Druf014616.1
Basic Information
- Insect
- Drymonia ruficornis
- Gene Symbol
- ZIPIC
- Assembly
- GCA_947859195.1
- Location
- OX401919.1:12542292-12543764[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0012 0.071 13.7 0.5 2 23 171 192 170 192 0.97 2 11 0.004 0.24 12.0 3.2 1 23 198 220 198 221 0.94 3 11 6.7e-06 0.0004 20.7 0.4 1 23 228 250 228 250 0.98 4 11 5.5e-07 3.3e-05 24.2 2.3 1 23 256 278 256 278 0.98 5 11 5.1e-06 0.00031 21.1 3.9 1 23 284 306 284 306 0.95 6 11 2.9e-06 0.00017 21.9 1.6 1 23 312 334 312 334 0.99 7 11 1e-06 6.1e-05 23.3 0.5 3 23 342 363 341 363 0.97 8 11 0.067 4 8.2 0.2 3 23 370 387 368 387 0.76 9 11 0.0005 0.03 14.8 0.4 1 23 393 416 393 416 0.95 10 11 0.0023 0.14 12.8 0.5 1 23 422 447 422 447 0.95 11 11 0.00065 0.039 14.5 5.5 1 23 453 476 453 476 0.97
Sequence Information
- Coding Sequence
- ATGGATTCAAAGCTGTGTCGAGTTTGTCTCAACAAGTCGGCCTCATTGTCTGTATTCGATAAGCAAGATGATGATATCCAGTACAGTACAAAAATAATGAGGATCGTCAACATAGCAGTGGTGGAAGGCGACGGACTACCGGATGCTATCTGTAATAGCTGCGCAGAGGAACTCTCTACATCGTACGAGTTCGTGAACAAGTGCGAAGCGACCGACCAAGCCTTACGCTGCGCTGCCATCTCTGACCTGAAAGCAGAAGCCTCCGCAACAGAAATGCCGATCAGAATAGACGATATAAAACAGGAACTAAAAATCGACGATGAACTCCTAAAACAGGAACTAAAACCGGATGATGAACTCCATTTTCTACCGGAAATGTTCGATGATTTCCTTCCAGACTCTTCTGACAATTACAAAGTCAGTAAAAAATTAAAGAAGAAGTATAAAAAGCGTGATAATGTAGTAGAGAAGATTGATAGAAGAAAACTAAGACCCAAAAGTGGTCCTGTACCATGTGAGGTATGTGGGTTGATGTCCACTTGCAGATCAGCACTGGAGACCCACATGAGGACGCACACTGGAGAGAAACCATTTGCTTGTCACTCGTGCAACGCACAATTCAATCTAAAAGGCACACTCAATAGACACATTTTAAATCACCACACAGAGAGGGAAAGGAAATTCGTCTGTGAAACTTGTGGCAGCAGCTTCTATACAAAAGATAATATTAAAATACATATTCGAGTGCACACTGGTGAGAAGCCATACTCTTGTGTGTACTGCGGCAAGACCTTCCGGCAGACTACTTCCCTGATACGCCACAAACGCATGCACACCGGGGAAGCACCTTATTCATGCCAGATATGCTCTAAAACATTCAAAGACAAGAGTCATTTGTTGAGGCATAGTTATGTGCATTCGGATGAAAAGAATTTCACGTGTGATCTATGCAGCAAGTCTGTCAAATCAAGGAACGCACTTAAAACTCATATGCGAACACATTCCTGTGAGAAACATAATATTTGCAACTATTGTGGCATGACTTTCTCCCTGAAAGGCAACCTCCAAGTGCACATACGTAGGAAACATTCTGAAAGGTCCGGGGAGTGCAGTATTTGTCTGAAAACATTTCCCGACTTAGAAGTACATCTGCGGAAGCACACGGGAGAGAAGCCTTTTGTTTGCAAGTTATGCAACCAGAGCTTTGGGCTGCAGGGGAGCCTGGCCAACCACATCAACTTCAAGCACAAGAACACGAGCAAATTTAAGTGTTCTATAGGAGAGTGTACTAAGACATTTCCTTCAGCGAGTATGTTGGAGTTCCATCTGCTGAAATATCATACAAATCATACTCCATATATCTGCCAACACTGCTCGAGGGGCTTCTTCCGGAGTTGCGATCTCACCAAGCATCTTAAAATTAGTCACATGGATTCGGAAATTAAAATCCCTGTCAAGGATCTCATACAATAA
- Protein Sequence
- MDSKLCRVCLNKSASLSVFDKQDDDIQYSTKIMRIVNIAVVEGDGLPDAICNSCAEELSTSYEFVNKCEATDQALRCAAISDLKAEASATEMPIRIDDIKQELKIDDELLKQELKPDDELHFLPEMFDDFLPDSSDNYKVSKKLKKKYKKRDNVVEKIDRRKLRPKSGPVPCEVCGLMSTCRSALETHMRTHTGEKPFACHSCNAQFNLKGTLNRHILNHHTERERKFVCETCGSSFYTKDNIKIHIRVHTGEKPYSCVYCGKTFRQTTSLIRHKRMHTGEAPYSCQICSKTFKDKSHLLRHSYVHSDEKNFTCDLCSKSVKSRNALKTHMRTHSCEKHNICNYCGMTFSLKGNLQVHIRRKHSERSGECSICLKTFPDLEVHLRKHTGEKPFVCKLCNQSFGLQGSLANHINFKHKNTSKFKCSIGECTKTFPSASMLEFHLLKYHTNHTPYICQHCSRGFFRSCDLTKHLKISHMDSEIKIPVKDLIQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01179693;
- 90% Identity
- -
- 80% Identity
- -