Basic Information

Insect: Drosophila willistoni
Gene Symbol: -
Assembly: GCA_018902025.1
Location: JAFEWB010000731.1:7442061-7448523[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0002 0.017 15.7 3.4 1 23 287 309 287 309 0.98

2 11 0.00099 0.081 13.6 10.5 1 23 316 338 316 338 0.96

3 11 0.0001 0.0082 16.7 6.5 1 23 344 366 344 366 0.98

4 11 0.0003 0.025 15.2 2.3 1 23 372 394 372 394 0.95

5 11 2.2e-05 0.0018 18.8 0.5 1 23 400 422 400 422 0.97

6 11 7.2e-06 0.00059 20.3 0.1 1 23 428 450 428 450 0.98

7 11 6.8e-05 0.0056 17.2 2.0 1 23 455 478 455 478 0.97

8 11 0.00078 0.064 13.9 0.2 1 23 484 507 484 507 0.94

9 11 0.00016 0.013 16.0 0.1 1 23 561 583 561 583 0.98

10 11 0.015 1.2 9.9 2.7 1 23 699 721 699 721 0.95

11 11 0.0044 0.36 11.5 4.9 5 23 734 752 726 752 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0002	0.017	15.7	3.4	1	23	287	309	287	309	0.98
2	11	0.00099	0.081	13.6	10.5	1	23	316	338	316	338	0.96
3	11	0.0001	0.0082	16.7	6.5	1	23	344	366	344	366	0.98
4	11	0.0003	0.025	15.2	2.3	1	23	372	394	372	394	0.95
5	11	2.2e-05	0.0018	18.8	0.5	1	23	400	422	400	422	0.97
6	11	7.2e-06	0.00059	20.3	0.1	1	23	428	450	428	450	0.98
7	11	6.8e-05	0.0056	17.2	2.0	1	23	455	478	455	478	0.97
8	11	0.00078	0.064	13.9	0.2	1	23	484	507	484	507	0.94
9	11	0.00016	0.013	16.0	0.1	1	23	561	583	561	583	0.98
10	11	0.015	1.2	9.9	2.7	1	23	699	721	699	721	0.95
11	11	0.0044	0.36	11.5	4.9	5	23	734	752	726	752	0.92

Sequence Information

Coding Sequence: ATGTGCGCTGCACAGAGCAATCCGCCGCCCTTCGGCTACACTTGGGGCTTTGCAGACAACGGCAGCCGTACCGCCGAATCGGTATTGGAAATATCGCCAAATATTAATTACACCGTTAGTGGGGAATCGATGCCCTATCTGTTATCCACGGATGGATCATTGGCCGTACAAAAGGATGTTAAAGGTGCACTGGCTGGCAATAAGGCGAATGTTGTGCGTCGCATGTTCTTGGTGAACGATTCCTCATTTCCGCACGGTACACAAAGAGTAATTACCACAGGTGCCACCTCGACGGTGGTGAAGAAACAGGACTCAACCACTCAACAGGTGTTGAGTATAAATTCACTCGATAAGAACTATCTTCTGGTCGATCAGGCCACAGCCGCAGCTGCAGCAGCTGCCGGTGATCCAACGGCTCATCATCATACATTGACGAATGGTAGCATTGTTGATGCCAAAACAGGACAAACCGTTTTGAGTTCGGGGGCCGCAGCTGCTGCTGCTGCTAAATCCCATTTCGGTTCCATTGGTGCACTGCATCTAACGCAAGAGGAGTGCAATGAGATATTGATAAAGCGCGCCATCGCTGCCGGCCACCATCAGACGCACACAATCACCACCGCCGACGGAGCGCATCATCATAGCACGGCGCCAGGCGCGACACCAAGTGACCTACTTCCTGGTATTTCAGTTCAAGTACAGAAAGTAATACAAGGACTCGAAGAGAACGAGGACTCACAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAGTTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACGGACGCCACTATCAAGAAGGAACGCCCGTACAGTTGTGACGAGTGCGGCAAGTCCTTTCTGCTCAAGCATCATTTGACCACACACGCCCGCGTCCACACAGGTGGTGAACGTCCACATATCTGCACCCATTGCGGTAAAAGTTTTGCCCACAAACATTGCCTAAATACCCATCTGCTGTTGCATTCAACGGATCGCCCATATCAGTGCCAGGAGTGCAAGAAAAGTTTTACCCTTAAGCATCATCTGTTGACGCATTCACGTGTCCATAGCCGGGAACGGCCATTTGTGTGCCAGGAGTGTGGACGCTCATTTCCATTGAAGCGTCATCTGGTCACTCATAGTAAATTTCACGCAGGCGAACGTCCATACGTCTGTGAGGAATGCGGTGAGAGTTTTGCCCAGGAGAATCATCTGATTATGCACTCGCGCTTTCACGGGTCATTGAATCCATTTGTTTGCTCTGAGTGCGGTGCCTCGTTTCCACGTAAATTTCAATTGGTTAATCACGGACGTATACACGGCAAGATACCACATTCGTGTACAATTTGTGGTAAAGAATTTCTTCAGAAGCGCACACTAGTTTCCCACATGAGGCGCGTACATACGGGCGAGCAGGCGCATCCCTGCGTGAGTTGTGGCGAGGGTTTCCCCACAAAGGCCGAACTGCATCAGCATGTTCGTGCCGCTCACAATGGTGTTAATCCCAATACAAGTAGCGCCACCATAATAGCTAATCAACAGCAGCTACAACAGCCTCACCATCACCCCGGGCATCCGCAGACCATAACTGTTGTCAGTAATCCGGTAACAGTGTCCATAACCGATGCCAATGGTGTGGCAAGACCGCAATTTGTTTGCCGTGAGTGCGGCAGCGCCTTTAATAGCCGCGAAGCATTGGCCCTCCATTTGCGTTTGCATACTGGCGATAAAAGCCTAATGACCGATTTGTGCGCCCTGACGGCAGCTATACCAGGACATTTCCTGAGCACGGCAAGTCTTAATCCAGGCACTGTGGTAGCAGCCAATCCAAATTTGGTTGGACAGAGTCCGGTGCCAGTGCAAATTATTTCGTCCACCGGCCAGTTAATGTCACAAACCACGCTGGTGCAGGCCGCCAATTCGACCCATCCGCAGGTTGTCACCGCTGTGCCCCACATGCCATTGCATGCCACACAACAGCAGCATTTGCAGCATGTTGGCGCACAACAGCAACAACAGCAGCAACAACTTGTTCCCGCTGCGCCGGCCAATAAACCAAAATCGCATTTTTGTGCCAGCTGCGGCAAGGGATTCGCTGCCAAGCATGGTCTAATGCAGCATAATCGGCGACATCCCAACGGCGGTTGCACGGTCCGCACCCATGTCTGTGAGTGTGGCAAGGCATTCTTCCAGAAGAATCATCTGATGCTGCATCAGCGCCAGCATTTGGAAACAAAGCCAGCCATATCCCAGCAACAGGTATGCTAG
Protein Sequence: MCAAQSNPPPFGYTWGFADNGSRTAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGALAGNKANVVRRMFLVNDSSFPHGTQRVITTGATSTVVKKQDSTTQQVLSINSLDKNYLLVDQATAAAAAAAGDPTAHHHTLTNGSIVDAKTGQTVLSSGAAAAAAAKSHFGSIGALHLTQEECNEILIKRAIAAGHHQTHTITTADGAHHHSTAPGATPSDLLPGISVQVQKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICTHCGKSFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRSFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCSECGASFPRKFQLVNHGRIHGKIPHSCTICGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFPTKAELHQHVRAAHNGVNPNTSSATIIANQQQLQQPHHHPGHPQTITVVSNPVTVSITDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAAIPGHFLSTASLNPGTVVAANPNLVGQSPVPVQIISSTGQLMSQTTLVQAANSTHPQVVTAVPHMPLHATQQQHLQHVGAQQQQQQQQLVPAAPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQVC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01556276;
90% Identity: iTF_00523858;
80% Identity: -