Dtit037614.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Dynastes tityus
Gene Symbol
-
Assembly
GCA_029618875.2
Location
JAROYD020000009.1:5527242-5546418[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 5.1e-05 0.0059 18.6 5.1 1 23 136 158 136 158 0.98
2 20 3e-06 0.00035 22.5 0.2 1 23 164 186 164 186 0.96
3 20 0.0048 0.56 12.4 0.7 1 23 192 215 192 215 0.96
4 20 0.016 1.9 10.8 2.7 1 23 225 248 225 248 0.97
5 20 2e-06 0.00023 23.0 0.5 1 23 335 357 335 357 0.98
6 20 7.6e-05 0.0088 18.1 3.4 1 23 363 385 363 385 0.99
7 20 0.048 5.6 9.2 4.8 1 23 391 413 391 413 0.98
8 20 0.0022 0.26 13.4 0.6 1 23 424 446 424 446 0.98
9 20 0.00018 0.021 16.9 3.6 1 23 501 523 501 523 0.99
10 20 2.1e-05 0.0024 19.8 1.7 1 23 529 551 529 551 0.98
11 20 7.6e-05 0.0088 18.1 1.1 1 23 557 579 557 579 0.98
12 20 0.0068 0.8 11.9 3.0 1 23 585 607 585 607 0.98
13 20 2.5 2.9e+02 3.9 0.4 2 21 944 963 943 964 0.88
14 20 4.6e-07 5.4e-05 25.0 1.3 2 23 1054 1075 1053 1075 0.98
15 20 1e-06 0.00012 23.9 4.1 1 23 1081 1103 1081 1103 0.99
16 20 0.0062 0.73 12.0 5.3 2 23 1112 1133 1111 1133 0.96
17 20 0.0022 0.26 13.5 4.1 1 23 1139 1161 1139 1161 0.98
18 20 0.00016 0.018 17.1 5.6 1 23 1268 1290 1268 1290 0.98
19 20 2.7e-05 0.0031 19.5 0.9 1 23 1294 1316 1294 1316 0.98
20 20 0.0013 0.15 14.2 2.0 1 23 1322 1345 1322 1345 0.97

Sequence Information

Coding Sequence
ATGctaaaaatttaccaaaaattaTTGAAGTCGGCTGAAAAGTGGTTTGGTGATGTCAACACAAATTGGGTGCTGCAGGAGGACGACGATCCAAAGCATCGAAGTCGGTTGTGCACCAACTGGAAACAGGAAAAAGACATTCAAGTCTTAGATTGGCCGTCTCAGTCTCCAGATACGAacccaatcgaaaatgtttggtcCATTGTCAAACGAAAGCTTGTAGGGGATCGTGTGACAGCTTTGAAACGGTTAACTGCGCGCATTCGTGAGATATGGAGATCGCTGCCGGAATCCCTTGCTGAAAAGTTCGTAGACAGCATGCGGACGCGATGTGAAGCCATAAAGAAGTTAGTTTTTAACCCAAAGAGAACTAGAAAACGTACAACTAATAATAAGGAATATACTCATAGATGTTCAGTATGCAGTAAATCGTTTCCCAAGAAATGCCTCTTGGAGAGGCACATGAGGATTCATAATGGTGAAAAACCATTTGCCTGTCCGAAATGTGATAAAGCTTTCGCTCAGAAAAGTACCCTTCAAATACATTTAGTGAAACATTCGGGTCACAAACCATATAAATGTACCTTATGTTCTGCTGAATACTTCCAGAAGGGAAACCTTCGGGTACATGTTGAAAAAACTCACACAGCTCCCCCTAATATtgataaaatgtacaaatgcaCTCAATGCACTTGCATATTTAGAAGAATCGGCTCTCTCAACGGTCATATAACTAAAACACATGGAAGTATTAGAAGTGAAAAATCCATCGATGAGTTTCTGGATACTGATGATAGAGTGAGAGTTCTTAAAGAAATGGCCGAGCAGATCATGTCAAAACCTTCCAATGAAAACAgagaaatagaaaaatcaacagaaaaagAGAAAGATCAATTAGATGTGACAACcaatgaaatatttgtaaaattagcGGAAAATAGTGTAGACGGATCCATGAGACGATATATCGTGAAACAACGAAAAGTTGGGGACATGAAATggtttatttgtttgtattgcAGTAAAGAATTTAAGAAACCGTCAGATTTAATAAGGCATATCCGAATTCATACTAGAGAGAAACCATACAAGTGCAAAACTTGTAATCAGTGTTTTGCTTTGAAATCCACTCTATTAGCACACTTGAATACGCATGAAGGAAAAAGAGATTTTCAATGTTTAATATGTTGCAAATTTTTTACTTCATCCAAGACGTTAAGTGTGCATGTAAAGAAACATAGTAAAACTGGATCCGTACCCTCCTTGAAATACAAATGTTCAACTTGTAATAAACTCTTTGGTACCCTTGCGAAAGTTAGAAATCATATGGAAGTTCACAATTGTCCTAATgacgacatagaactgaattGTGGTAGACAAGAACAATCTGAAGTTACTTTAAAACCACCGATGATAGAGACTGATCAAGGTTTGGTATCGGTTCCTGCTCTCAAACCAAGGATACCCCATGGAGATATGGAAGAGTACAAACATAGGCCATACAAATGCCATAAATGTAATGCGGCGTTTATGAAACCTGCTCATGTAAAAAGGCATATGTTAACGCACTCTGGCGAGAGAAATTTTAAATGTGATTTATGTTCAAAGTCATTTTCCACATCTTACGCTCTGAAGGGGCACATAAAATTTCATGATCCTGAGAAGAGATTTACTTGTACTCTATGCCCCAAGAAATTCGTAGCGAAGGAATTACTGAAGAAACATCAAATAAAACACTCAACAGTAAGGCCTTACATTTGTCCCTATTGCAGAAGGAGATTTAAAACTGCTGCATTTTGTCGtaaacatataaacatacacAGAAATGACAAGAGTGTATTAACTGATAGTTTGGAGACACCTGCAAGTAATCCTGCTAAAATCATTAATCTCTCAACTACGTTATCGGATAACCCCTTTGATTTGGAGACACCAATGGATGGTGGAACGATATTTCTTAGATCTCAAGATCCTGACGAACCAAAGCCAATTGAGAATATAGTAACGGAATTACCGTCATTTGTGCAAAACAAAGCAATGAAAGGTAAAGCAAAAGCAAAGAAACCTCAAAATACAAAAGAGGAAACGGATGAAAGCGCGACTAATTCTTATGATCAGGATGTATTGAACTTACCTAGGAATGCTCAAATATTTGTCTCGAAAGAAGGACATTATACTATTGTAATGCCAGAGCAAAATGAGGTTGAAGTTACTACCGTTAACTCTAATATAGAAGAAATTGATCAAAGTGCTACAGAGTTTGTTAACTACGATGAATATCCATCAGTTAGTAACGATGTGTATAATACATTGTTATCTAGTGTTAAGCTACAGAACAATGATCCCATCTTAATGAGTACCATTGGAGAATCTCAAGACGCTAACATATTATTCATGGATCCGACATTGTCGCAAACCGCCGAATTTCCAAGCGAAGCTCAAAATTTCGAATCTTTTAATCCAACGATTTTCAACACCGCCGTTGATTTACCTCTAGGCGTCCAATCGGCCAATGTAAATTCAACATTCACCCAAAACACGCAGTCCATACTGTCATCTGCCACACACGATGGGAAATCAAGCAATTTAAAGCTAAGCTTCCCGGAAAATGTGAATATACAAGCCGATGCGAATAAGAAGACTTCTCATACGGTTGATACTTCGAAGTTGCTGTTAGCCTCAGAGCCTATGAATTTAAGCGATAACTTGATTATCACTCTGAATGGAGATGAAATTCCCGGCatgaatttcaattttaataatggCCTAAACGTTTCTGCtgacaatttaaatttgaatattatcgATAACGAGATACAGAATAGTCTTATGTGCACTATTTGTAAAGCAACGTTCGAGAATGGTAGTGAGTCAGAGAAACATCAATGTATTGAGCCGATCTCGGCTGAGCTACATGAGAATGATACCGATGATAGTATGAACGCAATGGATCTTAACGGAGACTTGGCAAACATCCAGCAGGATGAGCAAATTACTCTAATTACAGATTATAATGACCAGCTTCAAACTACTCACGTGGAAATTTCAACCGATGAGCCTAGTATTGATTCGCCCATCATCAAAGAAACAGGGAATGATAGTGAAGATAGCAAAGCAACTATGCATTATGGAAGGGATAGATCGAAGAAACCTGACAATAAGTGTACTTATTGCAGTAAAGCGTTTAAAAAGGCTTCAGATCTGatTCGCCATATAAGAACCCATACAGGGGAGAGACCGTTTACttgtaataagtgtaataagAGTTTTTCACTTAAATCTACCCTGCAATCTCATCAAAGAACACATAGTGATATAAGAAGTAGAGACTGTGTTTGTACAGTTTGTAATTATACTTTTAGCTGTCGTGCCACTTTAAAAACTCACATGCGTATTCATACAGGTGCAAAACCTTATGCGTGTAATCTTTGCCATATGAAATTTAGAACATCATCCAGTAGAAAGTCTCATTTACTCACTCATGCCAAGCAGTCGAGAAGGGGTGAGTTGACGAATCGCTACGAAGAACTTCCTACAACGAACGATTCTACGAATTTACAACTTACCTTTGATAGTACAAATGCCACTGttgaaaatACAGAGAACAACGAAGTTCAACATATAGAAGGTGTATCTATGGATCTACTCCAACAGTTACAAAACGCTGGTTTTCTCTTCACGGAAACCAGCAACGACGTATTAGGCGATGGGCTGATGCAATTGAATTACGATACAACGCACTTGAACATTATAGATTCAAATATCCCCGTTTCAATCGAGGAtggacaaaaattgaagaaattcgAATGCAATTTTTGTCATAAAACGTATACTACCAAAGCAGTCCTAAGGAAACATCAAAAACGACATAAAAAGGCCTTTCAATGCACTAAGTGCGATAAGCAATTCGACTCGGAGGATTTATTAGAGAAGCATGTGAAATTACATTCGGGATATAGACCGTTTTCATGTACCCATTGCGCTAATAGCTTCAGCGAAGAAGGAAGCTTGAAGACACATATGAAGCGgatCCACAACGTATATTAA
Protein Sequence
MLKIYQKLLKSAEKWFGDVNTNWVLQEDDDPKHRSRLCTNWKQEKDIQVLDWPSQSPDTNPIENVWSIVKRKLVGDRVTALKRLTARIREIWRSLPESLAEKFVDSMRTRCEAIKKLVFNPKRTRKRTTNNKEYTHRCSVCSKSFPKKCLLERHMRIHNGEKPFACPKCDKAFAQKSTLQIHLVKHSGHKPYKCTLCSAEYFQKGNLRVHVEKTHTAPPNIDKMYKCTQCTCIFRRIGSLNGHITKTHGSIRSEKSIDEFLDTDDRVRVLKEMAEQIMSKPSNENREIEKSTEKEKDQLDVTTNEIFVKLAENSVDGSMRRYIVKQRKVGDMKWFICLYCSKEFKKPSDLIRHIRIHTREKPYKCKTCNQCFALKSTLLAHLNTHEGKRDFQCLICCKFFTSSKTLSVHVKKHSKTGSVPSLKYKCSTCNKLFGTLAKVRNHMEVHNCPNDDIELNCGRQEQSEVTLKPPMIETDQGLVSVPALKPRIPHGDMEEYKHRPYKCHKCNAAFMKPAHVKRHMLTHSGERNFKCDLCSKSFSTSYALKGHIKFHDPEKRFTCTLCPKKFVAKELLKKHQIKHSTVRPYICPYCRRRFKTAAFCRKHINIHRNDKSVLTDSLETPASNPAKIINLSTTLSDNPFDLETPMDGGTIFLRSQDPDEPKPIENIVTELPSFVQNKAMKGKAKAKKPQNTKEETDESATNSYDQDVLNLPRNAQIFVSKEGHYTIVMPEQNEVEVTTVNSNIEEIDQSATEFVNYDEYPSVSNDVYNTLLSSVKLQNNDPILMSTIGESQDANILFMDPTLSQTAEFPSEAQNFESFNPTIFNTAVDLPLGVQSANVNSTFTQNTQSILSSATHDGKSSNLKLSFPENVNIQADANKKTSHTVDTSKLLLASEPMNLSDNLIITLNGDEIPGMNFNFNNGLNVSADNLNLNIIDNEIQNSLMCTICKATFENGSESEKHQCIEPISAELHENDTDDSMNAMDLNGDLANIQQDEQITLITDYNDQLQTTHVEISTDEPSIDSPIIKETGNDSEDSKATMHYGRDRSKKPDNKCTYCSKAFKKASDLIRHIRTHTGERPFTCNKCNKSFSLKSTLQSHQRTHSDIRSRDCVCTVCNYTFSCRATLKTHMRIHTGAKPYACNLCHMKFRTSSSRKSHLLTHAKQSRRGELTNRYEELPTTNDSTNLQLTFDSTNATVENTENNEVQHIEGVSMDLLQQLQNAGFLFTETSNDVLGDGLMQLNYDTTHLNIIDSNIPVSIEDGQKLKKFECNFCHKTYTTKAVLRKHQKRHKKAFQCTKCDKQFDSEDLLEKHVKLHSGYRPFSCTHCANSFSEEGSLKTHMKRIHNVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01499044;
90% Identity
-
80% Identity
-