Dwil014526.1
Basic Information
- Insect
- Drosophila willistoni
- Gene Symbol
- -
- Assembly
- GCA_018902025.1
- Location
- JAFEWB010000731.1:1554485-1556079[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.063 5.1 7.9 1.5 1 20 48 67 48 68 0.92 2 10 0.00044 0.036 14.7 1.7 2 23 99 120 98 120 0.97 3 10 6.7e-05 0.0055 17.2 0.4 1 23 146 167 146 167 0.98 4 10 0.0043 0.35 11.5 1.0 2 23 176 197 175 197 0.96 5 10 0.0032 0.27 11.9 0.4 1 23 223 245 223 245 0.98 6 10 3.9e-07 3.2e-05 24.3 0.5 1 23 251 273 251 273 0.98 7 10 0.0008 0.066 13.8 5.5 1 23 279 301 279 301 0.98 8 10 5.4e-06 0.00044 20.7 0.8 1 23 307 329 307 329 0.98 9 10 5.3e-05 0.0043 17.6 0.1 1 23 333 355 333 355 0.96 10 10 0.0032 0.26 12.0 0.2 3 23 377 398 375 398 0.98
Sequence Information
- Coding Sequence
- ATGGAAACTGAATATATAGAAACTGAGGAAATGGAGGAAGTCCACGAGGATTCCGAGCCACCTCTCTGGGAGCTAGTGGAGGAGGAAGAGGTGCCAGGGACTTTTGATCTATGCGAAGAAGAGCTTTCCGAATCGGAGAGATATTTTTGCTATGATTGTCATAGAATTTTTGAGAATCGCGTGTCCGCCGAGGAGCACATATGCCCGCAGGCGGGTCAAACGGAAACGGAGACTGCCGAACCCCCAGTGGAAGTCACTCCAGCTCCAGCTGTAGTTGCCAGAAATATGCAAGTCACCTGCCACATATGCAACACGATCTTTGGTTCAAGCAAAGCCCTCAAGTTCCACATGCGCATGCATGGCAAGGTGTCGACTAAGAGCATACAGGATGCCCTGCCAGTAGGAGCTCATCAGCAGTACAATCAGCTTGATCAGTTTTACTGTGAGATCTGCAATAAGAGCTTTGATGAGAGCTTGTTGGCTGTGCACAAGCAGATGCATCAGGAATCTTCGTTGGAACAGCTCATGTGCAGAACCTGTAATCGCAAGTTCGACAATGTAAACGAATACGAGATGCATTTGAAAATGCATGAGAAACAGACGGATAAACCTACCTCACGTCCAGTGCCATCCAATGGCAAGAAGATTAGATCTGATAAACCTGGATATCCATGCCAATATTGTGAGCGCGTGTTCCTGCGACCCTATGAGAAGGTGAAACATGAACGTGTACACACGGGGGAAAAGCCTTACGCCTGTGAAGTGTGCGGGAAAACCTTTCGTGTAACCTATTCCTTGACTCTTCATTTGAGAACGCACACAAACATCAGACCTTATGTCTGCACAGTGTGTAATAAACGCTTTAAATCGCATCAGGTGTATTCCCATCATTTGCGTATCCATAGCTCGGAGAAGGAATATGCCTGTGATAAGTGCCCAAAGACATTTCGCACTTCGGTGCAATTGAGTGGCCATAAGAATACCCATACCAAACCCTTTGAATGTACCATCTGTAATCGTCCCTTTGCCTCTTTGTACGCGGTCAAGGCGCACATGGTTAATCACAAAGACAAGGCCCAGGAAGGGCAGGGAGCCAGCAAAAAGCCTTCCACAAATGGCAAATTCTGGTGCACGGTCTGTGGAGCTGAATATTCGCGTATATTTGCCTATCGCCAGCATTTGAAGACGGCTCATGGTCAAAGTGAAGATAATGGGGAGAAGAAACCTCGTCAATTGTTGGAGGAGGAGGGTGGAATCGATGATACTGAAGCAGCTGCTCTCAGAGCTGCAGCCGATGCAGATGCTGCCTATATGCTAAGTGATGTGACTGTCGTTGACACCATTCCCACTTTGGAAGAGTTTGATGTGGAAAATCTTCACACCGAAGAGATCATCACTGATTGGCTTACATGA
- Protein Sequence
- METEYIETEEMEEVHEDSEPPLWELVEEEEVPGTFDLCEEELSESERYFCYDCHRIFENRVSAEEHICPQAGQTETETAEPPVEVTPAPAVVARNMQVTCHICNTIFGSSKALKFHMRMHGKVSTKSIQDALPVGAHQQYNQLDQFYCEICNKSFDESLLAVHKQMHQESSLEQLMCRTCNRKFDNVNEYEMHLKMHEKQTDKPTSRPVPSNGKKIRSDKPGYPCQYCERVFLRPYEKVKHERVHTGEKPYACEVCGKTFRVTYSLTLHLRTHTNIRPYVCTVCNKRFKSHQVYSHHLRIHSSEKEYACDKCPKTFRTSVQLSGHKNTHTKPFECTICNRPFASLYAVKAHMVNHKDKAQEGQGASKKPSTNGKFWCTVCGAEYSRIFAYRQHLKTAHGQSEDNGEKKPRQLLEEEGGIDDTEAAALRAAADADAAYMLSDVTVVDTIPTLEEFDVENLHTEEIITDWLT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00571331; iTF_00612242; iTF_00503422; iTF_00555258; iTF_00604263; iTF_00523859;
- 90% Identity
- iTF_00523859; iTF_00571331; iTF_00612242; iTF_00503422;
- 80% Identity
- -