Basic Information

Insect: Drusilla canaliculata
Gene Symbol: Zfhx3
Assembly: GCA_027574885.2
Location: JAODGA020003938.1:4501-11651[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.3 40 5.5 0.3 2 23 180 202 179 202 0.94

2 18 0.00015 0.02 15.9 1.8 2 23 352 374 351 374 0.95

3 18 3.7e-05 0.005 17.8 0.7 1 23 406 430 406 430 0.92

4 18 0.0055 0.73 11.0 0.4 1 22 474 495 474 498 0.91

5 18 7.3 9.7e+02 1.2 4.2 1 20 648 667 648 672 0.89

6 18 3.3 4.4e+02 2.3 0.3 2 20 705 723 704 728 0.91

7 18 6.2 8.4e+02 1.4 1.4 1 23 753 777 753 777 0.90

8 18 1.3 1.8e+02 3.5 0.1 1 21 872 892 872 895 0.78

9 18 0.00013 0.017 16.1 0.2 1 23 906 929 906 929 0.96

10 18 0.23 31 5.9 1.8 2 22 1020 1040 1020 1043 0.90

11 18 0.11 14 6.9 0.4 1 23 1055 1080 1055 1080 0.88

12 18 0.0025 0.34 12.1 1.6 1 23 1098 1120 1098 1120 0.97

13 18 0.00055 0.074 14.1 0.7 2 23 1127 1149 1126 1149 0.94

14 18 0.00071 0.094 13.8 3.2 1 23 1257 1281 1257 1281 0.92

15 18 0.0043 0.58 11.3 0.6 1 22 1301 1322 1301 1325 0.89

16 18 0.00087 0.12 13.5 0.2 1 23 1376 1400 1376 1400 0.93

17 18 0.0044 0.59 11.3 0.0 3 21 1479 1497 1478 1498 0.95

18 18 0.26 34 5.7 2.5 2 19 1639 1656 1638 1661 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.3	40	5.5	0.3	2	23	180	202	179	202	0.94
2	18	0.00015	0.02	15.9	1.8	2	23	352	374	351	374	0.95
3	18	3.7e-05	0.005	17.8	0.7	1	23	406	430	406	430	0.92
4	18	0.0055	0.73	11.0	0.4	1	22	474	495	474	498	0.91
5	18	7.3	9.7e+02	1.2	4.2	1	20	648	667	648	672	0.89
6	18	3.3	4.4e+02	2.3	0.3	2	20	705	723	704	728	0.91
7	18	6.2	8.4e+02	1.4	1.4	1	23	753	777	753	777	0.90
8	18	1.3	1.8e+02	3.5	0.1	1	21	872	892	872	895	0.78
9	18	0.00013	0.017	16.1	0.2	1	23	906	929	906	929	0.96
10	18	0.23	31	5.9	1.8	2	22	1020	1040	1020	1043	0.90
11	18	0.11	14	6.9	0.4	1	23	1055	1080	1055	1080	0.88
12	18	0.0025	0.34	12.1	1.6	1	23	1098	1120	1098	1120	0.97
13	18	0.00055	0.074	14.1	0.7	2	23	1127	1149	1126	1149	0.94
14	18	0.00071	0.094	13.8	3.2	1	23	1257	1281	1257	1281	0.92
15	18	0.0043	0.58	11.3	0.6	1	22	1301	1322	1301	1325	0.89
16	18	0.00087	0.12	13.5	0.2	1	23	1376	1400	1376	1400	0.93
17	18	0.0044	0.59	11.3	0.0	3	21	1479	1497	1478	1498	0.95
18	18	0.26	34	5.7	2.5	2	19	1639	1656	1638	1661	0.90

Sequence Information

Coding Sequence: ATGCCCACCCTGTCCGCGGCGCCTGAGCTCAGTTCCGGCGGCCGCAGCGAGCGGCAACAACCACCACCACAGCTACCGCCCCCATCGCCGCATCAGCTCGCTGCTGCCAGCCAGCAGCAGCATCTGCAGCAGGCGCATCGCGCGATGAGCCCCGAGCAGGAAGCGAGCCCGCCGCCAGCGGCGCCCGGCGCttcgccaccgccaccgcccaCGACGCACATACCCACCTCGCCGGCGATGTCGCTGCAGGACAACAACACGTCCGACGTGGAGCAGTTCGCCGGCAAGATCGTCTACAACCCCGACGGCTCGGCGTACATCATCGAGGACTCAGAGAGCGAGAGCGAgtcgacgccgccgccgtcgtcgcaGGCGGAGGTTGTGCCACCGCTGCAGGCTGTGTACGTATCGCGGCTGCTGCGGCAGGCgcgcaccgccaccgccgccgagcaACCGGCGGTGCACAGCTATCGGGTGATTGCGTTGCGCGACGCGCGTCCCCCGCGGCCGCAGTCGGTGCCGGTGAAACCCATCCTCATGTGCTTCGTGTGCAAGCTGAGCTTCGGCTTTGCGCGCTCGTTCGCGAATCACGCGCAATCCGAGCACGGTGTCGCGCTGAAAGACAACGAACGTGAGGTGCTCGCCGCCGACTGCTCGGCGATCCTGCAGTGTGTCGGCGCTGACAAACGGCCGATGGTCTCATTGCTGGAACCTCTCGGCACACCTACACCACCACCGTCGGCGGCGTCCGAAATCACCGGCGTCAACTCTGCGGTGCCCGTTTCAATAAACCCACCCACGAGTCTGCCGCAATCCGAGACGCCTCCGACGAGCACATCGTCAGCGCGCAACACACCCGGCAAGTCGCCCTCGCCGCCGTTCGCGCAACCGCCACAGTTCCTCACCGGCACCACAATCGGCGTGTGTCCCGAGCATCTGCAGGGGCGGCCGTCGGGCGCCGACTGCGCACGCTGCGAGATGATCCTCGCGTCGGGCCGCCTCGGCCCCGCTGGTCTCGGCAACGTGCACAGCCGCAACTCGTGCAAGACGCTCAAATGCCCCAAGTGCAATTGGCACTACAAGTACCAGGAGACGCTCGAGATTCACATGAAGGAGAAGCACCCGGAGGCGGAGACCAGCTGCATCTACTGCATCGCCGGCCAACCGCATCCGCGGCTCGCACGTGGCGAGACGTACACGTGCGGCTACAAGCCGTACCGCTGCGAGGTGTGCAACTACTCGACGACAACCAAAGGCAACCTCAGCATTCACATGCAGTCTGACAAGCATTTGAACAACATGCAGGAGCTGCAGAACGGCGGCGCGCCGAGCGTGGAGGCGCGACAAGCGTCGCCGAAAGCGCCGCCGTTGCACCACACGCCCGTGAGCGCGGGCGGCGGTCACAAACCAAAGCCCAGCTTCCGCTGCGACGTCTGCAACTACGAGACGAACGTGGCGCGGAATCTGCGCATCCATATGACCTCCGAGAAGCACACGCATAACATGCTCGTCCTGCAGCAGAACGTCAAACACATGCAGACGTTATCAGCGCTGCAGCATcatcagcagcagcaacacCCCGCTGCGCAACCGCACATGGAGAGCCTTTACGGCATGTACCCTGGCCTAGGCGATAAACCGGAAGCGGCGCTCGCCGACATGGCCTACAATCAAGCGCTGCTCATTCAGATGATGACCGGCGGTCAACTGCCCGGTCACGGTGCGCCCGGCGCAGATATGAGTCAGCACGCCGACATGGGTCTCAATCCGGAGACGATGGAACCGCCGCCGGAGCCGGCGGATCCCGATCCGGAGCGCACCTACCACTGCTGCGTATGCAACTGCTTCGCAACGGATAGCCTCGAAGACCTGGGGCGCCATCTCGCGCAGGATAGGACGCGGTTGCGCGAGCAGGAGATCCTCGCCGTCGTCGCCGGCCATTACGTGTGCAAGCTGTGCACGTACAAGACGAACCTCAAGGCCAACTTCCAGCTGCACTGCAAGACTGACAAGCACCTCCAGCGGCTGCAGCACGTCAACCACGTGAAGGAGGGCGGGCCGCGCAACGAGTGGAAGCTCAAGTACGCGTCGGCGCCGGGCGGCGTGCAGATACGCTGCAACGCGTGCGACTACTACACGAACTCGGCGCACAAGTTGCAGCTGCACGCCGCCGGCGGGCGGCATGAGGCGGGCGTCGCACTGCTACGCCACGTGGTCGAGCGCTGCGCCACGTTACGCGCCGACCAGCCACGTGTGTTCCACTGCTCGTTGTGCTCGTTTTCCGCCACCAATCGCCTGCCGCTGCTGCAGCACGTGCGCTCGCTGAAGCACTTGCATCTCGAGCAGTTGCACCAACTGCAGCGGCGCGCCGAAGGCAAGGACACCGCCCCCGATATTGGCGAAGTGTTTCACGTTGTACCTGGGCCTGTCGATCAATCTATGACGGAACGAAGAGATAGCGTCAATTCGGAGCAATCGAATCAAGCCGAGAGCAACCATCAGCTCGGCGGCAAGGAATTCAAGATGGAGCCTTGCGACGACGAGATGTCTGTcgttggcggtggcggtggcggcagtggcggtggtggtgatgCGGCGAGTGGCGGCGCACCGCACGTGTGCCCGTATTGCGACTACGCGAGCGACTCGGAGATGCGCATCCAGGCGCACGTGCTCGCTCAGCACGGTACGAATCACAGTTCCTCGGAACCGAGCTTTCAATGCCCCCTGTGTCAGGATGCGTTCAAAGATCGCTCCAGCTTAGAGCGGCACGTGATGCAGATCCACTCGGTGAACAGCGAGGGCCTGCAGCGGCTGCTGATGCTCGTCGATCAGAGCCATTGGCTGAATCGTTCGCCGAGCCATACGAACAACgccggtggcggtggtgcTGGCGGCGCTGGCCAGCAGCAGCTCACGTCGCCTACGTCGGTGTCTTCCAAGGACAGCAAGCACACGCCGGAGAAGGCGTCCACGCCAAATCATGCAATCGACCTCGAGAATGATCTCATGTCGCCGGCGCACAGCGACGACGCCACTGACGTTGCCGAGTTTGAGCGGTGCGCGACGTGCatgaaaagtttcaaaaacattGACGAATTATGCTATCATCAGAATGAGACCGGCCACCTGGAGATTAAGCAAACGCCAAGTGGGCCCGGTTATGCGTGCTGGAAGAAGGGTTGCAATCAGTTCTTCCCCACCGCGCAAACGCTGCAGATGCACTTCAAGGACGTACACGCCAAGAACTCGGTGTCGCAGATGAGCGTCTCCGAGAAGCATGTGTACAAATACCGATGCAATCAATGCTCGCTGGCGTTCAAAACCCTCGAGAAGCTGCAACTCCACTCGCAGTATCATCTCATTCGCGATGCGACCAAATGCGTTCTGTGCGGTCGCAGCTTCCGGTCGCTGGTCGCGCTGCACAAGCACGTTGAGAGCGTGCACTCGGAGCTCACCGACGACGAGCTGAATGCGTACAAACAAAGTCTGATGAACAATCCGCTGCTATTGGCCGGTCTCCAGGGACAAGTGCTTGACAGCTCTACGAATGATATTCTCAAGAAGGAGTCGCTGCGCTCGGATGATGTTGAGTCGGTTGCAGATGGCGACGACAGCAAGGAGTTGTCCACGAGTCACGACGACAGTAATGCCAACGACGGCGAAAACTCGAACGATAGCATTATCTACAAAGATCAGCAGTTCCTAGAAGATTACCTGAACAGTCAGGCGATCGCCGAGGACAGCTACAATGACCCAAACAGAAAGTACAAGTGTCACCGGTGTAAGGTGGCGTTCACGCGGCAAAACTACCTCACCGCCCACAACAAAACCCTTCTGCACCGCAAAGGCGAGAAGCTCAGCTACCCTATGGAGAAGTATCTCGACCCGAATAGACCGTACAAATGCGACGTGTGCAAGGAGAGCTTTACGCAAAAGAACATTCTTCTTGTGCACTATAATTCGGTGAGTCATTTGCATAAGCTGAAGCGCGCAATGcaagaacaacaaaacaacaacaataacaatccGCCTGTGTCGCCGGTGATTGGTGGGCAAGCGCCCGCTCAAGCGCCGGGCACACCTAAGAGCACCTCCAGTAATGAAGATGACGACAAAAAGCGCTACCGTTGTAATATCTGCAAAGTGGCGTACACCCAGGGCTCGACCCTGGATATTCACATGCGCTCGGTGCTGCATCAGACGCGTGCCAGCAAGCTGCAAGATTTGGCCATGGCCGGCCAGATCGACCTCTCAAAGCCGCTCATCGAGCAGCCCGACGTCGTCGTGCAGTCTCCCAGCCAGCAGCAGTCGCAGCACGCGAGCCCAACGCCCGGCGGAGGGGAGAAGACATCCCCCACCCCACCGGCCGCGTCGCCCGTGCCCTCCTCGGCAGGTAACAGCACGGCAGGTAGCCAAGGGATGATGCCGGCGTGCCCCAAGTGCGGTGCGCTCTTCAGCTCGGCGGATCAGTTGAGCGTTCACCAGCAGCTGTATTGCATGTTCGCCGCGCCGAACATGGCCATCTTCCAAGCGCACGAACCGGGCACGGCGAAGAGTCCGCCGCCCGCGACGgtcgccgctgctgctgctggcgaCCAGCAAGCCAACGACGCCGCCAATCGACTCAGCGTACCAAAGCGCATCAACTCGCAGATGCAGAAGCACTTGCTCGAGAGCTACGGTTTTGACGTGGTGATGCATTACAACGAAAGCCAACACCGCCGACgacagcagcaacaacaacaaatgcaacaacaacagcaacacgCGGCAGACGACAAGCGGTCGACCACGGCCTCATCGCCAGCTACCGCCGCCattgcagccgccgccgccgccgacgattCCGAAGCCACATCGCGGCCAGCCGAGGACGACAATGAAAACAACTTACCCGAAGTAAGTACATCCACGTGCCAACATTGCAATAAAGAGTTCTCTAGTGTGTGGGTGTTAAAGTCTCACTGTGAAGAAGTACATAAAGATTTAGTGCCGCTAGAATTCTTAGAAAAGTATGCTCAACAGTTTAAGAATGAATACGAAAAGAAAACGGTGGTGGTGACTGCGGCGACCTCGTCGACGCTCAATAGCAACCCGCGCGTCAGCTCCTCGCCGacttcggcggcggcgatggcggcagGCGGTGGtaatggtggtggtggcggcagtgaGCCGACCGACAAGGACGACGAGTCCAAGGAGGCGCTGCACGCCAAACTGAATTTGCATGCGACGCCCGAGGCGGCGCACTCGACGGCGCCGTCGACGCCGACGTCGTCCTCGACGACGCCGACGGCGAGCAGCACCGACTCGCTGCCGGCAAACATACAAGCGATGATCGCGCAGACGATGGCTCAGAACCCCATGGCATTTGCGCAGCAGGTCAGCGAGATGCAGGCGGCGCTCAACGTCATGCAGCTGCAGCAGCAGCTCAACTTCAATCCGATGATGCAGATGATGGGCATGGGCCTGCCGCTCGGCCTCAACGCGCTCGCCGCGATGAACCTCCAGCCGCCGCTCGTGCCGCTGAtgatgccgccgccgccgttcgACGCCATGCAGCAGTTTGCGCCGCAGGAG
Protein Sequence: MPTLSAAPELSSGGRSERQQPPPQLPPPSPHQLAAASQQQHLQQAHRAMSPEQEASPPPAAPGASPPPPPTTHIPTSPAMSLQDNNTSDVEQFAGKIVYNPDGSAYIIEDSESESESTPPPSSQAEVVPPLQAVYVSRLLRQARTATAAEQPAVHSYRVIALRDARPPRPQSVPVKPILMCFVCKLSFGFARSFANHAQSEHGVALKDNEREVLAADCSAILQCVGADKRPMVSLLEPLGTPTPPPSAASEITGVNSAVPVSINPPTSLPQSETPPTSTSSARNTPGKSPSPPFAQPPQFLTGTTIGVCPEHLQGRPSGADCARCEMILASGRLGPAGLGNVHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPEAETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQNGGAPSVEARQASPKAPPLHHTPVSAGGGHKPKPSFRCDVCNYETNVARNLRIHMTSEKHTHNMLVLQQNVKHMQTLSALQHHQQQQHPAAQPHMESLYGMYPGLGDKPEAALADMAYNQALLIQMMTGGQLPGHGAPGADMSQHADMGLNPETMEPPPEPADPDPERTYHCCVCNCFATDSLEDLGRHLAQDRTRLREQEILAVVAGHYVCKLCTYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGPRNEWKLKYASAPGGVQIRCNACDYYTNSAHKLQLHAAGGRHEAGVALLRHVVERCATLRADQPRVFHCSLCSFSATNRLPLLQHVRSLKHLHLEQLHQLQRRAEGKDTAPDIGEVFHVVPGPVDQSMTERRDSVNSEQSNQAESNHQLGGKEFKMEPCDDEMSVVGGGGGGSGGGGDAASGGAPHVCPYCDYASDSEMRIQAHVLAQHGTNHSSSEPSFQCPLCQDAFKDRSSLERHVMQIHSVNSEGLQRLLMLVDQSHWLNRSPSHTNNAGGGGAGGAGQQQLTSPTSVSSKDSKHTPEKASTPNHAIDLENDLMSPAHSDDATDVAEFERCATCMKSFKNIDELCYHQNETGHLEIKQTPSGPGYACWKKGCNQFFPTAQTLQMHFKDVHAKNSVSQMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHLIRDATKCVLCGRSFRSLVALHKHVESVHSELTDDELNAYKQSLMNNPLLLAGLQGQVLDSSTNDILKKESLRSDDVESVADGDDSKELSTSHDDSNANDGENSNDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQNYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNNNPPVSPVIGGQAPAQAPGTPKSTSSNEDDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMAGQIDLSKPLIEQPDVVVQSPSQQQSQHASPTPGGGEKTSPTPPAASPVPSSAGNSTAGSQGMMPACPKCGALFSSADQLSVHQQLYCMFAAPNMAIFQAHEPGTAKSPPPATVAAAAAGDQQANDAANRLSVPKRINSQMQKHLLESYGFDVVMHYNESQHRRRQQQQQQMQQQQQHAADDKRSTTASSPATAAIAAAAAADDSEATSRPAEDDNENNLPEVSTSTCQHCNKEFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKNEYEKKTVVVTAATSSTLNSNPRVSSSPTSAAAMAAGGGNGGGGGSEPTDKDDESKEALHAKLNLHATPEAAHSTAPSTPTSSSTTPTASSTDSLPANIQAMIAQTMAQNPMAFAQQVSEMQAALNVMQLQQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPFDAMQQFAPQE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -