Esim020350.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ecitophya simulans
Gene Symbol
ZNF131
Assembly
GCA_027574965.2
Location
JAODGE020030455.1:1-4607[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.00018 0.025 15.4 0.2 1 23 167 189 167 189 0.97
2 22 0.014 2 9.4 1.8 1 23 195 217 195 217 0.96
3 22 2.3e-05 0.0032 18.2 3.1 1 23 223 245 223 245 0.98
4 22 0.00019 0.026 15.3 1.4 3 23 259 279 257 279 0.95
5 22 0.00039 0.053 14.3 2.3 1 23 285 307 285 307 0.98
6 22 3.8e-06 0.00052 20.7 2.0 1 23 313 335 313 335 0.98
7 22 3.8e-07 5.3e-05 23.8 0.2 1 23 341 363 341 363 0.99
8 22 2.7e-06 0.00037 21.1 0.3 1 23 369 391 369 391 0.99
9 22 0.0009 0.13 13.2 1.2 1 23 397 416 397 416 0.85
10 22 0.00024 0.033 15.0 0.0 2 23 423 445 422 445 0.95
11 22 0.001 0.14 13.0 0.2 1 23 689 711 689 711 0.97
12 22 0.001 0.14 13.0 1.7 1 23 718 740 718 740 0.97
13 22 5.9e-06 0.00081 20.1 3.1 1 23 746 768 746 768 0.98
14 22 0.027 3.7 8.5 1.0 1 21 774 794 774 795 0.94
15 22 0.00023 0.032 15.0 0.8 1 23 820 842 820 842 0.97
16 22 0.00082 0.11 13.3 1.0 1 21 850 870 850 872 0.95
17 22 2.1e-05 0.003 18.3 3.9 1 23 878 900 878 900 0.98
18 22 2.2e-05 0.0031 18.2 0.1 1 23 914 936 914 936 0.98
19 22 2.2e-05 0.0031 18.2 0.5 1 23 957 979 957 979 0.97
20 22 1.6e-06 0.00023 21.8 0.1 2 23 987 1008 986 1008 0.97
21 22 3e-05 0.0041 17.8 1.2 1 23 1013 1035 1013 1035 0.91
22 22 2.6e-05 0.0036 18.0 0.5 2 23 1040 1061 1039 1061 0.97

Sequence Information

Coding Sequence
GTAAAAGAAGGCGACGGCCTACCAGCAAAAATGTGCGTGCAGTGCATTTTGCAATGCAGCCGAGCGTACACCTTCAAGCAAATCTGCGAAAAGTCGGAGACGATCCTGCGCAATTTCATCTCTCCAGAATTCCAAGCGCAACTCTGCGAGGTGCTCGAGCAGAAACAATCCGAAGTAGATGAAGTGGACGTGGACGACGTGACAGAGGAAGACCTCCAAGAGTTTTCCAACACCGTCACAAACGTCGTCATAGAAGATGGACTCCCCGCTCAGATAGTCACGTTCGCCGACGGAACCACAGGATACTATGTGGAGAATGTCACCATAGTCGACGCTGGCATGAACGACCAGGACGACGACACCCTCCAGGAGGAAGACCTTCTTAACGTAGATCTCAAGGAAGAATCGACGTTCTACACCGACGAGGCATACGACAACACTGAGGAAGACCTCTCAGTCGTGGCCGCGACGATCTCCGAAGACAAGGCGGACAAGAGATTCGCATGCACGAAATGCGCGGAAACCTTCGCTCTCAAGGTGGATCTCAAGGTGCACATGATGTCCCATCCCAAGCAATTGGACCATCATTGCGCGGTGTGCAATAAATCCTTCGCCGAGGCGCGCATCCTCAAGCGTCACGCGAAGATCCACCTCGAGAGGAAGCCCCACCAGTGCGACCAGTGCGACATGTCCTTCGCGGAGAGCTCGAACCTCAGCAAGCACAAGAAGAAGCACACCGGCGAGCTGAGAAACATCAAGGGCAAGCCGCACTTGTGTTCGGTGTGCGGCCGCGCGTTCAAGTGGGCGTCGTCCCTGTCCAAGCACATGAAGTACCACACCGGACACAAGCTGCACACCTGCGAATACTGCCGGAAGCAGTACGTCGAGGCGCGGAGTCTGAAAATTCACCTTCGGTCGCACACCGGCGAGCGTCCGCACGTGTGCCCGGTGTGCAGCAAGGCCTTCACGCAGATCTGCAACCTGGAGAAGCACCTCCGAGTGCACACCGGCGAAAAGCCGTACGTGTGCAACGTCTGCGGCAAAGGCTTCACGCAGAGCGGCTACGTGTCGATACACATGCGGACCCACACCGGCGAGCGACCTTACGTGTGCCACACCTGCGGCAAGGCGTTCGCCGGATCGAACACGTTGGCCATTCATCAGCGGATACACACCGGGGAGAAGCCGTACGAGTGCAACATTTGCGGGAAGAGGTTCAGCCGGCTGAAGGTGCATCAGAAGATCCACGCGCTGGACAAGTTAGTGCCCTGCAAAGAATGCGGAATGAGCTACGCCCTCGCCGAACAGCTGCAGGAGCACATGATGAACGCGCACAATTGCATCTTGGACAGCAGTCTGAAGGGTGCCAAGGTCGAAACCGTGGAGATATCCGGTTTGCTTACGGGCGAGACCGTTCATACGGTGCAAGTGCATACCCAGAGCCAAGCAGCGACGGCACGGCGCAGAGCGGCAAACGGCCACGTTCGTGACGTGACGTTCGCGATCCATTCGGAGCTGTGCCCGGCCGAGACGATGGAGAAGAtggacgcgaacgcgctgctGGCGTCGACGCTGCAGCTCGACAAGGTGTGCAGGACGTGCCTcaccgagcgcggcgacatGAAGCCGCTGTTCGGCGCCTGTCTCGACGAAATGCTCGGCGCTATCGCCCAAATCGAGATAAAAGAAAACGATGGCCTCCCGTCGCAGATGTGCATGCAATGCATGCGATTATGCAATCGTGCGTACACGTTCAAAAAGCAGTGCGAAAAGTCCGACTCGATCCTCCGAAACTACGTCGCTTTGAAAACCGAAAACCAGTTGTGCGACGCGCAGGAAATGATATCGGTCGACAACGCGCTGCAGCAGTTTTCCAACGCCGTCACGAACGTCGTCATCGAAGAGCTGCCGCCCGACCTGATTCCGTACGAAAGCAACGGCATTAAGTACTACACGACGACCATCGTCGAACCGCTCAAAACCATCAACGAGGACGGCAACTTCGAGCTGTACATACAGAACGCGGAGCCCGACAGCCCGTCGAAGAAGGAGATCGAGACGCTGTACGCGTGCGCGAAGTGCAACGACACGTTCAAACTGAAGGTCGACCTGGAAGTCCACATGATGTCCCATCCGAAGGACATGGTCCAGCACGTCTGCGGCGTGTGCTACCAGTCGTTCTCGAACGTGCACAGCCTGCAGGACCACGCGAAGGTGCACGTCGCGAAGAAGGCGCACCAGTGCGACAAGTGCGAGATGTCGTTCGACAAGAGCTGGAACCTCACGCGGCACATGAACAAGCACTCGCAGGACCGGCCGTACTTCTGTCCGGTGTGCAAGCGCGCCTTCAAGTGCGCCGCGTACGTCGAGAAGCACATGAAGCAGAACAAGGAGTGCAAACGCTTGCTCGCCGAGCAGAAGACGGTCAAGAAGTCCGCCCCGAAGGCGGTCAACTTTCACCAATGCGACCAGTGCGACATGGCGTTCGCGAAGATCTGGAACCTGAACCGCCACAAGATGCTCCACAAGCAGGACAAGACGCGCCCGTTCATGTGCACGGTGTGCGAGCGCACTTTCGAGTCCTCGGCGGCGCTGTCCGGCCACATGCGATGTCATCCCGACAAGAAGGTGCACACGTGCGACTTTTGCAACAAGCAGTACGTGCAGAAGCGCAGTCTGAAGGTGCACATACGGACGCACACCGGAGAGCGGCCGCCGGTGTTCACCGGCGAGAAGAACTACGTGTGCGAGACGTGCGGGAAGGCGTTCGCTGGGTCGAACTCGTTGGCGCTGCACAAACGCGTCCACGTGCGCAATAATACCGCGGAGGAGACGCAGGAGTTCGTCGAGGAGAGCAACGACAAGAATCATGTTTGTGAGACGTGCGGAAAGGCGTTTTCGGGATCGAATTCTCTCGCGTTGCACAAGCGCGTGCACGTGAAGACGAAGGACGTGTGGGAGTGCGAAGTGTGTAAGAAGAAGTTTGCCCAGCAGGCCGGCTTGGAGGTGCACATGAAGACGCACGAGGAGAGGGCGCACGTTTGCAAGGTTTGCGGGAAGGGATTTGCGTCGTCGAGCCATTTGTCCGGACACATGTGGACGCACAAGAAGGTTGTGCAGTGTGAAATTTGTCTTAAAGAATTCTCGTCGGCGAAGAGCCTCAATAATCACAAACGCATTCATGCGGGGACGGAACTAGAAACGATTGAGACCACCACGACGGTACCCTGTCAGGCATGCGAAGCGCAGTTCCTCACCGAGGAGGAAATGCACGAGCACCTGCTTGACGTGCACCAGCTGAAGGTGGAATCCGTGGAGGCCGTCGGAATTTCGGGATTACTCATCGACCCCACGAGCAACACGATTCGCTTAGCGACGCTGAATTCGTAA
Protein Sequence
VKEGDGLPAKMCVQCILQCSRAYTFKQICEKSETILRNFISPEFQAQLCEVLEQKQSEVDEVDVDDVTEEDLQEFSNTVTNVVIEDGLPAQIVTFADGTTGYYVENVTIVDAGMNDQDDDTLQEEDLLNVDLKEESTFYTDEAYDNTEEDLSVVAATISEDKADKRFACTKCAETFALKVDLKVHMMSHPKQLDHHCAVCNKSFAEARILKRHAKIHLERKPHQCDQCDMSFAESSNLSKHKKKHTGELRNIKGKPHLCSVCGRAFKWASSLSKHMKYHTGHKLHTCEYCRKQYVEARSLKIHLRSHTGERPHVCPVCSKAFTQICNLEKHLRVHTGEKPYVCNVCGKGFTQSGYVSIHMRTHTGERPYVCHTCGKAFAGSNTLAIHQRIHTGEKPYECNICGKRFSRLKVHQKIHALDKLVPCKECGMSYALAEQLQEHMMNAHNCILDSSLKGAKVETVEISGLLTGETVHTVQVHTQSQAATARRRAANGHVRDVTFAIHSELCPAETMEKMDANALLASTLQLDKVCRTCLTERGDMKPLFGACLDEMLGAIAQIEIKENDGLPSQMCMQCMRLCNRAYTFKKQCEKSDSILRNYVALKTENQLCDAQEMISVDNALQQFSNAVTNVVIEELPPDLIPYESNGIKYYTTTIVEPLKTINEDGNFELYIQNAEPDSPSKKEIETLYACAKCNDTFKLKVDLEVHMMSHPKDMVQHVCGVCYQSFSNVHSLQDHAKVHVAKKAHQCDKCEMSFDKSWNLTRHMNKHSQDRPYFCPVCKRAFKCAAYVEKHMKQNKECKRLLAEQKTVKKSAPKAVNFHQCDQCDMAFAKIWNLNRHKMLHKQDKTRPFMCTVCERTFESSAALSGHMRCHPDKKVHTCDFCNKQYVQKRSLKVHIRTHTGERPPVFTGEKNYVCETCGKAFAGSNSLALHKRVHVRNNTAEETQEFVEESNDKNHVCETCGKAFSGSNSLALHKRVHVKTKDVWECEVCKKKFAQQAGLEVHMKTHEERAHVCKVCGKGFASSSHLSGHMWTHKKVVQCEICLKEFSSAKSLNNHKRIHAGTELETIETTTTVPCQACEAQFLTEEEMHEHLLDVHQLKVESVEAVGISGLLIDPTSNTIRLATLNS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-