Basic Information

Insect: Ecitomorpha arachnoides
Gene Symbol: Zfhx3
Assembly: GCA_027574945.2
Location: JAODGD020044524.1:4777079-4786244[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 5.9 9e+02 1.2 1.4 1 23 6 30 6 30 0.90

2 16 1.2 1.9e+02 3.3 0.1 1 21 116 136 116 139 0.78

3 16 0.00012 0.019 15.9 0.2 1 23 150 173 150 173 0.96

4 16 0.22 34 5.7 1.8 2 22 258 278 258 281 0.90

5 16 0.071 11 7.2 0.4 1 23 293 318 293 318 0.89

6 16 0.0024 0.37 11.8 1.6 1 23 336 358 336 358 0.97

7 16 0.00052 0.08 13.9 0.7 2 23 365 387 364 387 0.94

8 16 0.00066 0.1 13.6 3.2 1 23 495 519 495 519 0.92

9 16 0.0041 0.63 11.1 0.6 1 22 539 560 539 563 0.89

10 16 0.00081 0.13 13.3 0.2 1 23 615 639 615 639 0.93

11 16 0.0014 0.21 12.6 0.1 2 21 712 731 712 732 0.95

12 16 0.24 37 5.5 2.5 2 19 854 871 853 876 0.90

13 16 8.7e-05 0.013 16.4 2.5 1 23 1448 1470 1448 1470 0.99

14 16 0.0013 0.19 12.7 0.6 1 23 1560 1582 1560 1582 0.98

15 16 0.0047 0.73 10.9 0.4 2 23 1731 1753 1730 1753 0.96

16 16 2.2 3.3e+02 2.5 2.5 3 23 2022 2044 2020 2044 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	5.9	9e+02	1.2	1.4	1	23	6	30	6	30	0.90
2	16	1.2	1.9e+02	3.3	0.1	1	21	116	136	116	139	0.78
3	16	0.00012	0.019	15.9	0.2	1	23	150	173	150	173	0.96
4	16	0.22	34	5.7	1.8	2	22	258	278	258	281	0.90
5	16	0.071	11	7.2	0.4	1	23	293	318	293	318	0.89
6	16	0.0024	0.37	11.8	1.6	1	23	336	358	336	358	0.97
7	16	0.00052	0.08	13.9	0.7	2	23	365	387	364	387	0.94
8	16	0.00066	0.1	13.6	3.2	1	23	495	519	495	519	0.92
9	16	0.0041	0.63	11.1	0.6	1	22	539	560	539	563	0.89
10	16	0.00081	0.13	13.3	0.2	1	23	615	639	615	639	0.93
11	16	0.0014	0.21	12.6	0.1	2	21	712	731	712	732	0.95
12	16	0.24	37	5.5	2.5	2	19	854	871	853	876	0.90
13	16	8.7e-05	0.013	16.4	2.5	1	23	1448	1470	1448	1470	0.99
14	16	0.0013	0.19	12.7	0.6	1	23	1560	1582	1560	1582	0.98
15	16	0.0047	0.73	10.9	0.4	2	23	1731	1753	1730	1753	0.96
16	16	2.2	3.3e+02	2.5	2.5	3	23	2022	2044	2020	2044	0.89

Sequence Information

Coding Sequence: ATGCCTCCACGCGTGTTCCATTGCTCATTGTGCTCGTTCTCTGCTACCAACCGCCTGCCACTGCTGCAGCACGTCCGATCTCTCAAGCACTTGCATCTCGAGCAACTGCATCAGCTGCAGCGGCGCGCCGAGGGCAAAGAAACCGGCCCCGAAATCGGGGAAGTGTTTCATGTCGTACCTGGACCAGTCGATCAATCCATTTCGGAGCGAAGAGACAGCGTCAATTCGGAGCAGTCAAATCAGGCCGAAAGCAACCATCAGCTCAGCGGCAAGGAGTTCAAGTCGGAGCCGTGCGACGACGAAATGGTCGGCGGCGGCGGCGACGCGGCGAGTGGCGGCGCACAACATGTGTGTCCCTATTGCGACTATGCGAGCGATTCAGAAATGCGCATTCAGGCGCATGTGCTCGCCCAGCACGGTACGAATCACAGTTCCTCGGAGTCAAGCTTTCAATGCCCCCTGTGTCAGGATGCGTTCAAAGATCGCTCCAGCCTCGAGCGGCACGTCATGCAGATTCACTCGGTTAATAGCGAGGGGTTGCAACGGCTGCTGATGCTCGTCGACCAAAGTCACTGGCTCAACCGGTCACCTAACCATCTTAACAACGCCGGCGGTGCGTCCGGCCAGTTGACGTCGCCGACGTCCGTGTCTTCCAAGGACAGCAAACACACGCCCGATAAGGCCTCCACTCCCAATCATGCCGTCGATCTCGAAAACGAACTCATGTCACCGACGCATAGCGACGATGCCGGCGACGTCGCCGAATTCGAGCGTTGCGCTACGTGCATGAAAAGCTTTAAGAACATCGATGAACTGTGTTATCATCAAAACGAAACGGGTCACCTGGAAATCAAACAGACGCCCAGCGGCCCCGGCTACGCGTGTTGGAAGAAGGGCTGCAATCAGTTCTTCCCTACCGCGCAATCGCTTCAGATGCACTTCAAAGACGTGCACGCCAAGAACTCAGTGACGCAGATGAGTGTGTCCGAGAAGCACGTGTACAAATATCGATGCAATCAATGTTCCTTAGCGTTCAAAACTTTGGAGAAACTGCAGCTTCATTCGCAGTATCATCTCATTCGCGACGCGACCAAGTGCGTGCTGTGCGGCCGCAGCTTCCGGTCGTTGGTCGCGCTGCACAAGCACGTTGAAAGCGTGCATTCGGAGCTCACCGACGAAGAGCTCAACGCATACAAGCAGAGTCTCATGACGAACCCTCTATTGTTGGCCGGCCTGCAAGGTCAGGTCCTTGACAGTTCCACCAACGATATCCTGAAAAAGGAATCGCTCCGATCCGACGACGCAGAGTCAGTTGCGGATGGTGATGATAGCAAGGAGTTGTCCACCAGTCACGACGATAGCAACGCCAACGACGGCGAAAATTCCAACGACAGTATAATTTACAAGGATCAGCAATTCTTGGAAGATTACCTGAACAGTCAGGCGATCGCCGAGGACAGCTACAACGATCCAAACAGAAAGTACAAGTGCCACCGTTGCAAGGTAGCGTTTACGCGACAGAACTATCTCACCGCTCACAACAAAACCCTTTTGCACCGCAAGGGTGAGAAGCTTAGCTACCCCATGGAGAAGTACCTTGACCCGAATCGGCCGTACAAATGCGACGTCTGTAAAGAAAGTTTCACGCAGAAGAACATCTTGCTGGTCCACTACAATTCCGTAAGTCATTTGCACAAGCTTAAGCGTGCCATGCAAGAGCAGCAGCAAAACAACAATAACAACAATCCGCCAGTCTCTCCGGTCACCGGAGGCCAATCAGCGGTGCAAGCTCCTGGCACACCCAAGAGCACGTCGAGTAACGAAGACGACGATAAGAAACGCTATCGCTGCAACATTTGCAAAGTGGCGTACACGCAGGGTTCCACGCTCGACATCCACATGCGTTCGGTGCTCCATCAGACGCGCGCCTCCAAGTTACAAGATCTCGCCATGGCCGGTCAAATCGACCTTTCTAAGCCTCTTATCGAGCAGCCCGATGCGGCCGCCGTACAGTCTCCGAAGCATGCGAGTCCAACGCCGGGCGGAGGGGAGAAGACAAGCCCCACCCCTCCGGCCGCGTCGCCCGTGCCCTCGGCAGGTAGCGCACCGGCAGGTAGCCAGGGGATGATGCCGACGTGCCCTAAGTGCGGTGCGCTCTTCAGTTCGTCAGACCAGTTGAGCGTACACCAGCAACTGTACTGCATGTTCGCCGCGCCGAACATGGCCATCTTCCAAGCACACGAACCCGGTACGGCCAAGAGCCCGCCGCCCGCCACAGCCGCCGGCGAACAGCCGCAACCAAACGACGCCGCCAACAGACTGAGCTTACCAAAGAGAATAAATTCGCAAATGCAGAAACATTTGCTCGAGAGCTACGGCTTCGACGTGGTGATGCACTACAACGAGAGCCAGCACCGCAGACGCCATCAGCATGCGGCCGACGAGAGCAAGCGGCCGACGACGGCGTCGCCACCAGCTGCCGCCGCTGACGATTCCGAAGCCACTTCGCGGCCAGCTGAGGACGACACTGAAAACAACTTACCCGAAGTAAGTAAATCCACGTGCCAACATTGCAATAAAGAGTTCTCTAGTGTGTGGGTGTTAAAATCTCACTGTGAAGAAGTACATAAAGATTTAGTGCCGCTAGAATTCTTAGAAAAGTATGCCCAACAGTTCAAGAATGAATACGAAAAGAAAACGGTGGTGGTGACAGCGGCGACGTCGTCGACGTTGAATTGCAACCCGCGAATCTCCTCGTCGCCGAACGCGGCGGTGGGCGGCGGCAATGGCGGCGGCGAGCCGACCGACAAAGACGATGAATCGAAAGAGGCGCTACACGCGAAGTTGAACCTGCACACGCCGCCCGAGGCGCACTCGACGGCACCGTCGACGCCGACGTCGTCTTCAACGACGCCGGCAAGCAGCACGGATTCGCTGCCGGCCAATATTCAAGCGATGATCGCACAGACGATGGCCCAAAACCCGATGGCTTTTGCGCAGCAGGTCAGCGAGATGCAGGCGGCGCTCAACGTGATGCAGCTGCAACAGCAGCTCAACTTCAACCCGATGATGCAGATGATGGGCATGGGCCTGCCTTTGGGCCTCAACGCGCTCGCCGCGATGAATCTTCAGCCGCCGCTTGTGCCGCTGATGATGCCGCCGCCGCCGTTTGACGCCATGCAACAGTTCGCGCCGCAGGAGCAGCAGGCCATGATGGCCAAGCAGCAACAGGCGGCCATGATGCAGCAACAAGCGGCTGTTAGCGCGGCCGCGAACCAGAAGCGCGCACGCACGCGAATCACCGATGATCAGTTGAAAATCTTGCGCGCACACTTCGACATTAACAATTCTCCCTCGGAGGAGCAGATCCACGAAATGGCATCTCAATCCGGCCTACCTCCCAAAGTCATCAAACATTGGTTCAGGAATACGCTATTCAAGGAGCGCCAGAGAAACAAAGACAGTCCGTATAATTTCAACAACCCTCCATCGACTACGTTAAATCTGGAGGAGTATGAAAAGACTGGCGAGGCGAAGGTGATGGTTCTCAACAGCTCTGGGAGCAGCGCCGAAGAGAATAAAAGCAAGGAATCTTCTCCGCCGCCGCCCTTTCAAGCCGCTGAAATTAAGACCGAATTAAAAGAGGAGCCCTTGGATGAGACAAACAACGAAAAACATAACGAAACCGATGAGAAACCCAACATTTTCAACCTGCCGCCACATCTTCAGCCGCCCCAGAGTCCGGCTTCGTCGATGAGCAGCACCGACAACAATCAACACACCTCCACGTCGGCTCCGTCGACACCGAATAATTTAACTCTTACTTCAATCATCGCCTCACAGCTGGGcgataatattatcacGACGAACACACCGTCTCAGATGAACATGACCGCGTCCCCAATGCTGCCACCTCCAAAATTGAACCAGCAAAACTACCAGACCCCCAACTCGACACTTCAAGGAATGATGCCACTTACACCCAATAGATGTCTCAGTCCGAACCGCGACTTTGCCAGCATGAATTCCAACAGCAATAGCTCGACGGGTAGCAGTGGAAAGAGAGCCAATCGCACCAGATTCACTGACTATCAAATTAAAGTGCTGCAAGAGTTCTTCGAGAATAACGCGTATCCTAAAGATGATGATCTCGAATATTTGTCGAAATTGCTGAGTCTCAGCCCACGTGTGATTGTTGTGTGGTTTCAAAACGCGCGTCAAAAAGCGCGTAAAGTGTATGAAAATCAACCAGCCAGCGAACCTAGTCCTGGTCCAGCTGAACAAACTCCAGCGGCGACCGAAGGAGGTGCCAATCGCTTTCAACGCACGCCCGGCCTCAATTACCAATGCAAGAAATGCCTTTTGGTATTCCAACGTTACTACGAGTTAATCAGGCATCAAAAAACGCATTGTTTCAAGGAGGAAGATGCCAAGAGATCTGCTCAAGCGCAGGCAGCTGCTGCTCAAATTGCAGCCGTTTTAAGCTCTGAAGATTCAAATTCGAGCACAACCATTGAGCAGAATAACACCCAACAACCACAAACACCGGGAAACCAGTCTCAAGGGCCGTCTCACAGCCCTGTGCAACCGAATCCGTCAACAACGCCAACTCCTAGTGGACAAAATACACGGCCACCATCTCCATCCGCGTCTCCGGTGGACTCCAAGGAGGGTACCTTCCAATGTGACAAGTGCAATCTAGTTTTTCAACGCTTTGATTTATGGCGTGAACATCAATTGGTTCATATCATGAATCCAACATTATTTCCATCGTACCCACCAGATTCTCCATTTGGCATTCTGCAACAACATGCTCAGCTCCAACAGTTGCAACAAGGAGTTTCCGATCTTTCTACACTCAGCGACAAATCGGCATCACCGATTCCACTTCCGCTCATTAACATGTTGAACAATGTCACTGCACAGAAGCGCAAACTCGAGGAATACGATGGAGAAAGCGACGTATCCGATCAACCAAAAGACAAACGTTTGAGAACCACGATCTTACCTGAACAGCTGGACTACTTGTATCAAAAGTACCAAATTGAAAGCAATCCGTCGCGTAAAATGTTGGAGAACATCGCGCGCGAGGTAGGATTGAAGAAACGTGTTGTCCAAGTGTGGTTTCAAAACACGCGCGCACGCGAACGCAAAGGGCAGTTTCGAGCGCATGCTCAAGTGATCAATAAGCGTTGCCCTTTCTGCCCGGCATTGTTCAAAGTTAAGTCTGCGTTGGAATCTCATCTTACAACAAAGCATGCCGATCAGTGTGCGCGCGGAGAAATCAACATTGATGCGTTGCCAGATGAGGAAGCTAGTCTCGAATCGTCGCCCAGCTTAAGCTCCGGCGGTGACAATAAGTTTGGTGGATTGGCAGCCAACATGATGCCACCTCTTTTTCCCAACTTGCACCCGGACATGGAAAATTCAATCAAGAAGTACTACGAGGAGAGCATGAAGAGATACATCAGTGAGCTGCAGGCGCACGCTTCAAATGGCGACAAAAGTGAAATCAAGGGAGAAGAAAAGGAAGAAGGCGGAGAGATCCCTTTAGACCTATCAAAACCAGTCGATTTGTCCCATCCAATGAAGGTTAACATGGATCACGAACGCAATTTGTGCGATCCTGGACCGTTGACCGACTTGAGCGAAAGATCTCTGTGTGACGAGCGCATGTCGGATTCAATGTCAGAAACTACCGACTTCATGTACGACGAGAGCAATCCAACTTCACCCGCTTCTAGTACTCAGAGCAACAACACACCCGCCAGGCCGCAAAATGCGACGAGCACACCAAACGCGAATTCCAACTCGAATAAACGTTTTCGCACGCAGATGACGGCGGTGCAAGTTAAAGTCATGAAAACTCTCTTCACCGACTACAAGACTCCTACAATGGCAGAATGCGAAATGTTGAGCAGAGAAATTGGACTTCCAAAGCGAGTGGTGCAAGTGTGGTTCCAGAATGCGCGTGCCAAGGAGAAGAAGAGCAAGATTGCGTTGCAGAAGGTCCTGGGCAACACTGATGCAGCTGAGAACACAACGCCCATCCTTCCGGACGATTGCAAATTTTGCGCCTTCAAGTACTCTCACAAGTACTCAATTCAAGATCACATTTTCACCAAGAGCCACATCAACAACGTGCGGACGCACCTCGAAAACGCCAGTAAGGACAACGCGAATGCCGAAAGCGGAGAATTCCAGGTTCCGCCCATTCCCGGCGCCTCCGTGTCTGCAGATTCTACCACCCATCCAGCAGGAGCCCAGCCAACGTTAAACAACAACACCCATCTGCAGCTACTTCAGATGGCCGGCATGCAAATGGCTGCAGCCGCAGTCAAAGGGGAAAACCAAGACGACAATAATCAGGAGGCGCTCTTCCAGCAGCTCTACGCCTTGGGCAATAGCGGCAACTTCGGCGGCCAGAATCAGTTCCTGCATCATCCGATGTTTGGCGCAAATGGTGAGTCCCAAAGTTGA
Protein Sequence: MPPRVFHCSLCSFSATNRLPLLQHVRSLKHLHLEQLHQLQRRAEGKETGPEIGEVFHVVPGPVDQSISERRDSVNSEQSNQAESNHQLSGKEFKSEPCDDEMVGGGGDAASGGAQHVCPYCDYASDSEMRIQAHVLAQHGTNHSSSESSFQCPLCQDAFKDRSSLERHVMQIHSVNSEGLQRLLMLVDQSHWLNRSPNHLNNAGGASGQLTSPTSVSSKDSKHTPDKASTPNHAVDLENELMSPTHSDDAGDVAEFERCATCMKSFKNIDELCYHQNETGHLEIKQTPSGPGYACWKKGCNQFFPTAQSLQMHFKDVHAKNSVTQMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHLIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELNAYKQSLMTNPLLLAGLQGQVLDSSTNDILKKESLRSDDAESVADGDDSKELSTSHDDSNANDGENSNDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQNYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQQNNNNNNPPVSPVTGGQSAVQAPGTPKSTSSNEDDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMAGQIDLSKPLIEQPDAAAVQSPKHASPTPGGGEKTSPTPPAASPVPSAGSAPAGSQGMMPTCPKCGALFSSSDQLSVHQQLYCMFAAPNMAIFQAHEPGTAKSPPPATAAGEQPQPNDAANRLSLPKRINSQMQKHLLESYGFDVVMHYNESQHRRRHQHAADESKRPTTASPPAAAADDSEATSRPAEDDTENNLPEVSKSTCQHCNKEFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKNEYEKKTVVVTAATSSTLNCNPRISSSPNAAVGGGNGGGEPTDKDDESKEALHAKLNLHTPPEAHSTAPSTPTSSSTTPASSTDSLPANIQAMIAQTMAQNPMAFAQQVSEMQAALNVMQLQQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPFDAMQQFAPQEQQAMMAKQQQAAMMQQQAAVSAAANQKRARTRITDDQLKILRAHFDINNSPSEEQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMVLNSSGSSAEENKSKESSPPPPFQAAEIKTELKEEPLDETNNEKHNETDEKPNIFNLPPHLQPPQSPASSMSSTDNNQHTSTSAPSTPNNLTLTSIIASQLGDNIITTNTPSQMNMTASPMLPPPKLNQQNYQTPNSTLQGMMPLTPNRCLSPNRDFASMNSNSNSSTGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPASEPSPGPAEQTPAATEGGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTIEQNNTQQPQTPGNQSQGPSHSPVQPNPSTTPTPSGQNTRPPSPSASPVDSKEGTFQCDKCNLVFQRFDLWREHQLVHIMNPTLFPSYPPDSPFGILQQHAQLQQLQQGVSDLSTLSDKSASPIPLPLINMLNNVTAQKRKLEEYDGESDVSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCARGEINIDALPDEEASLESSPSLSSGGDNKFGGLAANMMPPLFPNLHPDMENSIKKYYEESMKRYISELQAHASNGDKSEIKGEEKEEGGEIPLDLSKPVDLSHPMKVNMDHERNLCDPGPLTDLSERSLCDERMSDSMSETTDFMYDESNPTSPASSTQSNNTPARPQNATSTPNANSNSNKRFRTQMTAVQVKVMKTLFTDYKTPTMAECEMLSREIGLPKRVVQVWFQNARAKEKKSKIALQKVLGNTDAAENTTPILPDDCKFCAFKYSHKYSIQDHIFTKSHINNVRTHLENASKDNANAESGEFQVPPIPGASVSADSTTHPAGAQPTLNNNTHLQLLQMAGMQMAAAAVKGENQDDNNQEALFQQLYALGNSGNFGGQNQFLHHPMFGANGESQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00631327;
90% Identity: iTF_00631327;
80% Identity: iTF_00631327;