Basic Information

Insect: Drymonia ruficornis
Gene Symbol: Zeb1_1
Assembly: GCA_947859195.1
Location: OX401917.1:9615947-9634015[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00026 0.015 15.8 1.7 1 23 222 244 222 244 0.99

2 12 0.13 7.5 7.3 0.0 2 23 252 274 252 274 0.95

3 12 0.76 46 4.8 8.1 1 23 278 300 278 300 0.98

4 12 0.00064 0.038 14.5 3.5 1 23 305 328 305 328 0.97

5 12 0.00014 0.0084 16.6 0.4 1 23 332 355 332 355 0.96

6 12 0.0041 0.25 12.0 1.5 1 20 366 385 366 387 0.95

7 12 4.4e-05 0.0026 18.2 2.4 2 23 399 420 398 421 0.94

8 12 0.00014 0.0081 16.6 1.1 2 23 427 449 426 449 0.96

9 12 1.5e-05 0.00088 19.7 0.9 2 23 468 489 467 489 0.97

10 12 2.3e-05 0.0014 19.0 0.7 1 23 495 517 495 517 0.99

11 12 2e-05 0.0012 19.3 3.8 1 23 523 545 523 545 0.94

12 12 5.2e-07 3.1e-05 24.2 3.1 1 23 551 574 551 574 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00026	0.015	15.8	1.7	1	23	222	244	222	244	0.99
2	12	0.13	7.5	7.3	0.0	2	23	252	274	252	274	0.95
3	12	0.76	46	4.8	8.1	1	23	278	300	278	300	0.98
4	12	0.00064	0.038	14.5	3.5	1	23	305	328	305	328	0.97
5	12	0.00014	0.0084	16.6	0.4	1	23	332	355	332	355	0.96
6	12	0.0041	0.25	12.0	1.5	1	20	366	385	366	387	0.95
7	12	4.4e-05	0.0026	18.2	2.4	2	23	399	420	398	421	0.94
8	12	0.00014	0.0081	16.6	1.1	2	23	427	449	426	449	0.96
9	12	1.5e-05	0.00088	19.7	0.9	2	23	468	489	467	489	0.97
10	12	2.3e-05	0.0014	19.0	0.7	1	23	495	517	495	517	0.99
11	12	2e-05	0.0012	19.3	3.8	1	23	523	545	523	545	0.94
12	12	5.2e-07	3.1e-05	24.2	3.1	1	23	551	574	551	574	0.98

Sequence Information

Coding Sequence: ATGGAGGAGCCGTTCGCCTGCCGTGTTTGTCTCGTTACTGACGTGACCCTGTATTATATGCACGATAATGGCTTGAAAACGGCGTATGAAAATCTTACCGGAGTTGTTATGATGCCAGACAGTCTACCGCAGTATCTATGTGCATACTGCTCAGCATTGGTCAGAAAATGTGTTGCGTTCAAGGAGAGGTGCCTGAGAAGCCAGGAATTACTTAAATATACTGTAATGCATCAACAAGTGCTAACTACAAACTACATACGAACTATAGACAGAGCATCCCACCAAATAATCCTACCGTACACCATCGTTAGTACCCACAAAGAAACAACAGATGGAGACACTATAAAAGAGGAAAATCTATTCGATTCCAATTTAATCAAAACCGAAGACAACGAAGTGAGTGATGAAGAGCCGTTGTCCAGAAAAGTTGAGAAAAAAAAGAAATTAAAAAACCAAGTTGAAATCAAACAAGAGTTTGATGAAATTGATTTTATTGATAATCAAATTGATAGCACTGATAACTTTGATGACACGACTGTCGGAGAAAACGTCATCTATGACAGATCGACGGAGAAAGAGATAGATATGATGGTGTTGACGAAACAGCAACAATTAGACGAAGTATTGGCGCGAAAGGATTCTTATAATTATCAGAATTCCTTTTATAAGTGCGATAAGTGCTTCAAGGGGTTTGTGACTGATGTCACTTACAAGAATCACATGATCAGACATGATTCCTCGTCTGGGCCGGAAGTATGCGAGATCTGCCAGACGCGGTGGGTGGACGCGCGCTCGCTGCGCGCGCACGTGGCCACCAGCCACCAGCGGCGGTACTCCTGCCGGCTGTGCGACCACACCTGCAAGAGCAGCCACAAGGCTAAGGAACATCAAAAGTGGCACAGCGGCCACAAGTTCGTGTGTAAAGTGTGCGGCTCATGCTTCTCCAAGTCGACCAGCTACTTGACGCACCTGCGGCTGCGGCATCCATCTGAACACAGCTGCGGCGAGTGCGGGGAGCGGTTCATCAGTCGCAGCGGGCTCAGCATGCACGCGAAGAAGGCGCACAAATATCAGAAGTCCAGCTTGATAGCTCAGTACAAATGTGCGCTGTGCCAATTCAAGTTTAGGAGCTTCGACGCGCTAAACAAACATACAACGTACTCTGAAAATGGAATCTGTGATAGTAACCTAAGTCCATGCCATCAATGCGGTGACAGCTTCTCGAGTCCAGAGTTGCTTAAAGACCATCAGAAGACCCACCACAGTACTGTAGAAGTGAGATGCGATGAGTGCGGGCGCACGTTCGCACACGAGCGCTCGTTCTCGGTGCACTACCAGCGCGTGCACCTCGGCATCAAAGAGAAATACAAAACCGCCGACGGGAGGAGACAAGCCGCCGTCGTCTGCGAGATTTGCGGGAAGAAATGCATTTCCAAAGCGACCCTGGTGTACCATCAGAGAACACACACTGGAGAGAAGCCGTTTCAGTGTGCTGAATGCCCGAAGAGATTCAGCGTGTTTCAGCGACTGACGATTCACATCAGAACGCACACTGGGGAGAGGCCATTTAAATGCCAGCACTGTCCTAAAGCATTCAAACATAAGGCTGCTCTCAATAGACACGACCGGGTGCACTCGGGGGCGAAGCCCTACACCTGCACGCACTGCGGCAAGTCCTTCTCGCAGTCCAACTCAATGAAACTGCATGTCCGGACTGTGCATCTGAAAATACCGGCGCCGTACAAGAGTCGCAGGAATAATAAAAATAATGAGTGA
Protein Sequence: MEEPFACRVCLVTDVTLYYMHDNGLKTAYENLTGVVMMPDSLPQYLCAYCSALVRKCVAFKERCLRSQELLKYTVMHQQVLTTNYIRTIDRASHQIILPYTIVSTHKETTDGDTIKEENLFDSNLIKTEDNEVSDEEPLSRKVEKKKKLKNQVEIKQEFDEIDFIDNQIDSTDNFDDTTVGENVIYDRSTEKEIDMMVLTKQQQLDEVLARKDSYNYQNSFYKCDKCFKGFVTDVTYKNHMIRHDSSSGPEVCEICQTRWVDARSLRAHVATSHQRRYSCRLCDHTCKSSHKAKEHQKWHSGHKFVCKVCGSCFSKSTSYLTHLRLRHPSEHSCGECGERFISRSGLSMHAKKAHKYQKSSLIAQYKCALCQFKFRSFDALNKHTTYSENGICDSNLSPCHQCGDSFSSPELLKDHQKTHHSTVEVRCDECGRTFAHERSFSVHYQRVHLGIKEKYKTADGRRQAAVVCEICGKKCISKATLVYHQRTHTGEKPFQCAECPKRFSVFQRLTIHIRTHTGERPFKCQHCPKAFKHKAALNRHDRVHSGAKPYTCTHCGKSFSQSNSMKLHVRTVHLKIPAPYKSRRNNKNNE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -