Basic Information

Insect
Empis livida
Gene Symbol
-
Assembly
GCA_963932195.1
Location
OZ010649.1:11687704-11689383[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 4.1e-05 0.0025 18.3 1.1 1 23 223 246 223 246 0.96
2 8 0.0014 0.084 13.5 4.2 1 23 256 278 256 278 0.96
3 8 1.7e-06 0.0001 22.7 3.1 1 23 285 308 285 308 0.98
4 8 0.001 0.062 13.9 0.3 1 23 314 336 314 336 0.97
5 8 0.00011 0.0067 17.0 4.1 1 23 342 364 342 364 0.98
6 8 0.00041 0.025 15.2 0.2 1 23 369 391 369 391 0.97
7 8 0.00034 0.02 15.5 1.8 1 23 397 419 397 419 0.97
8 8 0.0089 0.54 11.0 4.3 1 23 425 448 425 448 0.97

Sequence Information

Coding Sequence
atgttaaatgaatGGCAAAAATGGTGTCGTTTATGCGCCaaagaaaatggaaatattattgatgTTTTAGTTAAAGATGagaatattatgaatttagcAGAAATAATACAAAGAATTTTCTCTATTGAAGTTGTTTCTACTGATGGAATTTCTACAACAATTTGTTTAGATTGTCACAAATTTATatcagaaattgtaaatttttctgaaCGTTCATCTAGAGTTCAATCAATGTATTCGGAATTGAAATTTAGTTCAAATTTGGGTACAGTTAGGATTGATTTATATGCTTTACGCCAACAATTTGGtattttatcacaaaaaaaatatgataaaaataaattaatatcacaAAGTACTGatatcaataatttacaaCAGAATTTAGTTAGCCAAAAAGAAGAATTTAACGCACAAAAAATAACGAACgaaattgttaatatattagattttaaaaatattattgatcatgatgataatgatgatgacgATGATATTACAGAAATAGATTATCTTCATGgagatttattagaaattacacatgaacaacaattaaataatgatgaaaattctAAAGATAATAGtatagaattgaaaaaaagaaaaatctcaactagaagtaaaaaagaaaatcataaaaatttcgaaattcataataaaactGAATATGAATGTGAAATATgtgaaaaaagatttatacgtgaaagaaattatctttatcatatgaaatttattcataataaaaataataataatgataataaattttcatgtaataaatgtaataaaaaatttcaatcaaaaaaacGTTTAACAGATCATACAGAAAACCATATACATCCTGAAATAACATATCAATGTCCATTTTGtgataaaagttttacaaaaagaGTTTATTTACATTCACATGTTCGTACAATACATGAAAGTATTAAACCATATATTTGTGAAGAATGTGGTAAAGCattaggtTCTTGTGGAGCATtaaaagaacataaatatACACATATTGATGATACACCATATCATTGTACACAatgtccaaaaaaatttaaaaataaagctCGACTcaagATACATACAGATACTCATAATGATACCGCGTATGTTTGCACAATATGTGGACAACAATTGAATACGAGACGTACACTTTTAATGCATATGGTCATTCATTCGGatcaaaaaaatcataaatgtaatttttgtggTAATGAATATAAACGCGCTAAagcattaaaaaatcatttaattttacattctGGCCTGAGACCATATTCATGTCCATTTTGTGAAAAAACATTTGCGAATGGTTCAAATTGTCGTACTCATAAAAAGAAATCACATCCAAATGAATTGGCTGCTTTAGAAGCAAGTGGTGAAAAATGTAATACTACTAATATACCAAAATTGAAACAATTAAAATCAGtgttagtaaaatattaa
Protein Sequence
MLNEWQKWCRLCAKENGNIIDVLVKDENIMNLAEIIQRIFSIEVVSTDGISTTICLDCHKFISEIVNFSERSSRVQSMYSELKFSSNLGTVRIDLYALRQQFGILSQKKYDKNKLISQSTDINNLQQNLVSQKEEFNAQKITNEIVNILDFKNIIDHDDNDDDDDITEIDYLHGDLLEITHEQQLNNDENSKDNSIELKKRKISTRSKKENHKNFEIHNKTEYECEICEKRFIRERNYLYHMKFIHNKNNNNDNKFSCNKCNKKFQSKKRLTDHTENHIHPEITYQCPFCDKSFTKRVYLHSHVRTIHESIKPYICEECGKALGSCGALKEHKYTHIDDTPYHCTQCPKKFKNKARLKIHTDTHNDTAYVCTICGQQLNTRRTLLMHMVIHSDQKNHKCNFCGNEYKRAKALKNHLILHSGLRPYSCPFCEKTFANGSNCRTHKKKSHPNELAALEASGEKCNTTNIPKLKQLKSVLVKY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-