Basic Information

Insect: Drosophila willistoni
Gene Symbol: -
Assembly: GCA_018902025.1
Location: JAFEWB010000697.1:13491026-13493194[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.11 8.9 7.1 0.5 3 23 321 342 320 342 0.92

2 10 0.0002 0.016 15.7 0.5 6 23 351 368 351 368 0.99

3 10 8.9e-06 0.00073 20.0 0.3 1 23 374 397 374 397 0.98

4 10 2.4e-05 0.002 18.6 0.7 1 23 409 431 409 431 0.97

5 10 5.3e-05 0.0043 17.6 3.0 1 23 438 461 438 461 0.96

6 10 1.2e-05 0.001 19.5 1.8 1 23 467 489 467 489 0.96

7 10 0.16 13 6.6 1.0 2 23 498 519 497 519 0.96

8 10 6e-05 0.0049 17.4 2.9 3 23 526 547 524 547 0.95

9 10 3.1e-07 2.5e-05 24.6 0.7 2 23 554 575 553 575 0.96

10 10 0.00019 0.015 15.8 4.4 1 23 581 604 581 604 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.11	8.9	7.1	0.5	3	23	321	342	320	342	0.92
2	10	0.0002	0.016	15.7	0.5	6	23	351	368	351	368	0.99
3	10	8.9e-06	0.00073	20.0	0.3	1	23	374	397	374	397	0.98
4	10	2.4e-05	0.002	18.6	0.7	1	23	409	431	409	431	0.97
5	10	5.3e-05	0.0043	17.6	3.0	1	23	438	461	438	461	0.96
6	10	1.2e-05	0.001	19.5	1.8	1	23	467	489	467	489	0.96
7	10	0.16	13	6.6	1.0	2	23	498	519	497	519	0.96
8	10	6e-05	0.0049	17.4	2.9	3	23	526	547	524	547	0.95
9	10	3.1e-07	2.5e-05	24.6	0.7	2	23	554	575	553	575	0.96
10	10	0.00019	0.015	15.8	4.4	1	23	581	604	581	604	0.96

Sequence Information

Coding Sequence: ATGATATGTCGTTTGTGCTTGCGGAGCATAAATGCCAACACTGCCGTTTTCCTGTTTGAGACCAACGAAACTCTGGCGGAGACGAGGCTGGTCAAGATGATAGCTAAATTTCTTCAGCTGGAGATTATGCCGGATGACAGCATCTCGACCAGCGTCTGTACCGTATGCTGTGAGCACCTGGAGGATTTCAATAGCTTCTGGCAGTTGGTGGAGCAAAAGCAGGGAACTTTAAAAAAGGAATTTCTTACTGTAGATGTAGACTGTGGCGTCATGAAATGGTCTTCAGGTGATGGGGATATGGATGTGGTCGATGTGAATGCTGATGAATTGCCTGTAGTGAGTGTAAATATGGATGAGGATGAGAAGCCGCTACCGCTCGACATGCACAATCTAAGTCTGCTGGGCAGCGTCTTGGATGTTAATGTCGATGGGCAGAACGAGGAGCTAGAACAAGAGATGTCATCAGTGTTGATTAAAAAACAAAAGCCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAAAGCCCATGCTTGAGGCCAGTGGAAGTGAATTTGGAGAAGCAGACATGGTAGATGCAGAACAACTAGAAGATGATTCTTCGGATGATGAGCCTTTGGTTAAACTGGTAATGCAGTCCAGCAATCTCAAGCCGAAACGTAAATATACCAAGAACAAACAACGCCTTAGTCTTGCTATGGAACTGAAAGATTTACTCAAAGAAGATTGCTCCAATAAATCATTGTCACACCGTCGCCGCAAGGTGGCTCAACCAGCTCGCCGGGACAGTCCAACTGAAACACAGGAGAGCGAACTCCAAGCGGCATTGGAACGTAAACCAAAAGGCTGCTCTAGGGCCCAATTGACCAAACGATATGAGGAGGTCATTGCCAGCTATATGAGTGCCAATTGTGATCTATGTGATTTCAGTGGCAAATTCCTATCCGAACTGAAGACGCATTTCCAGGAGGTGCATCAGCGGGAGTTTTATATTAAATGCTGTAATAAAATATTCACACGGGCCTCCAAGCTAATGGATCACATACGAAAACATGTCAATCCCAAACTTTTCACCTGTTCGATTTGCAACAAATCGCTAAACTCACAGGATTACCTGGCCACTCACATTGAGACCGTGCACAATAAAGTGGATCAAATTGGCAAAGTGTTGAAATTTCCCTGTCCCAAATGTGAGCGAACTTTTAGCAGTGAGCGGCGATTGACAAATCATTTGGCCAAGCATGATACGGATCAGTTGGAACATAGTTGCGATATATGCCAAAAGAGCTTTGCCAATGTCCATCGCCTGCGCCGTCACATACAGTCCATACACGAAGATCTTCATCCACACGTTTGTGATATTTGTGGCAAGAAATTTAAATTCAAACCATCATTTGAGCGTCATCTGCTCGAGCATCAGGGTGTCGTTGCACCAGCCATGGAGTGCACCATTTGTGGTGTTTGGCTGAAAAATGAGCATAGCTTGCGTTTACATCGATTCACCCATGACAATACCGACACGATTTGTCCACATTGCTCGAAAACCTGTACATCGCGTACAGCATTGCGTGCCCATATTAAATATGCCCATAAATTGACCACAAATCTACAGTGTACATATTGCGATAAAAGTTTCAAACAACAGCGAAATTTGGATGAACATATGGCCATTCATACGGGTCTCCAGCTATACAATTGTCCCCACTGCCCCAAGGAGTGCCGTTCGCGTTCCAATATGTATGTTCATATCAAGCAAAGGCATGCGGACGAATGGTTAAAAGCCAAAATGGCTCGTTCTCATAATCCCCAATTGAAACCGCATACCCAAAGCTGA
Protein Sequence: MICRLCLRSINANTAVFLFETNETLAETRLVKMIAKFLQLEIMPDDSISTSVCTVCCEHLEDFNSFWQLVEQKQGTLKKEFLTVDVDCGVMKWSSGDGDMDVVDVNADELPVVSVNMDEDEKPLPLDMHNLSLLGSVLDVNVDGQNEELEQEMSSVLIKKQKPXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPMLEASGSEFGEADMVDAEQLEDDSSDDEPLVKLVMQSSNLKPKRKYTKNKQRLSLAMELKDLLKEDCSNKSLSHRRRKVAQPARRDSPTETQESELQAALERKPKGCSRAQLTKRYEEVIASYMSANCDLCDFSGKFLSELKTHFQEVHQREFYIKCCNKIFTRASKLMDHIRKHVNPKLFTCSICNKSLNSQDYLATHIETVHNKVDQIGKVLKFPCPKCERTFSSERRLTNHLAKHDTDQLEHSCDICQKSFANVHRLRRHIQSIHEDLHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECTICGVWLKNEHSLRLHRFTHDNTDTICPHCSKTCTSRTALRAHIKYAHKLTTNLQCTYCDKSFKQQRNLDEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQLKPHTQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00503425; iTF_00600482; iTF_00571332; iTF_00501229; iTF_00523860; iTF_00612248; iTF_00577949; iTF_00483877; iTF_00556000;
90% Identity: iTF_00556000;
80% Identity: -