Eliv008490.1
Basic Information
- Insect
- Empis livida
- Gene Symbol
- Prdm2
- Assembly
- GCA_963932195.1
- Location
- OZ010647.1:7376667-7378625[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00082 0.05 14.2 2.3 1 23 120 142 120 142 0.98 2 11 2.4e-06 0.00014 22.2 0.4 1 23 148 171 148 171 0.96 3 11 4.8e-05 0.0029 18.1 1.1 1 23 177 199 177 199 0.98 4 11 5.7e-06 0.00035 21.0 0.3 1 23 205 227 205 227 0.98 5 11 3.1e-06 0.00019 21.9 0.9 1 23 233 255 233 255 0.98 6 11 0.0002 0.012 16.2 1.8 1 23 261 284 261 284 0.93 7 11 0.23 14 6.5 6.5 1 23 290 310 290 310 0.98 8 11 3.1e-05 0.0019 18.7 1.9 1 23 316 338 316 338 0.98 9 11 4.8e-05 0.0029 18.1 1.3 1 23 344 366 344 366 0.99 10 11 0.0022 0.13 12.9 0.8 1 23 372 397 372 397 0.89 11 11 0.45 27 5.6 0.6 1 16 403 418 403 421 0.82
Sequence Information
- Coding Sequence
- ATGGACAGTAAAGATGATAGCCATAGTATAATATCTGCTAATGATAGTGCAATTTCATTATCAGAAGGATCCGAAATATTATCGGGTAAAAATTCatcaattaataatgaatttgattcaacattaattaaaacatcACGTCGTAGTTCTCGTATAtcaacaacatcatcatctACTATAAGCAATTTATCAAAGGTTTCAGTAAAAAATTCTGATTTAActggtaaaataattttaaatccattaacaacaacaactgaacaaactgaaaatttacatcagtttgatcaaaaaaatttaaataaaaatatagaaattaataaacgacaacgtaaaacaaaaaaaccacgTAAACAATATATTTGTCATGTTtgtgaaaaacattttttaggTTCCAGTGATTTAcgtaaacatttattaatacatTCAGATGAAAGACCATTTGAATGTGAACAATGTAATAAGAAATTTCGTCAAGCtgtatcattaaaaaatcatattgcATCGATACATGGTATTGGTGAAAAATATCCATGTACCCaatgtaaaaaaacatttccaatTAAGGAACGTTTAAGACTTCATATGCGTTTACATTCTGGTGAAAAGCCATATAGTTGTGATCGATGCCCAAAAACATTTGCACGTGGTGGTCAAttaCGTCAACATATGGTAACACATTCTGgtgttaaaaaatatccatGTGAAAATTGCTCAGCTACATTTTCAACACGATCAAATTTACGACTTCATCTAAAAAACCATAgtgaaaatatacaatttcttTGTCATATTTGTCAAAAAACATTTACCCGTGCTGAAATTCTTCAACGTCATTTAGATTCTTATCAtgctaatataaaaaaatttcgttgtgaaatatgtcaaaaaactttaaaaggaCATTTTCATCAACATATGAGAAgtcatgaaaatattaaatcattttcatgtGAAATATGTGATGctgaattttcacaaaaatgtcaattaaatGTACATTTTAGAATGCATTCAGGCGAAAGACCATATCGTTGTAGGGTTTGCTGGCAGGCCTTTGCTCATTCAAGTgttcttaaattacatatacgTAAACATACGGGTGAAAAACCATTTCCatgtttattatgtaaaaatgatGTAGCTTTTTCACAATTAGCTCATCTAAAAACTCATATGCGCACAATccataaacaaattaaaccaTATATGTGTAAAGGttgtaatgaattttttaaaattaaattagatttacaATTTCATTCAGTTGATtgtaatcaattaattaaattaaatgataataatcttgataatgatgataaaattattcttgatgatattgataatgatgataataatatacataaacaaaaaattttaaatgaattatcaaaattacgATTATTAATTGCAGttgtattaaagaaaatatcaacTGATGAACGTTTAAAGAAATTaggttttgaaaaacgtttaattGATAATGTTATTGTATCAGCATTAAAATCAGCTAATCGAAattatattgataataataataatgaatttaatgaatatgaaaaattaaaaatgaatattgaagaatttttaaaatggacAATACCAGAAGgtgtattagaaaaatttcaagaagaaaaattatcaataattgaTATATTAGAATGTATTGCtacattttattcaaaaaattcgaatttaatttaa
- Protein Sequence
- MDSKDDSHSIISANDSAISLSEGSEILSGKNSSINNEFDSTLIKTSRRSSRISTTSSSTISNLSKVSVKNSDLTGKIILNPLTTTTEQTENLHQFDQKNLNKNIEINKRQRKTKKPRKQYICHVCEKHFLGSSDLRKHLLIHSDERPFECEQCNKKFRQAVSLKNHIASIHGIGEKYPCTQCKKTFPIKERLRLHMRLHSGEKPYSCDRCPKTFARGGQLRQHMVTHSGVKKYPCENCSATFSTRSNLRLHLKNHSENIQFLCHICQKTFTRAEILQRHLDSYHANIKKFRCEICQKTLKGHFHQHMRSHENIKSFSCEICDAEFSQKCQLNVHFRMHSGERPYRCRVCWQAFAHSSVLKLHIRKHTGEKPFPCLLCKNDVAFSQLAHLKTHMRTIHKQIKPYMCKGCNEFFKIKLDLQFHSVDCNQLIKLNDNNLDNDDKIILDDIDNDDNNIHKQKILNELSKLRLLIAVVLKKISTDERLKKLGFEKRLIDNVIVSALKSANRNYIDNNNNEFNEYEKLKMNIEEFLKWTIPEGVLEKFQEEKLSIIDILECIATFYSKNSNLI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00644420;
- 90% Identity
- -
- 80% Identity
- -