Basic Information

Insect: Drosophila virilis
Gene Symbol: -
Assembly: GCA_007989325.2
Location: CM017608.2:8404533-8410976[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0002 0.012 15.7 3.4 1 23 291 313 291 313 0.98

2 11 0.00098 0.058 13.5 10.5 1 23 319 341 319 341 0.96

3 11 9.9e-05 0.0059 16.7 6.5 1 23 347 369 347 369 0.98

4 11 0.00045 0.027 14.6 1.6 1 23 375 397 375 397 0.95

5 11 2.1e-05 0.0013 18.8 0.5 1 23 403 425 403 425 0.97

6 11 1.4e-05 0.00084 19.3 0.1 1 23 431 453 431 453 0.98

7 11 0.00012 0.0072 16.4 2.0 1 23 458 481 458 481 0.97

8 11 0.05 3 8.2 0.3 1 23 487 510 487 510 0.94

9 11 0.00016 0.0096 16.0 0.1 1 23 568 590 568 590 0.98

10 11 0.015 0.87 9.8 2.7 1 23 703 725 703 725 0.95

11 11 0.0043 0.26 11.5 4.9 5 23 738 756 730 756 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0002	0.012	15.7	3.4	1	23	291	313	291	313	0.98
2	11	0.00098	0.058	13.5	10.5	1	23	319	341	319	341	0.96
3	11	9.9e-05	0.0059	16.7	6.5	1	23	347	369	347	369	0.98
4	11	0.00045	0.027	14.6	1.6	1	23	375	397	375	397	0.95
5	11	2.1e-05	0.0013	18.8	0.5	1	23	403	425	403	425	0.97
6	11	1.4e-05	0.00084	19.3	0.1	1	23	431	453	431	453	0.98
7	11	0.00012	0.0072	16.4	2.0	1	23	458	481	458	481	0.97
8	11	0.05	3	8.2	0.3	1	23	487	510	487	510	0.94
9	11	0.00016	0.0096	16.0	0.1	1	23	568	590	568	590	0.98
10	11	0.015	0.87	9.8	2.7	1	23	703	725	703	725	0.95
11	11	0.0043	0.26	11.5	4.9	5	23	738	756	730	756	0.92

Sequence Information

Coding Sequence: ATGTGCGCTGCACAGAGCAATCCGCCGCCCTTCGGCTACACTTGGGGTTTTGCAGACAACGGCAATCGTGCCGCAGAATCAGTTTTGGAGATATCGCCAAATATTAACTACACTGTCAGTGGGGAATCGATGCCCTATCTGTTATCCACGGATGGATCATTGGCCGTACAAAAGGATGTTAAAGGTGCACTCAGCAGCAATAAGGGCAATGTCGTTCGGCGCATGTTCGTGGTGAACGATTCCTCATTTGCGCCCGGAACACAAAGAGTAATTACCACAGGCTCCGCATCGACGGTGGTCAAAAAACAGGACTCTGGTCAACAGGTGTTGAGCATAAATTCGCTCGATAAGAACTATCTTTTGGTCGATcaggcaacagcggcagcagctgcggctgcagcaggTGGAGGTGATCCGGCGTCTGCTGCACATCATCATACATTGACAAATGGCAGCATTGTTGATGCCAAAACTGGACAAACGGTATTGACCACATCGGGTGCTGCCGCGGCCGCGGCCAAATCGCATTTTAGCTCAATTGGTGCACTGCATCTGACCCAAGAGGAATGCAATGAGATCTTAATCAAGCGCGCCATTGCAGCCGGCCACGGCCACCATCAGACGCACACAATCACCGCTGGCGACGGAgcgcaccaccaccaccaccaccaccatcaTTCGACGGCGCCAGGCGCGACACCAATTCAAGTACAGAAAGTAATACAAGGACTCGAAGAGAACGAGGACTCGCAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAATTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACCGACGCCACCATCAAAAAGGAGCGCCCGTACAGTTGTGACGAGTGCGGCAAATCCTTTCTGCTCAAACATCATTTGACAACACACGCACGCGTGCACACAGGCGAACGTCCACACATTTGCACCCATTGcggcaaaagttttgcgcaCAAACATTGTCTAAATACGCATCTACTGCTCCATTCGACGGATCGGCCATATCAGTGTCAGGAGTGCAAGAAGAGCTTTACGCTTAAGCATCATCTGTTGACGCATTCGCGTGTCCATAGTCGGGAGCGGCCATTTGTGTGCCAGGAGTGCGGACGTGCATTTCCCCTCAAGCGTCATCTGGTCACGCACAGTAAATTTCACGCCGGCGAACGTCCCTACGTCTGCGAGGAATGCGGTGAGAGTTTCGCACAGGAGAATCACCTGATTATGCACTCGCGCTTTCATGGTTCATTGAATCCATTTGTTTGTGCTGATTGCGGTGCCTCGTTTCCACGCAAATTTCAATTGGTTAATCACGGACGCATACACGGCAAGATACCACACTCCTGCACAGTTTGCGGCAAAGAATTTCTACAGAAGCGCACCCTAGTATCCCACATGAGGCGCGTACATACCGGCGAGCAGGCGCATCCCTGCGTCAGCTGCGGCGAAGGTTTCCTCACCAAGGCGGAACTGCATCAGCATGTCCGTGCGGCGCACAACGGCGTCAATCCCAATACGAGCAGTGCCACCATTATAGCCAATCAACAGATACAACAGCCGCATCATCATCCAGGACATCCGCAGACGATCACCGTTGTCAGCAATCCGGCTAATTCAACGCTGCTCACCGTCTCCACAACCGATGCCAATGGCGTTGCGCGTCCACAATTCGTTTGCCGCGAATGCGGCAGCGCGTTTAACAGCCGGGAGGCGCTCGCCTTGCACTTGCGACTGCACACGGGCGACAAGAGCCTTATGACCGATCTGTGCGCTTTGACAGCAGCGCTGCCCGGTCACTTTTTGAGCACGGCGAGCCTCAATCCGGGCACTGTGGTAACGGCCAATCCAAATTTGGTGGGCCAGAGTCCGGTGCCGGTGCAAATCATATCATCCACCGGTCAGGTGATGTCGCAGACCACGCTGGTGCAGGCCGCCAATTCGACCCATCCGCAAGCGGTTGTCACAGCCGTGCCCACAATGCCCGTCCATGGGCAACAGCATCTGCAGCAcatccagcaacagcagcagcaacagcatgtGGTCACCGTATCGCCGGCCAACAAGCCAAAATCGCATTTCTGCGCCAGCTGCGGCAAGGGATTCGCCGCCAAGCACGGCCTCATGCAGCACAATCGACGACATCCAAACGGCGGCTGCACGGTGCGCACCCATGTCTGCGAGTGTGGAAAGGCATTCTTCCAAAAGAACCATCTGATGCTGCATCAGCGCCAGCATTTGGAAACAAAGCCAGCCATATCGCAGCAACAGGTATGCTAA
Protein Sequence: MCAAQSNPPPFGYTWGFADNGNRAAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGALSSNKGNVVRRMFVVNDSSFAPGTQRVITTGSASTVVKKQDSGQQVLSINSLDKNYLLVDQATAAAAAAAAGGGDPASAAHHHTLTNGSIVDAKTGQTVLTTSGAAAAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHGHHQTHTITAGDGAHHHHHHHHHSTAPGATPIQVQKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGERPHICTHCGKSFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCADCGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRAAHNGVNPNTSSATIIANQQIQQPHHHPGHPQTITVVSNPANSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHGQQHLQHIQQQQQQQHVVTVSPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQVC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01556276;
90% Identity: iTF_00803779;
80% Identity: -