Basic Information

Gene Symbol
-
Assembly
GCA_963669185.1
Location
OY769903.1:13014881-13020287[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 2.7e-05 0.0022 18.4 0.7 1 23 148 170 148 170 0.95
2 15 0.001 0.081 13.5 1.1 3 23 178 198 177 198 0.99
3 15 0.00014 0.011 16.2 0.1 1 23 349 371 349 371 0.98
4 15 0.032 2.6 8.8 0.1 1 23 377 400 377 400 0.97
5 15 8.8e-05 0.0072 16.8 1.8 1 23 428 450 428 450 0.98
6 15 1.8 1.5e+02 3.2 0.0 1 23 466 488 466 488 0.86
7 15 0.56 46 4.8 0.4 2 23 495 517 495 517 0.94
8 15 0.0024 0.2 12.3 2.8 2 19 525 542 525 546 0.95
9 15 0.00021 0.017 15.7 3.5 3 23 554 574 552 574 0.97
10 15 0.015 1.2 9.8 0.1 3 23 581 601 580 601 0.97
11 15 8.7e-06 0.00071 20.0 0.4 1 23 610 632 610 632 0.98
12 15 0.0038 0.31 11.7 0.2 3 23 640 660 638 660 0.97
13 15 0.0033 0.27 11.9 0.2 3 23 668 688 666 689 0.94
14 15 0.25 20 6.0 0.0 1 23 703 725 703 725 0.92
15 15 0.041 3.4 8.4 0.0 1 20 1126 1145 1126 1148 0.94

Sequence Information

Coding Sequence
ATGGACGTGTCGGGTGACTTGACGTTGCAATGGGTGGAGGAGGTTGGGAATGTAATTCACGAGGAGGTAATATGCGGCCTGGAGACGGAAATTCCAGCTccagaggaggaggaggaggtaaTAGGAGCTTGCGAGGAGGTATGCATGGAGGAGACTGTACAATCGGTGCCGGATCAAACAGCAACAGCCGACACGGAAATTATGATGGTACCTCAGCCCAGCGATATGGAATCGATCTACATAGTGCCCCAAGATCAGGGTCATGATTATCTCAATATTCAGGTCACCGAGGAAGTTATCACAGATAATTGGGACAGATCTGGTCCTGATgatggGGTCGAGATACCAGAGACAAAGGTCTCGCACGACAATTTGCTCGAGTATGACGACATGGAGATACCATTGCCGATTGATCAAGACtcgtacacaaacacacgtcCGTATCCTTGCGACTTTTGCAGTCGTAGATTTCGGAAAAAGGCAAATCTCATGAATCACATGGTGGCACATCAGACTGATCGTCCGCACGGTTGTAATTTGTGCGGTGCCCGTTATGTGAGAAAATGTGATTTGATGAATCATTTGAAGATTCACGCGTATGCCCCATCGCGGCACGGTCTTGAGGACGATTTGAACGATGAGGATTCGTTGGTACAGGATGAGGAGGAAACGACAAAGGGCAGACGAAAGAAAGTACAATCGAGCGCACCccgtaaacgaaaaaataatacagcaGCGGCAAAACGAGCcaatcaacaacaacaacaacaactgcaacaacaacaacaacagcagcagcagcaacaacaacaacaactcGAAGAGGcaacaaaaatgattgatacgaacAAATCTTATATAAATAAGTCGTACGATTATGTGGACGAGGATATGAGATTGTTGGAGGAAATGACGAGTAGAAGTACAAATATAAGAGCAGCCGGTAATTCTTACGCATCGAGCTCACGATGGACCGATGAAATATCACCGATCGATGCAGAATCACAACCGCCCCGATGGCCCATTACCGATCCGACAAAACCTTACGTTTGCCAATATTGCGGTGTTGGTTTTGCACGCGAAAAAGCTCTCGCTTCGCATTCTCGTATACATGGCGGTGATAGCCCGTTTGAGTGTACAAATTGTGGCGATATGTTCTGGGATGTTAACGCACTGCGTGAGCACATGAGGGTCAAACACGGTGGTCCAGCGTTGACAACGCCAAGTgacgaaattgaaaataacgaGGCAACGTACACCGGTGATGAGAGATTTGGCGAATTTTACTGTGATACATGCGGTGTACCGTTTCATCGTTTGGATCTTCTCAAACGTCACAGAAAaATACACATTAAGCAAGAAGTTACTGAGACGATGGAAGGTTCGAGTCAGCATCACGTTTGCAACGTTTGTGGCGAGTGGTTCGAGGAAGCTCTCGCTCTACTGGCACATGCTGAATTGCACGCGCGGTCGCCGACTCGTCGTTGTTTATTGTGCGGCGAGCGATGTCGCGATGATGCCGAGGTCGCCGAACACGTGAGACAAAATCACGCCGATGACGCCCCACCCAATACATGCACAATGTGCGGCAAAACTTGCAAAGACAAACGAAGTTTATTGAAACACTCGTGGGTTCACAATACCGATAAAACTTTCGGTTGCACCAAATGTGGCAAACGCTTTCACAGTAAAGCTCGGCTACGcagGCACATGGTGTCACATCGTAATAAAATGGTCGCTTGTGACGAGTGCGGCGAGGAATTTCCCGATGGCAGGGCACTCGTGAGTCATCGTCATTCGCACAACAAGGAACTCGGTGGGCGATCGTTTCCTTGCCGCGAATGCGGCAAAACTTTTGGCAGTCGAAGCTCCCAGCAGATACACATTCGCATACACACCGGTGAACGTCCATACGGCTGTAGATTTTGTTGGAAGGCGTTTGCTGACGGTGGTACATTGAGAAAACACGAGCGCATACACACCGGCGAGAAACCTTACGGTTGTGCGATATGCCCTCGCGCTTTCAATCAACGGGTTGTTCTTCGCGAGCACGTCAGAGCCCATCACTCAGGACCAGATCCAAAGTGTCATGGCAGCATGACGCCGTATCTGTGCAAAGTTTGCGGTGATTCATTTGGCACATCCGAGGAAATAGTTCTACACATAGTTCAGCATTGCGATGACAATACGGCATTGCGTCGTCAGCCACAGATAGGCCCCCGCAAGTACAAGCGAAGACGCAAGCTAAAGCCACACGAGCCAACAATTTCTCTGCCAGCTGTGAGATCGACAATGAACGAGAATTACAACGTTCTCGAGATTGCCTCAGACTCGGACGACAATACAAAACGAAAGCTCGGCCGTAAAAATAAGCAACAACATCGGTCAAATGTTGAGGATGGTTATCAAAATGTTCTCAAGAGTTTCGAGTCATCCctccaaaatataaattccatCGTCAgcaatacaaaattaaaaccCTCAAAATCCAAGGTTGCCAAGAAAAATGCAAAGAGCAAGATAAAAGGTGAGACgagcgaggagaaaaaaaccgAGACGCAGACATCAGGACAGCCAGGACGTCCAAAGATGATACACACGCAAAAAACTCGTGTACCCGTTGAAGTTGGAACTGACGGTGTGAAAAAAGGCCAAAAAACGAAAACTATGGTAACGAGAACACCAAAAGTTATGCCAAACGAGCACAAAATGTCACTTTTTCCCGGTGGTGAGAGAAATCGTCCAAGAACAAAGAACGTAAGTTATCACGTTGAGGGCAAGTTACAATTAACACCGGCTACATTCTCAAAACAAAAGGACGATAGTCCTTTAACCGGAAGTAGCTCCAacaacgataaaatttcaccaGGCACAAAGAGCTCTCAACAAACGAGCAATAAAAGATCAGCGGCCAATCACGCGACAAATaacaatggaaatttattggaTATTGATGATAAAACTGATAACGCTCCAGCGACATCGAAAAAACGTGTCCCTCCTGCAAAAAGaccaaaaaaatcacaaaaaaatattatgatcaAGCAAGAACCGATCGAACAATCATACGAGGATAATGAAATTCGCGATAACAATAATTCCGCTGATATCATGAATTCCAGTCGTTTTAGCAACGAACAAATTCTCATGGAACAGTCCAACTTTGAGCCGAGAATATTAAATGCCAGGGAAGAATCAATTTTGCCTGATCTCGATGATGATGTTAATCATGCTCGTAATATCGTTAATTCCggtaaaatgaaattaagCCTTAAAGTTGAAGCTACCACACCGAGAATCCTCATTGAGCCACGTGGTATCACAATTACACCTGCTGAGGATATACCAGAAACGATAATACCCGATACACTCGAGTATACGTGCGAAATGTGCGCAGCTGTTTTTGCTAGTCGTGCTGAATTACTCATACACGTACCTATACACATTTGA
Protein Sequence
MDVSGDLTLQWVEEVGNVIHEEVICGLETEIPAPEEEEEVIGACEEVCMEETVQSVPDQTATADTEIMMVPQPSDMESIYIVPQDQGHDYLNIQVTEEVITDNWDRSGPDDGVEIPETKVSHDNLLEYDDMEIPLPIDQDSYTNTRPYPCDFCSRRFRKKANLMNHMVAHQTDRPHGCNLCGARYVRKCDLMNHLKIHAYAPSRHGLEDDLNDEDSLVQDEEETTKGRRKKVQSSAPRKRKNNTAAAKRANQQQQQQLQQQQQQQQQQQQQQLEEATKMIDTNKSYINKSYDYVDEDMRLLEEMTSRSTNIRAAGNSYASSSRWTDEISPIDAESQPPRWPITDPTKPYVCQYCGVGFAREKALASHSRIHGGDSPFECTNCGDMFWDVNALREHMRVKHGGPALTTPSDEIENNEATYTGDERFGEFYCDTCGVPFHRLDLLKRHRKIHIKQEVTETMEGSSQHHVCNVCGEWFEEALALLAHAELHARSPTRRCLLCGERCRDDAEVAEHVRQNHADDAPPNTCTMCGKTCKDKRSLLKHSWVHNTDKTFGCTKCGKRFHSKARLRRHMVSHRNKMVACDECGEEFPDGRALVSHRHSHNKELGGRSFPCRECGKTFGSRSSQQIHIRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYGCAICPRAFNQRVVLREHVRAHHSGPDPKCHGSMTPYLCKVCGDSFGTSEEIVLHIVQHCDDNTALRRQPQIGPRKYKRRRKLKPHEPTISLPAVRSTMNENYNVLEIASDSDDNTKRKLGRKNKQQHRSNVEDGYQNVLKSFESSLQNINSIVSNTKLKPSKSKVAKKNAKSKIKGETSEEKKTETQTSGQPGRPKMIHTQKTRVPVEVGTDGVKKGQKTKTMVTRTPKVMPNEHKMSLFPGGERNRPRTKNVSYHVEGKLQLTPATFSKQKDDSPLTGSSSNNDKISPGTKSSQQTSNKRSAANHATNNNGNLLDIDDKTDNAPATSKKRVPPAKRPKKSQKNIMIKQEPIEQSYEDNEIRDNNNSADIMNSSRFSNEQILMEQSNFEPRILNAREESILPDLDDDVNHARNIVNSGKMKLSLKVEATTPRILIEPRGITITPAEDIPETIIPDTLEYTCEMCAAVFASRAELLIHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01057843;
90% Identity
-
80% Identity
-