Basic Information

Insect: Drosophila willistoni
Gene Symbol: -
Assembly: GCA_018902025.1
Location: CM032166.1:15218089-15219833[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.1 87 4.0 0.1 3 23 37 59 35 59 0.92

2 8 0.034 2.8 8.7 0.7 2 23 121 143 121 143 0.90

3 8 8.7e-06 0.00071 20.0 1.9 1 23 159 182 159 182 0.98

4 8 4.3e-06 0.00036 21.0 2.4 2 23 279 300 278 300 0.96

5 8 0.0012 0.095 13.3 4.0 1 23 306 328 306 328 0.98

6 8 7.3e-06 0.00059 20.3 2.4 1 23 334 356 334 356 0.97

7 8 1.7e-06 0.00014 22.3 3.0 1 23 362 384 362 384 0.99

8 8 0.0094 0.77 10.5 4.2 1 20 390 409 390 411 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.1	87	4.0	0.1	3	23	37	59	35	59	0.92
2	8	0.034	2.8	8.7	0.7	2	23	121	143	121	143	0.90
3	8	8.7e-06	0.00071	20.0	1.9	1	23	159	182	159	182	0.98
4	8	4.3e-06	0.00036	21.0	2.4	2	23	279	300	278	300	0.96
5	8	0.0012	0.095	13.3	4.0	1	23	306	328	306	328	0.98
6	8	7.3e-06	0.00059	20.3	2.4	1	23	334	356	334	356	0.97
7	8	1.7e-06	0.00014	22.3	3.0	1	23	362	384	362	384	0.99
8	8	0.0094	0.77	10.5	4.2	1	20	390	409	390	411	0.93

Sequence Information

Coding Sequence: ATGTGTTCGACCACCACAGTGCTGTGTCCTTTGTGCGCTGTGCCCAGTTTTGGTAGCATTGATGCGCTGCAGCAGCGTTTAATAAAGGCAGCCAATGGCCCATTGGCATGTCCATTTCCCAATTGCAAAGAAATGTTCTTGGGTTTGGATAAATTGACAATACATTTGTTCACGCACACCACTCTAATGGCAGAGAGCCCAACACCTGTCGGAGTGAATGCCTCGGCCAAACGGGGCAGAAGTAAACGATCAAAGGTTAAGCCTGTAGAGCAAGTTGCTCCACCACTAGTAGTAGCAACCTTGGAACCTATTCAGACACCACCTGCACCACCAACACCAGCACCACCCGTAACGCCGGCACGTTGCGATATCTGCGAGTTTAGCTTTCGGAATAACGATCTGCGTGACATGCATTTCCGTTTGGTTCATGAGAATGCCGAGGAGCAAATCAAATTGGGCCAAGAGCAGGAGCCCTACAAGTGTCATCTTTGTGCCAAGACATTTCGCATGAAGGGTTCGTTACGGGTTCACCTTAAGGTGGTCCACATGATGGGCATGTCCAGTTCTAGTATCAACATGACCAACTCTAGTCCAGGTCAGAAGCCATTAAATGCCAATCCCTCGCCCAAAATAAACATATGCGACCGGATACGTCACAAAGAGGCGGCAGCCAGTGGCAATGTGAGCTCAGCTAGCACTAGTACCCAACCGTATGCATTGAGTGGAGCCTTGTGTATGCTCCAACAGACACCAGCGCCGCATCAGACATCAGTGCTTGCTGCCGATTCATCGCCAGAACCATTAGCTGGAGGCATCGTCACACCCAAAGTCTGGGAATGCGATGTCTGCACTAAATCCTTTACTACCAAGTATTTCCTAAAGAAACATAAGCGCCTGCACACTGGTGAGATGCCCTACACCTGTGAGATTTGCGCCCGCACCTTCACGTTCCAACAGTCGTACCACAAGCATTTGCTCTATCACAGCGAAGTCAAGCCGCATGTGTGTTCCGTCTGCGGGCGAGCTTTCAAGGAGCTATCCACTCTGCATAATCATCAGAGGATTCACAGTGGTGAGAAGCCCTTCAAATGCGAAGTTTGTGGCAAATGTTTCCGTCAACGTGTCTCCTTCTTGGTTCACACACGCATTCATACTGGAGTCATGCCATACAAATGTGAACTGTGCCAGAAAACGTTTCGTTACAAGGTCTCACAGCGTACACATAAATGCCTCACGGAGGGAGAGGCGGCACTGCAGCAACATCAACCACATCATGAGCAGCTGCCCCAACAGACGCCCGAGCAATTGATTAAGGCATTTCTAGAGAACAATGAGTCGCAGCACTCACAACAGTCGCCGGCAAGTGCCGAGATAGCATCCATCACGAGTGGAGCTCATGAGGAGGCTTTACTATCGCAGAGCATCGATGACATTGTGGTGGAGCAGTGCCAGAAATTGGGCATCTGTGGACTGGTACCACAATTGCCACCGGCGCCAGTTCCAGTGCCGGTGCAAGTACCCCTCGAAGCAGCCGGTTTGCCACAGTTCAATGGAGGCGGCAGCAGTTCACCGCTGCAGCAATTACAGAATTTACGTCTTTATTCGCCGCAGCATGTTGAGATGCCTAGCTCGGGCTCGGATGGGGAAATCTTCGGACGTTTCCTAATGGACGCTAGTTAA
Protein Sequence: MCSTTTVLCPLCAVPSFGSIDALQQRLIKAANGPLACPFPNCKEMFLGLDKLTIHLFTHTTLMAESPTPVGVNASAKRGRSKRSKVKPVEQVAPPLVVATLEPIQTPPAPPTPAPPVTPARCDICEFSFRNNDLRDMHFRLVHENAEEQIKLGQEQEPYKCHLCAKTFRMKGSLRVHLKVVHMMGMSSSSINMTNSSPGQKPLNANPSPKINICDRIRHKEAAASGNVSSASTSTQPYALSGALCMLQQTPAPHQTSVLAADSSPEPLAGGIVTPKVWECDVCTKSFTTKYFLKKHKRLHTGEMPYTCEICARTFTFQQSYHKHLLYHSEVKPHVCSVCGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTGVMPYKCELCQKTFRYKVSQRTHKCLTEGEAALQQHQPHHEQLPQQTPEQLIKAFLENNESQHSQQSPASAEIASITSGAHEEALLSQSIDDIVVEQCQKLGICGLVPQLPPAPVPVPVQVPLEAAGLPQFNGGGSSSPLQQLQNLRLYSPQHVEMPSSGSDGEIFGRFLMDAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00555323;
90% Identity: iTF_00612301;
80% Identity: -