Basic Information

Insect: Drosophila virilis
Gene Symbol: -
Assembly: GCA_007989325.2
Location: CM017604.2:7489152-7491120[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 8.8 5.2e+02 1.1 0.1 1 8 56 63 56 65 0.84

2 7 1.1e-06 6.6e-05 22.8 0.3 2 23 181 202 180 202 0.96

3 7 7.8e-06 0.00046 20.1 0.1 1 23 208 231 208 231 0.98

4 7 1.7e-06 0.0001 22.2 2.5 1 23 237 260 237 260 0.98

5 7 0.00027 0.016 15.3 2.2 2 20 267 285 266 288 0.93

6 7 2.5e-05 0.0015 18.5 1.8 1 23 294 316 294 316 0.97

7 7 0.012 0.73 10.1 0.1 1 20 322 341 322 346 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	8.8	5.2e+02	1.1	0.1	1	8	56	63	56	65	0.84
2	7	1.1e-06	6.6e-05	22.8	0.3	2	23	181	202	180	202	0.96
3	7	7.8e-06	0.00046	20.1	0.1	1	23	208	231	208	231	0.98
4	7	1.7e-06	0.0001	22.2	2.5	1	23	237	260	237	260	0.98
5	7	0.00027	0.016	15.3	2.2	2	20	267	285	266	288	0.93
6	7	2.5e-05	0.0015	18.5	1.8	1	23	294	316	294	316	0.97
7	7	0.012	0.73	10.1	0.1	1	20	322	341	322	346	0.88

Sequence Information

Coding Sequence: atgcgtCGCTGTTACCTGTGCAACTGCAGCTTCGCGGACGGAAAGGTGTACGAGCACATGTTCGAAAAGCGCTGCAATGCGTCGGGCGACGAGCAGCAAACCCTGGCCAACATCTTGGCCATGGTGCTGGGCTATCAGCTGCAAGAGGAGCACTTGCACTCGTCGTTTGTGTGCAGCATCTGCAAGGTGAGCCTGCTCAACTATGAGGAAATGGCGCGTCAATTGTTGGCGGCACGCCTGGAAATAACGGAGCTGCACAAACGCACAGTCCGGCTGTATGAGGCACGTCTCAATGACGACAACAGTTTGGAGTCGGACCTTGTGGAAGAAGATCGTTCGGCGTCAACGGATTGTGCTATTGTGGATCGGTGCTTCGAGGAAAGCGAACTGCTTGAGCAATGCTCTGAAGATATGGACCTGATAGAGCAGTGTTCCGAGGAAACGGATTCCGTGGACAAGTGCTCCGAAACAGAGGACGAGCAAAGCTTCAGCTCGCAGCAGCCAGttgcagttgccgcagTTGCACGCCCGAACAGCCTGAGCTGCACGTATTGCGGCAAGACGTTCGCCCGCCGTCAGGGTCTGGAGGAGCACGAGCGCGTCCATACCGGGGAGCGGCCATACAAATGCGCCCTGTGCGGCGCCAGCTTTGCACAGCGCGCCAACTGGCGCACACATCTGCTGACCATACACCAGAACCAGGCGAACTTCAAGTGCGGCCAGTGCGAGCGCAGCTTCAAGCGCAAACGTCTGCTGGAGAATCACATCAAGTCGAAGCATACACAGCTGCGCGACCTCAAGTGCGAGCACTGCGAGGCGACGTTCACGAATGCGGTCAATCTGCTGAAGCATCTGCTGTGCCACAGCGGCGAGAAGAACTACAGCTGCCAGATCTGTGGCAAGCAATTCAGTCGCGCCGAGAATCGCAATGTGCATCATTTTGTGCACAGCATACGCAAGCCATATGCCTGTATTGTCTGCGATGAGGGCTTCATGCGcaagcagcagctccagcagcacaTTGTCGAGCAGAAGCATCCCAATCCGAAGATCGTGCGTCGCAAGCCACAGTTCAGTGCGGCCAACAGCGACAAGCTGCTCCAACGGCCACTGGGCGAGGCCAACAAATGA
Protein Sequence: MRRCYLCNCSFADGKVYEHMFEKRCNASGDEQQTLANILAMVLGYQLQEEHLHSSFVCSICKVSLLNYEEMARQLLAARLEITELHKRTVRLYEARLNDDNSLESDLVEEDRSASTDCAIVDRCFEESELLEQCSEDMDLIEQCSEETDSVDKCSETEDEQSFSSQQPVAVAAVARPNSLSCTYCGKTFARRQGLEEHERVHTGERPYKCALCGASFAQRANWRTHLLTIHQNQANFKCGQCERSFKRKRLLENHIKSKHTQLRDLKCEHCEATFTNAVNLLKHLLCHSGEKNYSCQICGKQFSRAENRNVHHFVHSIRKPYACIVCDEGFMRKQQLQQHIVEQKHPNPKIVRRKPQFSAANSDKLLQRPLGEANK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00551080;
90% Identity: iTF_00534792;
80% Identity: -