Basic Information

Insect: Empis livida
Gene Symbol: ZFX
Assembly: GCA_963932195.1
Location: OZ010647.1:1163857-1166701[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.2 12 6.8 0.1 1 23 241 263 241 263 0.97

2 10 0.0037 0.22 12.2 1.1 1 21 268 288 268 292 0.92

3 10 0.81 49 4.8 0.2 1 12 329 340 329 352 0.88

4 10 4.5e-05 0.0027 18.2 6.5 1 23 358 381 358 381 0.96

5 10 2.5 1.5e+02 3.3 0.4 1 23 387 409 387 409 0.87

6 10 1.1e-05 0.00069 20.1 2.9 1 23 419 441 419 441 0.97

7 10 2.8e-05 0.0017 18.9 1.2 1 23 447 469 447 469 0.98

8 10 0.011 0.69 10.7 1.0 1 23 475 498 475 498 0.96

9 10 0.00014 0.0084 16.7 1.9 1 23 509 531 509 531 0.96

10 10 4e-05 0.0024 18.4 1.6 5 23 540 558 537 558 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.2	12	6.8	0.1	1	23	241	263	241	263	0.97
2	10	0.0037	0.22	12.2	1.1	1	21	268	288	268	292	0.92
3	10	0.81	49	4.8	0.2	1	12	329	340	329	352	0.88
4	10	4.5e-05	0.0027	18.2	6.5	1	23	358	381	358	381	0.96
5	10	2.5	1.5e+02	3.3	0.4	1	23	387	409	387	409	0.87
6	10	1.1e-05	0.00069	20.1	2.9	1	23	419	441	419	441	0.97
7	10	2.8e-05	0.0017	18.9	1.2	1	23	447	469	447	469	0.98
8	10	0.011	0.69	10.7	1.0	1	23	475	498	475	498	0.96
9	10	0.00014	0.0084	16.7	1.9	1	23	509	531	509	531	0.96
10	10	4e-05	0.0024	18.4	1.6	5	23	540	558	537	558	0.95

Sequence Information

Coding Sequence: atgGAAGAAGTGCGGTGTAGTTTATGTGctgaacaaaataataataattatcaattagATAATGagttaatagaaaaaattaactttaatttaccAGTAAAGgtttttaaaGGCACAATTTGTGTCGGATGTCACTTACAATTAGAGTCAACTATAGAATTTTTCGATTTAATTCGTAATGGCCAAGTTATTCTAGAAGATATTGAAAGTAAATCTTTCccgaaagaaaattatattgaagaaTTTATACCATCTGCAGAAATAGTAGAAATTGATTATTCTCCATCATCATCACAACCTGCCACTGATAATATTTCGGATACAGAACAATCTAATAATGAGAcatcacaaaatatttctaaaaataattcaattctaagaattaataataataataatttcaattcaattaaagCAAACCTATATGATATTTCATATAGTAATAAACgaagagaaattaaaaaaccaatttgttataaaaataatcaatttgaaGGAGAAgagttaagaaaattatatattaattatggtATATTAGATGAAACggatttaacaaattttgatttggACAATAATAATGCAgattcaaatgaaaaaataattggttTTATTGAAAGTAATGGAGAAAATATTGCTGATATTATTAAAGGACCTTCACCTAATGAATATAAAGAACtgaatgataataaaaaaattacaagaaaatatcaaaaaactcattttatttgtgatgtttgtaaaattagattaccaaatgaattaaaattattagaacatcgtttaacacataaaaatgttttatatgaaTGTACAGAATGTCAAGAAACTTTTGATATACGTGATAAACTTTTTCATCATCAAACCGAATTAGTACATAACGGTCAAggtattattgaaaattttactgatttgACACagcaaaaaacagaaaatttagaGCTTAAAAATTCCACAACAGAAGAAGATATTCATAATTCTGAAGTATATAGTTGTAAAGAATGTGAtatagaatttgaaaatatgataGAATCTgataatcattttcaattaacacATAGtgataaatatacatatttttgtagtatatgccataaaagttttaaatataaattaaatctacaACGTCATCACAAAATAGTACATTCTAGTTTACGTCCATATATGTGTCGATATTGTGGAATTTATTTAGCTacAAAATTAACGGCTGATAATCATGAAAAATCTCATATTAATGAAgattttgttagaaaaatatttacatgcAAATTGTGTAACAAAATCTTTGAGTACAATAGTAGTTTTAAACGACATATGGAACAACATGCAAATAAAAGACCATTTAGTTGTGCAatttgcttaaaagtttttcgccaaaaaatacatttaattgaaCATGAACGCACCCATACAGgtATTAAACCGTTTGAATGTGATAAGTGTGGTGATAAATTTGCCACATATTCTCAACGTCGAGCTCATAAAATCCGATCACATtcattaaatgttattaaaaagaatataaattatttatgtacaatatgtggtaaaaatttatgtagtaaAGAAGCATTACGTAAACATAATCGTATACATACGGGTGAAAAACCATATAAATGTGATTGTGGACACAATTTTTCTGATCCATCAAATTTACGAAAACACatcttaaaacataaaaaagataaatctaaatttgaaataataaatacaaataatttagatgatatagtacaacatatttttggtacagataataatgaaaataatttagttgaaGAAATAATCGAAATTCATGAGAATAATTTAGTTGAAcgaataatagaaaataatacgattaatcaaaatataagaaatattgaaGTAGATTTCGGTGAACAACTGGAaagtaatgaaataaatatagttgaacaaataatagataataatcaatataatttaaatcaagaaattttaaataatgataataataatggaaatatattagttgatcaaattttacaaaataacgaaaataatttatgtgaacaaattataaaaaattgtgaaaataatgaaattatgaataaattaatttatattaatggtGAACGTAATTTAATATGTGATAATACATTTGacggaaattttgaattaaatttaaattttttataa
Protein Sequence: MEEVRCSLCAEQNNNNYQLDNELIEKINFNLPVKVFKGTICVGCHLQLESTIEFFDLIRNGQVILEDIESKSFPKENYIEEFIPSAEIVEIDYSPSSSQPATDNISDTEQSNNETSQNISKNNSILRINNNNNFNSIKANLYDISYSNKRREIKKPICYKNNQFEGEELRKLYINYGILDETDLTNFDLDNNNADSNEKIIGFIESNGENIADIIKGPSPNEYKELNDNKKITRKYQKTHFICDVCKIRLPNELKLLEHRLTHKNVLYECTECQETFDIRDKLFHHQTELVHNGQGIIENFTDLTQQKTENLELKNSTTEEDIHNSEVYSCKECDIEFENMIESDNHFQLTHSDKYTYFCSICHKSFKYKLNLQRHHKIVHSSLRPYMCRYCGIYLATKLTADNHEKSHINEDFVRKIFTCKLCNKIFEYNSSFKRHMEQHANKRPFSCAICLKVFRQKIHLIEHERTHTGIKPFECDKCGDKFATYSQRRAHKIRSHSLNVIKKNINYLCTICGKNLCSKEALRKHNRIHTGEKPYKCDCGHNFSDPSNLRKHILKHKKDKSKFEIINTNNLDDIVQHIFGTDNNENNLVEEIIEIHENNLVERIIENNTINQNIRNIEVDFGEQLESNEINIVEQIIDNNQYNLNQEILNNDNNNGNILVDQILQNNENNLCEQIIKNCENNEIMNKLIYINGERNLICDNTFDGNFELNLNFL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -