Basic Information

Insect: Earota dentata
Gene Symbol: topi
Assembly: GCA_027574905.2
Location: JAODGB020019184.1:1-3734[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.00019 0.019 15.6 3.0 1 23 50 73 50 73 0.92

2 20 8.8e-05 0.0088 16.7 0.2 1 23 77 99 77 99 0.98

3 20 0.16 16 6.4 0.1 1 21 107 127 107 128 0.95

4 20 0.0022 0.22 12.3 0.8 1 23 136 158 136 158 0.96

5 20 4.2e-06 0.00042 20.8 0.3 1 23 164 187 164 187 0.97

6 20 0.00048 0.048 14.3 5.7 1 23 197 219 197 219 0.97

7 20 0.0013 0.13 13.0 0.5 2 23 225 246 225 246 0.97

8 20 0.00012 0.012 16.2 0.5 1 23 252 274 252 274 0.98

9 20 1.4e-05 0.0014 19.2 5.9 1 23 280 302 280 302 0.98

10 20 0.0016 0.16 12.7 0.9 1 22 308 329 308 329 0.93

11 20 0.0026 0.26 12.0 0.9 3 23 365 385 363 385 0.96

12 20 0.00024 0.024 15.3 0.9 1 23 389 412 389 412 0.96

13 20 2.9 2.9e+02 2.4 0.2 1 23 419 442 419 442 0.92

14 20 0.0019 0.19 12.4 1.3 1 23 448 470 448 470 0.96

15 20 3.8e-05 0.0038 17.8 0.4 1 23 476 499 476 499 0.95

16 20 0.00056 0.055 14.1 4.3 1 23 510 532 510 532 0.97

17 20 9.8e-06 0.00098 19.7 0.5 3 23 539 559 538 559 0.97

18 20 0.00043 0.043 14.5 1.0 1 23 565 587 565 587 0.97

19 20 7.8e-08 7.8e-06 26.3 1.0 1 23 593 615 593 615 0.99

20 20 0.00068 0.067 13.9 0.2 1 21 621 641 621 642 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.00019	0.019	15.6	3.0	1	23	50	73	50	73	0.92
2	20	8.8e-05	0.0088	16.7	0.2	1	23	77	99	77	99	0.98
3	20	0.16	16	6.4	0.1	1	21	107	127	107	128	0.95
4	20	0.0022	0.22	12.3	0.8	1	23	136	158	136	158	0.96
5	20	4.2e-06	0.00042	20.8	0.3	1	23	164	187	164	187	0.97
6	20	0.00048	0.048	14.3	5.7	1	23	197	219	197	219	0.97
7	20	0.0013	0.13	13.0	0.5	2	23	225	246	225	246	0.97
8	20	0.00012	0.012	16.2	0.5	1	23	252	274	252	274	0.98
9	20	1.4e-05	0.0014	19.2	5.9	1	23	280	302	280	302	0.98
10	20	0.0016	0.16	12.7	0.9	1	22	308	329	308	329	0.93
11	20	0.0026	0.26	12.0	0.9	3	23	365	385	363	385	0.96
12	20	0.00024	0.024	15.3	0.9	1	23	389	412	389	412	0.96
13	20	2.9	2.9e+02	2.4	0.2	1	23	419	442	419	442	0.92
14	20	0.0019	0.19	12.4	1.3	1	23	448	470	448	470	0.96
15	20	3.8e-05	0.0038	17.8	0.4	1	23	476	499	476	499	0.95
16	20	0.00056	0.055	14.1	4.3	1	23	510	532	510	532	0.97
17	20	9.8e-06	0.00098	19.7	0.5	3	23	539	559	538	559	0.97
18	20	0.00043	0.043	14.5	1.0	1	23	565	587	565	587	0.97
19	20	7.8e-08	7.8e-06	26.3	1.0	1	23	593	615	593	615	0.99
20	20	0.00068	0.067	13.9	0.2	1	21	621	641	621	642	0.93

Sequence Information

Coding Sequence: GAAATTGATGATGTATTAACGCCAATTGTAACTATTTCTGAAGtcaaaaagaagaagcgaGGACGGCCCCGAAAATCCGACGCCGAAAAGCAGGCGGCCAAGGATGCCAAGCACGAGGTGAAAAAGGCGAAGGCAAAGAGCAGAATGCACTCGTGCGAGGTGTGCGGCAAGCGGTTCAAAACGAATCAGTTAATGAAGCAGCACGTGACGAACTTTCACTCGAACATTTACAATTGCAACGAGTGCGCCGAATCGTTTAACACGCCGCTGGAGTACTCGATCCACATACGCACGCACACGGAGGACACGAACCCGAACTTCCAGTGCGTGCTCTGCGACTACGAGACGGCGGCGATCGACGAGCTGAAGAACCACCTCAAGAAGTGCTCggaccgcgcgccgcgcttcacCTGCACCATCTGCAAGAAGGGCTTCAACGTGCGCACGTGGTACCTGGAGCACGCCAACTATCACACCGGCGACAAGCCGTTCGTGTGCGAGATCTGCGGCAAGGCGTTCATTTACTCGCGCTACCTGTCGGCGCACCGCTCCACGCAGCACAAGTTCAACGGCGAGGAGAAGAAGCTGCACCATTGCACGCTCTGCGATAAGGTCTATCAGCATCGAAACAGTTTGGCGATTCATATGAATACTCACACCGGCAATGGCGCCGTTTGCGATATTTGCGGTAAACTATTGTCAAGCAAAGAAAAGCTGAAATTCCATATGAGAATTCACAGTGGTTACAAACCCTTCAAATGCACTTACTGTGAAAAGGCATTTATTAAGAAAACCATTCTCGTTGagcacattcgcattcacacCGGCGAGAAACCCTATCGCTGCGAGTATTGCCATAAATGTTTCTCGCAGCGCAGCAGTATGGTGACGCACGTGCGCGGCCATACTGGCGAACGTCCGCACGTGTGTCACTTCTGCGGCAAGGGGTTCGTCGCGAAAGCCATGCTTAACTTGCACTTTAAAACTTGCAAAGGATACAACTATCCCCCTCAGCaGATTGTGTCGCAAAAGCGCAAGGGGGGCAGGCCAAGAAAGAACAAGGAAGTACCCTCCGCACAAGGAACGATTAATTGCGATGTTTGTTCCATGAAATTTAAGAGCGAGCGCGGCTTGCGCGTGCATTCCAAGAAGCACATTGGCAACTACAAATGCCCGCATTGCCCCGAGGGCTTCAAGAAGCCGGTCGAAATGATCATCCACAATCGGCACGTGCACGGCAAGGATAATGTGCCCTATGAGTGCATATTTTGCGATTACATGAGCGACAACCCCAACCAGATTGCGCAGCACGTGAAGAATACTCACGACAAGGTGCCGAAATACACGTGCACCCTCTGCAAGAAGGGCTTCAACGTGTACAGCTGGTTCACCGAGCACGCGAACTTTCACACCGGCGAAAAGCCCTTCGTCTGCGAGATGTGCGGCAAGGCGTTCCCGTACTCGCGGTACTTATCGGCGCATAAGACCAGCATGCACTTTGAGGATCAGCACGGGTACGCCAAGGTGCACGAGTGCCTGATCTGCAAGAAGACTTATCAGCACCGGAACAGCCTGCTGGTGCACATGAACTCGCACACGGGCAACGTGGCGATTTGTGATATTTGCGGCAAGACTTTATCCAGCAAGGAGAAATTGAAGCTGCATTACCGTATTCACACCGGTTACAAGCCCTTTAAATGTCAGTACTGCGAGAAGGCGTTTACGAAGAAGACAATACTGGTGGAGCACGAACGCATTCATACCGGCGAAAAACCTTATCAATGCGAATACTGCGAGAAGAGCTTCTCGCAGCGGACGAGTCTTGTGATTCACATCAGGAGTCACACGGGGGAACGGCCATATGTGTGTCACATATGCAATAAGGGTTTCGTTGCACGGGCAATGttgaatatacattttaaatcctGCAGGGGATTTGAGCAGCAAGTAAGTTAG
Protein Sequence: EIDDVLTPIVTISEVKKKKRGRPRKSDAEKQAAKDAKHEVKKAKAKSRMHSCEVCGKRFKTNQLMKQHVTNFHSNIYNCNECAESFNTPLEYSIHIRTHTEDTNPNFQCVLCDYETAAIDELKNHLKKCSDRAPRFTCTICKKGFNVRTWYLEHANYHTGDKPFVCEICGKAFIYSRYLSAHRSTQHKFNGEEKKLHHCTLCDKVYQHRNSLAIHMNTHTGNGAVCDICGKLLSSKEKLKFHMRIHSGYKPFKCTYCEKAFIKKTILVEHIRIHTGEKPYRCEYCHKCFSQRSSMVTHVRGHTGERPHVCHFCGKGFVAKAMLNLHFKTCKGYNYPPQQIVSQKRKGGRPRKNKEVPSAQGTINCDVCSMKFKSERGLRVHSKKHIGNYKCPHCPEGFKKPVEMIIHNRHVHGKDNVPYECIFCDYMSDNPNQIAQHVKNTHDKVPKYTCTLCKKGFNVYSWFTEHANFHTGEKPFVCEMCGKAFPYSRYLSAHKTSMHFEDQHGYAKVHECLICKKTYQHRNSLLVHMNSHTGNVAICDICGKTLSSKEKLKLHYRIHTGYKPFKCQYCEKAFTKKTILVEHERIHTGEKPYQCEYCEKSFSQRTSLVIHIRSHTGERPYVCHICNKGFVARAMLNIHFKSCRGFEQQVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00620709;
90% Identity: iTF_00620709;
80% Identity: -