Basic Information

Gene Symbol
HINFP
Assembly
GCA_947532085.1
Location
OX383952.1:3480219-3481592[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 1.1 86 4.7 0.4 3 23 189 210 187 210 0.91
2 9 0.00018 0.014 16.7 2.5 1 23 231 253 231 253 0.98
3 9 0.0012 0.092 14.1 0.1 3 23 259 279 257 279 0.96
4 9 0.00013 0.01 17.1 0.1 1 23 284 307 284 307 0.91
5 9 0.6 46 5.6 0.5 2 23 314 336 313 336 0.92
6 9 0.00074 0.057 14.7 1.5 1 23 343 366 343 366 0.95
7 9 0.0017 0.13 13.6 3.9 1 23 372 394 372 394 0.98
8 9 3.2e-07 2.5e-05 25.3 3.8 1 23 400 422 400 422 0.98
9 9 2.7e-06 0.00021 22.4 6.4 1 23 428 450 428 451 0.96

Sequence Information

Coding Sequence
ATGATTATTTTTCTATTTTTAGGTGACCGATCGAAAATAAAGATAAAACCTACTCGGACAAAAACAATAACTATAAAGAAGACGCCTCACATAAGCGAGAAGGATCTGCTTCAAAATTCACTATTGATTAAAAAAGAGTTTTTACCAACGGGAGATGTGTCTTTGTCCAATTCAGTAGATTTTAAGGACGAAACTTTGGTAACTGTAAAGGAAGAGCACGTAGATTCAGCGGACAATGAATACGCTGCTACCGTAAGGTCAATAACTATTAAAAAGAAGAAGAAACTGATGGTAATTCCCACTAATAGAATGATAATGAAGCCGCTACCAGCAAATACTACtaggaagagtgctataacactgttaagggacacaactctttgcccattcaaatttaatcaagggtcgtttcaatgcttttactgcacggatttatttttaaacattaaacaggtagaggaacacgttacggaacacgatgcgctaacaaaagatgatatttacaaagttctggtgagaaagtcgacgtcagatcttataaaactcaacgttcgcgaatatggttgcaaaatttgtaatgatacatctgagaatttgaatgctttaaagcaacacttgacagataaacatgggcttagattcaatcccgaaagtgacggtgtagctctttataagatagacgaagataaatttgaatgcgcgcattgcactaaacaatttgtcacttacagacaacttaatatgcacgttagagaacactatatgaaattattctgtgatcaatgtggtgctggtttcattaccgccactgcaatgactaatcatttaaaatcccacgaaacaggttcgtatccttgccctgaatgtggtaaagtctttaaaaacaaaatggggaaagatgaacatgttaaagtagtacacgctagaactaagaagagcgtatgtaatatttgccgcgagagattctttgaatacctcgagaaacttaaacacatgaaggaggttcacaacgcgaagattccgacctataaatgcaatttttgtccaaaggtttatttaaaaagttcagatttaaagaaacatgagaatttgtcgcatctaaaatctacttgctatagatgcgatatatgcaattacagtcaccataacaaggcttcgctgaagaggcacatgattgttcataatggggagaaaatccataaatgtcacgtatgtggcaaggcgtacgctagaaagagcactttgaggcagcatttgaggattcatgccgatgacagacgatttaaatgtaattattgtgataaggccttcgtgcagaaatgtagtttgaaagggcatatgaaaactcaccataaaggtgttaCTTTTGAGTAG
Protein Sequence
MIIFLFLGDRSKIKIKPTRTKTITIKKTPHISEKDLLQNSLLIKKEFLPTGDVSLSNSVDFKDETLVTVKEEHVDSADNEYAATVRSITIKKKKKLMVIPTNRMIMKPLPANTTRKSAITLLRDTTLCPFKFNQGSFQCFYCTDLFLNIKQVEEHVTEHDALTKDDIYKVLVRKSTSDLIKLNVREYGCKICNDTSENLNALKQHLTDKHGLRFNPESDGVALYKIDEDKFECAHCTKQFVTYRQLNMHVREHYMKLFCDQCGAGFITATAMTNHLKSHETGSYPCPECGKVFKNKMGKDEHVKVVHARTKKSVCNICRERFFEYLEKLKHMKEVHNAKIPTYKCNFCPKVYLKSSDLKKHENLSHLKSTCYRCDICNYSHHNKASLKRHMIVHNGEKIHKCHVCGKAYARKSTLRQHLRIHADDRRFKCNYCDKAFVQKCSLKGHMKTHHKGVTFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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