYTSVHSQHTVMTPFENNTGQFYHHQIKSVPLSQLTNKTTTLSGSLQQQEQIIVTNVTGTNNTVNTVKVTDNQKGPILVGGYESNEDYTYIRGRGRGKYVCSECGIRCKKPSMLVKHIRTHSDIRPYTCLHCNFSFKTKGNLTKHMQSKAHYKKCLELGVDPGEGLNGEFVDREGDNDQQSITSGNDRTSSIPGESDSEYGSDGEDRETESSDTDESKSRLPEHEAAHCLLSLSMTPPSSSISPHYRSVSQLNNYDNEKHQSTTSSNNRLEELKNQQNIAARRVISFTSPKPPFDYQKQEKYYSNPIIVSKNRPIEKFDENVMKPIDLTKPRSQQIPIVQQLLETNQTPTSKQTGENPKITDVIGNLSNESVFHKSLLSITDKIRVGGNTDSIEFTGHHNHHSQKQNDDILFQAYLTEQALQYTKIKQSQMSSKSFNSDDIIKTGIGVIVTTTSTTCGVGNLYYNNKNIGKDNINSKSQNLTIITETTTTQSSNSPIISTTLVTNSNLSNNLNEDKLENMKNDTTTILSSHIINQSTIKEVGLDMPRITESPVAIELLNDANLKSNKSNIKENNESSSSLKIVNENSQIIRTSSMSKQQDNAKSVASEYLKMTQKTNNNSNNSGKLQTEENLDEEDSSDQEILSTTNITNTTTTLTDSSNVKGSTDFSGILARTVIVGEDGFKKSTTTADNQKIFNRVPISDDNGRPICTICTKTFQKQHQLVLHMNIHYMERKFKCEPCAVSFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPYECADCKVAFRIHGHLAKHLRSKTHVQKLECSQKLPFGTYAEIERAGISLTEIDTTDCDNSLASLKILAQKLFEKDPSKLSAYTKPSGMEINSNIIDNNCESGSEDNPDGLDENQSSGIGLTNLLDDNVENRITNNTIISSGSSSGGIKRKYDSFSSCSNDSTILSNAVTGDNRINSTTSTIIGQDSGSNSNGGDEKRLRSTNLTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-