Esim021983.1
Basic Information
- Insect
- Ecitophya simulans
- Gene Symbol
- ZFHX3_2
- Assembly
- GCA_027574965.2
- Location
- JAODGE020032513.1:3965783-3972461[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.0019 0.26 12.2 1.6 1 23 25 47 25 47 0.97 2 9 0.00041 0.057 14.2 0.7 2 23 54 76 53 76 0.94 3 9 0.00052 0.073 13.9 3.2 1 23 184 208 184 208 0.92 4 9 0.0032 0.45 11.4 0.6 1 22 228 249 228 252 0.89 5 9 0.00064 0.089 13.6 0.2 1 23 304 328 304 328 0.93 6 9 0.0011 0.15 12.9 0.1 2 21 401 420 401 421 0.95 7 9 6.9e-05 0.0095 16.7 2.5 1 23 1095 1117 1095 1117 0.99 8 9 0.0038 0.52 11.2 0.4 2 23 1305 1327 1304 1327 0.96 9 9 0.59 82 4.3 3.2 3 23 1596 1618 1594 1618 0.89
Sequence Information
- Coding Sequence
- ATGCACTTCAAAGACGTGCACGCCAAGAACTCGGTGACGCAGATGAGTGTGTCCGAAAAGCACGTGTACAAATATCGATGCAATCAATGTTCCTTAGCGTTCAAAACCTTGGAGAAACTGCAGCTTCATTCGCAGTATCATCTCATTCGCGACGCGACCAAGTGCGTGCTGTGCGGCCGCAGCTTCCGGTCGTTGGTCGCGCTGCACAAGCACGTCGAAAGCGTGCATTCGGAGCTCACCGACGAAGAGCTCAACGCATACAAGCAGAGCCTCATGAACAACCCCCTATTGTTGGCCGGCCTGCAAGGTCAGGTCCTTGACAGTTCCACAAACGACATCCTGAAAAAGGAATCGCTCCGTGCCGACGACGTAGAATCAGTTGCGGATGGTGATGATAGCAAAGAATTGTCCACCAGCCACGACGACAGCAACGCCAACGACGGCGAGAACTCCAACGACAGCATAATTTACAAAGATCAGCAATTCTTGGAAGATTACCTGAACAGTCAGGCGATCGCCGAGGACAGCTACAACGATCCAAACAGAAAGTACAAGTGCCACCGCTGTAAGGTAGCGTTTACGCGACAGAACTATCTCACCGCCCACAACAAAACCCTTCTGCATCGCAAGGGCGAGAAGCTGAGCTACCCCATGGAGAAGTACCTTGACCCGAATCGGCCGTACAAATGCGACGTCTGTAAAGAGAGTTTCACGCAGAAGAACATCTTGCTGGTCCACTACAATTCCGTAAGTCATTTGCACAAGCTTAAGCGTGCCATGCAAGAGCAgcagcaaaacaacaacaacaacaatccgCCGGTATCGCCGGTCACCGGAGGCCAATCAGCGGTGCAAGCTCCTGGCACGCCGAAGAGCACGTCGAGTAACGAAGACGACGATAAGAAACGCTATCgctgcaatatttgcaaagtgGCGTACACGCAGGGTTCTACGCTCGACATCCACATGCGCTCGGTGCTCCAtcagacgcgcgcgtccaagTTACAAGACCTCGCCATGGCCGGTCAAATCGACCTTTCTAAGCCTCTTATCGAGCAGCCCGATGCGGCCGCCGTACAGTCTCCGAAACATGCAAGCCCAACGTCGGGCGGAGGGGAGAAGACATCCCCCACCCCtccggccgcgtcgcccgTGCCCTCGGCAGGTAGCGCATCGGCAGGTAGCCAGGGGATGATGCCGACGTGCCCGAAGTGCGGTGCGCTCTTCAGTTCGTCGGACCAGTTGAGCGTACACCAGCAACTGTACTGCatgttcgccgcgccgaacatGGCGATATTCCAAGCGCACGAACCCGGTACGGCCAAgagcccgccgcccgccactgccgccggcGAACAGCCGCAACCAAACGACGCCGCAAACAGACTGAGCTTACCAAAGAGAATCAACTCGCAAATGCAGAAACATTTGCTCGAGAGCTACGGCTTCGACGTGGTGATGCACTACAACGAGAGCCAACACCGCAGACGCCAGCAACACGCGGCCGACGAGAGCAAGcggtcgacgacggcgtcgccgccggccgccgccgccgacgattcCGAAGCCACTTCTCGGCCAGCTGAGGACGACACTGAAAACAACTTACCCGAATTCAAGAATGAATACGAAAAGAAAACGGTGGTGGTGAcagcggcgacgtcgtcgacgctgaaTTGCAACCCGCGAGTttcctcgtcgccgaacgcggcggtgggcggcggcaatggcggcggcgagccgacCGACAAAGACGATGAATCGAAAGAGGCGCTACACGCGAAGTTGAACCTGCACACGCCGCCCGAGGCGcactcgacggcgccgtcgacgccgacgtcgtcttcaacgacgccggcgagcagcacgGATTCGCTGCCGGCCAATATTCAAGCGATGATCGCACAGACGATGGCCCAAAACCCGATGGCTTTCGCGCAGCAGGTCAGTGAGATGCAGGCGGCGCTCAACGTGATGCAGCTGCAACAGCAGCTCAACTTCAACCCGATGATGCAGATGATGGGCATGGGCCTGCCACTGGGCCtcaacgcgctcgccgcgatgaATCTTCAGCCGCCGCTCGTGCCGCTGatgatgccgccgccgccgtttgaCGCCATGCAACAGTTCGCGCCGCAGGAGCAGCAGGCCATGATGGCCAAGCAGCAACAGGCGGCCATGATGCAGCAACAAGCGGCTGTTAGCGCGGCCGCGAACCAGaagcgcgctcgcacgcgaaTCACCGACGATCAGTTGAAAATCTTGCGCGCACACTTCGACATTAACAATTCTCCCTCGGAGGAGCAGATCCACGAAATGGCATCTCAATCCGGCCTACCACCGAAAGTCATCAAACATTGGTTCAGGAACACTCTATTCAAAGAACGCCAGAGAAACAAAGACAGTCCGTATAATTTCAACAACCCGCCATCGACTACGTTAAATCTGGAGGAGTATGAAAAGACCGGCGAGGCGAAGGTGATGCCTCTCAACAGCTCAGGGAGCAGCGCCGAAGAGAATAAAAGCAAGGAAtcttcaccgccgccgccctttcAAGCGGCTGAAATTAAGACCGAATTAAAAGAGGAGCCCATGGATGAGACAAACAACGAAAAACATAACGAAACCGACGAGAAACCCAACATTTTCAACTTGCCGCCACATCTTCAGCCGCCCCAGAGTCCGGCTTCATCGATGAGCAGCACCGACAACAATCAACACACCtccacgtcggcgccgtcgacgccgaataATTTAACACTTACATCGATCATTGCATCACAGCTGGGCGATAGCATTATCACGACGAACACACCGTCGCAGATGAACATGACCGCGTCCCCAATGCTGCCACCTCCAAAATTGAACCAACAAAACTACCAGACTCCCAACTCGGCTCTTCAAGGAATGATGCCACTTACACCCAACAGATGTCTCAGTCCGAACCGCGACTTTGCCAATATGAATTCCAACAGCAATAGCTCCACGGGTAGCAGTGGAAAGAGGGCCAATCGCACCAGATTTACTGACTATCAAATTAAAGTGCTGCAAGAGTTCTTCGAGAACAACGCGTATCCGAAAGATGATGACCTCGAATATTTGTCGAAACTGCTGAGCCTCAGTCCTCGTGTGATTGTCGTGTGGTTTCAGAACGCGCGTCAAAAAGCGCGTAAAGTGTATGAAAATCAACCAGCTAGCGAACCCAGTCCTGGTCCAGCTGAACAAACTCCAGCTGCGACAGAAGGTGGTGCCAATCGCTTTCAACGCACGCCCGGTCTCAATTACCAATGCAAGAAATGTCTTTTGGTATTCCAACGTTACTACGAGCTAATCAGGCATCAGAAGACGCATTGTTTCAAAGAAGAAGATGCCAAGAGATCCGCACAGGCgcaggcggccgccgctcAAATTGCAGCCGTTTTAAGCTCTGAGGATTCAAATTCGAGCACTACCATTGAGCAGAATAACACCCAACAACCACAAACACCGGGAAACCAGTCTCAAGATTCTCCATTTGGCATTCTTCAACAACACGCTCAGCTCCAACAGTTGCAACAAGGAGTTTCCGATCTTTCCACACTCGGCGACAAATCGGCATCACCGATTCCACTTCCTCTCATTAACATGTTGAACAATGTCACTACACAAAAGCGCAAACTCGAGGAATACGATGGAGAAAGCGACGTGTCCGATCAACCGAAAGACAAACGTTTGAGGACCACGATCTTACCCGAACAGCTGGACTACTTGTATCAAAAGTACCAGATTGAGAGCAATCCATCGCGCAAAATGTTGGAGAACATCGCGCGCGAGGTAGGTTTGAAGAAACGTGTTGTCCAAGTGTGGTTTcaaaacacgcgcgcacgcgaacgcaaagGGCAGTTTCGAGCGCATGCTCAAGTGATCAATAAGCGTTGCCCTTTCTGCCCGGCATTGTTCAAAGTCAAGTCCGCGTTGGAATCTCATCTTACCACGAAGCATGCCGATCAGTGTGCCCGTGGAGAAATCAACATCGATGCGTTGCCAGACGAGGAAGCTAGTCTCGAATCGTCACCCAGCTTAAGCTCCGGCGGTGACAACAAGTTCGGTGGTTTGGCAGCTAACATGATGCCGCCGCTTTTTCCCAACTTGCACCCGGACATGGAAAATTCAATCAAGAAGTACTACGAGGAGAGTATGAAGAGATACATCAGTGAGCTGCAGGCCCACGCTTCAAATGGCGACAAGAGTGAAATCAAGGGCGAAGAAAAGGAAGAAGGCGGAGAGATTCCTTTGGACCTATCAAAACCAGTCGATTTGTCCCACCCGATGAAGGTAAACATGGACCACGAACGCAATTTGTGCGATCCCGGACCGTTGACCGATTTGAGCGAACGATCGCTGTGTGACGAGCGCATGTCGGATTCTATGTCAGAAACTACCGATTTCATGTACGACGAGAGCAATCCAACTTCGCCCGCTTCTAGCACTCAAAGCAACAACACTCCCGCCAGGCCGCAAAATGCGACGAGCACGCCAAACGCGAATTCCAACTCGAATAAACGCTTTCGCACGCAGATGACCGCTGTGCAAGTTAAAGTCATGAAAACCCTCTTCACCGACTACAAGACACCCACAATGGCCGAATGCGAAATGTTGAGCAGAGAAATTGGACTTCCAAAGCGAGTGGTGCAAGTGTGGTTCCAGAATGCACGTGCCAAGGAGAAGAAGAGCAAGATTGCGTTGCAGAAGGTCCTGGGCAACACAGATGCGGCCGAGAACACAACGCCCACTCTTCCGGACGATTGCAAGTTCTGCAGCTTCAAGTACTCTCACAAGTACTCCATCCAAGATCACATCTTCACCAAGAGCCACATCAGCAACGTGCGAACGCACCTCGAAAACGCCAGCAAGGACAACGCGAATGCCGAAAGCGGAGAATTCCAGGTTCCGCCTATTCCCGGCGCCTCCGTGTCGGCGGATTCTACCACCCATCCGGCCGGAGCTCAGCCAACATTGAACAACAACACCCATCTGCAACTGCTGCAGATGGCCGGCATGCAAATGGCCGCGGCCGCTGTCAAAGGGGaaaacaacgacgacaacaatCAGGAGGCCCTCTTCCAGCAGCTCTACGCCTTGGGCAATAGCGGCAACTTCGGCGGCCAGAATCAGTTCCTGCATCATCCGATGTTTGGCACAAATGGTGAGTCCCAAATTTGA
- Protein Sequence
- MHFKDVHAKNSVTQMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHLIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELNAYKQSLMNNPLLLAGLQGQVLDSSTNDILKKESLRADDVESVADGDDSKELSTSHDDSNANDGENSNDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQNYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQQNNNNNNPPVSPVTGGQSAVQAPGTPKSTSSNEDDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMAGQIDLSKPLIEQPDAAAVQSPKHASPTSGGGEKTSPTPPAASPVPSAGSASAGSQGMMPTCPKCGALFSSSDQLSVHQQLYCMFAAPNMAIFQAHEPGTAKSPPPATAAGEQPQPNDAANRLSLPKRINSQMQKHLLESYGFDVVMHYNESQHRRRQQHAADESKRSTTASPPAAAADDSEATSRPAEDDTENNLPEFKNEYEKKTVVVTAATSSTLNCNPRVSSSPNAAVGGGNGGGEPTDKDDESKEALHAKLNLHTPPEAHSTAPSTPTSSSTTPASSTDSLPANIQAMIAQTMAQNPMAFAQQVSEMQAALNVMQLQQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPFDAMQQFAPQEQQAMMAKQQQAAMMQQQAAVSAAANQKRARTRITDDQLKILRAHFDINNSPSEEQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMPLNSSGSSAEENKSKESSPPPPFQAAEIKTELKEEPMDETNNEKHNETDEKPNIFNLPPHLQPPQSPASSMSSTDNNQHTSTSAPSTPNNLTLTSIIASQLGDSIITTNTPSQMNMTASPMLPPPKLNQQNYQTPNSALQGMMPLTPNRCLSPNRDFANMNSNSNSSTGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPASEPSPGPAEQTPAATEGGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTIEQNNTQQPQTPGNQSQDSPFGILQQHAQLQQLQQGVSDLSTLGDKSASPIPLPLINMLNNVTTQKRKLEEYDGESDVSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCARGEINIDALPDEEASLESSPSLSSGGDNKFGGLAANMMPPLFPNLHPDMENSIKKYYEESMKRYISELQAHASNGDKSEIKGEEKEEGGEIPLDLSKPVDLSHPMKVNMDHERNLCDPGPLTDLSERSLCDERMSDSMSETTDFMYDESNPTSPASSTQSNNTPARPQNATSTPNANSNSNKRFRTQMTAVQVKVMKTLFTDYKTPTMAECEMLSREIGLPKRVVQVWFQNARAKEKKSKIALQKVLGNTDAAENTTPTLPDDCKFCSFKYSHKYSIQDHIFTKSHISNVRTHLENASKDNANAESGEFQVPPIPGASVSADSTTHPAGAQPTLNNNTHLQLLQMAGMQMAAAAVKGENNDDNNQEALFQQLYALGNSGNFGGQNQFLHHPMFGTNGESQI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00631963;
- 90% Identity
- iTF_00631963;
- 80% Identity
- iTF_00631963;