Dvul025863.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila vulcana
Gene Symbol
-
Assembly
GCA_008042555.1
Location
VNJP01005388.1:15643-20073[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.0013 0.18 12.9 1.5 1 23 207 229 207 229 0.96
2 20 1.8 2.4e+02 3.1 3.8 1 21 236 256 236 258 0.84
3 20 0.086 12 7.2 0.2 2 20 291 309 290 310 0.95
4 20 0.19 26 6.1 2.8 1 23 385 408 385 408 0.95
5 20 0.12 16 6.8 2.5 1 23 449 471 449 471 0.98
6 20 0.093 13 7.1 0.0 2 23 484 505 483 505 0.96
7 20 0.0013 0.17 13.0 0.9 1 23 586 609 586 609 0.97
8 20 0.00092 0.13 13.4 1.1 2 22 620 640 619 640 0.94
9 20 0.083 11 7.3 4.4 1 23 649 671 649 672 0.94
10 20 0.00044 0.059 14.4 1.5 2 23 693 714 692 714 0.97
11 20 1.2e-05 0.0017 19.3 4.3 1 23 721 743 721 743 0.98
12 20 0.0058 0.78 10.9 0.6 1 23 878 901 878 901 0.91
13 20 0.0029 0.39 11.9 0.7 2 22 909 929 908 929 0.94
14 20 0.031 4.2 8.6 3.8 1 23 938 961 938 961 0.93
15 20 2.8e-05 0.0037 18.2 1.4 2 23 980 1001 979 1001 0.97
16 20 6.4e-05 0.0086 17.1 0.8 1 23 1008 1030 1008 1030 0.98
17 20 0.063 8.5 7.7 0.0 2 21 1057 1076 1056 1077 0.92
18 20 0.027 3.6 8.8 4.0 1 23 1124 1147 1124 1147 0.96
19 20 0.034 4.7 8.5 2.9 1 23 1184 1207 1184 1207 0.97
20 20 0.0003 0.041 14.9 1.4 1 23 1232 1255 1232 1255 0.97

Sequence Information

Coding Sequence
ATGCTTCCCTCAAATATTTGCCGCACTTGTGCGGTTCAGAACACGGATTTGCGGCCCTTGTCCACCTGTCTGGCCAAAGACGCCTCAAAAAGTTTCTATGATGTGCTCCAGGAGCTAACGCAAATCGATCCTCTGGTTGAAAGCTCGGGTGACAATCTGCCGCAGCATCTGTGCACCGACTGCCTGGCGAGATTGGAAAGTGCCTACGCGTTTGTAGAACAAGCCAGAAAGGTCAACGGCGAGCTGTTGGTTCGTTTGCGGGAATGCCTCGATGAAATGCCCATTGACATTccccaggagcagcaggcacaCATCAAAACCGAAGTAGATATCGATGAGGCGACTTCTAAGTTTGTTGTGGATGTAGATTCGTCTGTGGAGTTCAAATGGCAGCCGGAAAGTGACAGCGATAGGAAATCTGCTGGAGCAGCATCCAGTGATGAGAATGATGTCGAGAAGAAGCCGTACTCTTTAAGGCGCAGCGCGCGTAAAATCAAGCAACCtttagataataataatgaagagACTGAGTTGCCAACAGAACCATCGCCCAGCAAACGCCGACGAGGCCGTCCGCCCGGCCCGGCCAAGTCCCAATCAATGACCTCCGATGGTCGTCACGCCTGCAAGGTGTGCGGAAAGACCTTCTCCTGGTTCCGCGATATGCAACGCCATGCCCGCATCCATTTCGAGAAATCCAATGCGTTCGTTTGTGACACCTGCGGCAAGGGATTCCTACGCAAGGACAAGTACACATTCCATCTGCGATGCCACGAAAAGCGAGCGAAAGCCAAATGCCAGGCTCTGCAAGGAGGTAAAGAGTGGCGCTTCGCCGAACGGCTGTACAGTTCCGGCAGGCTGAAGAGAATCGAGTGCAAGCTGTGTGGCCTAAAGTGTCCCCGAATTCAGGAGCTTAGAACTCACTTGGTCTGCCATCAGAACGTGGAGAGCCTGCTCCAGTTGAGGGAGAACAGCGATGTAATACAGGAGCACTATGCCGATCAGTCAGTCGACTTGGATGTCGTCAAGCAGCAAATTATCAAGGACCTAACAGCGGGGCACTTGGAAAAGTTTGCTTCCGTGGTGAATTTCCATGGCTACGAGTTGGGATTGGATGACTCGGACGAGGAATCTGCCAGCGGAGAGTCCAAATATGAGTGCACGGCGTGCCATCTATATTTAGAGAGGAAACATCAACTGGTGAGGCACACACAAGAGGAGCACGCTCAATCCTCGCCTTCAGAGCTTCCCTGGCAACGCTGCGGCTTGTGTAAAATTGGATTCCTCTGCTCCAGACTCTACGACAGCCATGTGAAAACGCAGTGCGACAACAAACTGAAGCGATATCAGTGCGCAAAGTGCCCGGCGAAGTTTATGTGGTCGGAGAATCTGCACAGGCACGCCTGTTCCCATCGCCACCAGGAAGCAAGGACGTCTGCCCGCCAAATCTCCTGCTCTTTGTGCGATGAACTACTGCCCACATTGGCCCAATTGCGTATACACTTGGTTACCCACCAGAGAAACATGAGTGGCATCGATTCGGAGCACAGTTCCACATTCTTTCGGTCCTTCTATCCCAACGGACTGGACTGCACCCCGGAGGAGTTGGGTGTCCGCATTGCCGAGGACTTTGAGGTGCAGGACTTTGATCGCTACTACAACGCCAGCACGGGCAGTGGCCAAGAGCTGGATCTATTCGATTCCGAGACGGAGCAGAGCGGTGATGATCGAGAGGAGGACGAGAAGCCGACCTGCCACACCTGTTTGCTGTGTGGCGAGGTGACGAGCAGGCTCACGACCCTGCTGCAGCACCAGAACAGAGTCCATTCAATAGCGACGACGAAAGATTTGCCTTGTTCCTGCCACGACTGTGGTGCTAGCTTCATAAGCGATGCCCTGCTGCAACAGCACCGGCGGCGTATCTGCGGCAAGAAACACTTCCGTCATCACTGCCCGAGCTGCAATCTCCGGTTCATCTGGCCGAGCAACTATGAGCTGCATCTGAAGACCCACCATAATAGCCacttggaggaggaggatcaaCTCGAGGAGGGTGAGCAGCGGGACGCCAAGCTGCAGTGCGACGAGTGCGATAAGGTCTTCGTCTGGCACAAGGATCTCACGCGTCACAAGCGCCTGCATCTGCCGCAGTTGGCGCGATTCGAGTGTCCGCATTGCGAGCGAAAGTTCCACCGCAAGGATGGCCTCAAGTCCCATTTGCGGGTCCATACAGAGGAACAGGTGGTGGAGCAACCTCTTACAACCGACAGCAGTGAGGTTCTTGCCCTGCTCTCCCGTTCCCATGGCTGCAAGCAGATCCAATGCATGATCTGTCTCTCACATCACTCCAAGATCTCTGATCTGCGAACCCACTTGGGCGCCCATCAATACGGATTGAGCTTTTCCACAGAGACCGATATTTCCAGTATATCAAAGTCGCTGTATCCGGAAAAGGGAACGGTCTTGGGCAGAGATGAACTGGCGGAGAGAATTATGGCAGATATCGAACAAGGACTAGAGCTGGATCGATTTATTTCCATTACCAATGAGGCTGGGTTGGAGCTCAACTTGGACAGCAGCGAAACGGACACTGAATCCGAGCAAGAGGAGAATGAGACGTCCAATCAAAACTACGCCTGCAATCTCTGTCCCACGGAGGTGAAGAGAAAGCATCAGCTTTATGCCCACCAAGGGGAAAGCCATCAGTGGGAAGAGGCGACGCTCGTTTGCTCGCACTGTCAGGCTAGGTTTGTCAGCGAATCCCTGCTGGAACATCACTCCCGAACCTTCTGCAACAATGTCCAGAAGCGCTTCCAGTGCCGCAAATGCCCGCTTCGCTTCCGCTGGCGTGAGAACCTGAAGCACCACCTATATTTGTTCCATCAGCAGGCCGAGATGCCAGTTGGAGAGGATTCTTCGCAAGCGGATGCCGAACTGCAATGTGGCGAGTGCCAGCGAACGTTCAAGATGCAGAAGGATCTCACACGGCACACCTTGATGCACGCCCGGGAGGCGACGATCTATCGGTGCCGCTGGTGTGCTCGTCGTTTCTACCGCTGGGCCAATCTCCTACAGCACATTTCACGCCACGGCATTCGGGCTAGTGAGTTGCACTATGCCGAGGCTATCCTGGACTCCTATGGACATCCAGGCGGTCAAAAAATCGTCGAATGTCGGGTGTGCAATGTCAGCTTCGCCAGTATCGCCGCCCTGCGACTGCATCTGGAAACCATGCCGGCAGGGAGCCACCATGAACTCTCCTCATTGAAGAACTACTCAATCACCAATCAAATGGGCTTCGAGCTGGAGCTCCAGGACTCGGAAACGGATGAGGAGCAGCAGTCAAAGCCGCCCGGTGTGCCTGCCTACTACACGTGCGGTATGTGCCAGTTGAGGTGCGTACGGAAATTCGAGctgcaccagcaccagcaggcCATGCATCGGCTGGAGAAGATTCCCGACGGTTGTGATCAGTGCATCTTCAAGAGCGTCTGTCCCGATCTCATTGCCCATCACAAGAGGACGCAGTGCGGTAACCGGGAGAAGCAGTTCACGTGCTCCCGCTGCAACTATAAGTTCATGTGGGAGTCAAACCTGCTTACCCACATGCATATGCTGCACGGCAAGACGGACGCTCCGGAGCAGGAGGAAGGCAAGCAGGAGGCTGATGAGCCTAAGGCCGGAAGCCCCGTTTTCCAGTGTGCCCTGTGCCCCAGGAAGTACAATCGAAAGGACCGGCTTACGGCGCACGTGAAAAAGTTCCATGGGCCCGATGGCAAGGGCCCCGAGGTGGGAACGGCATTGAAAAACCATCGCCTGCAGCAGGGACACTTCGAGGAGGGTCAGAATTCTGGGGAACCAGCCAGGCGCACGGTTTTGGAACAGTTTACTGTATGA
Protein Sequence
MLPSNICRTCAVQNTDLRPLSTCLAKDASKSFYDVLQELTQIDPLVESSGDNLPQHLCTDCLARLESAYAFVEQARKVNGELLVRLRECLDEMPIDIPQEQQAHIKTEVDIDEATSKFVVDVDSSVEFKWQPESDSDRKSAGAASSDENDVEKKPYSLRRSARKIKQPLDNNNEETELPTEPSPSKRRRGRPPGPAKSQSMTSDGRHACKVCGKTFSWFRDMQRHARIHFEKSNAFVCDTCGKGFLRKDKYTFHLRCHEKRAKAKCQALQGGKEWRFAERLYSSGRLKRIECKLCGLKCPRIQELRTHLVCHQNVESLLQLRENSDVIQEHYADQSVDLDVVKQQIIKDLTAGHLEKFASVVNFHGYELGLDDSDEESASGESKYECTACHLYLERKHQLVRHTQEEHAQSSPSELPWQRCGLCKIGFLCSRLYDSHVKTQCDNKLKRYQCAKCPAKFMWSENLHRHACSHRHQEARTSARQISCSLCDELLPTLAQLRIHLVTHQRNMSGIDSEHSSTFFRSFYPNGLDCTPEELGVRIAEDFEVQDFDRYYNASTGSGQELDLFDSETEQSGDDREEDEKPTCHTCLLCGEVTSRLTTLLQHQNRVHSIATTKDLPCSCHDCGASFISDALLQQHRRRICGKKHFRHHCPSCNLRFIWPSNYELHLKTHHNSHLEEEDQLEEGEQRDAKLQCDECDKVFVWHKDLTRHKRLHLPQLARFECPHCERKFHRKDGLKSHLRVHTEEQVVEQPLTTDSSEVLALLSRSHGCKQIQCMICLSHHSKISDLRTHLGAHQYGLSFSTETDISSISKSLYPEKGTVLGRDELAERIMADIEQGLELDRFISITNEAGLELNLDSSETDTESEQEENETSNQNYACNLCPTEVKRKHQLYAHQGESHQWEEATLVCSHCQARFVSESLLEHHSRTFCNNVQKRFQCRKCPLRFRWRENLKHHLYLFHQQAEMPVGEDSSQADAELQCGECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHISRHGIRASELHYAEAILDSYGHPGGQKIVECRVCNVSFASIAALRLHLETMPAGSHHELSSLKNYSITNQMGFELELQDSETDEEQQSKPPGVPAYYTCGMCQLRCVRKFELHQHQQAMHRLEKIPDGCDQCIFKSVCPDLIAHHKRTQCGNREKQFTCSRCNYKFMWESNLLTHMHMLHGKTDAPEQEEGKQEADEPKAGSPVFQCALCPRKYNRKDRLTAHVKKFHGPDGKGPEVGTALKNHRLQQGHFEEGQNSGEPARRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00491633;
90% Identity
-
80% Identity
-