Basic Information

Insect: Drosophila willistoni
Gene Symbol: -
Assembly: GCA_018902025.1
Location: JAFEWB010000715.1:5583990-5586476[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.021 1.7 9.4 1.8 2 23 345 367 344 367 0.96

2 9 0.062 5 7.9 0.5 3 23 425 446 423 446 0.94

3 9 8.3e-06 0.00067 20.1 0.6 1 21 460 480 460 481 0.97

4 9 0.066 5.4 7.8 1.0 2 23 489 511 488 511 0.95

5 9 2.1e-05 0.0017 18.8 3.3 1 23 517 539 517 539 0.98

6 9 0.00065 0.053 14.1 0.5 1 23 544 567 544 567 0.97

7 9 0.084 6.9 7.5 0.4 2 23 575 597 574 597 0.95

8 9 0.068 5.5 7.8 1.7 2 23 604 625 603 625 0.94

9 9 0.73 60 4.5 1.3 1 23 630 653 630 653 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.021	1.7	9.4	1.8	2	23	345	367	344	367	0.96
2	9	0.062	5	7.9	0.5	3	23	425	446	423	446	0.94
3	9	8.3e-06	0.00067	20.1	0.6	1	21	460	480	460	481	0.97
4	9	0.066	5.4	7.8	1.0	2	23	489	511	488	511	0.95
5	9	2.1e-05	0.0017	18.8	3.3	1	23	517	539	517	539	0.98
6	9	0.00065	0.053	14.1	0.5	1	23	544	567	544	567	0.97
7	9	0.084	6.9	7.5	0.4	2	23	575	597	574	597	0.95
8	9	0.068	5.5	7.8	1.7	2	23	604	625	603	625	0.94
9	9	0.73	60	4.5	1.3	1	23	630	653	630	653	0.95

Sequence Information

Coding Sequence: ATGGATTCCACATCGGTTCCGCCGCCGGCAGTGTTAACACTTAACAAGGCTAACAAAGCTAACCAAGCGAAATGCCGAGCTTGTCTCTCTGTGAACCGTAAGACTGTGAAACTGGACGCAAAAATGCCAGATCTGCAGAAGCCCAGCACCTATGGTCAGGGTCTGCGTCGGTGTACCAATTTGGAACTGAGTGTTAGTGTCACCGCCAGTGGCTATAAATTTCCAATGCAAATCTGTATCCGTTGCTGTCGAGCTCTTGAGGTGGCCATGCATTTTGTCGAAATGGCTTTGGACTCACATAGCAAGCTTTATGCCGAATCCCAGAGAATCAAACCATCTGCATCTACGGCTGCGGAAACTATAGTGGGTGAACTGAAGCGAAAGGCCAGCGACGAGTTGTTACACTGGAATCAATTTAGTCAGGAATTTGAGCAATTCGTGGAAAGCTATGACGGAGTGCCAGGTCCCATAGAAGAAAATGTTCTATATATGCGAGGAGCCAAAATGCCACGTTTAGATTCTGATGTCATGAGCAGCAGCAAGCCGCCAAAGGAGGATGACATCATATTGTTTGATGTCAAATATGATACCAACAATCAAGATGCAGAGGATGAAAACGATGGTTCCGATGCTAAGAACAATGAAACATTCTTTGAAAATAGTATTATAAATGGCCATGGAGAAGTTGATGTAGAGTCAGGAGCTGCCAGCACCAAGAGCAGCGAGAATAACAACAACAACAATAATAATAATTACAAATTTAATAATAAAAATGGCGACATGTCTGGTCTGCCTGATGTTGAATGTGATTTGATCGAACGTGCTATCTACATGACACTCAACGATGTTCCCAATTCAGATCAGAAGGAAGAGATAAAATTCAGCGATACCATGACAAATGAATCTAGTAGTGCTACTCCCACACACACAAAAGGCTCTGACAATCTGGATGAAGCCATAAAACCAGCTTCACCTCCCACGCAATTGCCAACATCTTCAGCAGTTTGGACGCCACTGCATATTCCACTTCTTAGTTGCAATATATGCAATTATACGCACAAAGAAGCCAAACAGCTAAGGAATCATTACATGACTGCCCATAACTTTGATATGCACGAAGATGATATAATTGGTCTGACCAAAAATCAAAGCTTCAAGTGTCGTCCTTGCAATAGTTATGAGACAAAAAACCGTGCAGATATGCAAAAGCATCTAATTGATCATCATAAAATTGACGGCGATTTTGAAATGTTTTGCTATGTGCAGCAGAATTGTCCAGCCTGTGCACGCGTCTTCAAGGATCAGCGCTCGGCCAGAACGCATTACACAAGAATGCACACACAACCACATAGTGAAATCTCAGAGCAGCAGCAGATATACAAATGCACTGCTTGTGATAAGGTTTTCAATCAAAAGTACGGGCTAAATGCCCATCAGCGATTCTGCCAGGAAAAGGAACCTGTACAGTGTAATTTCTGTACGGAACAATTTACCAGCATGAGGAGGTATGAGGCCCATTTGCAGCAACAGCATTCGGTGGATACATTGCATGAGTGTGAGATATGTCATAAGAATTTCAAGAATGCCGAAACTCTAGCTATCCATCGTAAACGTCATTCGGAGCGACATTATCAGTGTGACAAGTGTTCACTGAACTATATCAATGCGACTGAACTGCGCACCCATTATGAACGTGCTCATGTCCAGCATGAGACGCTGGTCAGTTGCCAGAGTTGTGACAGTAAGTTTCCAAATTTCGCCCTACTACGAGAGCACGAGCAGAGGAATCATCAGAAGCAAAAAGTCTGGCGCTGTGACAATTGCAGTTTCGAGACCAGGACTCGATTCCTTTTGCGTCAACATCAGTTTGAGCATATGGATTACCCTTATAAGTGTATTAAATGTGCCGAGGAATTTGTCGATCGTGGAAAATTTCGTTATCATTCGAAGAAGTTACATGGAATTGACCTAACCGATGACCAATTGGCTGAGATGTTTCGCGAACGCACTGGCTATACAAATCGTTACGATATATTCAACAAGACGAACAATTCACTCGAAATTCCCGGATTTAGCGACGACTGTTTCAATGAACTGAGAGATCTAGGAGTTGACTACGATGAAATCACGAATGATCTCTTTGCAAATTCCGCTGCCCTGGATAATCTGCTCGATCTTATACCATAA
Protein Sequence: MDSTSVPPPAVLTLNKANKANQAKCRACLSVNRKTVKLDAKMPDLQKPSTYGQGLRRCTNLELSVSVTASGYKFPMQICIRCCRALEVAMHFVEMALDSHSKLYAESQRIKPSASTAAETIVGELKRKASDELLHWNQFSQEFEQFVESYDGVPGPIEENVLYMRGAKMPRLDSDVMSSSKPPKEDDIILFDVKYDTNNQDAEDENDGSDAKNNETFFENSIINGHGEVDVESGAASTKSSENNNNNNNNNYKFNNKNGDMSGLPDVECDLIERAIYMTLNDVPNSDQKEEIKFSDTMTNESSSATPTHTKGSDNLDEAIKPASPPTQLPTSSAVWTPLHIPLLSCNICNYTHKEAKQLRNHYMTAHNFDMHEDDIIGLTKNQSFKCRPCNSYETKNRADMQKHLIDHHKIDGDFEMFCYVQQNCPACARVFKDQRSARTHYTRMHTQPHSEISEQQQIYKCTACDKVFNQKYGLNAHQRFCQEKEPVQCNFCTEQFTSMRRYEAHLQQQHSVDTLHECEICHKNFKNAETLAIHRKRHSERHYQCDKCSLNYINATELRTHYERAHVQHETLVSCQSCDSKFPNFALLREHEQRNHQKQKVWRCDNCSFETRTRFLLRQHQFEHMDYPYKCIKCAEEFVDRGKFRYHSKKLHGIDLTDDQLAEMFRERTGYTNRYDIFNKTNNSLEIPGFSDDCFNELRDLGVDYDEITNDLFANSAALDNLLDLIP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00604401;
90% Identity: iTF_00523986;
80% Identity: -