Basic Information

Insect: Dynastes tityus
Gene Symbol: Zfa
Assembly: GCA_029618875.2
Location: JAROYD020000024.1:259255-260866[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 8.3e-05 0.0097 17.9 2.6 1 23 137 159 137 159 0.95

2 13 2.3 2.7e+02 3.9 0.2 7 22 171 186 166 186 0.91

3 13 0.004 0.47 12.6 9.1 1 23 192 214 192 214 0.98

4 13 0.09 10 8.4 0.4 2 14 221 233 220 234 0.84

5 13 0.00083 0.097 14.8 3.1 1 23 274 296 274 296 0.99

6 13 0.00034 0.04 16.0 3.3 6 23 305 322 303 322 0.98

7 13 1.1e-05 0.0013 20.7 0.2 2 23 328 349 327 349 0.96

8 13 2.1e-07 2.5e-05 26.1 0.6 3 23 357 377 357 377 0.99

9 13 4.7e-07 5.5e-05 25.0 2.2 1 23 382 404 382 404 0.98

10 13 1.4e-06 0.00016 23.5 3.2 1 23 409 431 409 431 0.98

11 13 0.00012 0.014 17.5 1.0 1 23 436 458 436 458 0.98

12 13 2.3e-05 0.0027 19.7 0.2 2 23 465 486 464 486 0.96

13 13 4.3e-06 0.0005 22.0 1.5 1 23 491 514 491 514 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	8.3e-05	0.0097	17.9	2.6	1	23	137	159	137	159	0.95
2	13	2.3	2.7e+02	3.9	0.2	7	22	171	186	166	186	0.91
3	13	0.004	0.47	12.6	9.1	1	23	192	214	192	214	0.98
4	13	0.09	10	8.4	0.4	2	14	221	233	220	234	0.84
5	13	0.00083	0.097	14.8	3.1	1	23	274	296	274	296	0.99
6	13	0.00034	0.04	16.0	3.3	6	23	305	322	303	322	0.98
7	13	1.1e-05	0.0013	20.7	0.2	2	23	328	349	327	349	0.96
8	13	2.1e-07	2.5e-05	26.1	0.6	3	23	357	377	357	377	0.99
9	13	4.7e-07	5.5e-05	25.0	2.2	1	23	382	404	382	404	0.98
10	13	1.4e-06	0.00016	23.5	3.2	1	23	409	431	409	431	0.98
11	13	0.00012	0.014	17.5	1.0	1	23	436	458	436	458	0.98
12	13	2.3e-05	0.0027	19.7	0.2	2	23	465	486	464	486	0.96
13	13	4.3e-06	0.0005	22.0	1.5	1	23	491	514	491	514	0.97

Sequence Information

Coding Sequence: ATGaCATGGGCAAAAGAAGATGTGCCTTCTTTTATTTGTGGAATATGTATAGAAAAACTAAGAATTGCctatgattttcaaacaatttgTTTACAATCAGATCGAGCAGTTCAATTACAAGCAGAAGCAAATGAAATACAAAGTTCTAGGAGTGTATCTCTAGATCCTATGACAACAACTGGCTTAGCAGGACGTGATGAAACAATAGAGAAAGTTATTTTAACTGTAAAATCGGAAGAAACAAAAGTGCAGCTTTTATCTCAATGTACCCCAGTTACCTCAGCTGCAACACAATTGGAAGCTACGCAGACAGTAATTAATCATCGTAAACATGGCTGCCAGCTTTGTTATATTAATGAATCCGGTGATCTAATGCATGAGATACATTCATACTCGGGAGAGGGACCGTTTGCATGTAGTTGTTGTGATAAAATGTTTGCTAGAAAATATCTGTTGAATGCACATTTAAAAACTCATACTAGCAATAAACTTTCACAATGTCAAATCAGTAACAAATCTTGTACAAAAGCTTCTGACTTTTCCATGCACATGAAGACACGCACTAGAGAGAAGTTCTGTTGTAAATTATGTGGTCTAAAGTTTACACAATGTTGTTCTTTAAGCGCGCATATGAAAAGACATGCTAGCGATAAACGTTGGCAATGTCAAATCTGTAAAAAATCATATACAAAATCATCTCTCCCATCAGCGTACACGAAGACACGTACTGGAGAGAAGTTCTGTAAATCACGTGGACAAAAATTTGCACATTCTGTTCAATTACCGGTCCGCATGCGGGAACACATAAGAAAACAACTATATAAATGCACCCTCTGCCGCAAAGTATACAATCATGCCCAAGAATTTGGAACGCATATGATGAAACATACTGGTGAGAAATTGACTTGTTCATGTGGTAAAAAGTTTAGCAGTAGATATAAGTTTAACCGCCACATAAAAACTCATACTGACGAAAAACTCAATTGCTCATATTGTGGTCGTATTTTTGCATATGTAAGCCAATTAAAGGTACATGTAAGAATGCACACTGGTGAGAAGCCCCTTGGCTGTGAAGTTTGTGGTAAAAAGTTTGCACAATCTTCCTCTTTAAATGTGCATATGAAGACACATACTGGACAGAAATATTCCTgcaaattatgtgataaaaaatttacacaatCTTCCCCTTTAAAGGTACATATGAAGAAACATACTGGACAGAAATATTCCTGCAAATTATGTGATAAAGAATTTACTCACCGTTCCTCTTTATATGTGCATATGAAGATACATACTGGACAGAAATATTCCTGTACATTATGTGCTAATAAGTTTACACAAATTTCCTCTTTAAATGCacatatgaaaagacatactGGCGATAAACCTTGGCAATGTCAAATCTGTAACAAGTCATATATAAGCTCTTCTCTGCTTGCATGGCACGTGAAGCAACATACTGGaaagaagttttcctgtaaattatgtgataaacaGTATACACGATCTGATACTTTAAATGCACATATTATGAAAAAACATAGTGGTGAAAAGCCTTAA
Protein Sequence: MTWAKEDVPSFICGICIEKLRIAYDFQTICLQSDRAVQLQAEANEIQSSRSVSLDPMTTTGLAGRDETIEKVILTVKSEETKVQLLSQCTPVTSAATQLEATQTVINHRKHGCQLCYINESGDLMHEIHSYSGEGPFACSCCDKMFARKYLLNAHLKTHTSNKLSQCQISNKSCTKASDFSMHMKTRTREKFCCKLCGLKFTQCCSLSAHMKRHASDKRWQCQICKKSYTKSSLPSAYTKTRTGEKFCKSRGQKFAHSVQLPVRMREHIRKQLYKCTLCRKVYNHAQEFGTHMMKHTGEKLTCSCGKKFSSRYKFNRHIKTHTDEKLNCSYCGRIFAYVSQLKVHVRMHTGEKPLGCEVCGKKFAQSSSLNVHMKTHTGQKYSCKLCDKKFTQSSPLKVHMKKHTGQKYSCKLCDKEFTHRSSLYVHMKIHTGQKYSCTLCANKFTQISSLNAHMKRHTGDKPWQCQICNKSYISSSLLAWHVKQHTGKKFSCKLCDKQYTRSDTLNAHIMKKHSGEKP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -