Basic Information

Gene Symbol
-
Assembly
GCA_951804985.1
Location
OX638130.1:86873919-86876819[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.0016 0.21 13.1 2.7 1 23 403 425 403 425 0.98
2 9 0.00017 0.023 16.2 5.7 1 23 459 482 459 482 0.96
3 9 8.9e-07 0.00012 23.3 0.1 1 23 488 510 488 510 0.98
4 9 3.8e-05 0.005 18.2 5.3 1 23 516 538 516 538 0.97
5 9 0.9 1.2e+02 4.4 8.9 1 23 566 588 566 590 0.92
6 9 0.00088 0.12 13.9 1.4 1 23 594 616 594 616 0.97
7 9 0.00013 0.017 16.5 6.1 1 23 622 644 622 644 0.98
8 9 1.5e-06 0.0002 22.6 0.7 1 23 650 672 650 672 0.98
9 9 0.0084 1.1 10.8 0.1 1 23 678 703 678 703 0.89

Sequence Information

Coding Sequence
ATGTCCTTAGCTATATGTCGTATTTGTGGAGCAAAAGACAATCTGATGCACGTCTTACAAGGTGGCCAAGAATTGCTGCAAAAATTGAATCTCTGTGCAAACATTAAGATTGATTTCGAGGATGATCTGCCAAAGCACCTTTGCCTGCAATGCGAACAGTCGCTCAATCTCGCCTATCGGCTCCGCAAACAGGGAGAGGCAATGAACCAGAAGCTGCGCCAACAACAGGACTCCAATAACATCGTTCACGATCTATGTGATGAGGTGGATGACATCGAGGACGAGTTGCTGGAGTTTCGAgtgaaacacaaaaacaaagatgCACCTAGTGTTAGTGTTGTCGCCGCTGATGAAGATGTCCAAGTAGTGcagaataataatttggcgAAAGTGAAACCAGTGGCTGCTAAAAATGTTCTAATGTGTATCGATCCTAAAGTAAGCAATAACTACTTGAACAATAGTGACTACAGTCCATTTCATATAATAAACAACAAAGTGGTTAATTCCATAAAGAATTGCAGTGTAAGATTAAAAGTAAATGCAgatacacaaattgaaaatatgccCACGAATGCGGACATTTTGGAACAGTTTTTGCCTATGTCTATGGAGGAACAGGCGACACAGCAATTGGTGCCAAGCGAATTGAACAACAACGCACAGGATGAGGTGCAAATTGTCGCTGAGTATGTGGTAGCGAAAACGCTAGAATCAACTGTACAAGTTGTTAATACACAAACAGTCGACGACTTTACTTTGCAGAGTAACACAAAAAACGTCGAACTATCATTGTCGAAAACTACAGCATGTTATAATTTCGTACAGCAAGAGATAGACGATGATGTGCAAATAATTGAAGATTTCACTGAAAACGTTGCAGTATCAGTAGTAGAAACTGAAAGTACAGCATACGACATGAAGATGCCGGAATATGGAAATGTGTTGCCTTTGTCAGAAAATGaaaatgtacaaatggaaccaccaAACGATGATGATGGTAATAAGATCATAATGACGCACGATGATGCCAATATTGAAGAAGAACTTATTGAGGAAAGCCTTTTAATTGAGCCAAactatgccaactttgagacagAAGAAAAATATAGCATCGACTTAGTGGATGATGTGATTGTCATTGATGGCGATGAGGCAGAGCAGGAATGTGTTAAAAATGGTGGCACTCAAAAGCTTTATACCCAATACAAATGCGACACTTGCGCCGAGATCTTTACAAGCCATACTGAATATCGTACGCACATCAAGCAGCACGGTAGTGAGCGCTTCCATTGCATACAATGCAACAAATGGTTTCCGGCGCGTTATCGTCTGTTACAGCACGAACGTGTGCACAATACCACCCTGGAGATGCACTGTTGTTCTTACTGTAAGATCAATTACAGATATCGCTCGAATCTGATGCGTCACATACGTTCCGCCCACAGCAAGGAGAAGACATTTCCGTGTGAGGAATGCCCGGAGATATTCACGCGACCTGATACTCTGAAGGTGCACATGTTAAAGCATACGAACGAATGTAAATTTGACTGCGATCAGTGCTACAAAACtttcAAATCTCAAATGCATCTGAAGGTGCACAAAAGAACGCATTTAACAAGCACTTCCACCACTTCCACCACTTCCACCGACACTTCGGGCAGTTCACCGCAGCACACGGGCAAACAGCGCACTTATCATTGCGACGAGTGCGGCAAAATTTCCAAGCACCATTTTGCCCACAAGAATCATCTGCGCACGCACACGAGAGAGCGGCCGTATACGTGCCAAATGTGCGGCAAACATTTTCGCACTATAGCGGCGCGCTTAACTCACGAACGTATACACGGCGATACGCGTCCCTATCACTGCAAGCGCTGCTTTATCACTTTCCGGCAGTCGTCGCATCTGAAGGACCACATGTTGATACACGATGGTATTATGTCCTTTGTCTGTAGCGTCTGCAGCATGGCCTTCACCAAGAAAAGCAACATGAAGGTGCATATGCGCATTCACACCGGTGAGCGGCCGTACGCTTGCGCGGAGACCACGTGCGGTGAACAGTTTGCCAAGTTGGCGCAACTCAAACGTCATGCAGCGAAGGCACATGCGCGCGACGTTGATGTGGCGCCGGGCGAAGAGAATGATGATGACGAGGACGAGGGGGAGGACGATGTTGAGGAGATTGATGACGACGATGAGGGAAACGATACAGTGCAAGAGCAAGCGCAATTGGATTTGATGGACGATGAACTCGATACAGAATGTGCCGACGATGAGCTAAGCGATCGTCGTGCTTCTGCGGAAGCCGCTTGCTTTAATGCCATTATCAATGACGATGACCTAGATGTTGGCATTGGCGCCGAGGAGACCGCAACAGAGCTGCTTGTGACCAACGAGGCGGGATATGACTGTATCTACGATCTTATAAACTGA
Protein Sequence
MSLAICRICGAKDNLMHVLQGGQELLQKLNLCANIKIDFEDDLPKHLCLQCEQSLNLAYRLRKQGEAMNQKLRQQQDSNNIVHDLCDEVDDIEDELLEFRVKHKNKDAPSVSVVAADEDVQVVQNNNLAKVKPVAAKNVLMCIDPKVSNNYLNNSDYSPFHIINNKVVNSIKNCSVRLKVNADTQIENMPTNADILEQFLPMSMEEQATQQLVPSELNNNAQDEVQIVAEYVVAKTLESTVQVVNTQTVDDFTLQSNTKNVELSLSKTTACYNFVQQEIDDDVQIIEDFTENVAVSVVETESTAYDMKMPEYGNVLPLSENENVQMEPPNDDDGNKIIMTHDDANIEEELIEESLLIEPNYANFETEEKYSIDLVDDVIVIDGDEAEQECVKNGGTQKLYTQYKCDTCAEIFTSHTEYRTHIKQHGSERFHCIQCNKWFPARYRLLQHERVHNTTLEMHCCSYCKINYRYRSNLMRHIRSAHSKEKTFPCEECPEIFTRPDTLKVHMLKHTNECKFDCDQCYKTFKSQMHLKVHKRTHLTSTSTTSTTSTDTSGSSPQHTGKQRTYHCDECGKISKHHFAHKNHLRTHTRERPYTCQMCGKHFRTIAARLTHERIHGDTRPYHCKRCFITFRQSSHLKDHMLIHDGIMSFVCSVCSMAFTKKSNMKVHMRIHTGERPYACAETTCGEQFAKLAQLKRHAAKAHARDVDVAPGEENDDDEDEGEDDVEEIDDDDEGNDTVQEQAQLDLMDDELDTECADDELSDRRASAEAACFNAIINDDDLDVGIGAEETATELLVTNEAGYDCIYDLIN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-