Basic Information

Insect
Empis livida
Gene Symbol
-
Assembly
GCA_963932195.1
Location
OZ010647.1:14220300-14221346[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 4.7e-07 2.8e-05 24.5 1.4 3 23 11 31 9 31 0.97
2 12 6.3e-06 0.00038 20.9 1.1 1 23 37 59 37 59 0.98
3 12 1.3e-05 0.00081 19.9 1.1 1 23 65 87 65 87 0.99
4 12 1.7e-05 0.001 19.6 2.5 1 23 93 115 93 115 0.99
5 12 4.3e-07 2.6e-05 24.6 1.4 1 23 121 143 121 143 0.98
6 12 4.9e-07 3e-05 24.4 1.6 1 23 149 171 149 171 0.98
7 12 0.025 1.5 9.6 1.7 1 23 177 199 177 199 0.97
8 12 4.9e-06 0.0003 21.2 3.5 1 23 205 227 205 227 0.98
9 12 0.021 1.3 9.8 5.5 1 21 233 253 233 255 0.94
10 12 0.0028 0.17 12.6 1.1 2 23 261 282 260 282 0.96
11 12 0.00044 0.027 15.1 2.2 1 21 288 308 288 309 0.92
12 12 1.6e-07 9.9e-06 25.9 0.7 3 23 316 336 314 336 0.96

Sequence Information

Coding Sequence
ATGACACATACTGGTGAAAAACCATATGGATGTCAAGATTGCTCGAAAACATTTCGTACAAAATCACAACTAACACAACATCAACTCATTCATACTGGTGAGAAACGATATCAGTGTCCAGTTTGTcaaaaatgttttggtttaCGATCTGCCCTTGTTAGACATAATCGTGTCCACACAAAAGAGAAACCATACAAATGTGATACATGCGAAAAGGCATTTTCATCTGGCGCTCATTTAGTAGTTCATAAAAGAAGTCATACAGGTGAAAAACCGTATCGTTGTGATGAATGTCCCAGAACATTTGCATTTAATACAtgtttaattatacataaacgAACCCATAGtggtgaaaaattatatcaatgtGATGAATGTGGCAGATCATTTTCACATAGTACTGGACTTCGAATACACAAAGCAACTCATTCTGGTATTAAGCCATATTCGTGTGATCaatgtgataaaaaattttcacaattaccTAATTTGACACGTCATAAATTAACTCATACTGGTGAGAGACCACATTATTGTGATATATGTGGTGGATATTTTCGAGAtaggacaattttaaattatcataaacgAATTCATACTGGTTATAAACCACATAAATGTACAGTTTGTAATAgagaatttattaagaaatctGATTTAACCGTTCATACAAGAAGGCATACTGGCGAGAAACCGTTTAGTTGTCCAATTTgtcaaaaaacatttatatgcAGTTCATATTTAGCAACACATAAACGCTGTCATATTAAGGATAATTTAGAGTGTGATATTTGTGGTAAAATATTTGCTTGcgataattatttacaaaaacataaacttacACATGAGACACGTAAATCACATAATTGTGATATTTGTGGTGAAACTTTCCGAATTGCATCACATTTATTGAATCATAAATGTAGTGGTGAAAAGGATCTTGCTTGTGAGATATGTGGTAAAAGATTTgcaaatagtaaaaatttaagaaaacatCGAGATACCCATACAGCAGAAACAATATTACCAACttttgaaactttttaa
Protein Sequence
MTHTGEKPYGCQDCSKTFRTKSQLTQHQLIHTGEKRYQCPVCQKCFGLRSALVRHNRVHTKEKPYKCDTCEKAFSSGAHLVVHKRSHTGEKPYRCDECPRTFAFNTCLIIHKRTHSGEKLYQCDECGRSFSHSTGLRIHKATHSGIKPYSCDQCDKKFSQLPNLTRHKLTHTGERPHYCDICGGYFRDRTILNYHKRIHTGYKPHKCTVCNREFIKKSDLTVHTRRHTGEKPFSCPICQKTFICSSYLATHKRCHIKDNLECDICGKIFACDNYLQKHKLTHETRKSHNCDICGETFRIASHLLNHKCSGEKDLACEICGKRFANSKNLRKHRDTHTAETILPTFETF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-