Basic Information

Gene Symbol
-
Assembly
GCA_932527285.1
Location
CAKOBM010000038.1:4007243-4009360[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.0013 0.078 13.7 3.0 1 23 135 157 135 157 0.98
2 15 4.6e-05 0.0027 18.3 0.8 1 23 163 186 163 186 0.92
3 15 0.48 28 5.7 2.1 3 23 195 215 194 215 0.96
4 15 0.00073 0.043 14.5 2.6 1 23 223 245 223 245 0.96
5 15 1.5e-05 0.00091 19.8 1.8 1 23 254 276 254 276 0.96
6 15 8.9e-08 5.3e-06 26.9 2.1 1 23 282 304 282 304 0.99
7 15 2.6e-05 0.0015 19.1 3.3 1 23 310 332 310 332 0.98
8 15 2.2e-06 0.00013 22.5 1.3 1 23 338 360 338 360 0.98
9 15 8.1e-05 0.0048 17.5 2.0 1 23 366 388 366 388 0.97
10 15 1.2e-06 7.4e-05 23.2 0.2 1 23 394 416 394 416 0.98
11 15 1.7e-06 0.0001 22.8 5.6 1 23 422 444 422 444 0.97
12 15 1.2e-07 7e-06 26.5 0.4 1 23 450 472 450 472 0.98
13 15 6.1e-06 0.00036 21.1 0.6 1 23 478 500 478 500 0.98
14 15 7.7e-07 4.5e-05 23.9 0.6 1 23 506 529 506 529 0.97
15 15 2.6e-05 0.0015 19.1 1.1 1 23 535 557 535 557 0.96

Sequence Information

Coding Sequence
ATGACTCAAACAGCAGAGACTGCTCTAACACAAATGTTTGAAAATGGATCTAAGCTCACAGAAGACATACCCAGTATGCTGTTTGTGAAACCTCACAATTTATCAATGACAGTTGTGATGCACACATCATTTGATGATCTCGAAGAGGCTGTGAAAGAGGAGCTGTCAGAATCTACTGATTATTTCGGTGATTTTGATGATGGTGATAAATGTGTCAAGGATGAAGCTAGAATCACATTTGACCCAAAAACTGTAATCAGAATTGACCTCAAGGATATTAAATCAGAAAACACTGAAACTTGCCCTAAAAATGAAGAAAGCTTATTCCAGAACCCCAATAATTTAAGCTCTGATAAAATTTATAACACTAAAGAGATTCCAGATGAGACTACTGATTTATGCTACTTTTGTCCGACATGCAACAAAAAACACGTCACAAAAAAGGCGTTGAGTCAGCACAtgagagtacacgatccaagtcgaacttatgcatgcgatatttgcgaatataggtttaataccaaagctaacttaaaaactcacaaggacaacttacatcgaaccgaaagcgaaacagtagcatgcacagtttgtcataaacttatgaacagtcaacaaatcttaaaacgacacatgaaaatacattcagaaaagccgccgaaaattcacgcttgcgatagatgcgagcttaaattttccgacaggagtaccttagttagacacaagactacgcacaccgaaggcacgccaggaaaaccacacgcttgtcaaatatgcgacaagacattctcagttatatactacttaaaaagtcatatgaaactacacagcggagatagaccgtactcgtgcgaacgatgcggcaaggcgttcacattgaacagccatctgacaatacacatgagaacgcacaccggtgaaaagccatacgcttgtaacaaatgcgacaagagatactcctctctcgctcacgtcaagtaccacatgaaaacgcacaccggagagaaggacttcgtctgcgatgtatgccagaaagcattctcagaaagcagccactggaagagtcatatgaaaatacacacgggtgtgaaggacttcgcgtgcgacatgtgcgataagaaattcatcggtcacaccaacctgaaactgcataagcggatacacacgggcgttaagccgcacgtctgcgatgtttgcgggaaagcgttcgcgcagaagtctgtattgataatacacgtacgaacacatacgggggagaaaccgttcgcgtgtcaccgatgtgggaaaacattcaccatgtccacgcatctacgaactcatatgcgtatacacacgggcgaaaagcctttcgcatgcgagatctgtgggaaaacgttcgctgaaaacgctcgtttgaaacgacacatgagaacgcacacgggcgagagaccgtacccatgtacaatgtgcgacaaatccttcgccgactacacaaacatgaagactcacctcgtcacccatactgggcaaaagccatacgcgtgcgatagatgcggtaagaccttcacgcagcaaggcactatgaagaagcatataaaaatagttcatctgaaagagagaccgcatgcgtgtaacatgtgccctaagacgtacgccaaacgacaggctttgaaagttcacgtgcgaacacataccggtgaaaGCGATAAAGTTAAATAA
Protein Sequence
MTQTAETALTQMFENGSKLTEDIPSMLFVKPHNLSMTVVMHTSFDDLEEAVKEELSESTDYFGDFDDGDKCVKDEARITFDPKTVIRIDLKDIKSENTETCPKNEESLFQNPNNLSSDKIYNTKEIPDETTDLCYFCPTCNKKHVTKKALSQHMRVHDPSRTYACDICEYRFNTKANLKTHKDNLHRTESETVACTVCHKLMNSQQILKRHMKIHSEKPPKIHACDRCELKFSDRSTLVRHKTTHTEGTPGKPHACQICDKTFSVIYYLKSHMKLHSGDRPYSCERCGKAFTLNSHLTIHMRTHTGEKPYACNKCDKRYSSLAHVKYHMKTHTGEKDFVCDVCQKAFSESSHWKSHMKIHTGVKDFACDMCDKKFIGHTNLKLHKRIHTGVKPHVCDVCGKAFAQKSVLIIHVRTHTGEKPFACHRCGKTFTMSTHLRTHMRIHTGEKPFACEICGKTFAENARLKRHMRTHTGERPYPCTMCDKSFADYTNMKTHLVTHTGQKPYACDRCGKTFTQQGTMKKHIKIVHLKERPHACNMCPKTYAKRQALKVHVRTHTGESDKVK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00737672;
90% Identity
-
80% Identity
-