Basic Information

Gene Symbol
-
Assembly
GCA_932527285.1
Location
CAKOBM010000038.1:443736-446911[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.16 9.3 7.2 0.9 2 23 34 56 33 56 0.91
2 17 3.9 2.3e+02 2.8 1.6 2 23 81 102 80 103 0.94
3 17 0.0016 0.097 13.4 1.3 2 23 126 147 125 147 0.97
4 17 2.4e-06 0.00014 22.4 0.2 1 23 151 174 151 174 0.97
5 17 1.8 1.1e+02 3.8 1.0 3 21 181 199 179 200 0.91
6 17 0.097 5.8 7.8 0.2 1 23 207 230 207 230 0.94
7 17 0.0041 0.25 12.2 0.1 2 20 238 256 238 258 0.92
8 17 0.81 48 5.0 1.1 2 23 298 320 297 320 0.91
9 17 0.0068 0.4 11.5 1.1 2 23 345 366 344 367 0.95
10 17 0.22 13 6.8 1.3 2 23 390 411 389 411 0.95
11 17 2.1e-05 0.0013 19.4 0.3 1 23 415 438 415 438 0.97
12 17 4.1 2.4e+02 2.8 0.3 1 20 443 462 443 464 0.86
13 17 0.017 1 10.2 2.9 1 23 471 494 471 494 0.96
14 17 0.0089 0.53 11.1 0.9 1 23 501 524 501 524 0.94
15 17 9.1e-05 0.0054 17.4 1.5 2 23 530 551 529 551 0.97
16 17 1.8e-05 0.0011 19.6 0.7 1 20 557 576 557 579 0.93
17 17 2.1e-05 0.0012 19.4 6.5 1 23 585 608 585 608 0.98

Sequence Information

Coding Sequence
ATGAACGGGAATTACAATGCGCCTGCAGCGAGACACAACGCTGGACTAATCGTGAAACATTCGACAGTGTACCCGTTCAGACTCCCCGTAAACTGTATGGTCTGTGTATTCTGCTGTGAAAGTTTCGAAGAACCCTCGTCATTTAGAAAGCATATGGATTTGGAACACAAAACGTTCACACTTAAATATATGTTTGAACATTGTCGTGAAAGCTTTTTAAAAGCTGATTGCTCTGATGTCAAATGCCGCATATGCTTACAACCATGCCAATCTTTAGAAGAAATCGCAATTCATTTAAAAAAGCATCACCAGAAACCGTTAGACTTGGAAGTTCCTTTGGGGATAGAACCTTTCAATTTCAAATCCGATAAAATGTCTTGCGCGATTTGCAAAAGAAAAGCCTATAACTTGCGTCAGCTCAGTCGGCACATGAAGACGCATTTCCATAGGTTTACGTGTGACTCCTGCGGAAAATCATATGCTACCAATGGATCGCTACAAGTCCATATTAAAATATCGCACATGATAAAAGGACATTTATGCAGAAAATGCAAAACTCAATTTGATTCGTTAGATGCTAAAAGAGATCATATACAAAACTCACCAAAATGTATGTTATACACGTGCAACCTCTGTGGGGAAAGATTAATGTCAGTCGTATCTAAACGGCAGCACATGAACGAAGTCCACGGGATCGCAAAGAAACCGCGCGTCTGTCCTGAATGTGGGCAAATATTCAAAAGCGAAAATTCTTTTGTAAACCATTTTAAAGCGTTTCTTTTTGTTCTAGAAATGAAATGGAATAAAAATGCGTCTGCGGCGAGACGCAACGCCGGACTTATCATGGAATATACAACAGTGTATCCGTTCAGACTTCCTTTAAATTGTATAGTTTGCGTGTTCTGCTGTAAAAGTTTCGAAGAATCATCCGTATTTAGAAACCACATGGATTTGGAACATACGACGTTCACACTGCAAGATGCACTGAGGCATTGTCCTGTAGATTTTATAAAAGCTGATTGTTCTGATGTGAAATGCCGCATCTGTTCACAAACATTTCAATCTCTTGAAAACATTGCAGCCCACTTAAAAAATCACCACCAGAAACCGATGGACTTGGACGCACCTTTAGGGATAGAGCCTTTCAATTTGAAATCGAACAAACTTAAATGTGCGATTTGCATGAGGAAAGCTTATAATCTGCGACAGCTCAGTCGACATACGAAGACTCATTTTCATAGATTTTCATGCGATTCCTGCGGAAAATCATATGCTACCAATGCATCATTGAAACTTCACGTGAAAATAACTCACATCATTAAAGGTTATCTATGCTCTAGATGCAAAACTCAATTTGATTCGTTAGAAGCAAAAAAGGATCATGTGCTAAATTCACCAAGATGCCGATTATACACTTGCAACATGTGCGACGAAAGATTCATATCCGATGTTAAGAAACAGCAGCACATGAATAATTGTCACGGGATCGCAAAGGAATCGCATGTTTGTCCTGAATGTGGTCAGCTGTTTCAAAGTAAGAGGGCTTTTGCGGTCCACTTTAAACTGACTCACACGAACGACTATGTGCCTTGCCCCCATTGCGGACTTAAATTTTATACGAGATTTTTATACGAAAAACACAGATTAACTCATACAAACGAAAAACCACATTCTTGCACAATTTGTGATAAGGCTTATACTACTAAATCTGGTCTAAACATGCATATGTGGGTACATAAAGAGGAAAAAAGGTTCGAATGTAACCATTGTCATAAAAAGTTTAATCAGAAAGTCAGTTTGCTATCCCACATAAAAACAAAACATCTCTGCTTAGTTTCGATCTAA
Protein Sequence
MNGNYNAPAARHNAGLIVKHSTVYPFRLPVNCMVCVFCCESFEEPSSFRKHMDLEHKTFTLKYMFEHCRESFLKADCSDVKCRICLQPCQSLEEIAIHLKKHHQKPLDLEVPLGIEPFNFKSDKMSCAICKRKAYNLRQLSRHMKTHFHRFTCDSCGKSYATNGSLQVHIKISHMIKGHLCRKCKTQFDSLDAKRDHIQNSPKCMLYTCNLCGERLMSVVSKRQHMNEVHGIAKKPRVCPECGQIFKSENSFVNHFKAFLFVLEMKWNKNASAARRNAGLIMEYTTVYPFRLPLNCIVCVFCCKSFEESSVFRNHMDLEHTTFTLQDALRHCPVDFIKADCSDVKCRICSQTFQSLENIAAHLKNHHQKPMDLDAPLGIEPFNLKSNKLKCAICMRKAYNLRQLSRHTKTHFHRFSCDSCGKSYATNASLKLHVKITHIIKGYLCSRCKTQFDSLEAKKDHVLNSPRCRLYTCNMCDERFISDVKKQQHMNNCHGIAKESHVCPECGQLFQSKRAFAVHFKLTHTNDYVPCPHCGLKFYTRFLYEKHRLTHTNEKPHSCTICDKAYTTKSGLNMHMWVHKEEKRFECNHCHKKFNQKVSLLSHIKTKHLCLVSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-