Basic Information

Insect: Drosophila virilis
Gene Symbol: indra
Assembly: GCA_007989325.2
Location: CM017606.2:10407659-10412967[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.082 4.9 7.5 0.3 1 23 265 288 265 288 0.96

2 7 0.0006 0.036 14.2 0.8 1 23 296 318 296 318 0.98

3 7 0.00031 0.018 15.1 0.3 1 23 375 398 375 398 0.98

4 7 2.8 1.7e+02 2.7 6.2 1 23 406 429 406 429 0.97

5 7 0.073 4.4 7.6 0.8 2 23 795 817 794 817 0.95

6 7 0.47 28 5.1 0.1 2 19 822 839 821 842 0.91

7 7 0.14 8.3 6.8 1.2 3 23 851 874 849 874 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.082	4.9	7.5	0.3	1	23	265	288	265	288	0.96
2	7	0.0006	0.036	14.2	0.8	1	23	296	318	296	318	0.98
3	7	0.00031	0.018	15.1	0.3	1	23	375	398	375	398	0.98
4	7	2.8	1.7e+02	2.7	6.2	1	23	406	429	406	429	0.97
5	7	0.073	4.4	7.6	0.8	2	23	795	817	794	817	0.95
6	7	0.47	28	5.1	0.1	2	19	822	839	821	842	0.91
7	7	0.14	8.3	6.8	1.2	3	23	851	874	849	874	0.90

Sequence Information

Coding Sequence: ATGAGCGGCAATACAAAAAAGGAGTTAATCCTTTGCGACTATTGCCAAGTCGCAAAAGATAGCAATCAGATTTACACAAACAGAAAGCAATTTGCCGGCTGCCGAATCGTTGACCTTCTACAAAGTGTCACCCAACGCACCATACCGCTCCCAACAACTGTTAAATTGTGCAGCCTGTGCGCCTCAACTTTGCATGCCACAACCGGCACCATCGCCAGAGCCATCGAGTTGGTGTCCAAGCTGACGCAGACTGGCAAGAAGCAGAACATTGAAACAGTCCTTGTTGAAGCCGAGTCAGATGACACAGACGACGGAAAGCGAACAAAGCCTGCCACAAACATTGATTCACCGGCAGCCAAAGAGCGCATGTCAAAGGGCGCCGCAACTACCAACGGCACGCCCATTGTTGACCTGGAGAGCCCCAAAGTGACGCCTGCTAAGGAAAAAGGCACGCCAAACAAGACTCCAGCCACAAAGAAAGGACTCAAAGAACCAAACAGCTCGGCAGTGGGCGTCCAGCAGAGTCCTAGAAAACAGGCTCTCAAAGCAAGTCTGCCACAAACTAGCACACCTGCGGCATCAGCACAACCGTCCACTCCAAAGAAGGTAGAAGACTTGCTGCAGAATGCAATCAAGTTGACGCCCGCCAAGGATGTGCCCAAAAAGAATAAAGATTTTATACAGCTTTTTGGTGGCAACGCTGACAATGCCAGCGACACCGAGGAGGAGGACGAGGAAGATGACGAGGTGACGACAGTCGGGAAGGCAGAAATTAAGAATATAGCAACCGGCTTCGAGTGCAAGCTATGCGACTTTGCATCCGTCTACCCAAATCCCATGAAGAAGCATTTGAAAGAATTGCACGGACAGAAGCGTCCGCGCATCTACAACTGCATGAAGTGTACCAAAGTCTTTGGCGTGCTGAACTCCCTAAAGTCGCATCTGCTGACACACGGCATTACCGAGGAGAAGGATGAAAGTGCAGCACCAGACCCACAGCTTGCAGTGCTCACGGCActgaagccaaagccaaaacctTCCAATACCGAATATACCTTTGCCATCAATAACACCAACTCGTCTACACCAAAGCCCGCCGGGGAGCAAGTGCAAGCTACCACATACCAGTGCGAGATATGTCATCTGGATTTCAGCGCGGTCAAAGCTCTACAGGAGCACATTAAGACCGTGCATAACATTGAGCGTCCCAAAGCTTTCAAATGTGATGCCTGCGATTCTCATTTCATGCACAAAGTCACAATGGATCGCCACTACAAGAAGAAGCACTGCGGCGAGGATGCCGCTGCGATGCCGGCTAAAATAAAAGGTAGACGCAAAACCATTTCGATTGTGGTTAACCGGCCGCCCAGCAAGGAAGAGGCCACCCCGCTGGCCAGTTCGCCAGCAAAGATTACAGGCAGACGCAAGACGATGGCAGTCGAGCTGAATGAAACAGAGGAGCCGCCGGCCAAGTTGAAAAGGCAATCACCACTAAAAGAGCCAAAGAAATTAAGCGAGATAGACACTGAGACAGCCCATAAGGAACCCATTGAAGAGCCAGCCTCACCGAGCAAGAGCAAATCAAAAGTGGACAAGTTGTCTGAGAGCGCAACTGTTGACAATGTCACGAGCGAGTCAAAAGTGGACAAGTTGTCCGAGAGCTCAACTGTTGACAAAGTCGCAGGCACGCCCAAAAAACCCAAGAAGCCATCACAAGTGCTCAAGGATTTCTTTGCGCCGAAGCTGGCCTCGCCAGCCAAGAGCAAATCAAAGGCCAACGACGAACAGGTCGCGCCCACACTCAGCCAAGAGAACGAGATCATAGAGGAGCTGAATAATATGGATCTAAATGATATTGATCTGCTGGACTCATTTGACGTCGACATATCCAGCAATAAAATGAAGTCCAAGAAAGATGTAGATACGACAAAGTCGTCATCACAAATCACAGAAATCGACTCGCCAAGCAAAAAGGTCAAATCATCGAATGAAGTAAATCCGCTGGAGCCTGTACAGAAGAAAATTAAGTCCAAAAAAGATAAAGATACAGTCGATTCATCACAAATTGTAGACAGCAACGAAGAGAAACTTACAAATGAAATAGATCCGCTGAACTCATCGCAGCTCATATCCATCAATGGCACGCCAAAGAAGTCGGGCAAACGCAAGGCAGCCAAACAACAGGCAGAGGAGTCATCACAAGCGGACACCGCCGATGAGGAAGTGGCCAGCCCAGTGCAGCTGAAGCCGCTGAAGAAATCGAAGAGCGACAAGCAGAAGATGACAGACAGTGATATCGAGCTGATCGACGAGATCAATCCCAATGTCAAGCCACACAAGCGCACAAAGCTCGACTCGATGGTGCTCTCCGAGTCGGAGCTGAGCTGCAGCATGTGCAGCAAGGTGGTTGGCTCACGCAAGCGTCTCGATTCGCATATGCTCAAGAAGCATACCACAAAACTGACATGCCCCAATTGCAAGGTGGCCTATAACGACAGCTTGGAGTACGTTAAGCACTTCTCGGTCTGCAACGGCGTCGACGGTCTACCGTGCGGCTACAAAAACTGCAAAAAGGTCTTCGCAGCGGCCAATTTCCTGTGCTCCCACTTGAACAAGAAACACAAACTCGCGAAGTAA
Protein Sequence: MSGNTKKELILCDYCQVAKDSNQIYTNRKQFAGCRIVDLLQSVTQRTIPLPTTVKLCSLCASTLHATTGTIARAIELVSKLTQTGKKQNIETVLVEAESDDTDDGKRTKPATNIDSPAAKERMSKGAATTNGTPIVDLESPKVTPAKEKGTPNKTPATKKGLKEPNSSAVGVQQSPRKQALKASLPQTSTPAASAQPSTPKKVEDLLQNAIKLTPAKDVPKKNKDFIQLFGGNADNASDTEEEDEEDDEVTTVGKAEIKNIATGFECKLCDFASVYPNPMKKHLKELHGQKRPRIYNCMKCTKVFGVLNSLKSHLLTHGITEEKDESAAPDPQLAVLTALKPKPKPSNTEYTFAINNTNSSTPKPAGEQVQATTYQCEICHLDFSAVKALQEHIKTVHNIERPKAFKCDACDSHFMHKVTMDRHYKKKHCGEDAAAMPAKIKGRRKTISIVVNRPPSKEEATPLASSPAKITGRRKTMAVELNETEEPPAKLKRQSPLKEPKKLSEIDTETAHKEPIEEPASPSKSKSKVDKLSESATVDNVTSESKVDKLSESSTVDKVAGTPKKPKKPSQVLKDFFAPKLASPAKSKSKANDEQVAPTLSQENEIIEELNNMDLNDIDLLDSFDVDISSNKMKSKKDVDTTKSSSQITEIDSPSKKVKSSNEVNPLEPVQKKIKSKKDKDTVDSSQIVDSNEEKLTNEIDPLNSSQLISINGTPKKSGKRKAAKQQAEESSQADTADEEVASPVQLKPLKKSKSDKQKMTDSDIELIDEINPNVKPHKRTKLDSMVLSESELSCSMCSKVVGSRKRLDSHMLKKHTTKLTCPNCKVAYNDSLEYVKHFSVCNGVDGLPCGYKNCKKVFAAANFLCSHLNKKHKLAK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00526931;
90% Identity: iTF_00563518;
80% Identity: -