Dwil004927.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila willistoni
Gene Symbol
-
Assembly
GCA_018902025.1
Location
JAFEWB010000714.1:19302179-19304200[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00069 0.057 14.0 1.0 1 23 42 65 42 65 0.96
2 10 0.00034 0.028 15.0 0.8 1 23 274 296 274 296 0.99
3 10 5.7e-07 4.7e-05 23.7 2.0 1 23 302 324 302 324 0.99
4 10 1.4e-08 1.1e-06 28.8 0.5 1 23 330 352 330 352 0.99
5 10 2.2e-05 0.0018 18.8 2.2 1 23 358 380 358 380 0.98
6 10 0.00033 0.027 15.0 0.0 1 23 387 409 387 409 0.97
7 10 0.00064 0.053 14.1 1.2 1 21 415 435 415 437 0.96
8 10 3.5e-08 2.9e-06 27.6 0.7 1 23 443 465 443 465 0.98
9 10 8.5e-08 6.9e-06 26.3 2.8 1 23 471 493 471 493 0.99
10 10 2.6e-08 2.1e-06 28.0 0.2 1 23 499 521 499 521 0.98

Sequence Information

Coding Sequence
ATGGCCGTGCAATTGAAGCATAATTATCATCATTTACCATTGACCATAACTCCGATATTCAGTGCCCAACAGCAGCAACAGCAGCAGCAGGTGATAGCCGCTCCTTCTCAACCGGATTTAACCTTCCATTGCACCGGCTGCTCAGAATATTTTGTTAATCCTTGGGCATTATATCAGCATATGAATAACAAGCATCCGCAGGAGGAGGAAATCAAACCGGAAAACATTAATGATGACGACAAATGTCCCCAGGACGATGGTGAAGATTATAGCTGGATATTTGAACCGCTTTGTGAGCTACAAGAGAACGAAGAGATAACCGAATCTGTGGAAAGTGCTGATTCTTCGACAGAGGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAGCAGTAGCAGCAGTAGTAGCTCTAGCTCCTCATCAACAACAAGTTCCAGTCAGAGTTCGGCGTCAACTTTACCCACCACCAACGCCAACACCATTAATACCATCAATACTAATTCGACAAATTCCAACTCGTCGAAGACTGAACCCTTAAGGGGTCTAATTGCCAGCTCCAAGCCCAATGAATTTCATTTACAGATCAATGATCCGCGAGAGTCTACATCGATTATATTGCTAAAACCTGAAATGAGTATTATAGCTATACCGCCGGCTATGACGCCGCTTGTGACACCGCCAACGCCTCCATCGCCCATCGCAGCAATCGCTCAGAATCCCAAACGTCGTGGACGTCGCAGTGTGGTTCCAAATCCTTCCATAAATGCAACACTCCAGCCAAAGTGTTTTCAATGCTCTCATTGTGAGGCTAGTTTTCTAAATGCCGGCGACCTTTCCAAACACGTTCGCTCCCATATTACCAATAAGCCCTTCCAGTGCTCCATATGCCAAAAGACTTTCACTCATATCGGAAGTTTAAATACTCATATACGCATTCACAGTGGCGAGAAGCCATACAAATGTGAACTCTGTCCAAAGGCCTTTACCCAGTCGAGCAGTCTGATGGTACACATGAGATCCCATGCTGTACGCAAGCCCCATCAGTGTCTACAATGCGATAAGGGTTTCATCAACTATTCCTCGTTGCTGTTGCATCAAAAGACTCACTCGACACCGGAGGAATTGTTCATTTGCCCGGAATGTGAGAAGGAATTCAAAGCGGAGGCCTTGCTAGATGAGCATATGCTAATGCATACCCAGGAGCTGGTCTATCAGTGTGCCATTTGTAGGCAGGCATTCCGTGCCAGTTCGGAGCTGGTGCAGCATATGAAATGTCATCTGGGTGAGAAGCCATTTACCTGTAATCTCTGCGATCGCTCGTTCACCCAATCGGGCAGTCTGAATATCCATATGCGTATCCATACGGGTGAGAAACCATTTCAATGCAAACTGTGCGATAAATGCTTCACTCAGGCCTCCAGTCTGAGTGTCCATATGAAAATCCATGCCGGCGAGAAGCCCTATCCATGTCCCATTTGTGGCAAATCTTATAGCCAGCAAGCTTATCTCAATAAGCACATACAGAACCATCAGCAGAGTCCAGAGCTGATGCATCAAATAAAGCAGGAAGAGCCACCGAAAGAAACTCTGGTGTGCATTGCTTGTGGTTCATTGCATCCAGATGCTACGTCTCTGGCCTTACACGTGACCCAACAACATGCCCAATTGTTAAATAGTGTCAAGGATATGCCTTTACCAAGTACTCAACCATTCGCTCCACTTCCACTTCCTAATCCCCAACAATTAGATACGAAATGCAGTCAACAATTGACGCCACAGCGTTTGGTACCATCTTTGATACAAATGCAACAGGATTCAGCTGGCGAAGATGAAGAGGACGATGAAGATGAGTTGGCTGGCGAGGAGCCCATGGATATGTTCTATGATATGCCCGACATGGATGTGGGCTATCAGGAAGAAGTCTGCGGTGACTTCACTGAAGATGACTATGCCGCCGAGGAAGAGGTCTACACCGAGGAGGCCAATTAG
Protein Sequence
MAVQLKHNYHHLPLTITPIFSAQQQQQQQQVIAAPSQPDLTFHCTGCSEYFVNPWALYQHMNNKHPQEEEIKPENINDDDKCPQDDGEDYSWIFEPLCELQENEEITESVESADSSTEEXXXXXXXXXXXXXXXXXXXXXSSSSSSSSSSSSTTSSSQSSASTLPTTNANTINTINTNSTNSNSSKTEPLRGLIASSKPNEFHLQINDPRESTSIILLKPEMSIIAIPPAMTPLVTPPTPPSPIAAIAQNPKRRGRRSVVPNPSINATLQPKCFQCSHCEASFLNAGDLSKHVRSHITNKPFQCSICQKTFTHIGSLNTHIRIHSGEKPYKCELCPKAFTQSSSLMVHMRSHAVRKPHQCLQCDKGFINYSSLLLHQKTHSTPEELFICPECEKEFKAEALLDEHMLMHTQELVYQCAICRQAFRASSELVQHMKCHLGEKPFTCNLCDRSFTQSGSLNIHMRIHTGEKPFQCKLCDKCFTQASSLSVHMKIHAGEKPYPCPICGKSYSQQAYLNKHIQNHQQSPELMHQIKQEEPPKETLVCIACGSLHPDATSLALHVTQQHAQLLNSVKDMPLPSTQPFAPLPLPNPQQLDTKCSQQLTPQRLVPSLIQMQQDSAGEDEEDDEDELAGEEPMDMFYDMPDMDVGYQEEVCGDFTEDDYAAEEEVYTEEAN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00501210;
90% Identity
iTF_00612225;
80% Identity
-