Dwil007525.1
Basic Information
- Insect
- Drosophila willistoni
- Gene Symbol
- -
- Assembly
- GCA_018902025.1
- Location
- CM032166.1:12459596-12463561[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 3.3e-05 0.0027 18.2 0.1 1 23 171 194 171 194 0.96 2 13 0.0047 0.38 11.4 3.2 2 23 243 265 239 265 0.89 3 13 0.0072 0.59 10.8 0.8 1 23 368 391 368 391 0.93 4 13 0.056 4.6 8.0 6.6 2 23 440 461 439 462 0.94 5 13 0.004 0.32 11.7 0.7 1 23 518 541 518 541 0.88 6 13 6.5 5.3e+02 1.5 0.1 2 14 560 572 559 584 0.83 7 13 0.00079 0.065 13.9 3.5 2 23 592 614 592 614 0.96 8 13 0.017 1.4 9.7 0.8 1 23 696 719 696 719 0.97 9 13 0.00071 0.058 14.0 0.3 1 23 770 793 770 793 0.93 10 13 0.0011 0.089 13.4 2.2 2 23 843 865 842 865 0.97 11 13 0.0075 0.62 10.8 1.7 1 23 956 979 956 979 0.92 12 13 0.05 4.1 8.2 1.5 1 21 1031 1051 1031 1052 0.95 13 13 7.1 5.8e+02 1.4 0.6 1 12 1142 1153 1142 1166 0.66
Sequence Information
- Coding Sequence
- ATGGAAGGCATGGACCTGTGGACGTCAATGTTCTCCAATGATTTTGAGGAGGGTGAGGAGAGCGAACAATATGGCAATGGAACGGGAACGGGTGTCAAGCCATCGGCGGACACAGACGATATAATGGCCGAGGCTTACGATGGCGATGAGGGCGTTGATGATGATGATGACCTTATGGAGATGGAGGATAATGGCGAAATGGAGGCCACTGAGGAGGAAGGTAGAAATGGCAAGCAAAAGGGACCTGAACCTGATGATGATGCCATATTTGATTTTGAACTTGAACCGATTGTAAGCATAGCAGAGCATCCAACCACTCCACTGGGACCAGCTGGCCCTACTTCAGCTTCAGTGCGTCCGATGCATCGAAATTCATTGCCAGCAGGTGGTTCGATTTCCGGCCGGCCTAAAGAAATGCGGTTATCTGGCGTTCAAATGCGCCCAACCACCTCCCAAATAAATGCCACCGACGAACATGGTGTTCCCATTAACTACGAGCTGGGCGTAATCTACATTTGCCCCGCATGTGGAGCGGAATTTCGGCAACAGGACCAATGGAAGCGTCATATGAACCAAATGCATCAATTCAACACACGACGAGGTCTCAATTTTGTGGCCATGGATAAGCTATATCAGCGCTGTCTCGAATGCAACAAGCGCATTGCTATGCACAGTCGTGAGAATCTTCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACAAAGTGCTACCTATGCAAAAGGGAGTACAAATATAGACAAGATTTGATGGTTCACCTGCGAATGGTGCATTGTGAGGAGATAGTGAACATGATGCGGGGTGGTTACTCTGCGGCGGGACGTAAGACACGTGTAAGAGAGCCACGTACTGAGCGAAAAGAGTTCTGTCCCGAAGATGACGATGCCATTGAAGTGAGGAATGAAGTGCTCGAACCTGATCTGGATGACTCTAGTTTCGTTGTATCGTCCACTTCATTAGTGGAAGAAGAGCAACCACAAAACTCAACTCCTCAGCCTTTGTCTGCCAAGCGAAAGCGCAGTCATCCTTCGGGAAATGGAAGTGGGGGCGCCACCGAACTGTGTGAGGATTATATACATTATATGTGTCCCGATTGTGGGACAGAGTGCGAAAATCATGCCCAATGGAGCCAGCACATTGAGTTTGTGCATGATTATGTTAGTCGTCGGGGACTCAACTTTAGGAGCGTCGACATGCAGATGCAATGCTTGGAATGCAAACAGATTGTTACTCCCAACACGATTAAAACTCTGAGAGCTCACAAATTCAGCCATCTTCCGCAGCCCGAGTGGCTGCGTTGCAAGCTTTGCTACAAGAGCTATACGGAGCACCATGAGTTGGTGACTCATTTATTGAAACATCACAATCTGGAGACCCTGATACCAGCCGATGGACAAGATGAACAATTGCTGTGTGCACCAGATGACGACGGAGGAGATGGCGGTGAGATGATCTTCGATGATGCCGATGAGGTCCGTAGACGTGGTGGAAGGATAAGTAGCGATGATATCTATGAGCCGCACATCGATTACCTTTGTCCGCAGTGCGGCAAAGAGTTCATGGAGAAAAAACATTGGCGTACCCATGTGGTTCAAGTGCACGGCATGAATGACATTGCAAAGCTGAACTTTGAGATTATATCGGAACGGCAGTTGAAGTGCACGGAATGCGAGAAGATCATCACGAATGCCTATGGCATACAGAATGCCCAACAGCATAGGATAACGCATTTACCATTTAAAGCCTATGCCAGGTGTCGCAAGTGCCACAAGACCTATACGGATCGCAAGGGATTGGTTAAACATTTGGCCACATATCATCGTGTGGGCTGGGAGACTGGTCGAAAGTCCGGCGTAAGTGGTGATGCTCCTCTGGCGCCAAAGCAACCGCGTAAACAAATTGTGACCGTGGCTAATGAGACATATGAGATTATATATTTAGATGAGGAGCCAAGCAACGTTGAGGAGAATGATTTTGGTGAGCAAATGCAGGCGGATGACGATGAGTATGCGCCTGCTCCACCTCCTCCGCCAGTACCGCCACCTAATCCTCCTCCCACTCGCTTCAAGTGCTCGGATTGTGGTTCAATACACACTACTCAAATGGCTCTCAAGATGCACATTAGGGAGGAGCATGGCTTAAGGGAATCCAAAAATATTTCAAAGAAAAACACCGAGTCTAAGGATGAAAAGAAAAGGAGCAGTGCATCTTCAGCTTCTTCCACACACACTCCAAACGCCACCTCCATGCGTTCTCCAGGCACCACAATTGAGCAGAATTACATCTTCCTATGCCCATCTTGCGGTGAGGAGTACAAGACGCAATTCGAGTGGCGTCGTCACATCAACGAATCCCACAATTTTGATAAACGGGAGTACTTGAATATGCGGCAATTGGACAAATATCGATATCAGTGTACCCAGTGCAAGGATATCGTCTGCAACTCGAAATTGAAGGGACTTCAAGACCATCACTTTCGGCATTTGCCCTACCGTTTGTATCTCAAGTGCTTAGTCTGTGGCACTTGCTACAACCACAAGCCGAATATAGCAGCTCATCTCCGGACACGTCATAATATTTTTGAGCGGGAAACGCCTTGGCGAGAGCAACGCAATAAACCGCAATATGCATACGTTCAATCAAAGGATTCGGCCGATAAGGAAAAAAGAAGCCAGCGGGCAGAGTCACCAGTTGCTTCTTCATCGTCGTCATCGGTTTCGGCTATGGGGAGCAGCCGCACGTTGAAGCCCCAACCAGGCGGATTGCCGACGCGGCCCGCCGGTCTAAACACGCTGGAGGATAGCATTTCGTATCACAATGCTGTCGATCTGGATTTCATCACGTACTACTGCCCAAAATGCAATCAGAACTTCGATTCGCATGCATTCTGGCGCAAACACATTGTGGAGCAGCATAATTTCAATTGCCGTGAGGGGCTTAACTTTCGACAGATTGACAACCATCATTACCTATGCCTGGAATGTTATAAGCGGGTTACGGTCACCCACACTAAGGGAGCCATTGGCCAGCTTCAGTCGCACAAATTCCGTCATCTGCCGTATCGCTCTTTCAAGTGCTTGACCTGCAATGGAGAGTTTGTGCGCAAACAAATGTTCTTTAAGCACTTGAACAGGGATACCAATAGATGCGATAATCGACCCAGCGGACCAGATGCCCCAGTCATCGATGACGATGATCAGGAGGGGGCACCTGGCGCAGGTGGTGAAGTGGTGACTGTGGAAGATGAGGAAGTAGATCCTTCTGCCTATCGTTTAATGTGCCCGCAATGTGGCGACAATATCGACACAAGCAGCAAAGCCGTTTGGCGGGAGCACATTAACATCTACCATGGCCTGGGCAAGAAGGAACTCCTACATATGCGAAAAATTGGCGACGATCTCTATCGTTGTTATGACTGCGATGAGGAGCTGCAGACGAAGAAGCTTCGTGTGCTTCAGCAGCATCGTTTCCGACATCTGCCTTATGCCGCGTACATACGTTGCTTGCTCTGCGAAAATCCAGAGGGCGATGATGCCATTGATGCTGCAGCCGGCCTGCATAGTATGCGAGAATTGCAGCAGCATATACGGGAACATCATCCGGCCATCGAGGACAACGATGAGCAAATGCAGAATGTGCGTCAACAGGCAGCCGAAGAGGAGGGTGACGAGGACAGTCATTTGGAAACCGAGACCGCGGCCAGTACGGGTTCAGGTAATGGTCCATACATGCCGCTGCCACCGCATTTGTTGGATGATGCTGATGATTTTGAGGAACAATATTTACTTGGATAG
- Protein Sequence
- MEGMDLWTSMFSNDFEEGEESEQYGNGTGTGVKPSADTDDIMAEAYDGDEGVDDDDDLMEMEDNGEMEATEEEGRNGKQKGPEPDDDAIFDFELEPIVSIAEHPTTPLGPAGPTSASVRPMHRNSLPAGGSISGRPKEMRLSGVQMRPTTSQINATDEHGVPINYELGVIYICPACGAEFRQQDQWKRHMNQMHQFNTRRGLNFVAMDKLYQRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYLCKREYKYRQDLMVHLRMVHCEEIVNMMRGGYSAAGRKTRVREPRTERKEFCPEDDDAIEVRNEVLEPDLDDSSFVVSSTSLVEEEQPQNSTPQPLSAKRKRSHPSGNGSGGATELCEDYIHYMCPDCGTECENHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKQIVTPNTIKTLRAHKFSHLPQPEWLRCKLCYKSYTEHHELVTHLLKHHNLETLIPADGQDEQLLCAPDDDGGDGGEMIFDDADEVRRRGGRISSDDIYEPHIDYLCPQCGKEFMEKKHWRTHVVQVHGMNDIAKLNFEIISERQLKCTECEKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKTYTDRKGLVKHLATYHRVGWETGRKSGVSGDAPLAPKQPRKQIVTVANETYEIIYLDEEPSNVEENDFGEQMQADDDEYAPAPPPPPVPPPNPPPTRFKCSDCGSIHTTQMALKMHIREEHGLRESKNISKKNTESKDEKKRSSASSASSTHTPNATSMRSPGTTIEQNYIFLCPSCGEEYKTQFEWRRHINESHNFDKREYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERETPWREQRNKPQYAYVQSKDSADKEKRSQRAESPVASSSSSSVSAMGSSRTLKPQPGGLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNQNFDSHAFWRKHIVEQHNFNCREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNRPSGPDAPVIDDDDQEGAPGAGGEVVTVEDEEVDPSAYRLMCPQCGDNIDTSSKAVWREHINIYHGLGKKELLHMRKIGDDLYRCYDCDEELQTKKLRVLQQHRFRHLPYAAYIRCLLCENPEGDDAIDAAAGLHSMRELQQHIREHHPAIEDNDEQMQNVRQQAAEEEGDEDSHLETETAASTGSGNGPYMPLPPHLLDDADDFEEQYLLG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00503590;
- 90% Identity
- -
- 80% Identity
- -