Druf004889.1
Basic Information
- Insect
- Drymonia ruficornis
- Gene Symbol
- ZEB2_2
- Assembly
- GCA_947859195.1
- Location
- OX401917.1:9785348-9789382[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.012 0.71 10.5 3.8 1 23 199 221 199 221 0.98 2 10 3.4 2.1e+02 2.8 5.3 1 23 225 247 225 247 0.95 3 10 0.00051 0.031 14.8 3.8 2 23 251 273 250 273 0.96 4 10 0.00066 0.04 14.5 8.2 1 23 276 298 276 298 0.94 5 10 0.0034 0.2 12.2 5.1 1 23 302 325 302 325 0.96 6 10 1 60 4.5 0.2 3 21 335 353 334 358 0.90 7 10 0.0016 0.093 13.3 1.0 2 23 372 394 371 394 0.94 8 10 1.1 63 4.4 3.7 1 23 400 423 400 423 0.89 9 10 8.7e-05 0.0052 17.2 0.2 3 23 434 454 433 454 0.99 10 10 0.0009 0.054 14.0 1.7 1 23 460 483 460 483 0.96
Sequence Information
- Coding Sequence
- ATGTATGAAACTCAAGACATAAAGTTAAACTTTGTAAATAAGTGCAAAACATCGTACTGTCAAGCATGTCTCAGCGCTGATCGTACACTTTCATCATTAAACGAATACATCGATATTTATAAGAATATCTGCGATATTTCCTATGCTAATATCCCAAATTCATTATCAAGATTAACCAAAACCTACACAGATGATGCCATATTCATCACCTATGATGATGAAGTAAAACCAGAACTAAATATTAAACAAGAAATAGATCAAACTGATGATAGTTTGGACAATTTCGAACCACTCAGTGATGATTACCCTTTACAAGACATAAAAAAAGAAATTATAAAACATAATAAAAAAGAACAAAAAAATAAACTACAGCACTATAGATTTGTCTATGATTCAGATGTTAGAAAAAAGAGTTTGCTAAGAAAAAAGTTCTGTATCAAAGAGAGTGAGATAGAGTTATGGTTGGAGAAAGAGAGAAGTAGTGAGTTTTATAAGAAGTTTAAATACAAATGTAAATATTGCTTGCAAGGGTGGAATTTGAAGGAGAAACATGATGTGCATAATTCAAAATATCATGATGAGTCAATCGGACCCCATACCTGCCAGCTCTGTAGCTACCGTTTCAAGACTGAGACCGCGCGGTCTTTGCATATGCAAACACATTTTGTAGGCTATGCATGCTCATGCTGTGGGCACCAGTGTTATACAGCCCGAAGACTCAACGCACACCTTGATACACACAGAAAAGTGCAGTGTGTGTACTGTGAAACATGTTTCAGGGATCCAGCGCAGTTCCACAAGCATTATAAGTCTATGCATAGTGTATTTCTGTGTGATCATTGCGGCAAAAGATGTAAATCGAAGAATATGCTCGAGAAACATATGAGCCACCACTCCGACAGCCACACGTGCAACGCATGCCACAAGCGATACAAGTCGCTCGCGGCGCTTCGGAAGCATTACTCGATGAAGCACCGCTCAACGCTCGCCGAGCAAGCGTACTGCGTGCTCTGCGACAAGCAATACGATAACGTGTTTGTGTACAAACGGCACGTGCAAAGCAGCGCTGCGCATGCTCATGAGCGGGACCACGCCCGAGGCAAGAAATCGATATCATGTCCAGAATGCGGGAACACGTATTCAAGAAGGATTTACATGATGAACCACTACAAACACGTGCATATGAAGCAATCCAAATACTATTGCAGGGACTGTGATAGACATTTTCTAAATCGTACTAGATACGTTGATCACGTGAAATATAATCACGAAGGTGTAAAGAAAGAGAAGAACAAACTATGCAATATATGCGGAAGAGGCTTTGCTACTAACCGTATTCTGATAAATCACATTCGGACTCATTCTGGCGAACGTCCTTTTGAGTGCGAGTCCTGTGGCGCGAAGTTTACGCAAAAACACTCCATGCTATCACATGTTAAATATATACACTTGAAAAATTCAAGGCGGCCACACTGCCATTGA
- Protein Sequence
- MYETQDIKLNFVNKCKTSYCQACLSADRTLSSLNEYIDIYKNICDISYANIPNSLSRLTKTYTDDAIFITYDDEVKPELNIKQEIDQTDDSLDNFEPLSDDYPLQDIKKEIIKHNKKEQKNKLQHYRFVYDSDVRKKSLLRKKFCIKESEIELWLEKERSSEFYKKFKYKCKYCLQGWNLKEKHDVHNSKYHDESIGPHTCQLCSYRFKTETARSLHMQTHFVGYACSCCGHQCYTARRLNAHLDTHRKVQCVYCETCFRDPAQFHKHYKSMHSVFLCDHCGKRCKSKNMLEKHMSHHSDSHTCNACHKRYKSLAALRKHYSMKHRSTLAEQAYCVLCDKQYDNVFVYKRHVQSSAAHAHERDHARGKKSISCPECGNTYSRRIYMMNHYKHVHMKQSKYYCRDCDRHFLNRTRYVDHVKYNHEGVKKEKNKLCNICGRGFATNRILINHIRTHSGERPFECESCGAKFTQKHSMLSHVKYIHLKNSRRPHCH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -