Basic Information

Insect: Ectemnius cavifrons
Gene Symbol: znf423
Assembly: GCA_964023945.1
Location: OZ030383.1:9935840-9947247[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 2.7e-05 0.0024 18.3 1.5 1 23 92 114 92 114 0.98

2 21 0.12 11 6.8 4.3 1 23 120 142 120 142 0.98

3 21 1e-06 9.1e-05 22.8 4.1 1 23 148 170 148 170 0.99

4 21 0.00021 0.019 15.5 0.2 1 23 176 198 176 198 0.99

5 21 0.00018 0.017 15.7 0.5 1 23 359 382 359 382 0.96

6 21 0.4 35 5.2 0.0 2 23 393 415 392 415 0.88

7 21 0.14 13 6.6 0.1 3 23 475 495 474 495 0.97

8 21 0.0047 0.42 11.2 0.6 1 23 507 529 507 529 0.96

9 21 0.0046 0.41 11.3 0.5 1 23 538 561 538 561 0.92

10 21 3.5 3.1e+02 2.2 0.2 1 23 566 589 566 589 0.91

11 21 0.093 8.4 7.2 2.0 2 23 662 683 662 683 0.96

12 21 0.0079 0.71 10.5 0.0 1 23 688 711 688 711 0.94

13 21 3.1 2.8e+02 2.4 0.1 2 23 775 798 774 798 0.81

14 21 5.5e-05 0.0049 17.3 0.9 2 23 815 837 814 837 0.96

15 21 1 93 3.9 0.6 1 12 846 857 846 869 0.76

16 21 0.53 47 4.8 0.2 2 23 877 898 876 898 0.96

17 21 0.0058 0.52 11.0 0.1 2 23 1057 1079 1056 1079 0.93

18 21 0.15 14 6.5 0.3 1 23 1087 1110 1087 1110 0.95

19 21 2.3 2.1e+02 2.8 0.2 2 23 1122 1143 1121 1143 0.93

20 21 0.029 2.6 8.8 0.1 2 23 1152 1174 1151 1174 0.94

21 21 0.022 2 9.1 1.8 1 23 1181 1204 1181 1204 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	2.7e-05	0.0024	18.3	1.5	1	23	92	114	92	114	0.98
2	21	0.12	11	6.8	4.3	1	23	120	142	120	142	0.98
3	21	1e-06	9.1e-05	22.8	4.1	1	23	148	170	148	170	0.99
4	21	0.00021	0.019	15.5	0.2	1	23	176	198	176	198	0.99
5	21	0.00018	0.017	15.7	0.5	1	23	359	382	359	382	0.96
6	21	0.4	35	5.2	0.0	2	23	393	415	392	415	0.88
7	21	0.14	13	6.6	0.1	3	23	475	495	474	495	0.97
8	21	0.0047	0.42	11.2	0.6	1	23	507	529	507	529	0.96
9	21	0.0046	0.41	11.3	0.5	1	23	538	561	538	561	0.92
10	21	3.5	3.1e+02	2.2	0.2	1	23	566	589	566	589	0.91
11	21	0.093	8.4	7.2	2.0	2	23	662	683	662	683	0.96
12	21	0.0079	0.71	10.5	0.0	1	23	688	711	688	711	0.94
13	21	3.1	2.8e+02	2.4	0.1	2	23	775	798	774	798	0.81
14	21	5.5e-05	0.0049	17.3	0.9	2	23	815	837	814	837	0.96
15	21	1	93	3.9	0.6	1	12	846	857	846	869	0.76
16	21	0.53	47	4.8	0.2	2	23	877	898	876	898	0.96
17	21	0.0058	0.52	11.0	0.1	2	23	1057	1079	1056	1079	0.93
18	21	0.15	14	6.5	0.3	1	23	1087	1110	1087	1110	0.95
19	21	2.3	2.1e+02	2.8	0.2	2	23	1122	1143	1121	1143	0.93
20	21	0.029	2.6	8.8	0.1	2	23	1152	1174	1151	1174	0.94
21	21	0.022	2	9.1	1.8	1	23	1181	1204	1181	1204	0.97

Sequence Information

Coding Sequence: ATGCTCTTCAAGGGTAACAGTTCGCGGCTGGAATTGCTGATCGGCAAGATTCAAGCGCACAAGGAACCCTCGCAGGACGAGCGACATAAATCCAAAGAGGCTTTAGGAACCGGAAGTTCCTCATGGCACAGCGAGGATGGCGGGCCGACGTCTCGTCGGGGTGGCGAGACGCCGTCCTCCTGTGCGACGCCGACCTCGGCAAGTTTCCCGTCGGAACCAGAGGCGGACACCGACGTCGGCGTGAACGCCGACGGCAATAGCGCCGCGGCGCCTTATCCCTGCCAATTTTGCGAGCGCACCTTTCCTCGATTGAGCTACCTGAAGAAGCACGAGCAAAGCCACGGCGATCAGATGCCATATCGGTGCAGTTGGTGCGAGAGGCTCTTCAAGCACAAACGAAGTCGTGATCGCCACGTGAAGCTGCACACCGGCGACCGAAGATACCGATGCTCGCATTGCGAGGCGGCATTCTCCAGAAGtgaCCACCTGAAGATCCATATGAAAACCCATGACACCCAGAAGCCGTATCAGTGCACCGCTTGTTCCAGAGGATACAACACCGCAGCTGCCCTAACGTCGCACATGCAATCACACAAGAAGCATCACCAGTCTTCCACTCAAGGCTTGACCAAGTTGCAAGAGGTCGATTACGGTCGCAGAAGTGTATCATCTCACAGTACATCCTCGCCACCAGCAGCCAGTTCACCTTCGCCTTCACTCAACTTGAGTTTGAATCCGAAATTACCGCAGAAATCGTCCCAGGGTAGTTGCAGCGCTTCGACCACACCGATCCTTAATTCACCCTTGAAACTGGCGTGCATGTACTGCACGAGAGATTCGTTCAGCTGCATGCAGCAGCTGCAAATGCATGTGCACACGATGCACCAGGCAATCCTGAGCGGGGAAAGTCTTGGAGCGGGGGTGCCGGCATCGCCGAATAGAGCGGGTGAAACTGTGTCAGGATACCAAAGGGATAAGATTCTTGATCGGTCGGAAAGCTCTTCGAAGGAACACGAGAGGAAATATCAAGAGGAGCAAGAAAAGCATTTAGAGAAGGAGCAATATGACAATGCGTTCACTTGTAATCAGTGTACGATGAAGTTCTCAACCCTAGGTTTGCTCAGGGATCATTTGATATCGATTCATAGAACCGATGGTTTTGGATCTGCCCTGATGATGTGTCCTCTTTGTGGTATACCTTGTGCTTCCGCTGCCGCTTACGCCGAACATTACGTTCTACAACATTGTGAAAATCGAAGGGTTGGCGCCCTTGATTACCCGGAGCATAAGATGAATGGGATGTTCGATTCCTCGAAGAATTCAAGGTTACAGAAGAACAGGGAACAGACGAGCACGGAACCAGCAGACTTAACTAGCAAACATTCCAGAACGAGTGAGAGTTATTCATCCGGTACGCTGCTTTGCGGACAATGTGGAGCTGCTTTGAAAGATTTCGAATCGTTCAGGGTACACTTGGCAAGACACCTTCAAGCTGATCATCGAAACGAAGTAGCTAGGCACCCATGTCCAAAGTGTGAAGCTAGTTTCCAAGATAGGGAAGACATGCTCTCTCACCTGACCAAACATTATCTTGGTCAGATTAGTAAAGAGTACGCTTGCGGTGCCTGCAAGAAGCTCTACTCGCATCCAGATCTTCTTCAGAGACACTTGTTGGACAGCCACGCTCACCACTTGTACAGATGTGCCTTGTGCAGAGACACCTTCGACTCGAGGGTCGCGATACAGGTGCACTTCGCCGTTAAACATAGCCAGGAGTGCAGGATCTATAGATGCAATGCTTGCACACTCTCCAATAATGAGAATTCGCCTGGGAATGCACCTGGCGAAGGACGAACTTTCTTCAGGAGCGAAGCGGAAATGGCGAATCATGTTAGAAGTGTGCATGCACCACCTTCCTTGCCAAGTAGTAGTCCGATTGCTAGAAGTCCAGCTTCCACGCCTGGTATCGCCACTCCTGGACCGAGATGCGTCTTTTGCGGAATATGTTGCAGTTCCGAACTTGAGCTGCAATTACATCTTGCCAGTCATTCGACCAGTCTGTACAGATGTCCCATTTGTAGAGAGGGTTTTGCAGTGGAGTTCTTATTAGACAGGCATCTCGCTCAAGCTCATCAGTCTGCTGAGCACCAGCCGCTCGTTAAGAGCCAATCCAGGGAGAACGGAAGGATACCTAGGCCGCCCAGATACCAAGAAGAAACGAAGTCGCAGAAAAGGGGTCGTTCACCCGCATCGAGTAACAACAACTCCTTGAATCAGAGggataacaataataaaagacCGAACTACGGTGGAGGGGGCCAACAGTGTGAACTCTGCGAGAGGGGTGAATTTGCTAATGAGGCGGAATTGCAAGCCCACAAGAAATTAGTACATGCACCAGCGACGAAGGTGCAAAGTAAATCTCTGTCGAGCCTTAGTATGTCTTGTGCCTATTGTGGCGAGGTCTGTCGATCGAGATCCGACCTCGAATCACATACAAGGATCCAACACGCTTCGAATGAACCTGGTGGTCGACATAAGTGTAATATTTGCGACGAGGTGTGTCCATCGGGGGCGATTCTGGCGGAACACAAGCTGCAAAAACATTGTAAGATCCAGTTGAGCGATACTTGTGTAGTCTGTCGTGGTAGCTTGTCTTCCGAGAGCCAGTTCCTCGAACACGTACAGAGACACAGTCTGGAAAGCGTCGATCCTCAGCAAAGACTAGACGCATCTTTGCCGCATCTTCCAGCACCGTGTGTCGTCTGCAGGCAGACGTTAATCAGCGACTTAGAGTGTCGTCTTCATGCTCGACATCATCTTAGAGCTTCAACGGGTTCCCAGAGTTCGACTTCCAGTCCCAGTCCGAAAAGTCAAAATCCAGGTTGTTGCCTCTGTCTGAGGGAATTCTCGGCGGATGATTTCGTCAGTTTGCCTCCGAGCCACATAACCGGCACTGGCCAATCCCTGAGAGTTTGTAAACCATGCTATATCCGTCACTCTCAGGGTCTCCCCATCCTGAATTCCCCCTACGAGCACGTGAGTCCAGCAAAATGGATGTCCGGTAAGGAGTTACAATGGGATTCGCCTAAAGATAGATGGGAATCAAAAAAGAACTTCAAGCCTGATGAAAGATCAGAAGCTGGCACTACGAATAACGATAGCAAGCGATGTGATGACTGTGGGGTGAAATTCGAAGACCCAGAAGAAGCAGAGAAGCATAGACTGGCGGAACATGACAAGAATGGGGCAAACACTTATACTTGCATACAATGCCAGATGTCATTCCCAACGGAAGCAAAAATTCAACAGCACGTACGGCAAGAACATTTAGAGACGTTGGGAAAAACCGCGGAGTCCTTGCAATGTCACCTTTGCCTCTTCGAAGCAGCCAGTCCTCTGCAGTTGCAAAGTCACCTGATAGAACATACATTCGCAGGCTGTGCTGCTTTAAGCTGTTACATTTGTCAATCTGTGTTCACGGCACCCATCGGCCTTcaaAATCACATGCTGCAAGAGCATGGTCTGAGCGCACGACCCTATGACTGTTCACGCTGTCCACTCAAATTCTTCTTCCGCGCCGAATTGGATCATCATATTTTGACCTATCATCGTCTCAGGGATGATCCCCAGTTAATTGATGTCCAATCGAAAGTTGTACAAAGAAACGAGGATGCTGAGGAATCTGTAACAGTCAAGGAAGAGGTCTCAGGCGCTCTTcatgaagaggaagaggaagaagaagtcaATGTTGACGGACATATAGACCAGGAAGATCATGTGGAAAGTGCGAGTAATGATTTAAAATCCAGATCCAAAATATGCGAGCGAGAAGAACCTGGCGACAACACAGACTCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPSQDERHKSKEALGTGSSSWHSEDGGPTSRRGGETPSSCATPTSASFPSEPEADTDVGVNADGNSAAAPYPCQFCERTFPRLSYLKKHEQSHGDQMPYRCSWCERLFKHKRSRDRHVKLHTGDRRYRCSHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSSTQGLTKLQEVDYGRRSVSSHSTSSPPAASSPSPSLNLSLNPKLPQKSSQGSCSASTTPILNSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGESLGAGVPASPNRAGETVSGYQRDKILDRSESSSKEHERKYQEEQEKHLEKEQYDNAFTCNQCTMKFSTLGLLRDHLISIHRTDGFGSALMMCPLCGIPCASAAAYAEHYVLQHCENRRVGALDYPEHKMNGMFDSSKNSRLQKNREQTSTEPADLTSKHSRTSESYSSGTLLCGQCGAALKDFESFRVHLARHLQADHRNEVARHPCPKCEASFQDREDMLSHLTKHYLGQISKEYACGACKKLYSHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTLSNNENSPGNAPGEGRTFFRSEAEMANHVRSVHAPPSLPSSSPIARSPASTPGIATPGPRCVFCGICCSSELELQLHLASHSTSLYRCPICREGFAVEFLLDRHLAQAHQSAEHQPLVKSQSRENGRIPRPPRYQEETKSQKRGRSPASSNNNSLNQRDNNNKRPNYGGGGQQCELCERGEFANEAELQAHKKLVHAPATKVQSKSLSSLSMSCAYCGEVCRSRSDLESHTRIQHASNEPGGRHKCNICDEVCPSGAILAEHKLQKHCKIQLSDTCVVCRGSLSSESQFLEHVQRHSLESVDPQQRLDASLPHLPAPCVVCRQTLISDLECRLHARHHLRASTGSQSSTSSPSPKSQNPGCCLCLREFSADDFVSLPPSHITGTGQSLRVCKPCYIRHSQGLPILNSPYEHVSPAKWMSGKELQWDSPKDRWESKKNFKPDERSEAGTTNNDSKRCDDCGVKFEDPEEAEKHRLAEHDKNGANTYTCIQCQMSFPTEAKIQQHVRQEHLETLGKTAESLQCHLCLFEAASPLQLQSHLIEHTFAGCAALSCYICQSVFTAPIGLQNHMLQEHGLSARPYDCSRCPLKFFFRAELDHHILTYHRLRDDPQLIDVQSKVVQRNEDAEESVTVKEEVSGALHEEEEEEEVNVDGHIDQEDHVESASNDLKSRSKICEREEPGDNTDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00391507;
90% Identity: iTF_00391507;
80% Identity: -