Basic Information

Insect: Drosophila virilis
Gene Symbol: hang
Assembly: GCA_007989325.2
Location: CM017604.2:17870301-17890659[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.28 17 5.8 1.0 3 23 370 391 369 391 0.93

2 17 0.81 48 4.4 3.2 3 22 498 517 496 517 0.89

3 17 0.0006 0.036 14.2 3.3 1 22 615 636 615 638 0.90

4 17 0.069 4.1 7.7 0.1 2 21 650 669 649 670 0.93

5 17 0.0007 0.041 14.0 0.2 2 23 797 819 796 819 0.95

6 17 0.002 0.12 12.6 0.1 1 23 827 850 827 850 0.96

7 17 0.00015 0.0091 16.1 0.2 2 23 932 953 931 953 0.97

8 17 0.00029 0.017 15.2 2.9 2 23 1072 1094 1071 1094 0.97

9 17 0.023 1.3 9.3 0.2 2 23 1103 1125 1102 1125 0.95

10 17 0.0044 0.26 11.5 0.6 1 23 1138 1161 1138 1161 0.97

11 17 0.00013 0.0074 16.4 1.1 1 23 1202 1224 1202 1224 0.99

12 17 0.0019 0.12 12.6 0.9 1 23 1232 1255 1232 1255 0.96

13 17 0.068 4 7.7 0.4 2 19 1263 1280 1263 1281 0.94

14 17 7.2e-05 0.0043 17.1 0.4 3 23 1379 1399 1378 1399 0.98

15 17 0.0051 0.3 11.3 0.1 1 23 1434 1456 1434 1456 0.97

16 17 0.00059 0.035 14.2 0.6 2 23 1546 1568 1545 1568 0.93

17 17 0.0064 0.38 11.0 0.3 3 23 1624 1644 1624 1644 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.28	17	5.8	1.0	3	23	370	391	369	391	0.93
2	17	0.81	48	4.4	3.2	3	22	498	517	496	517	0.89
3	17	0.0006	0.036	14.2	3.3	1	22	615	636	615	638	0.90
4	17	0.069	4.1	7.7	0.1	2	21	650	669	649	670	0.93
5	17	0.0007	0.041	14.0	0.2	2	23	797	819	796	819	0.95
6	17	0.002	0.12	12.6	0.1	1	23	827	850	827	850	0.96
7	17	0.00015	0.0091	16.1	0.2	2	23	932	953	931	953	0.97
8	17	0.00029	0.017	15.2	2.9	2	23	1072	1094	1071	1094	0.97
9	17	0.023	1.3	9.3	0.2	2	23	1103	1125	1102	1125	0.95
10	17	0.0044	0.26	11.5	0.6	1	23	1138	1161	1138	1161	0.97
11	17	0.00013	0.0074	16.4	1.1	1	23	1202	1224	1202	1224	0.99
12	17	0.0019	0.12	12.6	0.9	1	23	1232	1255	1232	1255	0.96
13	17	0.068	4	7.7	0.4	2	19	1263	1280	1263	1281	0.94
14	17	7.2e-05	0.0043	17.1	0.4	3	23	1379	1399	1378	1399	0.98
15	17	0.0051	0.3	11.3	0.1	1	23	1434	1456	1434	1456	0.97
16	17	0.00059	0.035	14.2	0.6	2	23	1546	1568	1545	1568	0.93
17	17	0.0064	0.38	11.0	0.3	3	23	1624	1644	1624	1644	0.98

Sequence Information

Coding Sequence: atgtGCGACGCTGTCGCAACTACAatcacaaccacaacaacagcagcagcaggaccaGGAACAGGAGCAGGCACGGGAACGGTTAGTGCTGCTGCCGATACAGCGACAGCAATGGAGGAGCGTACGCGACAAAGCTGCTGTCGCCTATGCATAGCGCCCGCCAGCGAATGCATTTCGATCATTAACAGTTATGCGGCCGATAAGGAGCCACTGGCCACTAAAATACACAACTGCGTAAATATCAAGATCACGCCGTTGGATCGTCTATCGCTGCATATTTGCCATGCCTGCATCAGCTATTTGAACTCTTGGCAGAGCTTTAAGAATCGCTGCCTCAGCTCACAGTCCAAGCAGCGGCAATGGCTGGACACCGATAAAAGCAAGCAGCAGACACTTTTAGGATATTTGGATTTGAACAAAACGGAGAATGGCAGCTCAATTGAACAGCAGCACGAGACGAACATCGATTCGGCGACACGTTTGACCAAGTTTAAGCCTAAATTGTATTTACCATTGGATATATCGGTGCCACCGCTTCCACCGTTGTTGCCGCCACCGTTGCCGCCCATGTTGTCAACtattgctgctggtgctgattTGGCGCCGTTGCCAATGCCGTTGTCGCTGCCACTTGATTTCAGTCAGAGTCAGTGTCAGAATCCGAACGCGAATCAGAGTCACAAACATAGCAGTGCATTGCAgccaccgccaccaccgccgccgccgccgcctccgccACCGCTGCCGCTGGCTCCAGTTGCAGCAGTGACCAGCAACGCCTCTGgctctgccactgccactgccactgcctctGCCGCAGTCACGACTCCATTGCTAATGCCGCCGCTGCCTGCCGTGCCTATCAAGGATGAGCCCATTGACGACACGGATGATGACTTCCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCAACAATGTTCCTAGAGCGCTCCGAGCATGAGGGTGATGTGCCACTAATGACCTCCGACTATGATTACACGGCGCAGCATGGCGTGACGGCGGTTGCGGCGGCGGCATCGCTGCCCGCCAGCGCGGTTGCAAATGTGGCAGCCGCTGGCGACTCCAAGGTGGCCAGCTGTCGTgcctgcagtctgcagttctCGACGCGCGCGAATGCGCGACGCCACGAGCGCAATCTCCATCCGAATCTGTTCCAATTGTCGACAGACTCGCCAAATAATACGCCCATCACAAAACCGACGCCGGCATTGGCAGCCGCGCTGGAGATACAGCGTGCAGCTGCCGCGGCAGCGGCCACCGCGGAGGCAACAAAAGCTGCCGCTGGTGGCAACATATCAGCGCAAAAGTATCGCCAGGTGGTCATGAACACGTTCATCAAGTGCGAGAACGGCGGCTTCGACTACGACAATCCGGAACAGTATCAGCAGCTGCTGACCCGCGACAAGGTTGAGTTCATTCAGGAGAACAACGAGTTTCTGGAGCAGTACCAGACGATgacctgccgctgctgcaacaAATACTTTAACACATACAAGAACTTTATGGCGCACGTACGCAAAAAGTATCCGCTGCTGCCGCGCAATTTATGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCACTGTTCATATCGCATCTGAAGAAACGCAATTGCATCAATTTGTATCGCGTTCTCAACGCTCTCCGCGTCAAGCAGCCAAACTTCTCGCATGCCACCGCATCCGGAGCGGCTGTCTCAACCGATATGAGTGGTGTTcaaggtgctgctgctgcaggggCAACAGCACACGAAACATCAATGGAACGGCCAGAGAAGCTACGCGCCAAGGAGCTGCTGGTGAACAAACTATATGAGTGCAAGCTCTGCCCAAAGGGATTTCGCACCAAGCACGAATTCCGCACCCATGTGTATGACAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGATTGGACTTTGCCGATCCGGTAGATCGTCGCCGTCACTACAACAACATGGACTGCATTGTGCGGCTACGATGCATGACCTGCGATGCCAAGCTAGAGACGCATCAGCGCTTCCTCGATCATGTCTATCAGGATCATTTGGGCGGCGTCAGTAGCGACAATGCGTCCACCGCGAATAGCGGCATGGATCATTCGCCAGGCAAGCGTAGCCTGCTGGGCGCTCTGGGCATTGGTGTCAGTCAGTCATCCAATGATGAgtcgcgcagcagcagccacaacaacaacaatgccgtGGAAACGCCGCTAACCTCAACACCGaaaccagctgcagctggatcGGGAACTGCAGCTGCGGCGACCAGTGGCGGCTCCACATCTGGCAATCGCGATGCTCCCAAATCGCAGTATTTTTCCCGCATGCCGCAGGTGTGCCCCATCTGTGGCCAACAGtacaacaactataacaacGTGCTGCGCCACATGGAGTCAAAGCATCCCAATAAACTGCCCGAGACGTACAAATGTGTACGCTGCGGCCTTGGCTATCCGCGAATCTCATATCTGCGCGAGCACATGATTAATGTGCATGGCGTGGACAAGAATCGGCATTCCGGAGGCTTTGAGTATATTGTGAATGCCGATGCTGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTACACCGGACGCTATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGATGATGAGGAGGAAGAAAGCGGCAGCGTTGCCAAAAAGATGCGACTCgatgacagcagcaacaacagcagcatcaacatgAGCATCGCCAATCAGCAAAAGGAATGCCTCATCTGCAATGCGGTGttcagcaacaacattggGCTATCCAATCACATGCGCTCGCATTATACCGCCTCCACGACAACGAGTGCAGCGCTGGCGGCGGCCAATCGCATGACGCCAAAGTCGCTGACAATTACCGCAACGCCGCCGCTGGAAACGGCTGCCGCATCGTCCACAAGTATTGCGGTctcgacggcggcggcggcggcgggggcggcaacaacagcaacaacgcccGCCACaagcacagctgcagcagctgcgagtgcaactacaacaacaagtacaacagctgccgctgccgccgccgccgcgtcTGGCAATTTGCCGCCAGCGATGGCACATCAAACGCCACAGGAGCAGGCAGTATTCCGACGTAGCCTGGATCAGGCAGCCGATCGTCGCTTTCGGCGTATGCGCTGTCGCATCTGCCAGCGCAGATTTAGCTCGAAAAAATCGTACCGCTACCACATGCTGACCGACCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTCGCCTACGAGAAGGGCCTCAAGGTGCATCTCTTCAAGGTGCACGGACGGGCCATTAAGGATGAAATGATTGTGAAGCAGTTTGAGTGCGATATCTGCTCCATTGTCTACAGCTCTGAGCTGGAGCTGCATCAGCACAAGCGCAGCGTGCACAAGTCCCAGCTGGGGGCCGCCAGTGATGCAGCCAAGTCTAAATCGTCAGCTGCTTCCTCAACTGCTGCTGACCTTGCTGACACGTCCGGCACGGCTGTGCCAGCCCTGCCTCTCTATTGGTACCAGTGCAAGTACTGTCCATCCAATTTTAACACTAACAAAAAACTGGCCATACACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGTGGCCGTAAAAGCCTTTGGGTGCATCGCTATAAGAAGCATCCGCAGGTGCCAGATCCCGCTGAATGTACGCTGTGCCGCAAGATGTTCTTTGACCGCCAGATGCTGGAGAATCACACGCCCACCTGCAATCGAAAGCCGATCACTGCCACCGGCGCCCATCAGCAGgattcgcagcagcagcaacaacaacaacagcagcagcagcagcagctgcaactgcagcagcagcgcggcATATTCAAGCACAAAACGGGCGACGAtgacgaggaggaggatgaCGATCAGCTGATGGTGCTGGACGATGGTGTCTGCGTCGGCAGTAGCAGCAACGGTGGCAAtgctgcaacagcatcagcgTCAAGCAATGCCAATAGCAGCACATTGAAAATACGCATACCGGAGGTGGCGTGCACCATTTGCGGTGCCCGGTTCACCGATCAGGAGATGTTCAGCAAGCATATACAGAAACATGAACAGGATCTGTATGTGGATAATCCATTGGCGGCCATGTTCGATGATGGACCAGCGGACGCTGGCCAATTTCAGGTGGAGCGCCAGAACGAGAACGGGGAATATGCGTGCGATCTGTGCGCCAAGACGTTCCCCCAGGTGATAGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGaaTCCCATCATCGACGGCGAAGCGACAACgctgaacaacagcaacaacaacaacaacaacaacaacaacaattcagtGAGCTCCTCATCGATGCTCCATCTGCGCGAACTGCATGCTGTTGGCCTGATGCCCAATCAACAGCAccagaaacaacagcaacaacaacaacaactccagcagcagcagcaacaacaacaacaacaacaacatcagcaaagGAAGTCGCTGAAACGGAAACGTGAACTTAAATGCGAATATTGCGCATCCACATtcattagcaacaacaacctgcGTCGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAATCTGCCGGAGCCGCCAGTGATTGAAGTGGATGAGCCTTTAACTTGTCGCCGTTGCGGCGATCTACGGTTTGATACCAAAGAGCTGTGGATCGAGCATAAATTGGCCGATGCCAAAGTTGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAAGAGGATCCGAGGCGCCTCAACTTTGACTACGCGCGCACAGACAGCTCCAAGCTGAACGGCAATAGCAATGGCAAACAGACGCCGCAGCATCAGCAAAAGTCAAAGGGTCAGCAGGCGTCTAATTCCAGCTATACTTTGGTGGAAGGTTCCTACAGCATTACCAACAAGACGCTGGACATCTTCAAGTATATAATTATGAGCAAAACCTGGCAAAATGCAGATGCACTCATGCAAATTGTGCGCGCCCAGTCGCGTATCATGCAGGCGGCACTGCCACAAGAGACTGTCACTTCGAACATGGCACGACGCATACTGAAGCTGACGCGTGAGGAATTCGAGCTGCTCCAGGCAAAAGGTCAGCATTTTGCCGATGACTCGCAGGCTTCGCTGTCGCTACACAAACTGGTCACGCAGACCAGCGAGAATTGTGTCAGCGTGGACTACTCGGTGCCGCAGCAGGGGCTGCGTGAAGCTCTGCTTGATCATTTGCAGGAGGTTGAAACTGAACTGGAAACCAGCTCTGAGAACATAAGTGTCCAGGCCGAGGAGCACATACACTCCTCTGAAATAATACTCACGCTCGGACACTCGCGCAGCGTCGAAAACTTTCTCAAGCGGGCCATCAAGAAGCGACAACTCCTTACAATCATCGTAGCCGAGTGCGCTCCAGCCTGTCGGGGTCACAATTTAGCTGCCTCCTTGGCCCATGAGAAGAATGTGGAGATTATTGTAATACCGGATGCGTCCATATTTGCGATGATGTCGCGCGTCAACAAGGTCATCATTGGCACACACAGCGTTCTAGCCAACGGCGGACTGCGAGCCGCATGTGGCGCCTACACAGTTGCCCTGGCTGCCAAGCATTACTCAGTGCCGGTCATTGTGCTGGCGCCCATGTACAAGCTGTCACCTTTGCACTTGTGTGAGCAGGATGCTTTTAATATGGTTGGCTGCGCCGAGGATGTGATTGCATATGACTCTGTGCCGGCGCGCGATGCCAAGGTGTACAGTCCCATGTTTGACTATGTGCCACCCGAACTGGTCACGCTCTTCATATCAAATACCGGCGGTCATGCTCCCTCCTATGTTTACCGTTTGCTCTCAGAGCTCTATCATCCCGAGGATCTGGAACTTTAA
Protein Sequence: MCDAVATTITTTTTAAAGPGTGAGTGTVSAAADTATAMEERTRQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLDTDKSKQQTLLGYLDLNKTENGSSIEQQHETNIDSATRLTKFKPKLYLPLDISVPPLPPLLPPPLPPMLSTIAAGADLAPLPMPLSLPLDFSQSQCQNPNANQSHKHSSALQPPPPPPPPPPPPPLPLAPVAAVTSNASGSATATATASAAVTTPLLMPPLPAVPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRVKQPNFSHATASGAAVSTDMSGVQGAAAAGATAHETSMERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSSHNNNNAVETPLTSTPKPAAAGSGTAAAATSGGSTSGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNDDEEEESGSVAKKMRLDDSSNNSSINMSIANQQKECLICNAVFSNNIGLSNHMRSHYTASTTTSAALAAANRMTPKSLTITATPPLETAAASSTSIAVSTAAAAAGAATTATTPATSTAAAAASATTTTSTTAAAAAAAASGNLPPAMAHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSSELELHQHKRSVHKSQLGAASDAAKSKSSAASSTAADLADTSGTAVPALPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDSQQQQQQQQQQQQQLQLQQQRGIFKHKTGDDDEEEDDDQLMVLDDGVCVGSSSNGGNAATASASSNANSSTLKIRIPEVACTICGARFTDQEMFSKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSNNNNNNNNNNSVSSSSMLHLRELHAVGLMPNQQHQKQQQQQQQLQQQQQQQQQQQHQQRKSLKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDPRRLNFDYARTDSSKLNGNSNGKQTPQHQQKSKGQQASNSSYTLVEGSYSITNKTLDIFKYIIMSKTWQNADALMQIVRAQSRIMQAALPQETVTSNMARRILKLTREEFELLQAKGQHFADDSQASLSLHKLVTQTSENCVSVDYSVPQQGLREALLDHLQEVETELETSSENISVQAEEHIHSSEIILTLGHSRSVENFLKRAIKKRQLLTIIVAECAPACRGHNLAASLAHEKNVEIIVIPDASIFAMMSRVNKVIIGTHSVLANGGLRAACGAYTVALAAKHYSVPVIVLAPMYKLSPLHLCEQDAFNMVGCAEDVIAYDSVPARDAKVYSPMFDYVPPELVTLFISNTGGHAPSYVYRLLSELYHPEDLEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00479624;
90% Identity: -
80% Identity: -