Basic Information

Insect: Drosophila willistoni
Gene Symbol: -
Assembly: GCA_018902025.1
Location: JAFEWB010000700.1:8012661-8015015[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.018 1.5 9.6 8.9 3 23 262 282 260 282 0.97

2 12 0.0022 0.18 12.4 0.5 1 23 288 313 288 313 0.94

3 12 4.2e-05 0.0034 17.9 1.4 1 23 320 345 320 345 0.96

4 12 0.00017 0.014 15.9 3.5 1 23 354 376 354 376 0.97

5 12 1e-05 0.00084 19.8 0.1 1 23 383 405 383 405 0.97

6 12 0.012 0.97 10.2 0.4 1 23 411 433 411 433 0.97

7 12 0.0011 0.093 13.4 0.8 1 23 439 462 439 462 0.97

8 12 0.0082 0.67 10.7 3.7 1 23 468 490 468 490 0.96

9 12 4e-05 0.0033 17.9 1.0 2 23 497 518 496 518 0.97

10 12 4e-05 0.0032 18.0 1.0 1 23 592 615 592 615 0.96

11 12 0.028 2.3 9.0 6.5 1 23 621 643 621 643 0.94

12 12 9.4e-05 0.0077 16.8 1.8 1 23 649 671 649 671 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.018	1.5	9.6	8.9	3	23	262	282	260	282	0.97
2	12	0.0022	0.18	12.4	0.5	1	23	288	313	288	313	0.94
3	12	4.2e-05	0.0034	17.9	1.4	1	23	320	345	320	345	0.96
4	12	0.00017	0.014	15.9	3.5	1	23	354	376	354	376	0.97
5	12	1e-05	0.00084	19.8	0.1	1	23	383	405	383	405	0.97
6	12	0.012	0.97	10.2	0.4	1	23	411	433	411	433	0.97
7	12	0.0011	0.093	13.4	0.8	1	23	439	462	439	462	0.97
8	12	0.0082	0.67	10.7	3.7	1	23	468	490	468	490	0.96
9	12	4e-05	0.0033	17.9	1.0	2	23	497	518	496	518	0.97
10	12	4e-05	0.0032	18.0	1.0	1	23	592	615	592	615	0.96
11	12	0.028	2.3	9.0	6.5	1	23	621	643	621	643	0.94
12	12	9.4e-05	0.0077	16.8	1.8	1	23	649	671	649	671	0.99

Sequence Information

Coding Sequence: ATGGAACCGAAACGTGGTGAATACTCCATACACAGCGTCTGTCGCACTTGCCTGGCCACATTGGAGAATGTGATGGCTTACGATCTGTTCCTTACACCAGGATTGGCCAAGAAGCTGTGTATCTGCACTTCATTGTCGGTGGAGTCACAGGATGGTTTCCCAAAGAATCTCTGCATCAATTGCTTTACCAAGTTAAACGATTTGAATGACTTCCAGAAAATGTGCGTCGATTCGGTTCAGAAGTTCCAGGAAATGGTCGCTAGCCAGGCATTTACAACCGGAGGTCCTGAGTTCGATGTCCCACCTGACGATCCGGAAGAAGACATGAATTTTGATCCCTTGCTGCATTCGAAAGTGGAGACCATGGACAATGAGGAGGAGGTTATTAAAATGCTTGAAAAGGTAGACAAAGAACCAGAGGACAAGGAGGAATATGATGCATTTGCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCTTCCATTGGCGCAAAGAACAAAGCGAAGCAAAAAAGATATTAAAATGCCAAAAAAGGCAACAAAAAAACAAAACAAGTCTAAGAAGGAGCCCTCAGAGAAAGGCGAGGAAGAAGAGGAGGAGGAGGAGGAGGTTGACAATGCATCTTCCTCTGACACCGAATCAAACAATGCTACTACTAAAGTTAAGCCCAAACGCAAGAGGATTCCAGCCGATGAGCGTCATTTGCATCGTCTAATCGATTGCCACATTTGTCATCAGAAGTTCAAGAAGGCCTCCTGTTACGAGGAGCACATGAAACATCATAACGATCTCTTACCCTTCCAGTGTACGGTCGAGTCATGCCGCAAGGGATTCACCACAGCCAATGGCCTCAAAGTTCACATAGAGCATGCCCACACCGAGGAATCCAAAATGCATCGATGTACTGTGGAGGGATGCAACCGAACCTTTGCTCGTCTATCTCTACTCAATGTTCATCTGAAGCGTACGCACAAATTGAAATTACCCCCACGTGAATTCCCCTGTTCGGACTGCGACAAAATCTTTCGATGTCAGACTGCTCTTAAGAAGCATATGTATAAGCATACGGGAAGGGAATTGCCATTTGCCTGTGAGATCTGTGGCAAGCGATTCCCCATTAATAGCGCTCTAAGAGATCATTTACTACGCCATGCTGGCATCAAGAATCATGTCTGCCCCTATTGCGGGGTGGGCAAAACCACACGCCAGGAGTGGAACAATCACATTCTAACCCATACCAAAGAAAAGAAATTCCAATGCCAACTCTGCGATCATGCTTCGACCAACAAGCAAGCTCTTAGCAACCATGTCAAGGTTGTCCATATGAAACGCAAAGATTTCGCTTGCCAATATTGCGGCAAAACCTTTGGCAAATCCTTTTCCTGTAAAGTCCATGAGCGTAGTCACACTGGTGAGAAGACTAGCGAATGTAAGATTTGCGGCAAGATCTTTCTGCAGGAGAAGAGCCTTACCAAGCATTTGAAAACCCACGAAAAACGCGAATTACCCAAGCCGGGAGATGGTGCTAGCGATGAAACCACAGCACAGGCCAAACCTGAACCCAAGAAGAAAGCCTACAATTCGGGACGCGTTGAGCGGGTAGACATATCCCAATTGGCTGGCACAGCTATTAATCCCATAACCTCTGTCTCTCTACCGTCATGGTCTCCAGCACAAAGTGGCGACCCGTTTAGCAAAAAGGAAGGCCAACACATTTGTCCCGATTGCGGCAAGGGTTTCAATCACATTGGCAACATGAAACTCCATTACAAAGTGGTCCATCTGAAGGTCAAAGATTTCTGTTGTCGCTTCTGTCCCAAGCGTTTTGCGAAGAAGCATTATCTCCGCGAACACGAATACATTCACACTGGTGAGAGGCCCTATGAGTGTAAGGTCTGTGGCAATCGTTTCCGTCAAGAGTGTGTCCTGAAGATCCACATGAAAGTCCATAATAAGCCACCAAAACCGCCCAAACCACCGGCTAAACCAAAGAGCAACAAGCCGAAAACTGAAAATCCACCAAATAAACGCCAACCACCATTCGAACAATTCCAAGATCCAGCTGCTGAGCGTGCCGCAGCCTCGGCCGAGCTATTGGCCTACCAAATCGAGGAGAATGAATCCAAGCGCAAGGCAGAGTTGGAGCAGCGCAAGATTCAGGAAGCAGCAGTGGAGCAGCTAAGCAAACTGGAATTACTACAAACCCCGGTTAATACCTATAACAGTTTGTATGCCCAAAAGTCTGCCGAGGAACGAAGTACAGTTGATGCCCTCAAATTGGATCATGTGTAA
Protein Sequence: MEPKRGEYSIHSVCRTCLATLENVMAYDLFLTPGLAKKLCICTSLSVESQDGFPKNLCINCFTKLNDLNDFQKMCVDSVQKFQEMVASQAFTTGGPEFDVPPDDPEEDMNFDPLLHSKVETMDNEEEVIKMLEKVDKEPEDKEEYDAFAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLPLAQRTKRSKKDIKMPKKATKKQNKSKKEPSEKGEEEEEEEEEVDNASSSDTESNNATTKVKPKRKRIPADERHLHRLIDCHICHQKFKKASCYEEHMKHHNDLLPFQCTVESCRKGFTTANGLKVHIEHAHTEESKMHRCTVEGCNRTFARLSLLNVHLKRTHKLKLPPREFPCSDCDKIFRCQTALKKHMYKHTGRELPFACEICGKRFPINSALRDHLLRHAGIKNHVCPYCGVGKTTRQEWNNHILTHTKEKKFQCQLCDHASTNKQALSNHVKVVHMKRKDFACQYCGKTFGKSFSCKVHERSHTGEKTSECKICGKIFLQEKSLTKHLKTHEKRELPKPGDGASDETTAQAKPEPKKKAYNSGRVERVDISQLAGTAINPITSVSLPSWSPAQSGDPFSKKEGQHICPDCGKGFNHIGNMKLHYKVVHLKVKDFCCRFCPKRFAKKHYLREHEYIHTGERPYECKVCGNRFRQECVLKIHMKVHNKPPKPPKPPAKPKSNKPKTENPPNKRQPPFEQFQDPAAERAAASAELLAYQIEENESKRKAELEQRKIQEAAVEQLSKLELLQTPVNTYNSLYAQKSAEERSTVDALKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00571333;
90% Identity: iTF_00571333;
80% Identity: -